Basic Information

Gene Symbol
-
Assembly
GCA_944547385.1
Location
CALYMV010003999.1:124693-125478[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.00013 0.008 17.7 0.4 1 23 56 79 56 79 0.93
2 7 0.00065 0.039 15.5 0.4 1 23 85 108 85 108 0.97
3 7 8.1e-06 0.00049 21.5 0.4 1 23 114 137 114 137 0.96
4 7 2.4e-06 0.00015 23.2 0.2 2 23 144 166 143 166 0.96
5 7 0.00059 0.036 15.7 3.1 1 23 172 195 172 195 0.96
6 7 0.00015 0.0089 17.6 0.1 3 23 203 224 201 224 0.96
7 7 6.4e-05 0.0039 18.7 1.2 1 21 230 250 230 251 0.93

Sequence Information

Coding Sequence
ATGGACCAAGATATTGCCTGCAGTTTCAGTGGCATTATAATAAAGATAGAAGAAAACATAACAATCAAAACAGAGACTATCGATTATGAGGACGCAAGCGCAGAAGTTGACGATGGGCCTATACGACTTATAAAGCCGGAGCTGCCTGATCTTCAAAATGCGTCATTTTCATGTGACGAATGTAAAGGAGCGTTTACCATGAAGCGAAACCTGAAAAGGCACTTGGAAGCCGTTCACGGGAAGAGTAAATCATTCGTTTGTGGAGATTGCGATAGAGGATATTTTATGAAGGAGAAGTTAAAGTTGCATCTAAAGTCGGTTCATCAGAAGTGTCGAGCATTCTCCTGCGAAGAGTGTGAACGGGCCTTTTCCGAGAAAAGATCCCTGAACACTCACATGAAGGCTGTTCATATGAAGTTGAAGGATTTGATTTGTGCTGAATGTGAGCGTTCGTTCGCTTACAAATCAACTCTGAACAGGCACATAAACACAGTCCATTGTAATATTAGGAAATATGCGTGCGATCAGTGTAAACGTGCCTTTACGCACCTTACAAGCCTTAAGATGCACAAGGATACCTTCCACAAGAAACGAAAGAATCTCGCTTGTGTCGAGTGTAATCGGTCGTTTACGCGAGGTGCTTCTTTGAGGATGCATGTCAACACGGTACACCGCAATATTAAGAAGCACAATTGCGGAAAATGCGGACGTGCATTCGCttcaaaatataatatgaaaacgcATCAAACGACTTGTATTAAATCAAAGGAGTTTGGAAGGTCGTAA
Protein Sequence
MDQDIACSFSGIIIKIEENITIKTETIDYEDASAEVDDGPIRLIKPELPDLQNASFSCDECKGAFTMKRNLKRHLEAVHGKSKSFVCGDCDRGYFMKEKLKLHLKSVHQKCRAFSCEECERAFSEKRSLNTHMKAVHMKLKDLICAECERSFAYKSTLNRHINTVHCNIRKYACDQCKRAFTHLTSLKMHKDTFHKKRKNLACVECNRSFTRGASLRMHVNTVHRNIKKHNCGKCGRAFASKYNMKTHQTTCIKSKEFGRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-