Basic Information

Gene Symbol
ZFY
Assembly
GCA_944547385.1
Location
CALYMV010000610.1:15698-17059[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.02 1.2 10.8 0.1 2 23 132 153 131 153 0.97
2 11 8.1e-05 0.0049 18.4 0.5 1 23 159 182 159 182 0.96
3 11 4.2e-07 2.6e-05 25.6 1.0 2 23 196 217 196 217 0.98
4 11 0.00038 0.023 16.3 1.7 1 23 223 245 223 245 0.99
5 11 0.00013 0.0081 17.7 0.2 1 23 251 273 251 273 0.96
6 11 3.8e-05 0.0023 19.4 0.8 1 23 279 301 279 301 0.97
7 11 6.6e-06 0.0004 21.8 0.1 1 23 307 330 307 330 0.96
8 11 5 3e+02 3.3 0.5 2 13 336 347 336 354 0.77
9 11 0.00013 0.0076 17.8 1.4 1 23 360 382 360 382 0.98
10 11 1.6 99 4.8 1.7 1 23 388 412 388 412 0.80
11 11 0.0044 0.27 12.9 6.6 1 23 418 441 418 441 0.97

Sequence Information

Coding Sequence
ATGGCTGAAAAACTGCATTCTATTAATATGCAAGAGGCGTGCAGAATATGCTTATCGGACGACTGCTTGATAACAAAACAACCAATATTCGAAACTACGAATGGACCAATCAAAGAAGATGCGATCAAGTACTGTGGAATTCTATTAGAAGAAAAGAAAGGTCTTCCTACAATGGTATGCTCCGAATGCCTCTCAAGTTTGTACGCTGCAGTTTCATTCATCGAGAAATGTAGAGATACAGAGCTGTTGCTGAATGAGTATGCGAAAGATTTAGAGATAAAGGAGGAGCTCGACTTTGATTATTTCGAAAGCGTCGATTGCCTCGTCGATGATTCCGATATTAAAACAGAGACTGAAccgttaaaattaaaaaaaaagaaatccatGGCGCTGCAGTGTGTCACCTGCGGCGCGTTCGTACAGAGTCAGTCCGCTTTAGTCAATCACAACCGAACGCATACGGGCGAGAGACCATTCTCGTGCGCATCGTGCGGTAAAAATTTCGCGCAGAAATCCACAATGCGCCTGCATATCTTACGCGTCCATTTGAAACATCGCAAAGTACAGAAAGTCGCAAAATCAAACACGTGCGAAGTGTGCGAAAAGAAGTTTTCGTCGTCGACGAATCTGAAAGTGCACATGCGAATCCACACGGGGGAAACTCCGTACGAATGCGACGTATGCTTCAGACGGTTCATGCAGCTCGGCACGCTGACGAGTCACAAACGAAGACACAACGGTGAAAAGCCGTACGCTTGCGGCGCCTGTGGCAGGGCCTTCGTCGAGAAGAACCATCTAATCAGACACCAGAGCGTGCATAGCGAGGCGAAACCTTACACTTGCAGCATTTGCAACAAGAGCGTCAAATCCTCCTTCGCGCTGAAGCAACATGTTAAAGGGCACGCCAATTCGAAAGATCACATCTGCGACCAGTGCGGTGCCTCTTTTACAGTAAAGGGCAATCTCGTAGCGCACATGAAAGTGATACACTCGGCGAAATCAGGCCAATGCTTGATCTGCAACAAGATATGCTCGGATCTCGGCGAGCACATGATTGATCACACGGGCGAGAAAAAATATGAGTGCGTGCAGTGCGATAAGAGATTCGCGCACAAGCGTGGGCTGATTGTGCACAGCCGCCAGCACACGGAGAATCACAGGTTTCAGTGCTCGTTCGAAGGGTGCGATAGGACGTTCTACGCGCAGTGGCTCTTGGACTGCCACGTGTCCAAGCACACCGGATGTACTCCGCACGTGTGCAAATTCTGCTCGAAGGGATTCTTGCGGTCGTAccatttaaataaacatttgaaGACGAATCATGCTCTGGTTAGTAACGAGTTTGGCGGATCTGAAGGATGA
Protein Sequence
MAEKLHSINMQEACRICLSDDCLITKQPIFETTNGPIKEDAIKYCGILLEEKKGLPTMVCSECLSSLYAAVSFIEKCRDTELLLNEYAKDLEIKEELDFDYFESVDCLVDDSDIKTETEPLKLKKKKSMALQCVTCGAFVQSQSALVNHNRTHTGERPFSCASCGKNFAQKSTMRLHILRVHLKHRKVQKVAKSNTCEVCEKKFSSSTNLKVHMRIHTGETPYECDVCFRRFMQLGTLTSHKRRHNGEKPYACGACGRAFVEKNHLIRHQSVHSEAKPYTCSICNKSVKSSFALKQHVKGHANSKDHICDQCGASFTVKGNLVAHMKVIHSAKSGQCLICNKICSDLGEHMIDHTGEKKYECVQCDKRFAHKRGLIVHSRQHTENHRFQCSFEGCDRTFYAQWLLDCHVSKHTGCTPHVCKFCSKGFLRSYHLNKHLKTNHALVSNEFGGSEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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