Basic Information

Gene Symbol
-
Assembly
GCA_037114965.1
Location
CM073433.1:2652713-2654872[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 1.3 95 5.2 0.9 6 21 12 27 6 28 0.86
2 14 7.7 5.6e+02 2.8 0.2 1 12 131 142 131 151 0.87
3 14 0.34 25 7.1 5.5 1 19 282 300 282 302 0.95
4 14 0.019 1.4 11.0 2.1 1 23 311 333 311 333 0.99
5 14 0.00018 0.013 17.4 1.6 1 23 352 374 352 374 0.99
6 14 0.063 4.6 9.4 0.6 1 23 405 426 405 426 0.93
7 14 5.8e-05 0.0042 18.9 1.1 1 23 432 454 432 454 0.96
8 14 0.00098 0.071 15.0 0.7 1 20 460 479 460 481 0.94
9 14 0.00022 0.016 17.1 2.4 1 23 488 510 488 510 0.98
10 14 1.2e-05 0.00086 21.1 3.3 1 23 516 538 516 538 0.98
11 14 0.00019 0.014 17.3 6.4 1 23 544 566 544 566 0.99
12 14 3.8e-06 0.00027 22.7 0.3 1 23 572 594 572 594 0.98
13 14 9.6e-05 0.007 18.2 0.1 1 23 598 620 598 620 0.97
14 14 0.00045 0.032 16.1 0.1 1 23 628 651 628 651 0.96

Sequence Information

Coding Sequence
ATGGGAACCTTATCATTAAACTGTCCATTTTGCTGCGAAGAAAAGTTTACATCTTACAATTCCCTAAAATATCACATTTTGAGCATGGTTGATAATATAATGTGCCCAGCGTGTAACTGCAGGTGCGACGATATTTTTGATTTAGCAGACCACTTGGGTAGAGAATGTAAAGAAAAGGAAGTTGAACCAATTTCACAAGTCAACATAAAACGAGAGGCACATCTTGAATTGCCATCACCTAACGAAACTGACtcaaatgaattaattaatccCAAAGTTGAGATGGAGGATAATGGTTACGATAAAAGCATTTTAGAAAAAGCTTTAACGAGCTCTGACGAGCATGAAAACCTCCAGAATGATAATGAATCTGAAGAGTCGAAAGTCGTGTATATGTGCCAAATGtgcaacataaattttatctcgATTGAAGAACATTTACAAAAGTTCCATGAAGGAGAGGAAGTCATTTATgaAAGTGAAGACACAGCACATATACTAAACGAGGATCATAATCCTACAGTTCCAGAAAACGATGATGGCACAGATATCGAAGACAATATGTTCGAATTAAATGACGAAGAAGAATATGACAATAACGAAGAATATGTAGAAGGCAAGTCTTCCAAAACGATAGAAGAACAGCAGTGTTTAGATAAAGACGGTCGAGTGTACACCAGAAAGGTGGTTAAAATCGACAAATTTTGGATAGATAAAAACGATAAGCATGAGGATGATGATGGCCCAATGACAGAAAAATACCTGCTGGAGAACGGAAAAATTCGAAAGATCACCGAAGATGAAGCCGAAGTCATAGACGATAAAGAAACTATAATACAAATACATCAGTGCCCCAAGTGTTACCTGCAGTTTCCAAACCTGGACCATTACAGGAAACATTCATGCGACCCGacgaaagtaaaaaataaattcaaatgtaCGCATTGCACGGCGGTGTTTTTGAATTACCAAGCGTTAACAGGCCATATGAAATCGCATATAACAAAAGACGAAACCACAGGCAAAATTAAAAGGGTTGTCACTTTAGGCCCTTACACTTGCGATGTTTGCAATACGATGTTCCCGTCTTTCAAAAGCTTACGCCTTCACAAGAGGATGCACGACCCTATCAAAGACAAGGTCCCCGAAGCACCCGTGAGTTACAGCATTACGGGGCCCATAGACGAAAGCCGAGAAGTAGTACGTCACATGTTCATCTGCAGCATTTGCAACAAGACTTATGACAAAGAATACGAAGAGGTGCACATGAAATCGCACAGCCAGGAAGAGAATTTCAATTGTTCGGTGTGTAACAGGAAGTTTTACACGAAAGAAAACCTGGAGATGCATGTCAAAGCGCACAGCAACGGTAAAAAGTTCTCGTGCTCGTACTGCAAGAAACCCTTCACCACGTTCAACGCTTTACAAGAGCACGTTACTAATCAGTGTCAGAAACGCCAGTACGAGTGTCAGTTCTGCGGCAGGAGGTTCTCCAGACCGCACGAGAAAGTGAAGCACGAGCGAATCCATACGGGCGAGAAGCCACACGTGTGTCAAATCTGCGGAAAAGCCTTCCGCGTCAGCTACTGCCTAACGCTCCATCTACGCACCCATTCCGGTACTAGACCATACCAGTGCAACACCTGCGGCAAACGATTCAAGTCGCACAGCGTCTACAATCACCATTTGCTCACACATTCCGACGTTAGGGCGTACCAGTGCCCTTATTGCCCGAAAGCCTTCAAGACCAGCGTCCAACTAGCCGGGCATAAGAACAGTCACATCAAACCATTTGCTTGCACGGAATGCAACAGGCCGTTCGCTTCCTTATACGCCGTCAGGGCGCACATGGAGACCCACAAGAGGGACAATAACTTGAAGTTCGACTGTTGGTTGTGCGGTGCCACTTACGCACGCGCTTTCGCCCTGAGGGACCACATGAAGAGCCAGCACGCGGGTGCGAACGTTAGTGTGGACGAGAACGTTTTGATCGAGCTGGAGACTAATGAGAGCACTAATCAGATCGAGAACGAGATGAGGACTGAGATCGAGGAGCAGATGGAGGCCGAGGAAACGgcgtag
Protein Sequence
MGTLSLNCPFCCEEKFTSYNSLKYHILSMVDNIMCPACNCRCDDIFDLADHLGRECKEKEVEPISQVNIKREAHLELPSPNETDSNELINPKVEMEDNGYDKSILEKALTSSDEHENLQNDNESEESKVVYMCQMCNINFISIEEHLQKFHEGEEVIYESEDTAHILNEDHNPTVPENDDGTDIEDNMFELNDEEEYDNNEEYVEGKSSKTIEEQQCLDKDGRVYTRKVVKIDKFWIDKNDKHEDDDGPMTEKYLLENGKIRKITEDEAEVIDDKETIIQIHQCPKCYLQFPNLDHYRKHSCDPTKVKNKFKCTHCTAVFLNYQALTGHMKSHITKDETTGKIKRVVTLGPYTCDVCNTMFPSFKSLRLHKRMHDPIKDKVPEAPVSYSITGPIDESREVVRHMFICSICNKTYDKEYEEVHMKSHSQEENFNCSVCNRKFYTKENLEMHVKAHSNGKKFSCSYCKKPFTTFNALQEHVTNQCQKRQYECQFCGRRFSRPHEKVKHERIHTGEKPHVCQICGKAFRVSYCLTLHLRTHSGTRPYQCNTCGKRFKSHSVYNHHLLTHSDVRAYQCPYCPKAFKTSVQLAGHKNSHIKPFACTECNRPFASLYAVRAHMETHKRDNNLKFDCWLCGATYARAFALRDHMKSQHAGANVSVDENVLIELETNESTNQIENEMRTEIEEQMEAEETA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00110804; iTF_01227605;
90% Identity
iTF_00110804;
80% Identity
-