Basic Information

Insect: Monomorium pharaonis
Gene Symbol: ham
Assembly: GCA_013373865.1
Location: CM023795.1:9183372-9266708[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0092 1.5 10.2 0.7 2 23 306 328 305 328 0.95

2 9 0.51 82 4.7 0.1 1 23 335 358 335 358 0.93

3 9 1.1e-05 0.0018 19.4 1.2 1 23 364 391 364 392 0.93

4 9 4.3e-06 0.0007 20.7 2.6 1 23 398 420 398 420 0.95

5 9 2.7e-05 0.0043 18.2 5.0 1 23 426 448 426 448 0.99

6 9 0.00052 0.085 14.1 0.7 2 21 456 475 455 476 0.95

7 9 6.2e-09 1e-06 29.6 1.2 1 23 833 855 833 855 0.99

8 9 3.3e-07 5.3e-05 24.2 1.7 1 23 861 884 861 884 0.97

9 9 9.2e-06 0.0015 19.6 3.4 1 23 890 912 890 912 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0092	1.5	10.2	0.7	2	23	306	328	305	328	0.95
2	9	0.51	82	4.7	0.1	1	23	335	358	335	358	0.93
3	9	1.1e-05	0.0018	19.4	1.2	1	23	364	391	364	392	0.93
4	9	4.3e-06	0.0007	20.7	2.6	1	23	398	420	398	420	0.95
5	9	2.7e-05	0.0043	18.2	5.0	1	23	426	448	426	448	0.99
6	9	0.00052	0.085	14.1	0.7	2	21	456	475	455	476	0.95
7	9	6.2e-09	1e-06	29.6	1.2	1	23	833	855	833	855	0.99
8	9	3.3e-07	5.3e-05	24.2	1.7	1	23	861	884	861	884	0.97
9	9	9.2e-06	0.0015	19.6	3.4	1	23	890	912	890	912	0.99

Sequence Information

Coding Sequence: ATGAGATCCAAGCCGGTGGCGAGAAGACTAGCACAGGGAAGCAGCGACGAAGGCGAGTCGACGTCGGGCGCGACTGGCGGGGGTGGAGGTAGCGAAAACGCAGAAATGGAGGAGAACGGATCGACTCGTAcgagcagcaacagcagcagcaacaacaatcCCTACAGGGATCTAAGTCAGGCCGGTGGCGAAATTCGGCAGGATTACAATCTGCAATCGCGGACTGTTTATCAGGAGCGCTTATTCTCATCGGGGATGGAACTGCGACAGCGGAAATTCACGAAGGAACAACCGTCGCTGTCTTCTAGGGACGAGGAGATAAAATCTTGTTGGGACTACGGCGAGAAGAACACGCGGAAGGAGTACTCGAGGTCGCGGGACTACAGCAATACGGAATACCAGGATGCGATAAAGCAGGAGCCCAAGGATCACTCGAGTCGCGAGTGGGTGTCACCGGTTTCGGAGGTCGAGATCGGCGGTTCGGCACCCGGGGGCCCGTACGTTCGTGCACGCAAAGACATCCCTCGTGGCACGAGATTCGGTCCGTTCCACGGCAAATGGGCGAGCGAGCCTTTCAACCCCCGTTACGCGTGGGAGGTACGCATAGCGGGGAGCGGAGTGAGAGGCTGGTTTGACGCGTCTCACGAGACGAACAACTGGCTCAAATATATTCGAAGTACTCCTAGCTCACATGCGGTTAACATGCGCCACGTACTCATCGGCGGTCAGATGATGTATGAAACTGTTCGCGACATTGCAACGGGTGAAGAGCTACTTTTGGGTCTTCGGGAGCCGCTTCAGCTGCAGGACATGCTGGGTGAAAATATAACCGAGGACAGAAGCGATCGTGAAACTGCCTCTCAGCACAGTGGAACTGTCGATGAGGATAAGGAGGACGAGGAGGAAGGAGAAACGAGGTGCACTGTCTGCGACAAGCCATTCCAAGATATCGAGCTatTGGATAGCCACCTGGTGACTTGTCATAGATATCCAGCGGAACAACATCGTTGCGACAGCTGTCCTCGTGCTTACGCCTGGCGGCCGCTTCTGGTGCGACATCGTGCCATCGTCCACGGTGACCTTCGAAATTATCCCTGTGAAAATTGCCCGAAGTCGAACATCCGGCAGGTCTTCACGGACCCATCAAACCTACAACGCCATATCAGAACGCATCACGTGGGCGCGAGGAGCCACGCTTGCACGGAGTGCGGTAAGACCTTCGCGACCAGTTCCGGCCTGAAACAGCACACTCACATCCACAGCAGCGTGAAACCCTTCCAGTGCGAGGTCTGTTTTAAGGCGTACACCCAGTTCTCCAATTTATGCCGACACAAGCGCATGCACGCCGACTGCCGCATGCAGATCAAGTGCGTTAAATGCGGACAATCCTTCAGCACGGTGACATCGTTATCGAAACATAAGCGATTTTGCGACTCCACGACCCCGACCGGTCCGCCTGGTACGATGCCTCAATTACCGACGCCAGCAACGAGCCCCTTTCTGGTATACCCACGACCTCCTGTGAGCCTACCAGGCGGTTTGCCTTTTTATCCACCTAGTTTAATGGGCCCTTATCCGGGACTTTTTCCGAACGCCCCGAATTTTCTGAACACGCCTCTGCTTTTCCCGCCGAAAATCGAGGAGGCCGAGAAAAGGAGCGACAGTCCCAAAAAGGAACGTTTTACTCCTCCACGAGTATTATCACATCACAATAAGGTTTCTCCTTCCACGGCAGAGGAAGCAACCTCTACATTCAGGCCATCTCCGGCTAGACCTCCCGTTCAACCGACACCGGAGAGTGACGACGATCTTTCGAAGAGAAAAGAAGCAGCCAGAAGCAATGAACGAAAAATGGAAACCGAAAGCACTTCGAAGGAGGAGACGACCGAGCAACCGTTGGATCTAAGGGTGCAGACTAAGAAGCAGGACACCATTTCAAAAGCCGCGGACAGGAAAAGCCGTACTCCGTCGCCAGCGCCAGTACCAATGGAGGGGACACCTGCACCTCCTGATCCCCCGAAACCGGAAGAAGATATTGCCGCTCCGCCACCGATGGAGCTCGAGTCTAAGGACATTCAAGGGAGTAGTCCTCACTTGAGAACAAGCCTGTCAATCGAACAACCACCGACCAATACACCGCCGCATATGGCTTATCCCAGACCGATACATCCAATGTTTCTCGAAACGATGTATCGTAGTCCTGCGGGAGCCTTCCCGGGCTTTCCCAGCGCACCACCACCTCCAAGTGGAGCTACCCCAGAATCTCGGCTGATACCTACGCTTCCACCCTTCGCTCCACCGCGCGGGCTTCCTTTTTTAGGCTCGCTTATGAACGGGCTCAGCGGCGCTAGGCCAGGAGGAGGATTTGATCTGCTTGCCCGTCCGCCGCTGAGCGCGTTCCCTGGTGTCAAGCCGTTTCAGGAAGCCGTAATGGCGCCCCAtcatcaccatcatcatcaccatcatcatcaCGTCCATGGCAAGATGAAGGATCGGTATTCCTGTAAGTTCTGCGGCAAAGTGTTCCCCCGCTCGGCAAATTTAACGAGACACCTGAGGACTCATACGGGCGAGCAGCCGTACAAGTGTAAGTACTGCGAAAGGTCTTTCAGCATCTCGAGCAACCTGCAGAGACATGTGAGGAATATTCACGATAAGCAGCGGCCGTTCAAGTGTCCGCTTTGCGAAAGGTGCTTCGGGCAGCAGACCAATCTGGACAGACATTTGAAGAAGCACGAGGCTGACGACGGTAGCGGAGTGGTGTCGGTGGCCGACTCGCCTGGAAGCAGTAACGAGAACGAGCGGGAGGACACCTACTTCGACGAGATCAGGTCCTTTATGGGCAAGGTTACTTACAGCGGTGAGAGCGGTTACGGACTGCCGCACCCAGCTTATATTCCCAATCGTCTGCACGAGATGAACGAATCCAAAATGGAGGTTGAATatgacgaggacgaggacagTGAGGAGGGTGCATCTCCTTTGGAAGAGACGGATGGACTGTCGCCGATCGAGGCCAAGGAATCTCCGTCGCCGTCGCAGTATGACCTGAAACTGAGGGAGAAGCAAGAGCTGCTCAATAATAATACCGCAGAGCCGGTGATCGAGATTTCGACATAG
Protein Sequence: MRSKPVARRLAQGSSDEGESTSGATGGGGGSENAEMEENGSTRTSSNSSSNNNPYRDLSQAGGEIRQDYNLQSRTVYQERLFSSGMELRQRKFTKEQPSLSSRDEEIKSCWDYGEKNTRKEYSRSRDYSNTEYQDAIKQEPKDHSSREWVSPVSEVEIGGSAPGGPYVRARKDIPRGTRFGPFHGKWASEPFNPRYAWEVRIAGSGVRGWFDASHETNNWLKYIRSTPSSHAVNMRHVLIGGQMMYETVRDIATGEELLLGLREPLQLQDMLGENITEDRSDRETASQHSGTVDEDKEDEEEGETRCTVCDKPFQDIELLDSHLVTCHRYPAEQHRCDSCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSNIRQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTTPTGPPGTMPQLPTPATSPFLVYPRPPVSLPGGLPFYPPSLMGPYPGLFPNAPNFLNTPLLFPPKIEEAEKRSDSPKKERFTPPRVLSHHNKVSPSTAEEATSTFRPSPARPPVQPTPESDDDLSKRKEAARSNERKMETESTSKEETTEQPLDLRVQTKKQDTISKAADRKSRTPSPAPVPMEGTPAPPDPPKPEEDIAAPPPMELESKDIQGSSPHLRTSLSIEQPPTNTPPHMAYPRPIHPMFLETMYRSPAGAFPGFPSAPPPPSGATPESRLIPTLPPFAPPRGLPFLGSLMNGLSGARPGGGFDLLARPPLSAFPGVKPFQEAVMAPHHHHHHHHHHHVHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYSGESGYGLPHPAYIPNRLHEMNESKMEVEYDEDEDSEEGASPLEETDGLSPIEAKESPSPSQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01407591;
90% Identity: iTF_01261975;
80% Identity: -