Mlon007114.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Microvelia longipes
Gene Symbol
BCL11A
Assembly
GCA_018340805.1
Location
JACMZG010000008.1:67347828-67367343[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 4.7 5.8e+02 2.4 0.0 2 11 54 63 53 66 0.88
2 7 6.8 8.4e+02 1.9 0.2 1 23 185 208 185 208 0.88
3 7 5.2e-07 6.3e-05 24.3 4.6 1 23 492 514 492 514 0.97
4 7 1.5e-05 0.0018 19.7 5.4 1 23 520 542 520 542 0.99
5 7 1.9e-07 2.3e-05 25.7 2.9 2 23 859 880 858 880 0.97
6 7 1.3e-05 0.0016 19.8 3.3 1 23 886 908 886 908 0.99
7 7 8.7e-05 0.011 17.3 0.4 1 22 916 937 916 937 0.97

Sequence Information

Coding Sequence
ATGAGTCACGTGGTTAGTAAGGTGGTATTAACCTCTGATTCTGACCAGGGACTAGAGGGGGCGGTAAACATTCGTATTCCTGGAGAAGTCAGAGTAGGAAGGGTGTCTATCGATCTTTGGGGAGCGGATCTCGGTGAAGGAGAAGAGGAAGACGTACTGACGTGCGGAGTCTGCCAGAAAGCCTTCGCTTTGGCTGACATCGTGCGCTTCATCCAACACAAAGTCAAATCCtgtgtaaataaagaaaactatcTTAACTGTGGCGAGCAATCAAACGGTGGTGGGTCTGGGAGCGGTGGCGAGTCCAGCGAGTTAGTCAGGAGACCTGCACCCATACTTGGAAGTGCGCCTTCAAGAAGTCCCGATAGGTGTAGTACGCCTAAGAGGCGGCCACGAACACCTCCCACCCCTCCTACCCCGGATccaaatttactaattaaacaAGAACATGTAGATTCCTCAACACCTCCTCATTCATCTCCCGATGAAGGTCCCTGCAAGAAACTCAGGACCGATGCCACCTCCAACACAACCAATTCTGAACCAAGTAACTACGTATGTTCGACGTGTAAAGCTCGGATGTACTCTGCTTGGAGATTAGTGCAACACGTCCAGAATAGTCATGGGATGAAAATATACGTAGAATCTGCTCCAAGCTCATCCTCTTCGTCTGGAAGCTCCTTAACATCATCTCCCGGAGCAAGACATAACAGTTCTTCGGGATCAACATCTTCAGCATCATCGTCAGGACCAGGGCCGTCAACATCATCCTCATCCATGGTGCCAACTAGTCTTGGACTAACTTCGCCTCTTGTAGATCCTCACCTACCCATGCATAACCCTTTTGCCGTCAGTGGGTTAGTAAGAATGCCTATTGAACCTCCTAGACAATTTCCTCCGACATCCTTAGCGACATCATTGTTTTCTAGACCATCTAGTCACCCTGATCCATTTCGTATGGAGCAACTAGTAAGTGAACGGTTTCGCTTAGGAGGACTTGGATTACCCCCGCCTCAAACCTTTTCTGACAGACCTTTAGTACCTCCACCCCCTCAGCGAGCTTCAGCCGTTCCTCCTCCACCTGCCTCGCTGCCATTATCTTTAGAACCTCAGTTAGACTTCTATTCCCAGCGCTTGAGGCAACTTGCAGGTACTACAAGCCCTGGACCCACAACGAGTTCCCCTTCGTCGAAGAAACATTCACCACCATTTACTAGTCCTCCTCCGTCCTATGTTCCTCAAACTACTCCTATCgttccaaataataataacaatttgtcaACTAGCAATAATAATCTTTCATCGCCTCCAACTTCTGAATCAACTACTATTGGTGATAAAACTTCTGACCCTCAAAATGATTCTGTAGATTTATCAACAACAGCTCCATTATCTTCGTCAACACCGCCTGCCAAAGCGACAGATCTCTCTATCGATTTGTCTATAAATTCTCATGAAAACGGCGATAAAATTCATCCTTGCGAATACTGTGGTAAGAAATTTCGTCACCAAAGTAACCTAGAAGTTCACAAGCGATCTCATACTGGCGAAATGCCGTACAAATGTTCAGTTTGTGATCACGCATGCTCACAGAGCTCTAAGCTTAAAAAACACATGAAAGTCCATCGACAAAAAAAGACATCCAACACTGAAGAAGACGGATCGAACGCTAATCCAAGTGGCGACCAAGTATCTAATGCTGGATCGGGTGACTCTGTAGACGAAGTTGAGGAAGAAGATGATGATGTCGATGAAGATGAAGATGAAATGGACGAGGAAGAAGATGAAGAAATGGACCTTGAAGAGGATGATGACGATGATGAAGATGGAGAAGCTCCAGAAGACCTTACTACTAAGTCCACATCCTCTACCCCTCCTAACAATACTCAGCCTAAGAGTGGAGGTAATAATAATGGTTCCCCTAAACCTTCATCTGGAAACTCTAAACCTCCATCTTCAGGATCACTTGTCGGTGAGCTTATGGATAAATTTGGGTTGAGTAATATTCAGCAGTATAACGATGCATATAAACAAGCTTTACAAGAATCGGTTAGCCATATTTCGAAGAAAGATGATTTGATTCACCGATCATTAATGTCCGACAACAATAACATTGGATTAAAATCAACTTTACCTCTTGGTAGACTAGACAATGGTCTAATTCAGAAAAGTGCTGCTATGCGATTTCGTGAAGAATTCGCTAAACTCTCCGGACAACAACCATTGGGTCTAGTTGGAGGACCGCATAATCTTTTTGGTACCGGCAATCCTTTTGAGCATTCATTTGATACTAGCAAAGGATTAAAAATGAGTTCAAAAGAAAGTAGTTATGGAAGATTATCTGGAGACAGAGACTTATACGCAGGTCTTTGGCTTCCAGCTATGGCTGTTGCTCATCATCGTGAATCAATGTTTGGAAATGGAGACTCTATTCCTGACATACTCAAAGGAGATAAACATAAAGATTCCAGTCATCCGGGCACCAGTGCTTCTTTAGCTGCTGCTGCCGCCGCCGCTGCTGCGCTCAACCTCGGAATGCCTGGCCAAATGAAGAAAGAATCAAGGCGTAATGATACCTGTGAATATTGTGGTAAAGTATTCAAGAACTGTAGCAATTTAACTGTTCATCGACGATCTCACACTGGTGAAAAGCCTTATAAATGCGAATTGTGCTCGTACGCTTGTGCACAGAGTTCAAAATTAACGAGGCACATGAAAACACACGGTAGAATGGGTAAAGATGTTTATAGGTGCAGGTTTTGTGAAATGCCATTCTCAGTACCTTCAACGTTAGAGAAGCACATGAGGAAATGTGTAGTTAACCAAAATATTAAAGTCGAGCACCATCTCATGCCTTCTGTCATCAGCACAGATGATGATTCCACTTCTGCAACGAAGGACTCCACATGA
Protein Sequence
MSHVVSKVVLTSDSDQGLEGAVNIRIPGEVRVGRVSIDLWGADLGEGEEEDVLTCGVCQKAFALADIVRFIQHKVKSCVNKENYLNCGEQSNGGGSGSGGESSELVRRPAPILGSAPSRSPDRCSTPKRRPRTPPTPPTPDPNLLIKQEHVDSSTPPHSSPDEGPCKKLRTDATSNTTNSEPSNYVCSTCKARMYSAWRLVQHVQNSHGMKIYVESAPSSSSSSGSSLTSSPGARHNSSSGSTSSASSSGPGPSTSSSSMVPTSLGLTSPLVDPHLPMHNPFAVSGLVRMPIEPPRQFPPTSLATSLFSRPSSHPDPFRMEQLVSERFRLGGLGLPPPQTFSDRPLVPPPPQRASAVPPPPASLPLSLEPQLDFYSQRLRQLAGTTSPGPTTSSPSSKKHSPPFTSPPPSYVPQTTPIVPNNNNNLSTSNNNLSSPPTSESTTIGDKTSDPQNDSVDLSTTAPLSSSTPPAKATDLSIDLSINSHENGDKIHPCEYCGKKFRHQSNLEVHKRSHTGEMPYKCSVCDHACSQSSKLKKHMKVHRQKKTSNTEEDGSNANPSGDQVSNAGSGDSVDEVEEEDDDVDEDEDEMDEEEDEEMDLEEDDDDDEDGEAPEDLTTKSTSSTPPNNTQPKSGGNNNGSPKPSSGNSKPPSSGSLVGELMDKFGLSNIQQYNDAYKQALQESVSHISKKDDLIHRSLMSDNNNIGLKSTLPLGRLDNGLIQKSAAMRFREEFAKLSGQQPLGLVGGPHNLFGTGNPFEHSFDTSKGLKMSSKESSYGRLSGDRDLYAGLWLPAMAVAHHRESMFGNGDSIPDILKGDKHKDSSHPGTSASLAAAAAAAAALNLGMPGQMKKESRRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRMGKDVYRCRFCEMPFSVPSTLEKHMRKCVVNQNIKVEHHLMPSVISTDDDSTSATKDST*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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