Mdom002902.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Musca domestica
Gene Symbol
ZIPIC
Assembly
GCA_000371365.1
Location
Scaffold18839:178102-186976[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 27 0.23 11 6.4 5.3 1 23 242 265 242 265 0.98
2 27 0.74 37 4.8 2.9 2 23 422 444 421 444 0.94
3 27 0.26 13 6.2 3.4 3 23 453 474 451 474 0.95
4 27 0.0026 0.13 12.5 2.0 2 23 564 586 564 586 0.97
5 27 0.0019 0.093 12.9 3.8 2 23 593 615 592 615 0.95
6 27 0.4 20 5.6 7.5 1 23 635 657 635 658 0.95
7 27 0.00023 0.012 15.8 1.3 1 23 664 686 664 686 0.97
8 27 8.6e-06 0.00043 20.3 1.8 1 23 692 714 692 714 0.99
9 27 2.6e-07 1.3e-05 25.1 1.9 1 23 720 742 720 742 0.99
10 27 0.00031 0.015 15.4 0.4 2 22 749 769 749 772 0.90
11 27 0.017 0.82 9.9 0.3 2 23 960 981 959 981 0.80
12 27 3.5 1.7e+02 2.6 0.4 1 23 1008 1031 1008 1031 0.96
13 27 0.02 1 9.7 0.2 2 23 1141 1163 1141 1163 0.94
14 27 0.00023 0.011 15.8 1.6 3 23 1172 1193 1171 1193 0.95
15 27 0.0055 0.27 11.4 5.6 1 23 1216 1238 1216 1239 0.95
16 27 0.0037 0.18 12.0 0.7 1 23 1245 1267 1245 1267 0.93
17 27 2e-07 9.9e-06 25.4 0.8 1 23 1273 1295 1273 1295 0.99
18 27 2.9e-07 1.5e-05 24.9 1.4 1 23 1301 1323 1301 1323 0.99
19 27 9.1 4.5e+02 1.3 0.2 3 17 1413 1427 1412 1428 0.87
20 27 0.00027 0.014 15.5 0.3 2 23 1629 1651 1628 1651 0.93
21 27 3.7e-05 0.0018 18.3 3.7 2 23 1659 1681 1658 1681 0.97
22 27 0.00087 0.043 14.0 6.5 2 23 1701 1723 1700 1723 0.97
23 27 0.0084 0.42 10.9 1.3 1 23 1742 1764 1742 1764 0.95
24 27 0.0094 0.47 10.7 3.7 1 23 1770 1792 1770 1792 0.96
25 27 1.8e-07 8.7e-06 25.6 1.6 1 23 1798 1820 1798 1820 0.99
26 27 7e-07 3.5e-05 23.7 1.3 1 23 1826 1848 1826 1848 0.99
27 27 0.0034 0.17 12.1 1.7 1 22 1854 1875 1854 1878 0.91

Sequence Information

Coding Sequence
ATGGAACATGTTGAGGAGGCTTGCCGCGGCTGTTTAAAGAATTGTGTGAATGATTTGGTTAAAATATCAGACATAGCTGTATATTCCAAACCAAGGAAGAGATACATTGATGTACTGAAAGAGTTGGCGAAACTGAAGACATTTGGTGATCTGGAATGTAACATACCACAAAACTTGTGCTCAGAATGCTGTAGACAAGTATATCAAATGTATTTGTTTGTGAAACAAATACAGCGCACCAATCAAGAACTATCCCATATGTTGGATCTGGTAGATACTGGTGGCGGTCTTGATGTTATGTTCGGGCCCAATAAAGTAAAAATGGATCTTGATCAGGAAATATGCTCTAGCGGTGTAGAAGAACATTTCTTAGAAATAGATGTAAAAGAGACCGCCTCAATAGAAGGGCAACTACCAGTTGAATGTGAGAATGGGATCGAGCAAATTGCGGTGCCTTATGTGGATATATTGAAATCGAACTACGATAATCATGACAACGATGAAAGTGTTATTGAGGAGGAAGaggaaatattaaatgaaaaccacTGTGATAATAAATATGAAACTAAGAAAAATACCGATCAACATCTTATTGAACTCCATCAAGATGAACTAATAAGGGAAACAGAGACATACAATTGTAATTCGTGTAATTATTCTGCCAGGACATTGGCGGGTTTGCATTTTCACAAACGTTCTAAGCATGGCAGTGAAACAGATaaattcaaatgtaaattttgtacaTATACCAGCATAAAGAAGTTTGATTTATTTTCTCATACaaaaaaaTCACATCTTTCGAttataaaaattcttcgaaaacaaaatgatctggAAACGAATGCAAATGAATCAAATCTTGACTCGGACGTTCCGTCAAACAAATGTATGGAAGACATAATTCAAAGTCTATCCGCAACTCAAAATCAAATCGAAATGAGCACTGAATTCTGCTCCACCGACGATGAACAGTTCATTAGAGACATTCTCTGCATTAAAAGGCGTTCTCGAAAATCACATAAAACTGATAAAACTATGTCAGCTAAAACCCATCCACATTGCCAGGAAATATATCACTCATCTCATGTTGATAATAATGAATTGCTGAACTTTTACGAATCACATACAGCAATCATTTCGATACCTTCGGAaggaaatatttcccaaaacaaagagcaaataaaacaatacacaaatgatgaaaactcgacaaaacatcaaaGTAATCCCCATATGTTACCCACTAAAACCCAAAAAATGCTACAATGCCAACTCTGTGATTATACCACCAAAACATCTGCTGCATTACATTTTCATAAACGTTCCAAACATGGCACAGATGAGGACAAAATTAACTGTCATTTTTGTCCCTACATAGCCATTAGGAAATATGATTTGTTGCACCACATCATAAAGTGTCATTTGGCCATTGTTAAGTCGATCAAAAGGGAGATCTTGGAGAATACAAGTAGAGCTAAccatTTGAAGGATACAACCACAGAACCCGACATGATCTCTGAAGatgttatacaaaatttaatacacaaacacaaaaattcTGAGAGTAACGATAAAGCTATTACTGATGAAAGCTTGGAGGCATCTAGCGGCGATGAAACCACTATTCGACAAATCTTAAGAATGaaaaaaaGAGGAACCACTTCTGAGCTTACAAGTTCGCTGCCAAGGCGCTGTGAAGAATGCGGCAATATTTATAAGAATTCAAAGGCTTTACATACACACCGGCGTATGATGCATGTTGAACGTGACTATAGTCAGTGTCCTCATTGTGAGTGTAAATACAAAAGAGCCTACGATTTAAAACTACACATAAAAGCCAAGCATCTGGCAAAGAATTTAAAACCCAAAAACCGCGTTAGAAATGTGGTGCAGGATAAACGTTATATGTGCACCGAATGTTCCTATGTCTGTTCCACATTGACATGTTTAACAATTCACACATATCGTCATCATACCGGCGAAAAACCACATCAATGTGAATTTTGCCCAAAGGCATTTGTCGTAAAAGCTGATCTTAAGACGCATCGTTATATGCACACCGGTGAACGTCCATATAAGTGTCCAATTTGTGCTAAAGGTTTTCGTGATCGAAATCACATGGAAAGACATAGGCGAATACATCTTGATGTCAAGCCATATAGTTGCACTGAATGTGGAAAAGGTTTTACAAAAACATATAACCTAAAGGTACATCAACGAACGCACACAAAAGAACAGAGGCCAAGATGTCAGATTTGtagtaaatattttaaggatcaaGCGCAATTAAATGTTCATCAAATAAGTGAGGATCATCACGAAGAAGTTATACTCACTATGGAACAAAAAGCTAAAATGCCACAAGGACTTTGCATGATTTGTTGTGGTCAATTTCATCGCATGTACAAGTTTATTAACCAAATTAAAGAGTGCAATCACAAACTCATGGTCATGATAACTGATAATCAATTGGACTGTTTACAAGAAGATGTCATAGATATTCCAAGGGAAGATGCCGTAGAAAATATAGAACAATGTCGAGACACAATAAATACTAACAGAAATCAATGTGATAAAGGTGAAATCGACACAATAGATGAGCCTAACATATCGAAGGACCATGTTCGCACTATCCCAGAAGTAGCAAtctcaaataattataaaacaacAGTTGGCCGGCTACAGTATGAAGAGCACACAGAAATTCTGAATTTAAACCAATATAAACGTAGTACTTATAAAGACAACGTAGAAGCAGATGTCAGTAATTCTCAGGCAGAATTAAATTTCCATGATTTGAACTCCGAGAAAATGTGTGCCCGGTTTGACGGcaattctttaaaatgtttcaatttggATAAATCTCTGATAGACATATCTTGTCCACTCTGTGCAAAAGCATTCAAAAGACCCTACCTTCTAAAACATTTGCGCAAGCTACATGGTATAGATCAACCTAGCGCTTTTATGAGACAACACTTGGAAATCGCTACAAAAACCTCAAAGGATAGTTATAAACTTTTTGAGTGCCAGCAATGTGCTTATGTAGCCAAAAGCAAACCGGCCATTAACTACCACAATCGTACAAAACACCCTACCGAAGAGGATAAgttcaaatgtaaattttgttccTTCGAATCActgaaaaaattggatttggtAGAGCATATTAGGAATGAACATAGAATCGAATTTAAAGCTTTGAAACGGAATGTGAAACAGAGACAAGAAAATGGtaAATTTTCAGCTTGTTCTGAATCAGAGGATGATGTTGCAAATCTAGAAATAGCACCCAATGAACAAAATTCTCCCTATTCAAGTGAAAATGATGATGAGTTCATAAAAGATATGATAAATATCGAAAGAAAGCATTTAAAGTCAAATGTAATAGATGGTAGACCCATCAGTACGTTGGCAAGAACATGTGATGATTGCGGTAACGTTTATAAAGATTTTCCCTCGCTGTATGCTCACAAACGTTTTGTACACATCAGCGAGGATATGTACAGTGCATGTGTGCATTGTGGCAGAAAATATAAACGTAGCagagatttaaaaaatcatatattacAAATACATCCCACTGAAACGCACATAGAAGTTATTAAAGATCATACTGCGAGATCAGAAGATACGGCTAAACGTTTTATGTGTTCGCAATGTAACTATGCATCAACAACTACAACACATTTGAAACTTCATATACGACGCCATCATACTGGTGAAAAGCCATATGTTTGTGAAATTTGTGGTAATTCATTTTTAACATCATATGATTTGAAAAAACATAGTTATTTGCATACGGGAGAAAAACCTTACAAGTGTCCAATATGCCCGAAATCGTTTCGTGTTAGTTCGAAGCTAATAAAACATAAACGGGTGCATACCGGCGAGAGACCTTTTAAGTGTAACGAATGCGGAAAAGGATTTACCCAGGAATACAATTTATCAGTACATAAACGTACCCATCTAAAACAGCAGAAGACAAATCAATGTCTTCCAACttgtgtattatCTGAGCTTGATGGAGacgggaataaaaatattgggcaaaaaatGAGCATAATAAATAGAAATAACAAATGTCGAACATGTTTGAAATCCGGCACCAAATTGCAGTCCATTAGCACAAAGCCGAAAATGATGAAAGTTGATAAAACCTACATGGAATTAATAAATCACATAGCACAAGTTGAGtttgATACCGACGATGAACATAAAATGCCGCAAGGAATTTGTTCCATATGCAGCAAGAAGATACGTGACTCGTATACATTTATCAAGCAAGTGCGAAAATGCAATACAATATTCTTAAAGAGCACAATAAATATACCAGATGACAATCCTTTGGATAAATTGGAAGAAAGCTTTGCAACGGAAAATGTATTGCTGGACGAGTGCGATGACAAAAGTATTAAGGAAGAGGTTAATCCCTTTGATGACGAGGAAATGAATGCTCCCAAAAAGGAGGAGGTGGATTCAGATTCAAGTAGCTCCTTTTCGAATGACAATTTTGAGCCTATGCCACCAgatggccatgatgatggtgatgatacCGATACACAGGAGGAATTTATTAAGATTAGCGATACAACTACAAAGGTAAATGTTGTCACGGCTGCCCCTGGACCGCTGCCTTCCTCCACAGTGCCGGATGATGATGTGGCCATCAAGACGGAGGAAAGTGAACAAAAGGATGAGCAAGCCGCAGAATTATTTCCAGAATGTGTATTAAGTGAAAAAGTATTCTCCGATGATGATTCTCTTAGTGATTTGGACTCTGTTAAGGCTGAAGATGATCCAACATATGATCCTTTGGAGAGTAAGACAAGAAAACGAGCCCCTCGAAGCGAAACCCTCGATGAGGATAAAAACTTACCGGTACCATGTGAAGACTGCGATCGAGTTTTCCAAAATGCTAATCTCTTGAAAAGACACAAGAAAGACACACATTTACCGGATGAATTAAAGGTGCAATGTCCTCATTGTCCGGCCAAGTTTAGTAGACGTCACAACATGTACACACACATGAGAACGTTGCATAAAATCGAACCCGTAATAGAACAAAAAGCCAATCCGAAAAAGGAAAGGAACAGCGTTAAATGTGAGCACTGTCAAAAGAGTTATTGCAATAAGTATAAACTTATGGATCATATCAAACGTAAACATGGACCGGATAGTAATCAaccgaaaaaagagaaaataaaacaaccaGCTAAACGTTTCCTATGTGCCCTGTGTGGTTTCACGTGTAACAGTCAGCCCAATTTGGATGTCCACTATCGTAGGCATACCGGTGAGCGGCCATTTAAATGTGATCATTGTGATCGTCGTTTTTATCGCATGTACGATGTGCAAATGCATAATTTGAGTCACACGGGTGAGAGACCCTTTAAATGTACCGTGTGTGAGAAGGCATTCCGGAGATCGGGTAAACTGAAAATTCACATGAGAACCCATACCAACGAAAGACCCTACAAGTGTACAGAATGTGAGAAGGCATTTAAACAATCGAAAGATTTGACGGTGCATAGACGTATTCACACCGGTGAAAGGCCTTATAAATGTAATGTATGTGAGAGTACATTTATCCAGAGTAATTCATTGCGATTACATCAAACAAAGACTAAACATTCAAACGATCCGGTAAAtccaataaataataacaattcgGCGCCAGCAACGACAAATACTCTAATGAATAATGCCATGAACAACAATAGCGTTAGCAGTAGTTTGTTAAATAACACAAGTTCAACAAATACTGGAAATTTGTCACATAACACAAATAATAATCCTGCACCTCCTCCACCCATGCCCAATACCTCGGCCATTATTCATCCCAATATTCCTACAACAAATAATGCAATAAACAACACCGGCAACATTACCCACAACACCAATAGTAATTCTGGAGACACAAAATATCCCGAAATGCTTATgaataaaatgttgtaa
Protein Sequence
MEHVEEACRGCLKNCVNDLVKISDIAVYSKPRKRYIDVLKELAKLKTFGDLECNIPQNLCSECCRQVYQMYLFVKQIQRTNQELSHMLDLVDTGGGLDVMFGPNKVKMDLDQEICSSGVEEHFLEIDVKETASIEGQLPVECENGIEQIAVPYVDILKSNYDNHDNDESVIEEEEEILNENHCDNKYETKKNTDQHLIELHQDELIRETETYNCNSCNYSARTLAGLHFHKRSKHGSETDKFKCKFCTYTSIKKFDLFSHTKKSHLSIIKILRKQNDLETNANESNLDSDVPSNKCMEDIIQSLSATQNQIEMSTEFCSTDDEQFIRDILCIKRRSRKSHKTDKTMSAKTHPHCQEIYHSSHVDNNELLNFYESHTAIISIPSEGNISQNKEQIKQYTNDENSTKHQSNPHMLPTKTQKMLQCQLCDYTTKTSAALHFHKRSKHGTDEDKINCHFCPYIAIRKYDLLHHIIKCHLAIVKSIKREILENTSRANHLKDTTTEPDMISEDVIQNLIHKHKNSESNDKAITDESLEASSGDETTIRQILRMKKRGTTSELTSSLPRRCEECGNIYKNSKALHTHRRMMHVERDYSQCPHCECKYKRAYDLKLHIKAKHLAKNLKPKNRVRNVVQDKRYMCTECSYVCSTLTCLTIHTYRHHTGEKPHQCEFCPKAFVVKADLKTHRYMHTGERPYKCPICAKGFRDRNHMERHRRIHLDVKPYSCTECGKGFTKTYNLKVHQRTHTKEQRPRCQICSKYFKDQAQLNVHQISEDHHEEVILTMEQKAKMPQGLCMICCGQFHRMYKFINQIKECNHKLMVMITDNQLDCLQEDVIDIPREDAVENIEQCRDTINTNRNQCDKGEIDTIDEPNISKDHVRTIPEVAISNNYKTTVGRLQYEEHTEILNLNQYKRSTYKDNVEADVSNSQAELNFHDLNSEKMCARFDGNSLKCFNLDKSLIDISCPLCAKAFKRPYLLKHLRKLHGIDQPSAFMRQHLEIATKTSKDSYKLFECQQCAYVAKSKPAINYHNRTKHPTEEDKFKCKFCSFESLKKLDLVEHIRNEHRIEFKALKRNVKQRQENGKFSACSESEDDVANLEIAPNEQNSPYSSENDDEFIKDMINIERKHLKSNVIDGRPISTLARTCDDCGNVYKDFPSLYAHKRFVHISEDMYSACVHCGRKYKRSRDLKNHILQIHPTETHIEVIKDHTARSEDTAKRFMCSQCNYASTTTTHLKLHIRRHHTGEKPYVCEICGNSFLTSYDLKKHSYLHTGEKPYKCPICPKSFRVSSKLIKHKRVHTGERPFKCNECGKGFTQEYNLSVHKRTHLKQQKTNQCLPTCVLSELDGDGNKNIGQKMSIINRNNKCRTCLKSGTKLQSISTKPKMMKVDKTYMELINHIAQVEFDTDDEHKMPQGICSICSKKIRDSYTFIKQVRKCNTIFLKSTINIPDDNPLDKLEESFATENVLLDECDDKSIKEEVNPFDDEEMNAPKKEEVDSDSSSSFSNDNFEPMPPDGHDDGDDTDTQEEFIKISDTTTKVNVVTAAPGPLPSSTVPDDDVAIKTEESEQKDEQAAELFPECVLSEKVFSDDDSLSDLDSVKAEDDPTYDPLESKTRKRAPRSETLDEDKNLPVPCEDCDRVFQNANLLKRHKKDTHLPDELKVQCPHCPAKFSRRHNMYTHMRTLHKIEPVIEQKANPKKERNSVKCEHCQKSYCNKYKLMDHIKRKHGPDSNQPKKEKIKQPAKRFLCALCGFTCNSQPNLDVHYRRHTGERPFKCDHCDRRFYRMYDVQMHNLSHTGERPFKCTVCEKAFRRSGKLKIHMRTHTNERPYKCTECEKAFKQSKDLTVHRRIHTGERPYKCNVCESTFIQSNSLRLHQTKTKHSNDPVNPINNNNSAPATTNTLMNNAMNNNSVSSSLLNNTSSTNTGNLSHNTNNNPAPPPPMPNTSAIIHPNIPTTNNAINNTGNITHNTNSNSGDTKYPEMLMNKML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-