Mlon014600.1
Basic Information
- Insect
- Microvelia longipes
- Gene Symbol
- lola
- Assembly
- GCA_018340805.1
- Location
- JACMZG010001859.1:9110619-9129492[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.05 6.1 8.6 0.5 1 21 26 46 26 47 0.95 2 9 0.0072 0.88 11.2 5.3 1 21 105 125 105 126 0.95 3 9 0.017 2.1 10.1 0.3 1 21 134 154 134 155 0.93 4 9 0.00026 0.032 15.8 0.3 1 21 162 182 162 183 0.94 5 9 0.058 7.1 8.4 1.2 2 19 192 209 191 214 0.92 6 9 0.0013 0.16 13.6 1.3 2 20 229 247 228 249 0.91 7 9 0.0031 0.38 12.4 0.2 3 23 259 280 258 280 0.93 8 9 2.4e-06 0.00029 22.2 2.9 1 21 285 305 285 306 0.95 9 9 0.0018 0.22 13.1 0.6 3 23 316 337 315 337 0.94
Sequence Information
- Coding Sequence
- ATGGTTTATAGACCTTATAGCAAGAGTAGATTGTGTGCTTTCCTCTCTGTTATACACCgatACCGCATAAATTTCTACGTTTGCGGCAGTTGTGGTGATAAGTTCAAGCAAGTTCGCTCGTTTACCGCTCACCGCAAGTACGACTGCAGAGTGGCACCGGAATTCGAACCCGGCTGTTACCAAGATGTAGAAAATCGTAAGAGATGGCTTGGAATATCAGCCGATAATCTGACTATCAAACAGACGCCCCCTCACAAGTTTTTCTGTCCCAGATGGGAACTCATGGAGTCACTAATGAAGTATTCGAAAAAGCACACATGCACCAGATGCGGACGGCAGTATAACTTCTCGTGTAGTTTGAAGCGTCACATTAAATACGAGTGCGGCAAACAGTCACAATTCTCCTGCCCTCATTGTCCTTACAGCGCAAAGTACTTGAACAGTATTAAACGGCATGTGATTACTACTAAAGTCAATGgaaaatttatttgtgtatCATGTGGAAGGACTTATGCTCATAAAGGGAACTGGAGACGCCACGTTCGGTTGGAGTGTAATAAAGAGCCTTATATATCGTGTCCTTATTGCCCTTATAAGGCTAAACAGAAAGGAAGTGTTAAAAGACATTGTATACTGAGACATTCGGAAAGTGCAGTAATTACAGATGACACTGAGAAGAAACACGCATGCTTGGCTTGTGGTAGACGCTACTTTAGACCCCATCATCTTAAACGCCATATTGCTCTGGAGTGCGGCAAAGAGCCGAAGCAAGCTTGTCCTCTTTGTCCTTATAAGGCAAAACAGAAGCCAACGTTGAAGAGACATATAAGCGACATGCATActCAACATAAATTCTCTTGCACGACGTGCGGACGATGTTACTCCACTAAAGGAAATCTGAGGAGACATCTAAACTATGAATGTGGCAAGGAGCCGATGGCTATTTGTCCTTACTGTTCATACAGAGCTAAGCAAGTCGGTCATCTCAAACGCCACATTATCCTTCGACATGGAAACGGTGCTAAAATCAACCCGGAAGTTTTCGCTGTTATCAAAGAAGAGAGCAGTTTGCTGCatcaattcttttaa
- Protein Sequence
- MVYRPYSKSRLCAFLSVIHRYRINFYVCGSCGDKFKQVRSFTAHRKYDCRVAPEFEPGCYQDVENRKRWLGISADNLTIKQTPPHKFFCPRWELMESLMKYSKKHTCTRCGRQYNFSCSLKRHIKYECGKQSQFSCPHCPYSAKYLNSIKRHVITTKVNGKFICVSCGRTYAHKGNWRRHVRLECNKEPYISCPYCPYKAKQKGSVKRHCILRHSESAVITDDTEKKHACLACGRRYFRPHHLKRHIALECGKEPKQACPLCPYKAKQKPTLKRHISDMHTQHKFSCTTCGRCYSTKGNLRRHLNYECGKEPMAICPYCSYRAKQVGHLKRHIILRHGNGAKINPEVFAVIKEESSLLHQFF*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -