Basic Information

Gene Symbol
-
Assembly
GCA_037114965.1
Location
CM073434.1:39270621-39282257[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.43 31 6.7 5.5 1 23 322 344 322 344 0.98
2 14 0.15 11 8.2 1.5 1 23 353 375 353 375 0.98
3 14 0.023 1.6 10.8 2.1 1 23 384 406 384 406 0.98
4 14 0.0012 0.09 14.7 0.4 3 23 417 437 415 437 0.97
5 14 0.2 15 7.8 2.4 1 23 446 468 446 468 0.98
6 14 0.0004 0.029 16.3 3.6 1 23 477 499 477 499 0.99
7 14 0.022 1.6 10.8 6.0 1 23 508 530 508 530 0.99
8 14 0.013 0.93 11.5 0.9 1 23 539 561 539 561 0.98
9 14 0.0015 0.11 14.5 3.6 1 23 568 590 568 590 0.99
10 14 0.00013 0.0097 17.8 5.2 1 23 599 621 599 621 0.98
11 14 0.02 1.5 10.9 3.0 1 23 630 652 630 652 0.99
12 14 5e-05 0.0036 19.1 0.9 1 23 661 683 661 683 0.99
13 14 0.00045 0.032 16.1 4.3 1 23 692 714 692 714 0.99
14 14 0.0022 0.16 14.0 1.7 1 23 723 745 723 745 0.99

Sequence Information

Coding Sequence
ATGCAGCCAGAAAActgtaataacatatttttttgcaaactatGTGTGAATATCATAAGCTGTACAAATTCCAAAGTTATAGAAAAAGCTGTGTGGGAGGCTTTGGAAGTTATTTGGCCCACTctgaaCTTGGAAGAGACACATAAACAATTGGTGTGTGAAACATGTTCCTCGAAATTATTTGCTGcgtataattttaagaaagcaTGTATGAATACCGAGGCCAGTATATTTCCTCATATTAACGCAGGTAAAATGTCGGTGGTCGAATTAGAAGAACTTTATCTGAAGGTGAATGGAATTATTGAGTTGACCGATATGCAAgaaaatcagaaaatttgtcGATTATGTCTTCAACGGGTAGCATACGGAGTTGTGTCACTCAACGAAGTGGATAGtgacataataaatacatttataccTGAAGTAaACATCAATGTTACCAAGGATCCCATTGTATGCGAACCATGTTTCAATTCGCTTAATATCCATGGGGGTTTTGTTATGAGCTGCCTTAAAGCAcaggaaaaatatataagtgCCGATAACCAGCCTTATATTAAGAGTGAAGTGACTGATATAAAACTGGAAGATGACCATGAGATGCAGGAGGAATATAAAAGTCTTGATGAGCAATTTTACATTAAACCTGAGGAGATCGAAATAAAGGCGGAGGAAGGATATCAAGATAGTGGTTCTATTTCACACAacataaaaaaggaaataattgAAAACGAACAGAAGCATATTTCTGAAGATATaggagaaataaaaaatgaatatatggTTGAAAGTGATAACAAGATTCAAATAAACAAATGGGATACTCCGTTAGATACACCATATGAAAATAGATATAAACAAATGTTTGAAGGCGAATTGGAACACGAAATTGATCAAAACCAAAAGTACCCTTTGGAAATCGAGATGTATAATTGTGACACACGTACTGAAAGCATAATGTACAGGTGTGATGTGTGTCATTATGAAACCAAACGTAAAAGTGACATCAAGTGTCACCTATTAACTCACAAAGACTCTTCTGAAAtcaaaatgtacaaatgtgattttTGCATTTATGAAACTAAGTATAAGAAGTCTTTGAATATACATCAACTAATACATAAAGACCCTTCTGAAACCCTAATGTACAAATGCGATACTTGTAGTTTTGAAACTAAACGCAAAAATGCCCTAAAATTACATAACttaacacacaaagacccttctgaaatccaaatgtatgGGTGTGATGTATGTGATTATGAAACTAAACGTAAGAGTGACTTGAAATATCATGAAttaacacacaaagacccttctgaaatccaaatgtacaggtGTGATGCGTGTGGTTATGAAACTAAACGCAAAGATGTGCTGAAATGTCATCAGttaacacacaaagacccttctgaaatcaaaatgtacaagtgtgatatGTGCCATTATGAAACTAACTATAAGGGTAACCTAAAAAGTCATCAATTgacacacaaagacccttctgaaattcaaatgtacaaatgtgatagtTGTACTTATCAAACTAAATATAAGAAACACCTGAAAGACCATcaattaacacacaaagacccttctgaaattcaaatgtacaagtgtgatgcATGTGATTATGAAACTAAACGCAAAGGTGTCCTGAAATATCATCAGTTATCACATCTATACCCTTCTGAATTGTACAGGTGTGATGCGTGCCATTATAAAACTAACCGTAAGGGTAACTTGAAAATGCATcaattaacacacaaagacccttctgaaatccaaatgtataaatgtgatgTATGTCATTATGAAACTAAACACAAAAGTGAGCTGAAACGTCATCAATTAATACACAGAGATCCTTCTGAAAttcaaatgtacaagtgtgatgcTTGTACTTACACCACTAAGCTTAGAAAATACCTGAAAAATCATCAGTTAACACACAAGCATCCTTCTGAAGTTCAAATTTACAAGTGCGATGTGTGCGATTATAAAGCTAACCGTAAGGGTAATCTGAAAATGCATCAATTAACACACAAggacccttctgaaatccaaatgtacaaatgtgatgcGTGTCATTATGAAACTAAACGCAAGAGTGAGCTGAAGCGCCATCGATTAACACACAGAGATCTTTCTGAaattcaaatgtacaaatgtgatgctTGTCCTTACAAAACTGATCATAGAGAAGACCTGAGAAATCATCAGTTgacacacaaagacccttcgGTATAG
Protein Sequence
MQPENCNNIFFCKLCVNIISCTNSKVIEKAVWEALEVIWPTLNLEETHKQLVCETCSSKLFAAYNFKKACMNTEASIFPHINAGKMSVVELEELYLKVNGIIELTDMQENQKICRLCLQRVAYGVVSLNEVDSDIINTFIPEVNINVTKDPIVCEPCFNSLNIHGGFVMSCLKAQEKYISADNQPYIKSEVTDIKLEDDHEMQEEYKSLDEQFYIKPEEIEIKAEEGYQDSGSISHNIKKEIIENEQKHISEDIGEIKNEYMVESDNKIQINKWDTPLDTPYENRYKQMFEGELEHEIDQNQKYPLEIEMYNCDTRTESIMYRCDVCHYETKRKSDIKCHLLTHKDSSEIKMYKCDFCIYETKYKKSLNIHQLIHKDPSETLMYKCDTCSFETKRKNALKLHNLTHKDPSEIQMYGCDVCDYETKRKSDLKYHELTHKDPSEIQMYRCDACGYETKRKDVLKCHQLTHKDPSEIKMYKCDMCHYETNYKGNLKSHQLTHKDPSEIQMYKCDSCTYQTKYKKHLKDHQLTHKDPSEIQMYKCDACDYETKRKGVLKYHQLSHLYPSELYRCDACHYKTNRKGNLKMHQLTHKDPSEIQMYKCDVCHYETKHKSELKRHQLIHRDPSEIQMYKCDACTYTTKLRKYLKNHQLTHKHPSEVQIYKCDVCDYKANRKGNLKMHQLTHKDPSEIQMYKCDACHYETKRKSELKRHRLTHRDLSEIQMYKCDACPYKTDHREDLRNHQLTHKDPSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-