Basic Information

Insect: Microplitis manilae
Gene Symbol: Zbtb8a
Assembly: GCA_030273425.1
Location: CP092721.1:24826929-24828938[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1.8 2.8e+02 3.4 0.7 1 13 198 210 198 216 0.81

2 10 2.9e-06 0.00045 21.6 0.2 1 23 366 388 366 388 0.98

3 10 0.00073 0.11 14.1 0.6 1 23 394 416 394 416 0.94

4 10 2.3e-05 0.0035 18.8 0.5 1 23 421 443 421 443 0.98

5 10 1.3e-05 0.002 19.6 0.5 1 23 449 471 449 471 0.98

6 10 1.4e-06 0.00022 22.6 1.8 1 23 477 499 477 499 0.98

7 10 0.0013 0.2 13.2 0.1 1 23 506 528 506 528 0.86

8 10 0.0016 0.25 13.0 1.1 2 23 535 557 535 557 0.97

9 10 0.00034 0.052 15.1 2.1 1 23 563 585 563 585 0.97

10 10 3.2e-05 0.0049 18.3 1.1 1 23 591 614 591 614 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1.8	2.8e+02	3.4	0.7	1	13	198	210	198	216	0.81
2	10	2.9e-06	0.00045	21.6	0.2	1	23	366	388	366	388	0.98
3	10	0.00073	0.11	14.1	0.6	1	23	394	416	394	416	0.94
4	10	2.3e-05	0.0035	18.8	0.5	1	23	421	443	421	443	0.98
5	10	1.3e-05	0.002	19.6	0.5	1	23	449	471	449	471	0.98
6	10	1.4e-06	0.00022	22.6	1.8	1	23	477	499	477	499	0.98
7	10	0.0013	0.2	13.2	0.1	1	23	506	528	506	528	0.86
8	10	0.0016	0.25	13.0	1.1	2	23	535	557	535	557	0.97
9	10	0.00034	0.052	15.1	2.1	1	23	563	585	563	585	0.97
10	10	3.2e-05	0.0049	18.3	1.1	1	23	591	614	591	614	0.93

Sequence Information

Coding Sequence: ATGGTCTGCTTGTCACTCCCGgtgtaTGACGGCGATGGATTGCCAAACAAAGTTTGTATTCCTTGCAAAGACGAGGTAACTAAGTTCTATTACTTTCGTAAAAAATGTCTGAGGACGTATAATTCATTAGTGCAGGAATgtcttgataaaaataattattctttggTAAATAATGCAGTAGTTGAAGCAAAAGATGAACAAGAGGAAGTAATTGATGAAGAGTTTATCGATAGTGGCTTTGAAGAAGCTGTTAAAGGATCAGAACTTGCAGTCACAGATTCAGAGATTAtttttgatgataataaaactGGAGATGGAGATGGAGACGGAGATGAGGAGGAAGTAGTTGATGAAGAGTTTATTGATAGTGGCTTTGAAGAAGCTGTCAAAGGATCAGATGTagttttagaaaatatttataatgatgaaaaaGCTATAGATGAACACGTTGATGAAGAATATTTGGGTAACAATTTAGAACATATCAACGAGTCTGAATTAAAAGTAGACAATTCTGTAAATTCCAATTTACTGGAGAGTGGAGCGGAAGCTTGTGCTTTGGAAAAGAATAAGAAAAGTATTCTGAAAGAATACAAATGTTTTTATTGCCAGTCGGTGTTTGATAGTTACAATGGAGCTGCTCAGCACTGTATTGAATGTGTCGGGTCTAAACAGCTTGCAAATGGACAGGATGAAGCTTCAGAGGACGACTGTAAGGATGGAGATGAGTTGTATTCAGACTATGAATTTATGGAGATCTTGGACAGCGAAAATAATGAGGCCAAGGATTCAGGTGATGAGGTTGAGTTCATTGAAGAAGCGTATTGTGATAGTGAGGAGTCGGAGGCTAAGGATCAAGATACTGGTCAAGAAATTGGAGATACTGATCAAGTGAAAGCAGAAGCTGGTGAAGAaggaattttaattgaaaaaattgatgatgAATACTTGGAACCGGGTGATGAAATTAATTTGGatagagataaaaataaagatcctGATTTACTGctaggaaaaaataaatctgattCTCAACCGAGTACACAAGTGCGGACCAAAAGAATTTATCGTAAGAGAAAAGTATATCCAGATAATTATCCATGTCCTGAATGTAGTAAACCTTTCGCATCTAGAAGTTTAATGAAACGTCATTACTTAATCCATACTGGCGAGCGTCCTTATGTGTGTGATACCTGCGGGAAACGTTTTTCCCAAGTAGGGGCTTTGAATTTCCACAAAAAACTCCACGTGAACCCACCGTACCGATGCAAAACCTGCGGGAAACCGTTCATGCGCCCCAGTGACATCGACAAACACTCGCGAATTCACACGGGAGAAAAACCATTCACATGCCATATCTGCGGTAAGAACTTCGCCCAGTTGGTGGCCGTCCAGCAGCACGAAAGAATCCACACTGGAGACAAGCCTTATCAATGTAATATCtgtgggaaatttttttctcaaaacgCCAACAAGAAGAAGCACGAAAAGATCCATCAGAAAGGCGCGAAACCTTTCGTCTGCGACATATGCGGCCGTAGTTTCTCCGACACCGTGGAGATGGGACTCCACAAGGCCGGTCACGGAGGAAAAAAAGCCCGGCAGTGCGACTTTTGCGGTATGCGGTTCAAAAAGTTTTCCGAGGTTGCTAGTCACGTAAGAAGATTTCATACTTTCGAGCGGCCTCACACTTGCGAATTTTGCAGTAAAGCTTTTTATTCGATCTACAGTTTGAAGCAGCACGTCATGATCCACACGGGACAGAAACCATTTGCTTGCAGTGAATGCAATATGAAATTTACTCAGAAAGGAAATTTAGCTAAACATTTTGCAAGGAAGCatcctgataaaaatttgaaagataCCAAAagtgttaataataatgacaatagcAATAAAGAAAGTGATGAAAATTCAGCAGATAAATCTAGTGGTTGA
Protein Sequence: MVCLSLPVYDGDGLPNKVCIPCKDEVTKFYYFRKKCLRTYNSLVQECLDKNNYSLVNNAVVEAKDEQEEVIDEEFIDSGFEEAVKGSELAVTDSEIIFDDNKTGDGDGDGDEEEVVDEEFIDSGFEEAVKGSDVVLENIYNDEKAIDEHVDEEYLGNNLEHINESELKVDNSVNSNLLESGAEACALEKNKKSILKEYKCFYCQSVFDSYNGAAQHCIECVGSKQLANGQDEASEDDCKDGDELYSDYEFMEILDSENNEAKDSGDEVEFIEEAYCDSEESEAKDQDTGQEIGDTDQVKAEAGEEGILIEKIDDEYLEPGDEINLDRDKNKDPDLLLGKNKSDSQPSTQVRTKRIYRKRKVYPDNYPCPECSKPFASRSLMKRHYLIHTGERPYVCDTCGKRFSQVGALNFHKKLHVNPPYRCKTCGKPFMRPSDIDKHSRIHTGEKPFTCHICGKNFAQLVAVQQHERIHTGDKPYQCNICGKFFSQNANKKKHEKIHQKGAKPFVCDICGRSFSDTVEMGLHKAGHGGKKARQCDFCGMRFKKFSEVASHVRRFHTFERPHTCEFCSKAFYSIYSLKQHVMIHTGQKPFACSECNMKFTQKGNLAKHFARKHPDKNLKDTKSVNNNDNSNKESDENSADKSSG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01006513;
90% Identity: iTF_01003751; iTF_01004546;
80% Identity: -