Mcic004416.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mochlonyx cinctipes
Gene Symbol
ZFX
Assembly
GCA_001014845.1
Location
JXPH01053911.1:971-3940[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 8.7e-06 0.00036 21.0 2.9 1 23 163 185 163 185 0.99
2 16 0.0061 0.25 12.0 5.9 1 23 191 213 191 213 0.98
3 16 0.0036 0.15 12.8 1.9 1 23 221 243 221 243 0.97
4 16 2.7e-06 0.00011 22.6 0.9 1 23 249 271 249 271 0.97
5 16 5.7e-06 0.00024 21.6 0.9 1 23 277 299 277 299 0.98
6 16 7.5e-07 3.1e-05 24.4 1.6 1 23 305 327 305 327 0.99
7 16 0.00022 0.0089 16.6 2.2 1 21 333 353 333 354 0.94
8 16 7.3e-07 3e-05 24.4 0.1 1 23 360 382 360 382 0.98
9 16 8.9e-07 3.7e-05 24.1 0.9 1 23 391 413 391 413 0.98
10 16 2.2e-05 0.00092 19.7 2.2 1 23 419 441 419 441 0.98
11 16 0.01 0.43 11.3 2.4 1 19 447 465 447 468 0.87
12 16 0.0024 0.1 13.3 0.7 2 23 479 500 478 500 0.97
13 16 9.6e-06 0.0004 20.9 2.5 1 23 582 604 582 604 0.97
14 16 5.1e-05 0.0021 18.6 0.2 1 23 611 633 611 633 0.98
15 16 0.00022 0.0091 16.6 3.3 1 23 641 663 641 663 0.97
16 16 1.8e-07 7.6e-06 26.3 0.1 1 23 669 691 669 691 0.98

Sequence Information

Coding Sequence
ATGGCTGAAGACTTGAGGATTCGTAATATTGGGTTcgaaaatgaagaaaaaactgTTTGCCGTCTATGTTTGAAGCACGGACATCCGATGCAACCGTTGTTCCTGGGAAACGCAATACCAAATGAGTTGCTCTTGAAAAAGATCTATGATTGCACAGCAATACAGataaGTATTGGTAACGAACTGCCACTCTCCATATGTaaattgtgcaaaaataaattgaatgagTATTACGATTTTCGAGAAAGATGTCTACAGAACGATATCTTTCTCAAGAATAATCGGCTTCCAGCTAAAGCAATCAAAGCAGAAAAGCTTGAAGATAACTATCCGGATGAAAAACCTTTGAATCTTATAACTCATCATTTCACAGATTTGATAACAGAATTCAAGGCTGAAGATTACCAAGTCTTAGATTGTTCAATGAAAAAGAACCCACACGTTTCAGATGACGATTTTGCACAGGATAGTACAGGGGAAAAGAGATTCAAATGCAATTTCTGCGACTTTTCCTTTGAATACAAATCTCAATTACAAATTCATGTAAGAAAACACAATAACGAACGTCCATTCTCTTGTCGAGTTTGTTTCAAAACGTTTAAAATTCGTCATCATGTCATCATCCACATGAAAACTCATATGGAAGAGAACCAAAACAAGTTTAAATGTCATTTATGTTCTGAGGAATTTGCCAAAGTGACGGACTTGAACAATCATCGATTGCAACACAACGACAAACAATTCTTCAATTGCTCGAAATGCTCAAAAGTATTTATTAATAAAGGTAATTTAATCAATCATCTGCAAAGTCATGCGGAGGAGCGTTTTTTCAGCTGCAACATATGTGCCAAATCATTTAAATACAATGTTCAACTGAGACTACATTTGAGAATACATAATAACGaaaagccATATAAATGTGAGATTTGCACGCGAGCCTTctcacaaatttcaaatttacgaTCCCACCGTAAAACACACTCAAAAGTACGCCCGTACCACTGCGAGTATTGTACTAGAAGCTTCACGATGCAAGAACATCTCAACATTCACCTGTTAAAGTGCTCCAAGGACAAATTCAGATGCACAATATGTCCAAAGTCATTCGCCAAAGAAGGAAATCTGATTGCACACATCCAGTCACACGCGGACGGCGTTCCGGTCAAGCAATTTTCCTGTGACACTTGTCCAAAATCATTTAGGAACAAAGAGGATTGGAAGCGACATGTTCGGGTTCATACAGGCGAAAAACCATTCTCTTGCGATTTTTGCTTTAAAGGATTCGCCCAAAAAGCTAATCTGAGGTCTCATTACAAGACGCATCTACGGCCAACTTGCTACAAATGCCAGAATTGTGGAAAATCTTTCCGAAGCGAGAAAATATTGGAAACACATTGCCAAAAATGTGTTGACGATAAATATTCTCAAAGTTTATACTGTAACGAGTGTAGATTGAGTTTTGACACAGATTTTGATTTACAAATGCATTTAAAATCACATGAAATTGTTGAAAACCTTCCAAAAACAACACCGAGCCCAGTAAAAGTTGAAGTTGAAATTTCATCTTCTATAAGAAATAGTTTTCATCTCAATCATGAATTTAAAGCCGAAAATTCGGTTAAACCAAACGTTTTTCAAGTTGATAATATAACAGCAAACGGGTTTCAGTATGAAAGTTTTAAAGAAAACGGATTTCAGGGTGAAAGTATTGGAAATTATTCAGCAGAGAACGATGAAAGACCATTTAATTGTGAAATTTGTacgaaaaactttaaatttagtCGCAATTTGAAAGTACACATGAAACTGCATACAACTATAAACAACTATTTTAAGTGCGACAAGTGtccaaaaatatatgaaaatccAATGGAACTCAAAGAACATCTGTTATCGCATCCAATTGACCAGGATAGGATACATTACTGCTCATTCTGCTCAAATTCATTCAAATCAGCTGAAGATTTGAAACGACATGTTCGGTCTCATACAAATGAGCGCCCTTTTCAATGCCCAGTTTGTCCCAAAGCGTTCACGCAGCTTTCAAATTTGAGAGCGCATGGAAAAATACACCAAAAAAGAGaatttatatttcataataattttatttcttaa
Protein Sequence
MAEDLRIRNIGFENEEKTVCRLCLKHGHPMQPLFLGNAIPNELLLKKIYDCTAIQISIGNELPLSICKLCKNKLNEYYDFRERCLQNDIFLKNNRLPAKAIKAEKLEDNYPDEKPLNLITHHFTDLITEFKAEDYQVLDCSMKKNPHVSDDDFAQDSTGEKRFKCNFCDFSFEYKSQLQIHVRKHNNERPFSCRVCFKTFKIRHHVIIHMKTHMEENQNKFKCHLCSEEFAKVTDLNNHRLQHNDKQFFNCSKCSKVFINKGNLINHLQSHAEERFFSCNICAKSFKYNVQLRLHLRIHNNEKPYKCEICTRAFSQISNLRSHRKTHSKVRPYHCEYCTRSFTMQEHLNIHLLKCSKDKFRCTICPKSFAKEGNLIAHIQSHADGVPVKQFSCDTCPKSFRNKEDWKRHVRVHTGEKPFSCDFCFKGFAQKANLRSHYKTHLRPTCYKCQNCGKSFRSEKILETHCQKCVDDKYSQSLYCNECRLSFDTDFDLQMHLKSHEIVENLPKTTPSPVKVEVEISSSIRNSFHLNHEFKAENSVKPNVFQVDNITANGFQYESFKENGFQGESIGNYSAENDERPFNCEICTKNFKFSRNLKVHMKLHTTINNYFKCDKCPKIYENPMELKEHLLSHPIDQDRIHYCSFCSNSFKSAEDLKRHVRSHTNERPFQCPVCPKAFTQLSNLRAHGKIHQKREFIFHNNFIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01011898;
90% Identity
iTF_01011898;
80% Identity
iTF_01011898;