Mcic000421.1
Basic Information
- Insect
- Mochlonyx cinctipes
- Gene Symbol
- ZNF438
- Assembly
- GCA_001014845.1
- Location
- JXPH01029496.1:1656-3170[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.027 1.1 10.0 2.8 2 23 31 54 30 54 0.91 2 13 2.8 1.2e+02 3.7 3.7 1 23 99 121 99 121 0.97 3 13 3.6 1.5e+02 3.3 0.9 1 21 157 177 157 180 0.77 4 13 6.8e-05 0.0028 18.2 4.6 1 23 193 215 193 215 0.96 5 13 0.00016 0.0067 17.0 3.7 1 23 221 243 221 243 0.98 6 13 2.3e-05 0.00094 19.7 0.5 1 23 249 272 249 272 0.96 7 13 0.00017 0.007 17.0 1.3 2 23 281 303 280 303 0.95 8 13 0.0017 0.073 13.7 0.8 2 23 334 356 333 356 0.94 9 13 0.0033 0.14 12.9 1.3 3 23 366 386 364 387 0.94 10 13 5e-06 0.00021 21.8 0.9 1 23 391 413 391 413 0.98 11 13 5.7e-06 0.00024 21.6 1.6 1 23 419 441 419 441 0.97 12 13 0.00033 0.014 16.0 0.6 1 23 447 470 447 470 0.96 13 13 0.0022 0.093 13.4 0.3 1 23 476 500 476 500 0.97
Sequence Information
- Coding Sequence
- ATGAGTCCAAAGATGCTGCAGCAAGAACACAAAGACGATGACAATATGGAAAAAGAGTCAGTTGCTAAATCGATTAAAAATGATATTAAGAAATGTTTTCTGTGCACGAAACCAAAACCTTTTAGTAGAAATGATCACCTGAAAATACATCTTAGTCAACATGTATGTCAACTGCCCCTCAGTTGTGAGAGTTGTGCATTCCAAACTGATAATGTAGAATTGGCAAACAACCACCTCGCTGAGCACAACCCAACAAAGACCTATGATTACACTTTggaacttaaaaattttaattttaaatgctaTCTCTGCAATTCAGTACACGAATCAGAAAATCATCTGAAAGATCATCTAGAAACTCACCTGGATTTTCTTCCTTTCAGTTGTAAATTCTGTGAAAACGTAAAAGTATCGACTGTGAATGGTGCCAACAAGCACATGAAGTTACACGATGAGATCGAAAGGCCCTACAAATGTGCTTTTTGTGAAGTACGGTTTAAGTACGCTCGTGTGAAATCAGATCACGAAAAGAACATTCACTTGAAAAGAGAATTGGCCGTAATGCCAACGAAAATCCATCAATGTACATTTTGtggaaaaactttcaaaaaacatTCATCATTGACCGATCACGAAGCTATTCacaatcaaattaaaaagtATTCTTGCAATAAATGCGATAAGAAATTCGCATCCCGAGGAAATTGCGCACGCCATCAACGTCTCCATTTCGAATTCAGGCCATTCAAGTGCACCAAATGCCCGGCCCAATTCAATCAAAAAGGAAACTTGGAAAGTCACCAAGCTGTGAAGCATGTCGGTTCATctaacaaaaaaatgaaatgtagTTATTGCGAGAAATCTTACTCTTCAGACATTTCTTTGACTCGTCATATCAAATTTTATCACTCAACTACTAGAAAAATTACCGCTACTTCCACCAAAACCCCCTCGAAAGCCACTGTgcagaaaaaaaagattatacCGCCTGATTtgaataaatgcaaattttgtggCGTTTCCTTCAAGTACCATCCTGAATTGATCGAACATCTTGAAAATGAACATTCTGAAgaggaaattgaatttttattttgtgaacaATGTGGTGCTAAATTCATGAACAATTATCGGTTGGCGTTACATATGCAATACCATCATAATAGGGAATACAAGTGTCAGATTTGCGATAAAACCTTCAAATCCAAAACGGGGTTGGATGAACATCTTACAGTCCACTCTGGAATACAACGCTTTGCCTGCGATTTGTGCGACACCAAATTCAAAACATCAAAGAATCTCATCCGGCATAAGAAAATCCATTCAGATACTCGAGATTTCCCATGCGATATTTGTGGCCGTGCCTTTCGCGCACGCCTTCATATGCAAACCCATAGACGCGGCGTCCACACTAAAGAAAAACCTTTTCCATGCCCGTATCCGAATTGTGAACAAATGTTTGGAGACCGCGGATTGCTGAGCAAGCAtaaaaagaaacatttaaatgaaaattaa
- Protein Sequence
- MSPKMLQQEHKDDDNMEKESVAKSIKNDIKKCFLCTKPKPFSRNDHLKIHLSQHVCQLPLSCESCAFQTDNVELANNHLAEHNPTKTYDYTLELKNFNFKCYLCNSVHESENHLKDHLETHLDFLPFSCKFCENVKVSTVNGANKHMKLHDEIERPYKCAFCEVRFKYARVKSDHEKNIHLKRELAVMPTKIHQCTFCGKTFKKHSSLTDHEAIHNQIKKYSCNKCDKKFASRGNCARHQRLHFEFRPFKCTKCPAQFNQKGNLESHQAVKHVGSSNKKMKCSYCEKSYSSDISLTRHIKFYHSTTRKITATSTKTPSKATVQKKKIIPPDLNKCKFCGVSFKYHPELIEHLENEHSEEEIEFLFCEQCGAKFMNNYRLALHMQYHHNREYKCQICDKTFKSKTGLDEHLTVHSGIQRFACDLCDTKFKTSKNLIRHKKIHSDTRDFPCDICGRAFRARLHMQTHRRGVHTKEKPFPCPYPNCEQMFGDRGLLSKHKKKHLNEN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -