Basic Information

Insect: Monomorium pharaonis
Gene Symbol: zfh1
Assembly: GCA_013373865.1
Location: CM023795.1:4987667-4994371[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.19 31 6.1 1.5 2 23 94 116 94 116 0.91

2 7 2e-05 0.0033 18.6 0.6 2 23 135 156 134 156 0.97

3 7 4.8e-06 0.00078 20.5 7.8 1 23 165 187 165 187 0.99

4 7 9.7e-06 0.0016 19.6 1.3 1 20 193 212 193 214 0.96

5 7 0.00053 0.086 14.1 5.5 1 23 659 681 659 681 0.94

6 7 6.1e-05 0.0099 17.1 7.1 1 23 687 709 687 709 0.98

7 7 0.0013 0.21 12.9 4.3 1 21 715 735 715 736 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.19	31	6.1	1.5	2	23	94	116	94	116	0.91
2	7	2e-05	0.0033	18.6	0.6	2	23	135	156	134	156	0.97
3	7	4.8e-06	0.00078	20.5	7.8	1	23	165	187	165	187	0.99
4	7	9.7e-06	0.0016	19.6	1.3	1	20	193	212	193	214	0.96
5	7	0.00053	0.086	14.1	5.5	1	23	659	681	659	681	0.94
6	7	6.1e-05	0.0099	17.1	7.1	1	23	687	709	687	709	0.98
7	7	0.0013	0.21	12.9	4.3	1	21	715	735	715	736	0.96

Sequence Information

Coding Sequence: ATGGCGCGCTGCCACGGCGCTGAGGTGAGATGTAAAAACCGTGCCACGTGTGCGCGTGTTACAGGCCGTAGCGAGGACGACGCAGGTGTCGTGGATACGGAGGTGGGCGGAGGTTGTGGCGCGGGTGGTGCGCCAACCGCAGGAGGTGGAAGTGTTGCCGGTTGCGATGGAGGTGGTGGCGTCGGCAGCGGCGGTACGTGCGGGGGGGTGGGCGGTGGTGGCGACGGCGAGGGCGGATCATCCGcgaagcagcagcagcagcagcagcagggtGGCGAAAGGTGCCCTCAGTGCGGCATCCACTGTCGGGACGTCCGTGTCCTGCAGCTTCACCTCGAGGACACGCACAAAACGTCCTGTACCATCGACAAGCACGATCTCAACGCCCAGTTCTCCCAAGTGTCCTGTAAGGTGTGTAGTAAGACCTTTGCCAACGTCTACCGACTGCAGAGGCACATGATTAGCCATGATGAAAGTGCTGTTCTACGAAAGTTTAAATGTCCTCACTGCGAGAAGGCCTTCAAGTTTAAGCATCACCTTAAgGAACACCTGCGAATTCACAGCGGTGAAAAGCCATTCCAATGTAACAATTGCGGCAAGCGTTTCTCTCATTCTGGATCGTATTCGAGCCACATGACGGCGAAGAAGTGCTTGATAATGAATCTGAAAAAGTCGAGGCAGAATACTATAAGCAATGTCGATCGAGGGCAGAAAAAGATGCATCAGGCGTTATCGGGACGACGTGACGTCGATCTGCTGACGGCcaacaataatacatttttgccGATCCTGCCGAAGTTGTCACCTTCGGAATATCAGGAGATACAAAGAGAGGGAAcagGTATTTATGACATGCCAACTCTGCTGCCTCACATGATGGGATTCGGAAATTACTTCCTGCAGTCTTCGATAAGTAAGCTGCTGAACCAATGGCACGCTAAGCGTACCTTCGATCACATTACCGAGCAATTTGAGACGCATCGGGAAGTGATGAGTCCATCGACAGCGGACTCAGAGGGAACGGAGGGCACTGAGGGCAAGGAGTCTCCCGCGCCAGTAGACCCGTTGCAGGGCCTCGATGCGGTCCGACGAATACTGGAGACTGTAAACACATCCGTGACGAAGCAGCTGCTTGAAGCGAATGTACGGAAGCTATCCACGTCTCCGGCCACTATGAAACGAGAGTTGGAAGAGGATTACCAGGATCAAGATAGCGAAATGTCTAGTGAAATGACGCATTGTCCGGACTGGAGCGGAGCGGACCAATACGACTCGCAAAGTGAAGGTTTAGCCGCAAAGCTTGAGAATGTCAATCAACCGACATCGAGATCAGCCAAGAGAAAAGCAGAGGACAGTTCCGAAGCAGATTCGGAAGATGAAGATGAGGGCAACCAACCTCACAATGACAACGGTAAAAGAGTCAGAGCTAGGTCGCTCATAGACGATGAACAGCTTGCTGTTCTGAAAGGTTATTACGCCATCAATCCACGACCTAAGAAGGAAGAGATCATAATGATTGCCGATTACATCCATTTTCCTACTCGTGTCGTACAGGTTTGGTTTCAAAATTCTCGTGCCAGGGATCGAAGGGAATCGAAGATGCCACCAGCCTTAGTTCCTCTAACACCTCCAGTAAATCCACCTATTACTGAACAGCCCTTGGATTTGTCGAAGAAAGAAGCAGTTGTTATATTGGCGACCAAAGAAAATGATACAGCGAATAGAAACACCTCGTCTCCGGGCGAACGGAAGGATAATACTGCAACTCTAGCTGTCGACAATGATGATCTCGAGGATTTGCCTTTGGTCATAGACGAAGAGACTCCCGCTACTGATCCTGTTGAGAATAAGCGTACACCTCCCAGTGGAGAGATAATTACaaagaatcaaAATCAAGCGAACGTAAAGGGCGAGAGCGAAGCTGCATTACAATCGGAAATAACACCTACGGCAACAGAAAATGAGCAGGGTCTTTATTTCTGTGATCGGTGTGAGAAAACATTTTCGAAACATAGTTCCCTCACGAGACACAAGTATGAACATTCCGGGCAAAGGCCCTACAAATGTGTGGAGTGTCCAAGAGCGTTCAAGCACAAGCATCATCTGACTGAACACAAGCGGCTGCACAGCGGCGAAAAGCCCTTCCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTACAGCCAACACATGAATCACCGTTATTCTTATTGCAAGCCCTACAGAGAATAG
Protein Sequence: MARCHGAEVRCKNRATCARVTGRSEDDAGVVDTEVGGGCGAGGAPTAGGGSVAGCDGGGGVGSGGTCGGVGGGGDGEGGSSAKQQQQQQQGGERCPQCGIHCRDVRVLQLHLEDTHKTSCTIDKHDLNAQFSQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTAKKCLIMNLKKSRQNTISNVDRGQKKMHQALSGRRDVDLLTANNNTFLPILPKLSPSEYQEIQREGTGIYDMPTLLPHMMGFGNYFLQSSISKLLNQWHAKRTFDHITEQFETHREVMSPSTADSEGTEGTEGKESPAPVDPLQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKRELEEDYQDQDSEMSSEMTHCPDWSGADQYDSQSEGLAAKLENVNQPTSRSAKRKAEDSSEADSEDEDEGNQPHNDNGKRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIADYIHFPTRVVQVWFQNSRARDRRESKMPPALVPLTPPVNPPITEQPLDLSKKEAVVILATKENDTANRNTSSPGERKDNTATLAVDNDDLEDLPLVIDEETPATDPVENKRTPPSGEIITKNQNQANVKGESEAALQSEITPTATENEQGLYFCDRCEKTFSKHSSLTRHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01421778;
90% Identity: iTF_00128072;
80% Identity: iTF_01015701;