Mlae032005.1
Basic Information
- Insect
- Monopis laevigella
- Gene Symbol
- znf423
- Assembly
- GCA_947458855.1
- Location
- OX375846.1:2873293-2878675[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 4.2 3.7e+02 3.0 1.7 1 23 24 47 24 47 0.92 2 18 0.14 12 7.7 3.5 2 23 73 95 72 95 0.94 3 18 0.0017 0.15 13.7 0.1 2 23 118 139 117 139 0.95 4 18 0.00022 0.019 16.5 0.5 1 23 143 166 143 166 0.98 5 18 0.009 0.78 11.4 2.4 2 23 170 192 169 192 0.96 6 18 0.051 4.4 9.0 1.5 3 23 200 221 199 221 0.90 7 18 0.011 0.93 11.2 0.3 2 23 229 251 228 251 0.96 8 18 2.5e-05 0.0022 19.4 1.4 2 23 258 279 257 279 0.97 9 18 0.00043 0.037 15.6 0.8 1 21 285 305 285 306 0.93 10 18 0.71 62 5.4 5.6 1 23 356 379 356 379 0.95 11 18 1.9 1.6e+02 4.1 0.1 3 23 405 426 404 426 0.93 12 18 0.0026 0.23 13.1 1.1 2 23 449 470 448 470 0.97 13 18 0.004 0.34 12.5 0.7 2 23 475 497 474 497 0.94 14 18 1.3 1.1e+02 4.6 1.0 1 16 500 515 500 518 0.79 15 18 1.8 1.6e+02 4.2 0.6 1 10 533 542 533 546 0.93 16 18 0.083 7.2 8.4 5.1 1 23 563 586 563 586 0.96 17 18 0.0022 0.19 13.3 3.1 1 23 592 614 592 614 0.97 18 18 0.00025 0.021 16.3 2.4 1 23 620 643 620 643 0.97
Sequence Information
- Coding Sequence
- ATGCTAAAAGAAAATACCATTAAACTAATTAATAATTCTAATATCATTATTTTTGGAGGAACGAGGAAGTTCAAATGTCTCCTATGTCGCGCTAACTTCGCGTGCATATCCAATCTCCGAGTCCACAGTGTGACCAAACACAGAGCCGACGAGATCGCCAACAAGATTTTAGCACAAAGGCTATCTAGTTATTTCCAAACAGACATAACTAACTTAAAATGCTCCCAGTGTTCTTTGCCATGTGAAACTTTGGAAGAATTAAAAAAACATTTAGTAAAGTGTCACGATGTAAAATTATTTTCAATTGATTCGATGTTAATTCCGTTTCGATTCTCTAAAGACAACATATTGCGATGTGTGATATGTGAGGAAGTATTTGAGAATTTCGCTAAATTATCTCGACACATGACGGCACATTACGGCAACTTTGTATGCCAGACTTGCGGCACGGCTTACTACGACAACAATCGCCTACAAATTCACATTAAAACTAATCACAGGGCTGTTAAATGCAGCATATGTAATATGAAGTTTTCTACTACACAGGAAAAGTTTAAACATAGAAGAAACGTTCATAAAATTATAGAAAAGAGGCACTGTACTTGTTGTCCTGCGACATTTCCTAATGCTTATAAATTGCTCAGGCATATGATAGAGGAGCACGGCAAACAAAAACCAGAACTAACTTGTCCGTTTTGTGATCAAAAGTTTATTTTAAAAGGAGCCCGGTCAACTCACATCAAGACCGTTCACCAGGGAGTCAGGACCAAGTCCTGCGACATATGTTCTATGAAATTCTATCGCAACTCAGATTTGATTCGACATCAAACGACTCACGATTCGGAGAAAAAATATTTGTGTGTTATTTGTCAGACTAAGTTTAAAAGTAAAGATTCTTTGAGTAGACATTTGAAGAATAAATTACGATGCAAAGTGGAAGATAAAGGGAACAAAGATTGGAAAAAAATAGTGGAACGTCGAGGTAATGGGCCGGTATTACGAGAAAACTCCCTAAAGCTCCTCGCCAACTCCACCATCTGCGTGTTCCAGTGGAACAAGAGTCGCTATCGCTGCTTCTGCTGCCAAAAGCCATTCCCCGACATGACAACGCTACGCCACCACACAAACAACTCTCACACGTTAAAAAACATTGAAAAAATTATAATATTACAACAAAACAAGTTGGTCAAAGTGGAGGTATCTTCCATATTGTGCAAGCTGTGCTCCGAGCCAGCGGACAACTTGTTACAGTTAAAAAAGCATTTAATAGAAATGCATAGTTTGGACTTCGGACTCACTACGGACGACTTGCTAGTTCCATTCAAACTGGACACAGACAACCTCCAATGCCAGCTGTGTTACGAGTCCTTCAGGCTGTTTCGCTTGTTGAACATTCACATGAACAAGCACTACCAGAAGCAAGTGTGCCACATATGCGGCGCGGGCTTTTCTAATCTAGTATTTTTAAATTTACACAAATCAAGATCTCATAGGCCACATTTTTGTAAGCAATGTGGTGTGGAATTCTCTAGTCGTTTGGAGAAGAGAGACCACGACGTGTCTATGCATAACTTGAGGATAGAGAGAAAATTGAGATTTCCTTGTCCTTACTGCAAGGAGAGGTTCCTACACGAGAACGTGAGGGTGGAGCATTTGGTGGACCGGCACGGCCTCACGCGGCCAGAACACAAATGCACAATGTGTAGCAAGATATACATAACCAAAAGTCTGTGTAACACGCATATTAAAAACGTTCACCTAAAAGAGAAGAACCATGAATGCAATCTTTGTAATATGCGGTTTTATACAAAGTCAGACGCGAATAGGCATAAAGTCACTCATACGGGGGAAAAAAATTTTTCATGTACATTCTGCAATAATCTATTTGCTACAAAAGATTCCTTAAGACGCCATATAAAAAGAACTCATGTTAATTTGTAA
- Protein Sequence
- MLKENTIKLINNSNIIIFGGTRKFKCLLCRANFACISNLRVHSVTKHRADEIANKILAQRLSSYFQTDITNLKCSQCSLPCETLEELKKHLVKCHDVKLFSIDSMLIPFRFSKDNILRCVICEEVFENFAKLSRHMTAHYGNFVCQTCGTAYYDNNRLQIHIKTNHRAVKCSICNMKFSTTQEKFKHRRNVHKIIEKRHCTCCPATFPNAYKLLRHMIEEHGKQKPELTCPFCDQKFILKGARSTHIKTVHQGVRTKSCDICSMKFYRNSDLIRHQTTHDSEKKYLCVICQTKFKSKDSLSRHLKNKLRCKVEDKGNKDWKKIVERRGNGPVLRENSLKLLANSTICVFQWNKSRYRCFCCQKPFPDMTTLRHHTNNSHTLKNIEKIIILQQNKLVKVEVSSILCKLCSEPADNLLQLKKHLIEMHSLDFGLTTDDLLVPFKLDTDNLQCQLCYESFRLFRLLNIHMNKHYQKQVCHICGAGFSNLVFLNLHKSRSHRPHFCKQCGVEFSSRLEKRDHDVSMHNLRIERKLRFPCPYCKERFLHENVRVEHLVDRHGLTRPEHKCTMCSKIYITKSLCNTHIKNVHLKEKNHECNLCNMRFYTKSDANRHKVTHTGEKNFSCTFCNNLFATKDSLRRHIKRTHVNL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -