Basic Information

Gene Symbol
-
Assembly
GCA_947086495.1
Location
CAMTZB010000027.1:2397191-2419680[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.17 15 7.1 1.7 1 23 373 395 373 395 0.96
2 11 0.042 3.8 9.0 0.9 1 23 402 425 402 425 0.93
3 11 0.73 66 5.1 0.2 1 23 429 451 429 451 0.91
4 11 0.11 10 7.7 2.1 1 23 456 479 456 479 0.97
5 11 0.0052 0.47 11.9 0.7 1 23 483 506 483 506 0.95
6 11 2.7 2.5e+02 3.3 0.1 3 21 520 538 519 539 0.86
7 11 0.089 8 8.0 0.3 2 23 592 614 591 614 0.96
8 11 0.011 0.99 10.9 0.5 2 20 630 648 629 651 0.92
9 11 3.7e-06 0.00033 21.8 2.3 1 23 657 679 657 679 0.99
10 11 0.00027 0.025 15.9 2.8 1 23 686 708 686 708 0.98
11 11 4.3e-05 0.0039 18.4 2.2 1 23 714 737 714 737 0.95

Sequence Information

Coding Sequence
ATGAGGTGTTGTGTACAGAATTGTATGAGTGACACAAAAAGAACTACAAAAAGCAATGGAATCACATTCCATGTATTCCCAAAAGAAACAAACCTACGTAATGCTTGGATAGATGCTTTGGGGATAACAGCGTTTGAGTCACGAAACAGAAGCGCTGTATGCTCTGAACACTTCAGTCCGGATGCGTTCTATGAGACCAAATGTGGCTTGAGGAAAGTTAAGAACGGATTTGTTCCAGTCGCGAATGACGATTCAGAACAAGACTTAGATGCTCCAGCCACATATCGGGTGTGCAGGATATGCCTGATTATGAATGTCAGAATGTTCCATCTGACTGACAAAAAACTGCGCAAAATGTACGAACAGGTCACCGGCGTACCCATAAGTACAAATGATAAGATGCCCCTAACTCTCTGCTGGGAGTGCGTCGCGCGACTCTCGTCCGCGAACAGCTTCCGGAACAAAGCGTTGACATGCCAAAGGTTGTTGCTGAAAAAGTTGTTCGGCGACAGAACGATAACAATAAGGGATATAAAATCCATTAACAGAGCTAAAAATCAGTTAAAATCTAGTCTCTGTCAGAAAATATACGAAGCCAATGAATGCGACCTCGAATTGAAAGATGAGGAAATTAAAACGGAAATTAATGAATGCGACGAAGTTAACGATACTAACGATAATGTTAACGAAGTGAACGGTATAGATGAAGATTTTAACGATAACGAAATACAAGATAACGGTGTAGAAGATAACGAAGCGGATTTGAAATGCGAAGTTGAGATCAAAGATGAGACAACGAGTAACGAGATATACTTCGAGTGTCCTGTCTTTGATGATAGCGATAACGTGGCTTTAAGCGAGTCTTTTAAGAAGAAGAAGGTCAGAAAGAAGAAGATGAAGATAGTGAAGGAGTTGAAAGAAGTTAAAACGAAGAGGACGGCAGTGGATAGCAATCCTTCGAGCACTATGGACAAGTATAAAAAGTCCGATGTCAAACGGAGGAAAACCAACGACGGTTTGGACGAGTCGCTCTTTACTATTACCACTTTGACCTATGAGGAACAAATAGCGGAAATCGAGAAGAGGCAGGAGACAACTTTGTATAAGAACTCCGCCTTTAAATGTACGGTGTGTTATCGAGGTTTCCATGTGAGGGACAGATATGAGGCGCACGTGGTTAGACATAGTGAGCAAAGCGGCGCTTTCGAGTGCTTTATTTGCAAAACCAGACTGAAGACTGGGAGAGCGCTGCGTAAACATTTGACAGCTCAGCACACTGAAAAGTTCAGCTGCAAGGGATGTCCTTTCGCCACCAGGAACAGGGGCGTGGCACGGGAGCACGAGAAATGGCACGCCGGCACCAAATACCACTGTCCGCACTGTCCGAGCGAGTTCGACAAGGTGACTACGTACATGGGCCATATCCGAATAAAGCACGTGTCGGATTTCGTTTGTGAGCTGTGCGGGTATACATTTGTCAGCAGGAAGGGCATCGACGTGCACAAGAAGAAAAAGCACCGACTGGTGGAGAAGAACATCAGTCTAGACGGGCCCTTCTGCGACGTGTGCGACGTGAAGTTCGTATCGGAGGAGGCGCATGCGAGACACCTCAAGCTGTCCTCCAAGCACAGCAGCGACAACGACCCaaatcgCATACGCAATGATTCACAAAGCATGAACACGGAACGTAATGGACGGGTCATGAGGAAAATAGAGAGGCGACCCACCATCCACCCGCGGGCTAGCACGGCGGGCCCTGAAGGATTGCCGATCACTTGCGAACAGTGCGGCATGCAACTAAGGGATCTGCGGCTGTACGCGCAGCATTTCAGAAGAGCTCACCCGGACAAGAATCGAACCAAATACCCAGCTATGAAAACACCGTGTATGTGCGAGCAGTGCGGCAGGATATTTCAGAGCATGGCCCTCCTGAAGGACCACATGTGGGTCCACACCGGCGAGAAGCGGTTCAAGTGCAGCCTCTGCGACAAGAGCTTCACCCAGAAAACGAATCTGGTGTTCCACATGCGAGTTCACAGCGCCTCCCGCCCGAGCTACGAGTGCCCGCTGTGCGGGAAACACTTCGCCTTCTTCAACAACAGAAGGCGGCACATGTTTATCCACACTGGCCTAAAGCCGTTCAAATGTGACACTTGTGGCAAGTGCTTTACGACCGCGGGCGAACAACGGGCTCATATAGAACACGTGCATCTCAAGAAGCCGTGGCCGAAGAGAGCGCGCGCACGCAATGGCGAGGATGACTCGTGGCAAAAGTGCGCATTGCAGCACGTTGAGGATTAA
Protein Sequence
MRCCVQNCMSDTKRTTKSNGITFHVFPKETNLRNAWIDALGITAFESRNRSAVCSEHFSPDAFYETKCGLRKVKNGFVPVANDDSEQDLDAPATYRVCRICLIMNVRMFHLTDKKLRKMYEQVTGVPISTNDKMPLTLCWECVARLSSANSFRNKALTCQRLLLKKLFGDRTITIRDIKSINRAKNQLKSSLCQKIYEANECDLELKDEEIKTEINECDEVNDTNDNVNEVNGIDEDFNDNEIQDNGVEDNEADLKCEVEIKDETTSNEIYFECPVFDDSDNVALSESFKKKKVRKKKMKIVKELKEVKTKRTAVDSNPSSTMDKYKKSDVKRRKTNDGLDESLFTITTLTYEEQIAEIEKRQETTLYKNSAFKCTVCYRGFHVRDRYEAHVVRHSEQSGAFECFICKTRLKTGRALRKHLTAQHTEKFSCKGCPFATRNRGVAREHEKWHAGTKYHCPHCPSEFDKVTTYMGHIRIKHVSDFVCELCGYTFVSRKGIDVHKKKKHRLVEKNISLDGPFCDVCDVKFVSEEAHARHLKLSSKHSSDNDPNRIRNDSQSMNTERNGRVMRKIERRPTIHPRASTAGPEGLPITCEQCGMQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGRIFQSMALLKDHMWVHTGEKRFKCSLCDKSFTQKTNLVFHMRVHSASRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTAGEQRAHIEHVHLKKPWPKRARARNGEDDSWQKCALQHVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2