Basic Information

Gene Symbol
-
Assembly
GCA_963576475.1
Location
OY754983.1:1864754-1866457[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00021 0.027 16.6 0.6 2 23 123 144 122 144 0.96
2 10 0.0024 0.31 13.2 0.1 1 23 150 173 150 173 0.90
3 10 0.01 1.3 11.3 2.3 1 23 176 199 176 199 0.96
4 10 1.1 1.4e+02 4.9 9.3 1 23 205 228 205 228 0.96
5 10 0.0044 0.57 12.4 4.2 1 23 349 371 349 371 0.98
6 10 0.098 13 8.2 4.4 1 23 374 397 374 397 0.94
7 10 1.4e-06 0.00018 23.5 1.5 1 23 402 424 402 424 0.98
8 10 7.4e-05 0.0095 18.0 1.0 1 23 430 452 430 452 0.97
9 10 1.2e-05 0.0016 20.5 0.6 1 23 458 480 458 480 0.97
10 10 1.3e-07 1.7e-05 26.6 1.4 1 23 486 508 486 508 0.99

Sequence Information

Coding Sequence
atgttccaCGAGGTCGATTTCGATGTTTTGGATATCACTCAAAAGGATATTAAGAAAGAAGCCGAATCAATAAGCGATTGTGACGAATTGCTTCCAATTGCTCAAATCAATTTTGTCCCAAACAACTTTTCCGAAACAGACTTAGACAATCACAAGTATAAATTTAATTGCGCTGTTGTAAGCCTTCCAAATTTAGAACTTAAAGATGCACGTAATGGCGACCCTTCACGAAGTAATGCTTATAAGTCACAGTATATGGGAGATAACTTTGATACAGTACTTAAGAAAGAAACTGATCCCATAATTGATAAAAACTCACCAACTCGAGACAATAAGGGACGATTTATTCGTACTAAAGGCGAAATTCCTTGCAACAAATGTGATAGGACTTTCGATAGAGTTGTCAGTTTTAGGGAGCACCGGAAGGTTCATCTTCACAAGACGACTTTTGAATGTGAGGAGTGCGGTAAAGTTTTTGTGGAAAAGATCAAATTGGTATTTCACCTCCAAGTAGATCACATCAAATATCCATGTAGAATGTGCAGTTTGAAATTCGACAATCGTAAATGTTTGATGTCTCACTTGATGCAGGCACATTACAAAAAGACAACGCACAATTGCACTAAATGCTGCAAAACATTTCATACGAAAGACCGTTTACAATATCATATTAAATCTGTTCATTCAAAAGTAAAGAGAGCAAAGTTTTGGCAGCAGGGTGAGAAAGATCTTAATTCATCTCCTGTTCCAAAGCATGATGAATCTCATTCCCACAGTATCGAAAACAAAAGTTTCACCCAAGAAATGGTCAAAAACGAAATTGTATCAAATTTACAAGAAGCATCGCCTAAACTACCAACACTTGTTAGTTATAATGAAGGTATTAAAGATGAATATAAGGCCAGTGTTGTTTCTGTAGATACTTTGTTAATAAGTAAAGATGAATATAAGGCCAGTGTTGTTTCTGTAGATACTTTGATAATAAGTAAAGCAACAGTCAACTACCGTGACGAAAAAGGTAGATTTGTACCTAGCCAAAGTCGATATATGTGCGACAAATGCGAACAATCTTTTTCGACAATGAATGAACATAAGAAACATTTGAGAACTCACTTAGTGCACAAATGTAGTTTTTGTCATGAAACGTTCACAGGAATCTCGGTCTTGAAGTTGCATAAGAAAGAAAATCACGCTGATCTTAAATTTACATGCGACGACTGTGATAaagtttttaaattgaaaaGTACTCTTAAAGCTCATAAATTGCGACACACTGGCTCTAAACCATATAAGTGTAACGTTTGTGAAAAGGAATTTTCACATATAAATTACCTGAAAGCCCATGAAATCATTCACGATAAGAAGAAACCGTTTCAGTGTGATAAATGTGGTAAAGCTTTTACACAGATTGGTACATTGAAATATCATAAAATCATTCATTCAGGAGCAAAACCTTTTCAATGTGACGTGTGTGGTAGAAGTTTTGCGCATCCAAATTACTTGAAAACGCACATGAAAGTTCATCGATAG
Protein Sequence
MFHEVDFDVLDITQKDIKKEAESISDCDELLPIAQINFVPNNFSETDLDNHKYKFNCAVVSLPNLELKDARNGDPSRSNAYKSQYMGDNFDTVLKKETDPIIDKNSPTRDNKGRFIRTKGEIPCNKCDRTFDRVVSFREHRKVHLHKTTFECEECGKVFVEKIKLVFHLQVDHIKYPCRMCSLKFDNRKCLMSHLMQAHYKKTTHNCTKCCKTFHTKDRLQYHIKSVHSKVKRAKFWQQGEKDLNSSPVPKHDESHSHSIENKSFTQEMVKNEIVSNLQEASPKLPTLVSYNEGIKDEYKASVVSVDTLLISKDEYKASVVSVDTLIISKATVNYRDEKGRFVPSQSRYMCDKCEQSFSTMNEHKKHLRTHLVHKCSFCHETFTGISVLKLHKKENHADLKFTCDDCDKVFKLKSTLKAHKLRHTGSKPYKCNVCEKEFSHINYLKAHEIIHDKKKPFQCDKCGKAFTQIGTLKYHKIIHSGAKPFQCDVCGRSFAHPNYLKTHMKVHR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-