Basic Information

Insect: Mimas tiliae
Gene Symbol: ZNF296
Assembly: GCA_905332985.1
Location: HG995238.1:1466956-1485812[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.013 0.89 10.5 0.1 3 23 121 141 119 141 0.96

2 15 0.0017 0.12 13.3 2.6 1 23 305 327 305 327 0.99

3 15 1.1e-05 0.00073 20.2 0.2 1 23 333 356 333 356 0.97

4 15 0.061 4.2 8.4 2.1 1 19 361 378 361 380 0.76

5 15 2.8e-05 0.002 18.9 1.0 2 23 535 556 534 556 0.97

6 15 0.00071 0.049 14.5 4.9 1 23 562 584 562 584 0.98

7 15 0.035 2.4 9.2 4.7 1 23 643 665 643 665 0.96

8 15 0.93 64 4.7 0.1 2 23 673 694 672 694 0.96

9 15 0.0031 0.21 12.5 4.1 1 23 700 722 700 722 0.95

10 15 8.5e-06 0.00059 20.5 0.5 1 23 729 751 729 751 0.97

11 15 0.00059 0.04 14.8 2.1 1 23 760 782 760 782 0.98

12 15 0.00034 0.023 15.5 0.4 2 23 829 850 829 850 0.96

13 15 0.0074 0.51 11.3 5.7 1 23 867 889 867 889 0.97

14 15 9.6e-07 6.6e-05 23.5 0.6 1 23 895 917 895 917 0.98

15 15 1e-06 7.1e-05 23.4 3.1 1 23 923 946 923 946 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.013	0.89	10.5	0.1	3	23	121	141	119	141	0.96
2	15	0.0017	0.12	13.3	2.6	1	23	305	327	305	327	0.99
3	15	1.1e-05	0.00073	20.2	0.2	1	23	333	356	333	356	0.97
4	15	0.061	4.2	8.4	2.1	1	19	361	378	361	380	0.76
5	15	2.8e-05	0.002	18.9	1.0	2	23	535	556	534	556	0.97
6	15	0.00071	0.049	14.5	4.9	1	23	562	584	562	584	0.98
7	15	0.035	2.4	9.2	4.7	1	23	643	665	643	665	0.96
8	15	0.93	64	4.7	0.1	2	23	673	694	672	694	0.96
9	15	0.0031	0.21	12.5	4.1	1	23	700	722	700	722	0.95
10	15	8.5e-06	0.00059	20.5	0.5	1	23	729	751	729	751	0.97
11	15	0.00059	0.04	14.8	2.1	1	23	760	782	760	782	0.98
12	15	0.00034	0.023	15.5	0.4	2	23	829	850	829	850	0.96
13	15	0.0074	0.51	11.3	5.7	1	23	867	889	867	889	0.97
14	15	9.6e-07	6.6e-05	23.5	0.6	1	23	895	917	895	917	0.98
15	15	1e-06	7.1e-05	23.4	3.1	1	23	923	946	923	946	0.98

Sequence Information

Coding Sequence: ATGGACAATATGGATCCTCTGAGTAACTATGAGTATCCAAATTATGATGCCTACAGCAACCTCACCGTTCCATACTCATACGACCAGAGTGTCAAGCCAGAGTTACAGCATTACAACTACAACTTAAACATAGTACCACTAATGAACAATGGGACGGAGATTCAAAACACTGTAGCTGAACAAAATCATGAGCCATGTAACAGAACAGAGAATGAACCTGTACCAAACGAGACGGTGAAACCAGCAGAAGATGTCAAACCCGTAATCGATGGTACTAAAGTTAAAAAAGAAAAGTCGAGAGGCAAAAAGAGCAGTTACTGGTCAGTAAAGATACCAGACAAAGACTTTGCATTCTACGGCTGTGCTGTATGTAACATAAGTTTCACAACTCTGCAGGAGTTAGACCAACATGTGACTGTACATAAAGACAGAATCACCAGTTACGATCTAAGAGTGCAGAATCAGATAAAAAAGAAACAATTGAAAAAGCAAAAGAAATTAAAGTTAAAAGAAGAGAAGAAAGAGTTTGATATTGAAATAAAACCTGAAGATGGGTACATAGGTGGAGAGAAAGCTTCAGAATATATTAGTAATGAGAATAACCTAAGTGATCTAAATAATGAGAATATCCTACATAATCTCAATAATGAGGATAATGTAAATAATCTCAACAACGAGACTCACATAAATAATTCCGATAATGAAAATAACGTAAATAATCTCAATAATGAGAATAACGTAAATAATAAAAACAATGAGAACAACCTAAACAATATTAGTAATGAGAATAACAAGAAAAATGATGCGAAGAATTCGGAAAGTGATCTTAGAAAGAAATTTCTTCAGAATGTGGTGAAAGAGGAAGACAAATGCCGGGAAATCGACAAGAGCTTGCTTAACTTGCAGAAGATTTACAAGTGTTTTGCGTGTCAGAAGCAGTTCTCACTCAGTTATTATCTAAGGCTGCATGTCAGGTCCCATACTGATGAGAAACCGTACACATGTCCTGTATGTGGTCAGTCTTTCATCACGGCCAGCAAGCTGGGCCGCCACAACAAACGCATACACCTCGCCATCAGATACCAGTGCAGGATATGCTATAAATTCTTCTCGCAATTTGATTTGCTAACGCATTACAACGCAATCCTGCCCTACCTCAAAGAATTAGAAGAGCAGCTGAAAGAGAAATCTGAAGCGGAGAAGAAACCTAAACAGGAAGAGCTATGGCCGGACCAGTGGGCCCCGGAGACTGCTGATGTGGAACAAGACAAGAAACCCAAGGAACAGGACGGGACGAAGAACGAAGAAGACACGAAAGAATTCTTCCTAGAGATAGAGCCGACATCCAATATAATTGTGGAGAATGTTAAGATCCTGATGGAAGACGAGACGCTGGTCAAGAAGGAGGAAGAGGATATTGGGGATGCACAGGACAATAGCATGGATGTTAAGGATGAGAGAGACTTCTCGGACGAGGATTATTTTCCGTCGAACACATGGGCTCGCGTGTCTCCCCCTCCTCCTCCTGTAGAGAGCGAGTCTCGTGGTCGTCGCTCGGCAGGTGCGGCGGGTACGTCACGTACGTCACGTACAGGTCCGCTGTCATGTGACGTGTGCAACAAGCGCATCAGCTCGCGCACGTACCTGCGCGTGCACATGCGCACGCACACCGGCGAGCGGCCGTTCAAGTGTCACGTGTGTCAGCGCGGGTTCATCACCTCCAGCAAGATGCATCGACATGCGCTCACGCATGAAGACCAGGCTAATGGTGATGTTGATGTGAAACAGGAGAAAATCAAAGAAGAAGGTAATGAAGACAATGATGAAACTGAAGTCAAACTTGAAGGGGAAGAAAAGAAAAAATCGAAGAAGAAACGGCCCAAGAAAGAAGTTGAGAAGCAGAAGAAACGATATCAGAAGAGGCCGCACGCGTGTGAATATTGTCAGAAAAGATTCCTCCACCTGGACACGTTGCAAGTGCACAAGAAGTCCCACGAGGGTGAGACGCTCGTGCTGAAGTGCACGTACTGCTTGGAGGAGGCTCCTGACGAGGAGTCGCTCAGCTCTCATGAGAGCACACACACCGGACCGAAGCCCTATCTCTGTACACTCTGCGGCAAGACGTACAAGAAACGGGAGACGCTGGTGTATCACCGCAAGCATCACAAGCCGGGCCGCGACGAGTACATCTGCGACATGTGCTCCAAGCGTTTCTCATCCCCGGGCAAGCTGCAGCGCCACCTGGTGTCGCACCGCGTGGACAGGTTCGTGTTGCGGTACGAGTGTCCCGTCTGTGCGCACATGTTCAACACGAAGTATCACGTGCAGATGCATCTCGCTACACATCAGAAGGAGGGACTGATAATGGAAGAAAACCGCAACGAAATACTAGCGATGGTGTTACAAAACGCACGAAAAATCCCGAAACAACCAGACGCGCCCGCCAACCTCACCGACCTCATGCCGTCAGACGAGCGAAGCCGCGTGTGCAACATATGCGGTGAGGTGTTCCAACATTTCTACTACTTGGAGGAACATCTCAAAGGCCACGGCTCCAAAATAGCGATCGAGGACCTCGACAAGCCGGAAGAAAAGAAATACACATGCCAAGTGTGTCAGAAATCATTCAAGTTACATTATTATTTGAAACTCCACAGCTTTACGCATACGAAAGAGAAGCCGTTTATATGCCAACAATGCGGCAAAGGCTTTATAACTAAAGGAAAACTGAAACGGCATATCGAGACTCATACGGGACTCAAAAAGTATCAATGTCATGTATGCTATAAGTTCTTTACTAGGCCGAGTTATTTGCGCATTCATGTGAGGACTATACACGGAACTCAGGACTACAACTTCAGACTAGACAAGGATTACGGTATGGGTTCTTTTGGGGCGTTGTCGGTCATGACCCAACTGACACAGAGCAGTATGTAA
Protein Sequence: MDNMDPLSNYEYPNYDAYSNLTVPYSYDQSVKPELQHYNYNLNIVPLMNNGTEIQNTVAEQNHEPCNRTENEPVPNETVKPAEDVKPVIDGTKVKKEKSRGKKSSYWSVKIPDKDFAFYGCAVCNISFTTLQELDQHVTVHKDRITSYDLRVQNQIKKKQLKKQKKLKLKEEKKEFDIEIKPEDGYIGGEKASEYISNENNLSDLNNENILHNLNNEDNVNNLNNETHINNSDNENNVNNLNNENNVNNKNNENNLNNISNENNKKNDAKNSESDLRKKFLQNVVKEEDKCREIDKSLLNLQKIYKCFACQKQFSLSYYLRLHVRSHTDEKPYTCPVCGQSFITASKLGRHNKRIHLAIRYQCRICYKFFSQFDLLTHYNAILPYLKELEEQLKEKSEAEKKPKQEELWPDQWAPETADVEQDKKPKEQDGTKNEEDTKEFFLEIEPTSNIIVENVKILMEDETLVKKEEEDIGDAQDNSMDVKDERDFSDEDYFPSNTWARVSPPPPPVESESRGRRSAGAAGTSRTSRTGPLSCDVCNKRISSRTYLRVHMRTHTGERPFKCHVCQRGFITSSKMHRHALTHEDQANGDVDVKQEKIKEEGNEDNDETEVKLEGEEKKKSKKKRPKKEVEKQKKRYQKRPHACEYCQKRFLHLDTLQVHKKSHEGETLVLKCTYCLEEAPDEESLSSHESTHTGPKPYLCTLCGKTYKKRETLVYHRKHHKPGRDEYICDMCSKRFSSPGKLQRHLVSHRVDRFVLRYECPVCAHMFNTKYHVQMHLATHQKEGLIMEENRNEILAMVLQNARKIPKQPDAPANLTDLMPSDERSRVCNICGEVFQHFYYLEEHLKGHGSKIAIEDLDKPEEKKYTCQVCQKSFKLHYYLKLHSFTHTKEKPFICQQCGKGFITKGKLKRHIETHTGLKKYQCHVCYKFFTRPSYLRIHVRTIHGTQDYNFRLDKDYGMGSFGALSVMTQLTQSSM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00063798;
90% Identity: -
80% Identity: -