Mman003226.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Microplitis manilae
Gene Symbol
L
Assembly
GCA_030273425.1
Location
CP092721.1:5513727-5521929[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.3e-06 0.00019 22.7 1.1 1 23 99 121 99 121 0.98
2 16 0.56 86 5.0 3.9 1 23 127 149 127 149 0.97
3 16 2.3e-06 0.00035 21.9 2.5 1 23 155 177 155 177 0.99
4 16 9.5e-05 0.015 16.8 0.8 1 23 183 205 183 205 0.98
5 16 0.12 19 7.0 0.1 2 22 385 405 384 407 0.86
6 16 0.51 78 5.1 0.3 3 23 445 465 444 465 0.96
7 16 0.0084 1.3 10.7 1.2 3 23 479 499 477 499 0.96
8 16 0.0069 1.1 11.0 2.6 1 21 511 531 511 534 0.90
9 16 0.069 11 7.8 0.2 1 23 539 562 539 562 0.92
10 16 5.2 8.1e+02 1.9 0.1 9 23 595 610 593 610 0.87
11 16 0.032 4.9 8.9 4.8 2 23 660 681 659 681 0.97
12 16 0.0031 0.48 12.1 0.1 1 23 686 709 686 709 0.95
13 16 0.06 9.3 8.0 1.6 3 23 812 834 811 834 0.94
14 16 8.4e-05 0.013 17.0 0.7 3 23 855 875 853 876 0.94
15 16 0.15 23 6.8 0.1 2 22 887 907 886 909 0.84
16 16 0.01 1.5 10.5 0.4 1 23 1227 1250 1227 1250 0.95

Sequence Information

Coding Sequence
atgttatttaaggGAAATAGTTCAagattagaatttttaattgaaaaaattcaagcgCATAAAGAACTATCGCCGTCACCGCTTCCAGATGACAAGTGTACTTTAAGATCAAGagAAGGTCTGTTGAGTGGAATTTACTCATGGCGTAGCGAAGACGACAGTCTTAATGGACAGAGAGGTGGTGGGACACCATCTTCTTGCACAACTTCGACGTCGCTGAGTTTCCCCTCGGAAACTGAGACTGATGTTgacgttaaattaaatagtatCGACAGCAGCATCACTTCTGGCCCATACCCGTGCcaattttgtgataaatctTTTCCCAGTTTGAGTCAGCTGAAAAAACATGAACAGacTCATGGTGATCAAATGCCGTATCGTTGCAGCTGGTGCGCGCgattatttaaacataaaCGCAGTAGAGACCGTCACGTAAAGTTGCATACCGGCGACAGGAGATATCGATGTACTCGATGTGAAGCTGCGTTTTCTCGCAGcgaccatttaaaaattcacatgAAAACTCACGATAATCAGAAGCCATATCACTGCAGCGAATGTTCGCGGGGTTACAATACAGCAGCAGCATTAACGTCGCACATGCAGTCCCACAAGCGTCCTCACTCAttacaattacaattaaataatcatcTCTACTCATCCCCTAAAACCGGCGAGACTGAGCGCAATTCGCTTTGGGCAAGTCGGGGATCTTCGCCTAGCGTTAGCTCACCGTTACCTTTGTCATCCTCAATGTCTATGCATAAATTAACATCCTATTCACCAGACTCTTCAGCCAACGAGTCATCACCCGCAGTATCCTTCTTACGGTCGTCATTAACACTCGCCTGCATGTACTGTGCCAAAGATACGTTTACCAGCATGGAACAGCTTCAACTGCACGTTCAAGCTGTCCACGAGCTCAACATAAACAACAATCCGCTAAATAATCTAAGCAGTCCATCGTCATCGCCATCAACAGCAACGGCAACGTCAACGTCAAATAAAATAGTAGACAATAACTACAAGcgtcgtaaaaaaaaagaagactTTAAATCGAAAGATGATCACACTAAAGTACATCGcagtaataatgataaagttgctattaataataacaatgacaCATCAGTATCAGCGTTGATGTTAACGTGTCCTTTGTGTGGGATATCATGTTCGTCCCCGACAGTCTACGCCGAGCATTACGTGCTCGAACACTGCGAAAATCGTAAAGTTGTTGCTGATAAAATGActgatgacaaaaaaaattatgaaaaaaaaatgatgagtaACTTGACTGCAGACGTTTATTCCTCAAGTACTTTATTGTGCGGGCAGTGCGGCGCGGCATTGAAAGACTTTGAGTCCTTTCGTGTTCACTTGGCGCatcatttgaaaataaacaattaccagAAGCAATTAAACGTCAATTGCCCAAAGTGTGAACTGAATTTTCACACCCAAGATGAGATGATTAATCATCTGACGAAGCACTACTTGAATGATAGTAATATAATTAAGCAGCGTTACTGTTGTGATGGATgcgataaatattattttgacgCGGAGTCGCTTAAAAAGCACACGTTTGATGAGCATACGCAGCAATTGTACAGATGTGCTGTTTGCAGAGAGACCTTTGAGTCGTCAGTCGCTATTCAAGTGCATTTCACTGTTAAACACACACGAGAGTGCACTGTTTATCAATGTACTGACTGCATAAATAATCCAGGGCGCGCCAAGAGTAATGAGACGCGGGACAACAATGGGGtggattgtttttttaaaacttgtacGGAACTGATGAAACACGTGATTAATGCTCATTTATCGTCCTCGTCATTATCCTCGTCGTCATCGTCATCATTGTCCTTGTCATTGTCGTTATCGTCTGCGCAAGAACAAGATCGAATTACTCAAATGAGTTGTGGAATCGCTCAAGACACAACGAGAGTCTGCGgtgaattatttttacgatGCTGTTTTTGTGGTGTACATTGTAATACAGAGGGTGATTTACAACGACACTTGGCAACCCACTCGACGTGCCTTTATAGATGCCCGATTTGTCGTCAAGGTTTTACTGTTGAATTTTTGCTGGACAAGCACATTGCTCAGATACATAACAATAATTCAGcggctgctgctgctgctgttgatAGTGTCCCTgctactgctgctgctgctgctgctgctgataCTATGATAGATAGACATAATATTGTTAATCATTATAAAGTACAAGATGAGATGAGGTATAAAAGAAAACATTCATCGCCTGAATTAATACAACAAAATCAATCAGATCATTGTTTATCAAACCgtccaaataataataataataataatgataataataatactaataataataatattaatataaataataataatagtgataataaaaatgaattaaaaataaatcactgTGAATATTGCGATCGGAAAGATTTTACAAGTGACTCAGAGTTACGCGCGCACAAAAAACTTGCCCAcaaatcatcatcatcatcgttaGCAAAAGTCAATCAAACAAAATCGTTATCACTGCAAATCTGTAGTTACTGCGGTGAATCAACGCGTTCACGTGGTGAATTAGAAGCTCACACAAGATTGCACCACGCGCCGAATGAATCAGCAAAGCGTCGTTTAAAGTGTAACATTTGCGATGAATTATTTTCGACAAGTGGTATTTTAGCAGAGCATAAATTAGACAAACattgcaaaataaaattgagcgACGTGTGCATCGTCTGCAGAGTCGTGCTACAAAGTGAAACAGATTTTATTGAACACGTACAGAAGCATAGTTTAGAATCGATTGATTCACATCAACAGAGACACGATGGTTTACTTTCAGCTCCTATTTCAGCAACAACTCAAACAGTTTCTCTTCCAACTAGTACTCTTACTCCTAACTCTAACACTAGTACCAATACTAATACTAATACTAGTTTTAGTTTTAGCACCAGTATTAGTATTACAACTTCTGGCAGTACTCATGTCCCCGTTTATTGTGTTGTCTGCAGGCAGACTCTCATTAGCGAGTTCGATTGTCAATTACACGCCAAGTATCATTTACGATCACAATCTTCACTTGATTCTAATTTTATTcctgttaataataataataataatagtaaattaaattgttgcatttgtttacgagaatttgataatgataattcTGTTATACCTTTGGCAGGAAGTAGTTATGATATAGCAATTAGTGAACGTAAATTGAATGTCTGCAACAGATGTTACGTCAGACATTTGAACGGCTTGCCTATTTtaggtaataatttttataataataatgataatgatgatgataaatttataaatgaaaatgctGATCATGGTGATGTTGATAATGAATATGAGACAAAGTGTATTAAATTAGAGAGTATGAATGATAATgaagatgataataataatgataatgataatgacaacgatgatgatgatgatgaagatgaagatgaagatgTTAATGTGGATGTTGATGTTGACGTTGATGTTAATAATGAGTATGAGGGGCTGGGCAAAGAGAAAGATGATAAACAAGGAGAAAACAAAGTGGAGGATAAGGAGGATGAGAATAAGAAAGGAGAGAATGATAAGAATAGTGTTTGTAATGATAAGAATAAAAGTAGTGCTGGCGTCCGTCCATATAACTGTCCTCAATGTACCCTCTTGTTTGCTTTTAAAGTTGAATTGGAGCATCACCTTAATGCTGtacatatgaataaaaatatgtcttgTATGGTTAATGCTACACCGAGggagaataaatttattaaagtagTTGGGAATTATCCTGATGGTAATGTGAAGGACAATGTGAGCGAACAAGAGGGTGAGGTTGTTGTAAAAGAAGAAGTTGTTAATAATGAGCCcactaatgattttaaaaaAGATCTAAAGACTTTTTCAGACAAAAATCCGGAAAATTTCCACCAGGGAAACTAA
Protein Sequence
MLFKGNSSRLEFLIEKIQAHKELSPSPLPDDKCTLRSREGLLSGIYSWRSEDDSLNGQRGGGTPSSCTTSTSLSFPSETETDVDVKLNSIDSSITSGPYPCQFCDKSFPSLSQLKKHEQTHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTRCEAAFSRSDHLKIHMKTHDNQKPYHCSECSRGYNTAAALTSHMQSHKRPHSLQLQLNNHLYSSPKTGETERNSLWASRGSSPSVSSPLPLSSSMSMHKLTSYSPDSSANESSPAVSFLRSSLTLACMYCAKDTFTSMEQLQLHVQAVHELNINNNPLNNLSSPSSSPSTATATSTSNKIVDNNYKRRKKKEDFKSKDDHTKVHRSNNDKVAINNNNDTSVSALMLTCPLCGISCSSPTVYAEHYVLEHCENRKVVADKMTDDKKNYEKKMMSNLTADVYSSSTLLCGQCGAALKDFESFRVHLAHHLKINNYQKQLNVNCPKCELNFHTQDEMINHLTKHYLNDSNIIKQRYCCDGCDKYYFDAESLKKHTFDEHTQQLYRCAVCRETFESSVAIQVHFTVKHTRECTVYQCTDCINNPGRAKSNETRDNNGVDCFFKTCTELMKHVINAHLSSSSLSSSSSSSLSLSLSLSSAQEQDRITQMSCGIAQDTTRVCGELFLRCCFCGVHCNTEGDLQRHLATHSTCLYRCPICRQGFTVEFLLDKHIAQIHNNNSAAAAAAVDSVPATAAAAAAADTMIDRHNIVNHYKVQDEMRYKRKHSSPELIQQNQSDHCLSNRPNNNNNNNDNNNTNNNNININNNNSDNKNELKINHCEYCDRKDFTSDSELRAHKKLAHKSSSSSLAKVNQTKSLSLQICSYCGESTRSRGELEAHTRLHHAPNESAKRRLKCNICDELFSTSGILAEHKLDKHCKIKLSDVCIVCRVVLQSETDFIEHVQKHSLESIDSHQQRHDGLLSAPISATTQTVSLPTSTLTPNSNTSTNTNTNTSFSFSTSISITTSGSTHVPVYCVVCRQTLISEFDCQLHAKYHLRSQSSLDSNFIPVNNNNNNSKLNCCICLREFDNDNSVIPLAGSSYDIAISERKLNVCNRCYVRHLNGLPILGNNFYNNNDNDDDKFINENADHGDVDNEYETKCIKLESMNDNEDDNNNDNDNDNDDDDDEDEDEDVNVDVDVDVDVNNEYEGLGKEKDDKQGENKVEDKEDENKKGENDKNSVCNDKNKSSAGVRPYNCPQCTLLFAFKVELEHHLNAVHMNKNMSCMVNATPRENKFIKVVGNYPDGNVKDNVSEQEGEVVVKEEVVNNEPTNDFKKDLKTFSDKNPENFHQGN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01006569;
90% Identity
iTF_01004603;
80% Identity
-