Basic Information

Insect: Microplitis demolitor
Gene Symbol: PRDM10
Assembly: GCA_000572035.2
Location: NW:92786-97956[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8.2 5.9e+02 0.6 0.0 5 16 537 548 535 550 0.89

2 14 3.3e-07 2.4e-05 23.9 2.9 1 23 593 615 593 615 0.98

3 14 0.0046 0.33 10.9 1.9 1 23 624 647 624 647 0.97

4 14 0.00022 0.016 15.0 1.1 1 23 664 686 664 686 0.98

5 14 2.9e-05 0.0021 17.8 0.1 3 23 706 727 705 727 0.95

6 14 0.00038 0.027 14.3 3.1 1 23 759 781 759 781 0.97

7 14 0.91 65 3.6 4.6 2 23 790 811 789 811 0.96

8 14 0.0011 0.077 12.9 0.3 1 23 818 840 818 840 0.98

9 14 0.00012 0.0085 15.9 4.0 1 23 847 869 847 870 0.95

10 14 0.00077 0.055 13.3 2.4 1 23 875 897 875 897 0.98

11 14 2e-05 0.0014 18.3 4.1 1 23 903 926 903 926 0.96

12 14 0.0014 0.099 12.5 1.7 1 23 982 1005 982 1005 0.97

13 14 3.1e-05 0.0022 17.7 2.4 1 23 1027 1050 1027 1050 0.97

14 14 0.0013 0.089 12.7 3.4 2 23 1090 1112 1089 1112 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8.2	5.9e+02	0.6	0.0	5	16	537	548	535	550	0.89
2	14	3.3e-07	2.4e-05	23.9	2.9	1	23	593	615	593	615	0.98
3	14	0.0046	0.33	10.9	1.9	1	23	624	647	624	647	0.97
4	14	0.00022	0.016	15.0	1.1	1	23	664	686	664	686	0.98
5	14	2.9e-05	0.0021	17.8	0.1	3	23	706	727	705	727	0.95
6	14	0.00038	0.027	14.3	3.1	1	23	759	781	759	781	0.97
7	14	0.91	65	3.6	4.6	2	23	790	811	789	811	0.96
8	14	0.0011	0.077	12.9	0.3	1	23	818	840	818	840	0.98
9	14	0.00012	0.0085	15.9	4.0	1	23	847	869	847	870	0.95
10	14	0.00077	0.055	13.3	2.4	1	23	875	897	875	897	0.98
11	14	2e-05	0.0014	18.3	4.1	1	23	903	926	903	926	0.96
12	14	0.0014	0.099	12.5	1.7	1	23	982	1005	982	1005	0.97
13	14	3.1e-05	0.0022	17.7	2.4	1	23	1027	1050	1027	1050	0.97
14	14	0.0013	0.089	12.7	3.4	2	23	1090	1112	1089	1112	0.96

Sequence Information

Coding Sequence: atggATCCAAGGGGCCCTCAAAGAGCGGGGGCCCCTATAAACCCAACGACAATTACATCAACAATATCAGATGTTAATTCAGCTGTTGATAAGTCACTGCTGGATACTGTTGTTGATGACAATTGGCATGGAGTTGGTAATAcagctaaaaataataaccgtTTGTTGTTCCTCACTgttgAATATGTAGACGATTATCAGTCACGAGACTATTCAAAGGTATTTTCTCCATACGAACAGGTGTCTTTTTATTCCCCGAGAGCTCCGTCACCTCTCTCAGACTTTGAGCACAGCAAAGTGAGCCCACTGGACCCGAACATGAGTTCAACTGCAAGATATTCACCTACACCTGTACAACAGCTTCCATCTCTGGCATTTCCAAACTCCGTAGTAGTTCTTCCTGGTCCTCCTTCACCGCTTATTATTCCTAGTGACGGTCATGCTAGagtcaatattaataattatatttctagTCACAATAATACTATTCAAAATGTAGCACAGTCGGGGGATAGTGCAACAAttgattttgtaaataatgagGCTCATGGAGAATCTCTAGTTACTAGTGTTAATGGagagttaattttaatgcAAGGAACAAGTACTGAGTTGGAGTCAACTTCATCGTCTTCGTCTTCGGTGTCAGCTGACACTGCTGCTGCCGGACCGCTGATGCTGGCAGAAATTCCAGAGGCTGAGTTTGCATTGACCCGAGAATTTTTGGTGATGCAAGATGATGACCATTTAAATGTCGTTAATTCATTGCCCAATCaaaattgtgaaataaaagAAGAGCAGATTATGATTACCgatgataatattattgataatcatCAAACggaattattgaatttaaataatggaaaTGGAGTAATTTCTCAGGAACAAGTTttaggaaaaatattaaaaaataatattgaatgtaaaaaattaataaaaaatattccagcTTCTGGTAAAATAACattgaggaaaaataaaaaacaaattcgtAATAAAACAACTttagAATGCGAGGAGTGTATTTCAGCAGCTTGTTTGAAATCTGGTGAATGTACCTGTCGAAATGTCCGCACAATTGCTGATCAACCGGTACCATCTCGAGCTGTTGCAACTTTACCAGGATCGTATCttgcgataaataaattactatcgGCTACAGCTATTGGTGAACCAATAGGACAAAGTAATTATGGAGTATTTGCTAAACGTAATATTCGGCAACGCACTCAGTTTGGGCCTATCGAAGGTATACTGCGTCCTTACAACGGTgagtttcttaaaaataatggaCTACCTTTGCTTTATGAAACAAATGACGGGCAGCTACTAAAAGTTGACGTGTCAGACGAAAATACTTCAAACTGGATGCGATTTGTTCGACCGGCTTTGACTTTCGATGAACAGAACTTAGTTATTTGTCAGCAGAgtgatggaattttttttcttaccacCCGAAATATTCTATCTAAAGAGGAATTGAAAGCAGGTCCAAGTTCTCAGTATGCTCTACGTCGCAATTTGACTGTTCTTCAACCAGGCTCATTGTTGAAAGACAAAGAAATCCATCAGGATGACAGTAATATTAATGGATGGCCGTATTTGGAGTGCGACGAGCCATTCAAATCATCTGAAAAGTTATCAGAACCTTTAGATGCTCATCAAGATAAAAGTGaagcaactgaaaattttgaaagccaacaaaataattcaaaattgtcgtctgacgataataataaatcacttaaaGTTGTTGATGGACAAACGGTCCTCTATTCCTGTTCTCAATGCCCAAAAGTATTTCCACGAAGTTATAGTTTGAAGCGTCATATGCACATGCATCTTGGCTCAAAAGCGCCGCAGAAGTATGAGTGTTCAACCTGCGGCGAGAATTTTTTGCATCCTTACAACCGCAGTcggcatataaaaatatttcacagTGACGAAACACGAGAGAAAGAAAATGCTCGTGAAAGTTCCAgtgaatataaatgtaaatctTGTAATTtggcttttaaaaaattgtctttgtTGAATATTCACAAATTAATACACGAGCAAGATGTAAATAAAGAACACGATGGTTCTTCAACATCGTCATTGTCATCGGCATGTCCACAGTGTGGAGTTACATTTAATACTTGGTACGATTTAATAAATCACGTATCATCAAAACATGGCCGGATTAAGTTGCCTAAAGTAACTAGTACATCTaaagtaaacaataataataataatcaaaatcaaaatcagGTTTCAACTCCACCAATGTATAAATGTACAAAGTGTTACAAACGTTTTGCAACAAAGGTACGACTCCAGCAACATTTTCTAGTCCATGGCGCTGAGGATCAAAAGCCACTGCCGTGTAATGTCTGTTGTAAaagatttatgaataattcagCACTCTCTTGTCACTTGAAAACTCATCGTCAGGATAAACAATTGTTTGAGTGTCCAATGTGCCGTAAATTGTTTAACCAAGTTCTCATGCTGAAAGAGCACATTGAAACACACAGAGGTGAGGATGGTATATTTAGTTGCCCTCACTGTCCGAGGACATTTACCAAGTACTCAGTTATAAGGAAACATATCAGAGCTCATCATTGTGAACGTAAACACAAATGTCAATTTTGTTCTAAACCATTTCCGACGATTGACAAATTACGTATGCATTTATTGCGTCACTCGGATCACAGGGAATTTCATTGTGCTAATTGTGGAAAGCAGTTTAAGCGTAAAGATAAGTTAAAAGAACACATGACGAGAATGCACAATGCACAGAAAATAAAGCGGGATCAAATTACAACacaaaatagtaataataataataataataataatgataatattagtaataataataatgataatgataataatagtcaggggaaaaaatttgtaccaAAAGTTAATCCGACGGATTAcaatcgttttatttataagtgcCATCAATGCCTAGTGGGTTTTAAACGACGAGGAATGCTCGTAAATCATTTGGCTAAACGGCATCCCGATGTATCACCGGACTCTGTTCCGGAGTTGAATTTACCCATTTTAAGACAAACCCGTGATTACTATTGTCAGTACTGTGATAAAGTTTACAAAAGTAGTAGTAAGAGAAAGGCGCACATTATGAAAAATCATCCTGGAGCAGCATTGCCGCCTAGTAATCGTCATCAAAAGGAAACAGATTCGACGGACTCAGGTCTACATAATTCGACTTTTAGTCAAACTGTTGGAAGTGTATCGACGATACCACAAAGCTGCCAGTGGTGTCATAAACAGTACGCTAGTAAAgcaAAGTTATTACAACATCAACGTAAAAAACACGCGGCGTTATTAAATCCAGCAGATAAAATTCCTCGTCCACGAAATCGTTCTTCATcccaacaaaataattcatcaCTTAACGACAATAATTTTGTCATGTCCGATTATATACAAGGATATGACGTCGATACTGACGTTGATTTTCTAAAACccaaaatacttaaaatatctgacgactcaaattttattgataacgaTATTGATAACGaagatgatggtgatgatgatgacgatgatgatgatggggCTGGAGCTGAAGGGGATAATGACAATCTTGAGCTTGTCGAGCAACAATTTATTCGTATTTGCGATATtcgttga
Protein Sequence: MDPRGPQRAGAPINPTTITSTISDVNSAVDKSLLDTVVDDNWHGVGNTAKNNNRLLFLTVEYVDDYQSRDYSKVFSPYEQVSFYSPRAPSPLSDFEHSKVSPLDPNMSSTARYSPTPVQQLPSLAFPNSVVVLPGPPSPLIIPSDGHARVNINNYISSHNNTIQNVAQSGDSATIDFVNNEAHGESLVTSVNGELILMQGTSTELESTSSSSSSVSADTAAAGPLMLAEIPEAEFALTREFLVMQDDDHLNVVNSLPNQNCEIKEEQIMITDDNIIDNHQTELLNLNNGNGVISQEQVLGKILKNNIECKKLIKNIPASGKITLRKNKKQIRNKTTLECEECISAACLKSGECTCRNVRTIADQPVPSRAVATLPGSYLAINKLLSATAIGEPIGQSNYGVFAKRNIRQRTQFGPIEGILRPYNGEFLKNNGLPLLYETNDGQLLKVDVSDENTSNWMRFVRPALTFDEQNLVICQQSDGIFFLTTRNILSKEELKAGPSSQYALRRNLTVLQPGSLLKDKEIHQDDSNINGWPYLECDEPFKSSEKLSEPLDAHQDKSEATENFESQQNNSKLSSDDNNKSLKVVDGQTVLYSCSQCPKVFPRSYSLKRHMHMHLGSKAPQKYECSTCGENFLHPYNRSRHIKIFHSDETREKENARESSSEYKCKSCNLAFKKLSLLNIHKLIHEQDVNKEHDGSSTSSLSSACPQCGVTFNTWYDLINHVSSKHGRIKLPKVTSTSKVNNNNNNQNQNQVSTPPMYKCTKCYKRFATKVRLQQHFLVHGAEDQKPLPCNVCCKRFMNNSALSCHLKTHRQDKQLFECPMCRKLFNQVLMLKEHIETHRGEDGIFSCPHCPRTFTKYSVIRKHIRAHHCERKHKCQFCSKPFPTIDKLRMHLLRHSDHREFHCANCGKQFKRKDKLKEHMTRMHNAQKIKRDQITTQNSNNNNNNNNDNISNNNNDNDNNSQGKKFVPKVNPTDYNRFIYKCHQCLVGFKRRGMLVNHLAKRHPDVSPDSVPELNLPILRQTRDYYCQYCDKVYKSSSKRKAHIMKNHPGAALPPSNRHQKETDSTDSGLHNSTFSQTVGSVSTIPQSCQWCHKQYASKAKLLQHQRKKHAALLNPADKIPRPRNRSSSQQNNSSLNDNNFVMSDYIQGYDVDTDVDFLKPKILKISDDSNFIDNDIDNEDDGDDDDDDDDGAGAEGDNDNLELVEQQFIRICDIR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00380568;
90% Identity: -
80% Identity: -