Basic Information

Insect: Monochamus alternatus
Gene Symbol: zfh1
Assembly: GCA_037114965.1
Location: CM073428.1:69128463-69150127[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.05 3.6 9.7 1.3 2 23 30 52 29 52 0.92

2 9 0.001 0.073 15.0 0.5 3 23 85 105 83 105 0.95

3 9 2e-05 0.0014 20.4 0.6 2 23 112 133 111 133 0.97

4 9 3.7e-06 0.00027 22.7 5.9 1 23 142 164 142 164 0.99

5 9 0.00016 0.011 17.6 1.0 1 21 170 190 170 191 0.95

6 9 0.034 2.5 10.2 2.3 2 20 444 462 443 464 0.92

7 9 9.3e-06 0.00067 21.4 2.1 1 23 810 832 810 832 0.95

8 9 0.00037 0.027 16.4 9.4 1 23 838 860 838 860 0.98

9 9 0.0058 0.42 12.6 4.3 1 21 866 886 866 887 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.05	3.6	9.7	1.3	2	23	30	52	29	52	0.92
2	9	0.001	0.073	15.0	0.5	3	23	85	105	83	105	0.95
3	9	2e-05	0.0014	20.4	0.6	2	23	112	133	111	133	0.97
4	9	3.7e-06	0.00027	22.7	5.9	1	23	142	164	142	164	0.99
5	9	0.00016	0.011	17.6	1.0	1	21	170	190	170	191	0.95
6	9	0.034	2.5	10.2	2.3	2	20	444	462	443	464	0.92
7	9	9.3e-06	0.00067	21.4	2.1	1	23	810	832	810	832	0.95
8	9	0.00037	0.027	16.4	9.4	1	23	838	860	838	860	0.98
9	9	0.0058	0.42	12.6	4.3	1	21	866	886	866	887	0.96

Sequence Information

Coding Sequence: ATGGCTTGCCAAAACTTAACCGCACCCTCCCTCACGAACGGCACGATAAAGGAAGAGGAGTACAGCGCGGCCCCcgaatatttcataaaatgtcCGCAATGTCAGAAAGGATGTCAAACCTTCCAGGCCCTGAAGGAGCACATGGACGCCTTTCACGCCGAGCTGTCGGCCAGTTCCGAGAATGGTAACCTCTCCATACCCAACGCGGCTTCGCCCACGCCCACACTGGCCGGTACAGGTGGGCCATTTGGCTGTTCCCAGTGCACGGCGTCCTTTTCGTCCAAGGATCAACTCGAGAAGCACGAGCTTCTGCATTCGCCCAACGCACAAGTGTCCTGCAAGATTTGCAACAAAACCTTCGCCAACGTCTACAGGCTCCAGAGGCACATGATCAGCCACGATGAGAGCGCAGTTCTTAGGAAGTTCAAGTGCACAGAATGCGACAAAGCCTTCAAATTTAAGCATCACTTAAAGgAGCACATTAGAATCCACAGCGGGGAAAAACCGTTCGAATGCGGAAATTGCGGAAAGCGCTTTTCTCACTCAGGATCCTATTCTAGTCACATGACATCAAAGAAATGTTTAGTAATGAATCTCAAGTTAGGTAGAACTAGGGCCCCTTCGAATAACTCGCTGTTGGATAAGAACGTCCAGCAGAACCTGCGGGGTCCGAAGAGGTCCTCCATGAGTCCGATAAACAACAACATCACAACTAGTCCTAATCACAATAAGTATTTGCCGATTTTACCGAAATATTCAGAAGCGGCGGCGGCAGCTTTGTTTCAGTCGTCGCTGGCGGGAAATCCCGCCATGTCCCCGTTTTATTTAGGACCCCCTAGTCTTCTAAATGCTGGCCACCCCATTAGTCCGTACACGGTGCCAACGCTGGGTCATTTACTAGAGCAGTTACAGCAACAGAGTGCTCAAAGGACAAGTCCGCTAGGACCACAAATGCTGGATAGTATAGAGTGTACCTCTGAAGAGTCGAAACCACATGAAACCTTCCACAATGTAAATAATTTCGAAAGCACTAGTGTTAAGTCGGAAAATAATGAAAACGTACACAATTCGAACTCTTCCGAATGCGGCGACTTAGTAATGGATGAAGACGCAGATCCAGAGACTGAAAACCAAAGTAAATTTGAGAACAGTGCCATCGAACATAGTACAGCTAATACCGGAGACTTGGAAGCAGTAAAAAGAATCCTAGAAACCGTGAATGCGACAGTTACCAAAGAATTATTGCAGGCCAATATGCGGAAAGTATCTTCAGATTCTTCTAATGATTCTCACAGTGTGACACCAGCACATTCCCCAAAGCAGACATTACATTGCAGTACTTGCAAAAAAACCTTTGAAAACTCCACTTTACTGGAAGATCATGAGTGTGAAGACTTACGAAGTGAAGGCCTAGCGGCAAAACTAGAAGACGCTCTTACCACGAAATCTGACGATGCTCAGAATGACAGCATAAGTGGAGCAGAAGATCAGGACTATGACAAACATTATAACACAAATGATGACGTAGATTCAGAATCGTTCACCACCACGGACCATGTTTCAGAGGATGGTAGGAAAGTTAGAGTACGATCTCTCATATCTGATGAACAGCTGAAAGTGTTGAAagacaattataaattaaatcctAGGCCAAAACGAGAAGATCTGGAGAAGATAGCAGCCAGCATTGGATTTCCAGTTAGGGTGGTTCAAGTATGGTTTCAGAATACGAGAGCTCGAGATAGACGAGAAGGTCGATTGATACAAGTTCCCTATAGCCCCGCTTCTTTACCCCGTTACCAATCCAGTATCATGCCTTTAAACTCTGGTAACCATAAAGTCTCGTTAAGTATGTCCCCAAATCAGTATATTTCAGAGCAACCACTCGACCTTTCAATTAAGAAAGAACTCAAATCAAATGAATCGACACCCGCTAGTTCTCCGAGAAGACCGTCTTCGGCTAATATTCACTCGGAAGGTATCGATGAAGTCGTCAATCTCAGCAGAAAAACATCCAGGAGTCCCACTCCTTACATGCCCTACCAAAATCATTACCACAGTTCGAATTCCTCTGAGCCCCGTCAGTCACCTTCACCTCTGGACTTCAACAGCAGTCGTTTGGCTCAAATTTTAGCACAACCAGCCCACAAACTCGCCTTACCGGGCATGGGTCTGGTACCCATGGACCAACTAATGCAGTTTGGAGCTACAGATCTTCCTAGTCTCTCTCAACTTATTAGCAGTAGGATATCTAGCCTGAGTCCCAATTCAGACAGAAGGGCGTGGAGTGAAGGGAGGGAAATACAAAACAATATGTCTGAAGACGATATGTCAAATGCCAGTAAGAGGAGTAAAATGTCACAATTCGTACTGAAGGGCCTCGGCAGTCCTGTGTTGGGAAGTCAAGAAACTGAAATTGAAGGCCAATTTACCTGTGATCAATGTGATAAATCCTTCTCGAAACAAAGTTCACTTGCCAGGCATAAATATGAACATTCagGTCAACGTCCTCATAAATGTGATGAATGCCCCAAAGCTTTCAAACACAAACATCACCTTACTGAACACAAAAGACTTCATAGTGGAGAAAAACCATTTCAGTGCagtaaatgtctaaaacgattTTCTCATTCTGGTTCCTACAGCCAACATATGAACCACCGATATTCATACTGTAAACCTTACAGAgagtaa
Protein Sequence: MACQNLTAPSLTNGTIKEEEYSAAPEYFIKCPQCQKGCQTFQALKEHMDAFHAELSASSENGNLSIPNAASPTPTLAGTGGPFGCSQCTASFSSKDQLEKHELLHSPNAQVSCKICNKTFANVYRLQRHMISHDESAVLRKFKCTECDKAFKFKHHLKEHIRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRAPSNNSLLDKNVQQNLRGPKRSSMSPINNNITTSPNHNKYLPILPKYSEAAAAALFQSSLAGNPAMSPFYLGPPSLLNAGHPISPYTVPTLGHLLEQLQQQSAQRTSPLGPQMLDSIECTSEESKPHETFHNVNNFESTSVKSENNENVHNSNSSECGDLVMDEDADPETENQSKFENSAIEHSTANTGDLEAVKRILETVNATVTKELLQANMRKVSSDSSNDSHSVTPAHSPKQTLHCSTCKKTFENSTLLEDHECEDLRSEGLAAKLEDALTTKSDDAQNDSISGAEDQDYDKHYNTNDDVDSESFTTTDHVSEDGRKVRVRSLISDEQLKVLKDNYKLNPRPKREDLEKIAASIGFPVRVVQVWFQNTRARDRREGRLIQVPYSPASLPRYQSSIMPLNSGNHKVSLSMSPNQYISEQPLDLSIKKELKSNESTPASSPRRPSSANIHSEGIDEVVNLSRKTSRSPTPYMPYQNHYHSSNSSEPRQSPSPLDFNSSRLAQILAQPAHKLALPGMGLVPMDQLMQFGATDLPSLSQLISSRISSLSPNSDRRAWSEGREIQNNMSEDDMSNASKRSKMSQFVLKGLGSPVLGSQETEIEGQFTCDQCDKSFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00885777;
90% Identity: iTF_01014137;
80% Identity: iTF_01014137;