Basic Information

Gene Symbol
-
Assembly
GCA_947086495.1
Location
CAMTZB010000002.1:2891271-2895648[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00017 0.015 16.6 1.4 2 23 162 183 161 183 0.97
2 9 0.00016 0.014 16.7 0.4 2 23 191 213 190 213 0.90
3 9 0.00029 0.026 15.8 1.4 2 23 222 243 221 243 0.96
4 9 3.1e-05 0.0028 18.9 0.5 1 23 249 271 249 271 0.98
5 9 6.4e-05 0.0058 17.9 6.2 1 23 279 302 279 302 0.97
6 9 1.2e-05 0.0011 20.2 0.8 1 23 307 329 307 329 0.98
7 9 3.8e-06 0.00034 21.8 2.6 1 23 336 358 336 358 0.99
8 9 0.00012 0.011 17.1 2.7 1 23 364 386 364 386 0.99
9 9 1.4e-06 0.00013 23.1 2.4 1 23 392 414 392 414 0.99

Sequence Information

Coding Sequence
atgaccgattttaataaactCTGTCGTGCATGTCTTATCGCAATAGAtaccttaaaatataatttatttgaaaatgtttcacccgatatttatttgttttgtacTACTATAAAGGTGATGGAAAGTGAAAATTTACCAAAATCTCTATGTGACATCTGCTATGGCCTATTATCCAAATTTTCAGAATTTAAAAAGACTTGCTTACAATCACAGAAAACTTTACTGAAATTTAATACTGACATATCAGAAAACAAAGAGCAAGAATGGAAAAATAATGAACCTTGTAATGTAGATTTACAGAAAGACATATTGAACAAGTTTGAGGAGGAATATGAATGTGGTGTGACAGTCAAAGTTGAAGATTCTGAAAATAATTGTGAAAATGattTTGATGCAGCAGATGTCATCAGTGAATTAaatgtaacatttaaaaagaataaaccTCTTAAAAAACTTAAAAGATTAAAGCGAAGGAAAAAGATAAAATGTGAGTTGTGtagcaaaagttttatttcccATGAAAAATTGGAAGTACACAAAATAACACATGAAACTAAAgttAATTCCCTTAAATGTACACCGTGCAACAAAACATTTATCACCTGGAGTGGTCTGAGGAGGCATAATGCGAGCTGGCATATGCGAGTCAACCTGGCCACCCTCACGTGCCGCTATTGTGGTAAAATAACCAAGAGTCGAGAGACCTTGAGGACTCATGAAAAACTGCATGTAGACCGTAACCTTTTTATATGTAACGTTTGCGGTCAGGGCTGTACTACGAGTAGTGTTTTAAAGGCCCATCTCGAGACCCACATTGAAAATAGAGAACGCCATTACACATGCGAACATTGTGGTAAAAAGTTCTACACTAATAAAACTCTAGTATCGCACGTACAGAGGTGTCATACAGGCAAACGGTATATATGCCAAATATGCAATTTTCCCTTCACAGAGAAGTATAATTTGGGCAAACATATGCTCAAACATGATggcaaagttttaatttttaaatgtgaaaTATGTGATAAGTCGTACAAATCGCGAACATCATACATAGAACATAAAAGAACACATTCCGGCGAACGTCCTTATGTGTGTAGTTTTTGTTCTAAGAGTTTTATATCTAAAAGGAGGTTGACAGAACATAACCGCACACATACTGGTGAGAAACCGTACAAATGTAATGTTTGTGACCATAGTTTTGCGCAGAGAGGGACTTTAATGAGGCATAAAAGAGTGCATGATCGTGGTCCAATATTAAGTTAA
Protein Sequence
MTDFNKLCRACLIAIDTLKYNLFENVSPDIYLFCTTIKVMESENLPKSLCDICYGLLSKFSEFKKTCLQSQKTLLKFNTDISENKEQEWKNNEPCNVDLQKDILNKFEEEYECGVTVKVEDSENNCENDFDAADVISELNVTFKKNKPLKKLKRLKRRKKIKCELCSKSFISHEKLEVHKITHETKVNSLKCTPCNKTFITWSGLRRHNASWHMRVNLATLTCRYCGKITKSRETLRTHEKLHVDRNLFICNVCGQGCTTSSVLKAHLETHIENRERHYTCEHCGKKFYTNKTLVSHVQRCHTGKRYICQICNFPFTEKYNLGKHMLKHDGKVLIFKCEICDKSYKSRTSYIEHKRTHSGERPYVCSFCSKSFISKRRLTEHNRTHTGEKPYKCNVCDHSFAQRGTLMRHKRVHDRGPILS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-