Basic Information

Gene Symbol
-
Assembly
GCA_944547385.1
Location
CALYMV010005291.1:121905-122936[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 1.6e-06 9.5e-05 23.8 1.9 1 23 11 34 11 34 0.95
2 11 0.00021 0.013 17.1 0.1 3 23 57 78 56 78 0.92
3 11 7.2e-05 0.0044 18.6 0.7 1 23 84 107 84 107 0.96
4 11 0.011 0.66 11.7 0.1 1 23 114 137 114 137 0.94
5 11 7.9e-06 0.00048 21.6 0.1 1 23 143 166 143 166 0.96
6 11 0.0023 0.14 13.8 0.0 1 23 172 195 172 195 0.97
7 11 1.8e-07 1.1e-05 26.7 0.1 1 23 201 224 201 224 0.95
8 11 4.2e-08 2.5e-06 28.7 0.5 1 23 230 253 230 253 0.97
9 11 0.00024 0.015 16.9 1.0 1 23 259 282 259 282 0.96
10 11 0.00061 0.037 15.6 3.3 1 23 288 311 288 311 0.95
11 11 4.4e-05 0.0027 19.2 0.9 1 23 317 340 317 340 0.95

Sequence Information

Coding Sequence
ATGGCTTCTCTCGCCAAGCTGCTCAAATCGTACATCTGCCCGAAGTGCCATCGCGTTTTTTCTAACAAAAACGAAATGAAAAAACACATGAATGCCGATCACATAAAATTTAATTCCGTTTGGCGCAgcgacagaatcgtcgatcgaAAAATAAGCAGGAATGTTGCGTGTGGACAATGTGACAGGGCTTTTCGCGGCCAATCGCAGCTGAAGGAGCACATCGACGCTGTCCACTTGAAACTGAAGAAATTTGTCTGTGAGGAATGCGGCTACGCTTGTTCGTTTAAGCGATCGTTGAATTCGCACATCGAATCCGCTCATAGCTACGCTTTGAATAAATACGCGTGTGCTGAATGTGACAGCGCTTTCGTGCAGGAGAGAAAATTAGAGCAACACAAGAAAGATGTACATTTGAAGTCGAAGGTGTTCGTTTGCGGAACGTGCAATCTTTCGTACGCGAGAGAAAGTAATCTAAAAAGACATATTGAAGTCGTTCATATGAAATCAAAGGAATTTATATGTGACGAGTGCGCCCGTCCTTTTATAGGACAGAAGAGCTTGAGTATGCATATAGAGACCGTTCACCAGAAGTTGAAGAATTATTTGTGTGCCGAGTGCGGCAAGGCGTTTTCCCAAAAAGGAAACTTGAAGGAGCACATACAGACGGTGCACTGGAAAGAAAAGAAGTTCGTCTGCGACGAATGCGGTTATGCTTTCACAAGAGAGAGCAATTTGAAGAAACATTTGAAGTCCGTTCATCTGAAACTAACGAAGTTCGTGTGCGACGTGTGCTTTCACGGTTTCACAGAGCGAGGATCTCTGAAGCGGCATCTACGTGACATCCACGGCAAAATCAAGGTCTTTACTTGCGGTCGTTGCGGTCTCACGTACTCCACGCGACAACATCTGGAAACGCACTTGCATTTAGATCATCAGAAACTGAAGACGTTTTTCTGCGGACAGTGCTTCAGGGCTTTTAGAAGCCGAGCAGACCTAACTAAGCATCTGAGGGAAATTCACCCGGCGAAGTAG
Protein Sequence
MASLAKLLKSYICPKCHRVFSNKNEMKKHMNADHIKFNSVWRSDRIVDRKISRNVACGQCDRAFRGQSQLKEHIDAVHLKLKKFVCEECGYACSFKRSLNSHIESAHSYALNKYACAECDSAFVQERKLEQHKKDVHLKSKVFVCGTCNLSYARESNLKRHIEVVHMKSKEFICDECARPFIGQKSLSMHIETVHQKLKNYLCAECGKAFSQKGNLKEHIQTVHWKEKKFVCDECGYAFTRESNLKKHLKSVHLKLTKFVCDVCFHGFTERGSLKRHLRDIHGKIKVFTCGRCGLTYSTRQHLETHLHLDHQKLKTFFCGQCFRAFRSRADLTKHLREIHPAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-