Mdom007140.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- -
- Assembly
- GCA_000371365.1
- Location
- Scaffold19414:21676-28020[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.00058 0.029 14.5 1.9 1 23 230 253 230 253 0.94 2 20 0.00021 0.011 15.9 0.8 1 23 275 297 275 297 0.94 3 20 4.1e-06 0.0002 21.3 0.8 3 23 302 322 300 322 0.97 4 20 0.033 1.7 9.0 5.5 1 20 328 347 328 350 0.95 5 20 8.9e-06 0.00044 20.2 0.7 2 23 357 378 356 378 0.96 6 20 0.13 6.7 7.1 1.2 2 23 385 406 385 406 0.91 7 20 4.7e-05 0.0023 18.0 1.2 1 23 412 434 412 434 0.99 8 20 8.6e-07 4.3e-05 23.4 0.3 1 23 440 462 440 462 0.96 9 20 0.0019 0.093 12.9 3.1 2 23 512 534 512 534 0.93 10 20 0.00015 0.0075 16.4 2.9 1 22 547 568 547 571 0.90 11 20 0.47 23 5.4 3.4 2 23 654 676 653 676 0.88 12 20 0.00088 0.044 14.0 1.1 1 23 689 711 689 711 0.96 13 20 0.011 0.53 10.5 2.0 2 23 811 833 810 833 0.94 14 20 0.00018 0.0088 16.1 0.9 1 23 846 869 846 869 0.94 15 20 9.6e-06 0.00047 20.1 0.2 2 23 873 894 872 894 0.95 16 20 0.0006 0.03 14.5 4.2 1 20 900 919 900 922 0.95 17 20 1.3e-05 0.00063 19.7 0.4 1 23 928 950 928 950 0.98 18 20 0.0022 0.11 12.7 1.6 2 23 957 978 957 978 0.94 19 20 0.0043 0.21 11.8 0.8 1 23 984 1006 984 1006 0.97 20 20 3.9e-08 1.9e-06 27.6 2.3 1 23 1011 1033 1011 1033 0.98
Sequence Information
- Coding Sequence
- aTGTTGAAAGCAATTGGCCAATTACCAACGTATGAAAATGTCAAATGTGGTGAAATATTCTGTGTCTCCTCGCCGCCAGCCGTATTCAATGTTACTTGCATTTTGTGTGACCAAAAAATAAGCTTGGACAAGTATGCATTGCACTTTGAGTCGCAGCACTTAACACTGGCCGAGGAGAGCTATAGCCTGCAAGATTTGGTAACCAATTCCCGGTCATGCGATGTGgtggaaattaaatttgaagaggatCCACCTGATGACCCGATTAAAGAAGAATTATCCAAAGGAAATTTGGTTGAGGTGCCGGCACTTCAGAGTATTTGTGACCGTGAAGCTAGTGACAATGAAGAGTTTCTAGATGAAGATAGATCATTGCTGGAAATTctgcatgaaagcaaaaaatcccACGAACAAAAGGTTACAAAGAAAAGGAGATGTGATAAATTACCAAAGCAGGAGGTTAATTCAAGTCTTGAGACATCAAGCCAACTGGTGGAGCTATCAATATCGTTGGCAGTAGATAATACCAATAATGAGCTggatatttcgaaaaatattagtgatgatgatggcaatggagatgatgataacgatgatgatgatgatgatgattggcTGGAGAAACGGGACAAAAAGGCGAAAACCAGGtCGGAGGAAAGCTCTAACGACTCAGATATTGAACTTCCACATCCCTGTCTGATATGCCAGCGATCATATCGTAGCAAACAGAGTTTAGAAAAACACAACCGTCTGGTACATAATCCCAATGGAGCGGCTGTTAAGAGAAAGCGAAAGAGAAGTAGCAAAAAACCAGCGGATGAATATAAATGCAATGAATGTGATAAAGTTTTTCGTTCAGAACGTGAAATGGGTGCCCATAGATTTCAACACACTGGCATTTTTTGTGATATCTGCGGCAAGACATTTACCCAAGTGGGAAATATGAGACGACATCGAATGCGTCATGATGGCATCAAAGCCCATAAATGCCGCGAAtgttctaaagatttttttaccaaaaaagaaTTACTATCGCATATGATTTGTCACACTGGTCTCATGCCGTGGATTTGTGAGATATGTGGAAAACGTTGTCGTGATCGTGGTGTCTTAACGGCCCACATGCGTCGACATACTGGCGAACGGCCGGCAAAATGTAATGTTTGCATGAAGAGTTTTTTCTCATTTCACGATTTGAATGTCCATGCCGTGGCTCATACCAACGAAAGGCCGTTTAAATGTGACATATGCTCGGCTACATTTCAACGAAAGAAAGCTTTACGTATCCATAAAAGAATACACACAGAAGCGCGTAAACACATTTGCCAGATATGTGGAAAAGCATTTGCGCAAGCGGGTAGTTTAAAAACGCACATGATTAGACATGGTACTGCCATGGAGAAAACTGAGAACGTCATTGCAAATAAAGAAATACAAGAATCTGCTGTAATTGTTGTTAAAAATGATGGTGCAAATGATGTGGCCACCATGTCCGCTGGTCTCTTAtCGAAGGCAAAGACCACCGAGCAGCGTTCTTGTGAAATCTGTCACCGCCAATATACATCGttgaaaaactacaacaaacacATGTATTATTCGCacaacattaaattatattcccGAAAAGTCAATTACAAATATCATTGTGATGGATGTGAGAAAGCCTTTAGGACTCCGCGTGATCTAAGGGCACACACATTGAAATGTAATCATAATGTGAAATCGGACTCCAATTACGGTGGGGAAGCGAAGCAAGAGGAGGTAGAGGAGGATAATTTTAATACAACAGAGGAGTTTCAAAATTCAATCGACAACGAAGCAGTTGTGCAGGATGGTGAAGAAAATCCCTTGGAAATGTTAAaccaaaatcctgaaaataataAAGAGGAAGAGGAGCAGTCAAAACCAACAGCTAAGACGGGCAAACATacgcaacaacaccaacaacaaaatgaattaTCCTGCCATATTTGCAACCGCAAATACACCACCataaaactacacaacaaaCATATGTTTGCAGCGCATCAAATTAAAATCCTATCGCGAAAAGTCAACTACAAACATAAATGTGACGAATGTGATCAAGTGTTTCGAATCGAACGTGATCTAAGGGCACACAAAGTGAAACATCAAAAGGAATTGGAAAATGCATCATCGATCATAACAATGCTGCCCAACAGTGAACACAAGGAGAGAAAAAGAGGCTTTAGGTCAGCTATGTCCACAACTGAAACAGTGCAAATGGAAGTCATGGGAATGATGCCAATGCCAAAGGATGATGGTGTGGCAAACAAACAAGTACATCATAACGACAATCAGTCTGCGGTGGAGGATAACGATGGAGCCGAAGAAGACACCGATTGGTTGGATGATAGCCTTGTGGAAAATGAACCGAATTTAGAAATAAGTGATAGTAAGGAAGTACTAAGCTGTCGCATCTGCCGGCGCACCTTCAAAGCTCTAAAATTTCTCAACAAACACATGTCGTTGAGGCATAAAATCAAAGTCCTATCCCGCAaagtgaactacaaatacaaatgtgATGAATGCGAACAAATGTTTCGAACCCAACGTGATCTCAAGGGCCACAAGGTGCGAGAACATTTGGGCATATCCTGCGATATCTGTGGCAAAATGTTTGCACAGGCTGGCAATATGCGGCGACATCGTGTACGCCACAGCGGCATTAAGGCATTCAAATGCAAAGAATGTCCCAAGGAATTTTATACCAGCAAAGAATTGAAATCCCATACCATTTGCCACACCGGAATATTACCATATATCTGTGAGATATGTGGTCGCAGGTGTCGTGATGGTGGTGATTTGTCGGCCCACATGCGTCGCCATACAGGTGAAAGACCGGCGAAATGTGATGTTTGTGGTAAACGATTTTTCTCAGTGCACGATTTGAATACCCACTCGGTTATGCACACAACAGAGCGGCCATTTTCCTGTGAAATATGTGGCTCAAGATTTCAGCTAAAGAAAACCTTGCGGGTCCATAAACTCATACATTTGCCACCGCAGTTTTCATGTAATATTTGTGACAAGACATTTGTCCAGTCGGGTCATCTAAGGATACACATGCGCCGGCATGGTAATCTTCAGGAAAAGACCAACAACAGCGAAGAATCGAAGAATGAATCGAACCCGGAGGAATTGTATGTTCCAACGGTGTTTGAAGGTTCACCGGACAATGTCGTCAATGTTATGCCAAATGCCCAAGGAGTTTAG
- Protein Sequence
- MLKAIGQLPTYENVKCGEIFCVSSPPAVFNVTCILCDQKISLDKYALHFESQHLTLAEESYSLQDLVTNSRSCDVVEIKFEEDPPDDPIKEELSKGNLVEVPALQSICDREASDNEEFLDEDRSLLEILHESKKSHEQKVTKKRRCDKLPKQEVNSSLETSSQLVELSISLAVDNTNNELDISKNISDDDGNGDDDNDDDDDDDWLEKRDKKAKTRSEESSNDSDIELPHPCLICQRSYRSKQSLEKHNRLVHNPNGAAVKRKRKRSSKKPADEYKCNECDKVFRSEREMGAHRFQHTGIFCDICGKTFTQVGNMRRHRMRHDGIKAHKCRECSKDFFTKKELLSHMICHTGLMPWICEICGKRCRDRGVLTAHMRRHTGERPAKCNVCMKSFFSFHDLNVHAVAHTNERPFKCDICSATFQRKKALRIHKRIHTEARKHICQICGKAFAQAGSLKTHMIRHGTAMEKTENVIANKEIQESAVIVVKNDGANDVATMSAGLLSKAKTTEQRSCEICHRQYTSLKNYNKHMYYSHNIKLYSRKVNYKYHCDGCEKAFRTPRDLRAHTLKCNHNVKSDSNYGGEAKQEEVEEDNFNTTEEFQNSIDNEAVVQDGEENPLEMLNQNPENNKEEEEQSKPTAKTGKHTQQHQQQNELSCHICNRKYTTIKLHNKHMFAAHQIKILSRKVNYKHKCDECDQVFRIERDLRAHKVKHQKELENASSIITMLPNSEHKERKRGFRSAMSTTETVQMEVMGMMPMPKDDGVANKQVHHNDNQSAVEDNDGAEEDTDWLDDSLVENEPNLEISDSKEVLSCRICRRTFKALKFLNKHMSLRHKIKVLSRKVNYKYKCDECEQMFRTQRDLKGHKVREHLGISCDICGKMFAQAGNMRRHRVRHSGIKAFKCKECPKEFYTSKELKSHTICHTGILPYICEICGRRCRDGGDLSAHMRRHTGERPAKCDVCGKRFFSVHDLNTHSVMHTTERPFSCEICGSRFQLKKTLRVHKLIHLPPQFSCNICDKTFVQSGHLRIHMRRHGNLQEKTNNSEESKNESNPEELYVPTVFEGSPDNVVNVMPNAQGV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -