Mdem010681.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Microplitis demolitor
Gene Symbol
-
Assembly
GCA_000572035.2
Location
NW:211141-216600[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.029 2 8.4 0.5 1 23 365 387 365 387 0.97
2 18 0.0091 0.65 9.9 0.7 2 23 423 444 422 444 0.97
3 18 0.0011 0.077 12.9 1.0 2 23 538 559 537 559 0.98
4 18 0.0027 0.19 11.6 0.6 2 23 604 625 603 625 0.97
5 18 2.5e-05 0.0018 18.0 0.5 1 23 630 652 630 652 0.96
6 18 0.0019 0.14 12.1 0.4 1 21 658 678 658 682 0.92
7 18 0.00013 0.0093 15.8 1.0 2 23 762 783 761 783 0.95
8 18 0.00015 0.011 15.6 4.8 1 23 839 861 839 861 0.97
9 18 0.0002 0.014 15.2 0.7 1 20 866 885 866 887 0.94
10 18 0.022 1.6 8.8 0.6 2 23 898 919 898 919 0.97
11 18 2e-05 0.0015 18.3 0.6 2 23 957 978 956 978 0.97
12 18 1.9e-05 0.0013 18.4 1.6 1 23 983 1005 983 1005 0.95
13 18 0.0012 0.084 12.7 2.9 1 23 1011 1033 1011 1033 0.98
14 18 5.6e-06 0.0004 20.0 0.4 1 23 1050 1072 1050 1072 0.95
15 18 1.1e-06 7.5e-05 22.3 0.3 1 23 1078 1100 1078 1100 0.99
16 18 0.00024 0.017 14.9 0.2 1 23 1106 1128 1106 1128 0.98
17 18 0.00011 0.0077 16.0 4.1 1 23 1134 1156 1134 1156 0.96
18 18 0.0076 0.54 10.2 0.4 1 20 1162 1181 1162 1183 0.89

Sequence Information

Coding Sequence
ATGGACGCCGTTGATATTGAGGATAATAATCAAGTGTCGCACAACGACGATGACAATGTGGATGGGAACGTTGAAATTTGCCGGGTTTGTCTCCTCAGCAATCACTTGATGAGAGATTTGTTTGGAGAAAATGACGTTGTTTCATTATCTACTAAAGCCATGAGCTTTGCTAATGTTAAGattcatcCAGATGACGGATTGCCAACTCAAGTCTGTTGCGAGTGCGCTGACAAATTAGAATCCGcgtatgaatttaaattacaagtcGAACAAGCTGACAGTTtgttaagagaaaaatatgaCAGCTTGAATATCAAAGaagagttattttttaacgaagTCGAAGTGCGTTTGGAAAACGAAAGGCATGATGATGTCACGGACATGGTTGACGAGCACTACGAAGTAACGGGCAGTGTGTCAGATGATAAGACGTCATTACTGAAAGATCACTTGGCATTATTACAAGTTGAAAAACTTACTCATCACCAAGAACAATATTTAGAAGATGAAGTTATGAAAGATCAAATAATGCAATCGGATGAACAATACATTGAAGACGAGCACACAGATGAGCAAATGATTACTGAAGCTATTGAGTCGTCAGcaaatgataatataaaaccTGAGTCAATAATGCATGACCAAGACGGCATTGCTGTTGAAGAACACAATTACATTGTACAGCACCAGGACTACACGCTGTCTAATGAGCAAGATCatgaattaattaacactGATAACGTTAATGAACACGATGCAAgtgaatatttatcaataattggaGACGAAGAAAGACTAATTAAAGAAACTGAAAGCCATTTAGAGAATGTCattgatgatgaaaaaaataattgttatattaatgacaatgatgaggtcaatgatgatgatgatgatgacaataataaattaaacacaattgatgaaattgaaatgagtaaaaatgaatgtaATAATGCATCGACATGTCATAATGACATTGACCCAACAGACCAAGGGTCTGATGACGAAAACTattttgaaaatcttaatttaagcAGCCGATTATCACAAACTCAATCAGTTAATAAacctgataataaaattttctttatgtgTTACATTTGTGATCAAGAATTTTTGTCGaaagatattttgaaagaGCACATGAACTCGCATGACGAAGTTAAACAGACGTTGTCTATGAAAAAAACGCCAGATAAAGCTAcgcagaaaaatatttctcctATTAAATCACAACCACCTTCGGGTAAAAAACCTAACAAATGTCCTTACTGTGGTAAAGAATATTTGTATgttatatcatttaaaaaacacattaaacaacatcaaaaaaatgacGATGAGTTGAAAGAAAACATGGATTCGTTACTTCAGAATGATAATTCTGcggattcaaataattatgacaACACTGATACGTTTGAAGTGATTGCTGATGATAAACATAATATCGAAGAGTACACTGATAATGGTAATGATAATAGAAGTATTAATGTAGATATTGatcatcaaaatttaagtaaacatGGTAATAATTGTccagatattttttcagataattgtAACGAAGCTTCAGCTCATCAGGATTATCAAGATGATAAACAAAAGTGTAACATTTGCGAGCTGGAATTTGACTCGatggataaattaaaaaatcatcggTCGACTCATGTTATTGAAGGCGTAATAACAGAACAAGATTTAAAAGACGAGCTTGCTAGTATTTGTCAAAGAGAATATGACCaagagaaaataattgatgGTAATTTACAATTGGAAGTTAAAAAGGAATATAATGAACTCAAGTGTCCTACTTGCTTTTTATTGTTTGGTAGTAAAAAATCGCTGGCAAAACATTTAGAGACACATGAAAGTATAAGATACCGTTGTAAAATATGTGGTGATGAATTTACACAGAAAGACGATCTTCGTAAGCACGCTGAACAACACTCGCAAGTTAAAACATTCAAATGTATGCAGTGCAACAAAATATTTGCCAATGAACTGACACTGAGAAATCATTTGATAGCAACAAATCACAAGACAACTGTACACGGTGAAGAATATGATccaaataaaagaattaaaagagTGGCAGCACGTGCAgcgcaaaaaataattgacaaaattAGCACTGAAGACAGCCTTGATGACTCGGAAAgagatgatgacgatgatgattaTGACGAGTTAATTTTGAAGAGTGAGTCGGGAGTTAGTGGAAAAACTGGAGAAAAATCggtgtcaaaaaaattgtttggtaaaagtaaaaatcttGAATGTGAAACTTGTGGCAAGAGATGTATTTCTAAGCAAGCGTTGGCTAAACACATGGATTATCATATGAGAAATATGAAGGCTGAGTCTCCAgagtcgaaaaataaaaaaaataatgaagtaaaAGATATAACTCGTAGTGTTCCTGGATTTTCTGATATcaatgatgatgacgatgatgatgatgatgacaatgATTTTGATGGGGGGTTGGACTGGCCAATGGACAATCACGAGTGTTCGACATGTAAGAAAAGATACAGTACGAAAAAATCATTGTTGCGACATCAGCTTTTACATGAGGAGCCTAATTTTGAGTGCGATATatgtaatgttaaattttatcgcAAAGACAAATTAAAAGCACACTACGATAAATGCTCGGAAAAGAATCCAAATCAAGTGAGGAAGTGTAATATTTGCGGCGATACCTTTGagaataatgatattttacgTGAACACAGATCAAAACACGTTGACGAGGGCATACTTACCGAGGAAGATTTGAAAGATTTGGAGCCTGGCTCTGAGGACAGAAAGGGAGAGAAAATAGCGAGGAAGAGACGCACTGATATTGTTGGATTGGAATGCACTGAATGTAACAAACAATATACGTCACGTAAAGGTCTTCTGAGACATATACAAGTGCATGaaggtaaaaaatatctttgcgATATATGTCCAAAGAAATTTTACCGCCGTGagcatttgaaaattcatgtCGCTAAGCATAATATGATAAAACCACACAAGTGTCCGCGTTGTTCAAAACGTTTTATGAAGGAGGAGCAGCTTTCCGCGCACTTGACTAAACACGAGAGAacgtttaagaaaaataaagaaccTGACAGTACATCCAAGAGATTTCTCTGTGAAATTTGTTCGAAAAGTTTTACTCAATCGACGACACTGGTTGCACATTTGCGAGCTCACAATGGCATAAAACCTTATGTATGTGAAGTTTGTGCAAGACCATTTACAACAAATGCATATTTAAAGATGCACATGAGAACTCACACACAAGAACGACCGTACACATGTCAATTTTGTGCACGTGCTTTCGCGAGAGCTGATACACTCGCAAATCATTTGACTTCACACACCGGCGAGGCCAAATATCACTGCAAGTATTGTCCGAAAAATTTCCGTCGACTGAAGTCACTCAAAGAGCACGTATTTATTCACACTGGACAGCGACCCTATGCCTGTCCTACGTGCGATCGAAGATTTAACAACAACGGAAGTCGCTATGCTCATAGCAAAAGATGCAAGCAGAATATGCTGCAGAATCAAGCCAGACAAAATCAACCACAAACTTCACAACCTCAAATTACTCAGCCTCAAATCACCCAGCCTCAAATCAGTCAACCTCAAATCAGTCAGCCTCAAATCAGTCAACCTCAGATCAATCAGCCTCAAATAAACCAACAGACAATAGCAATAGCATCAGCACCACAAACAGCTACCATCAGACTGGCACATTCTGTTGGCCCGACAATGCAAGTGGTTCAATCGAAAAATGTCAAGACAATAACAATCACAAGACCTGAAACAGTTGGTACTCATCAAATTTTACAACACCAAGAATTACTCATGCCACTTATTTTACCTCTTACTGTTACATTAACTGATTGCGATGACGAAGTTATTTTACCAGAGGGTACCAAGATATTTACCACTACGTAG
Protein Sequence
MDAVDIEDNNQVSHNDDDNVDGNVEICRVCLLSNHLMRDLFGENDVVSLSTKAMSFANVKIHPDDGLPTQVCCECADKLESAYEFKLQVEQADSLLREKYDSLNIKEELFFNEVEVRLENERHDDVTDMVDEHYEVTGSVSDDKTSLLKDHLALLQVEKLTHHQEQYLEDEVMKDQIMQSDEQYIEDEHTDEQMITEAIESSANDNIKPESIMHDQDGIAVEEHNYIVQHQDYTLSNEQDHELINTDNVNEHDASEYLSIIGDEERLIKETESHLENVIDDEKNNCYINDNDEVNDDDDDDNNKLNTIDEIEMSKNECNNASTCHNDIDPTDQGSDDENYFENLNLSSRLSQTQSVNKPDNKIFFMCYICDQEFLSKDILKEHMNSHDEVKQTLSMKKTPDKATQKNISPIKSQPPSGKKPNKCPYCGKEYLYVISFKKHIKQHQKNDDELKENMDSLLQNDNSADSNNYDNTDTFEVIADDKHNIEEYTDNGNDNRSINVDIDHQNLSKHGNNCPDIFSDNCNEASAHQDYQDDKQKCNICELEFDSMDKLKNHRSTHVIEGVITEQDLKDELASICQREYDQEKIIDGNLQLEVKKEYNELKCPTCFLLFGSKKSLAKHLETHESIRYRCKICGDEFTQKDDLRKHAEQHSQVKTFKCMQCNKIFANELTLRNHLIATNHKTTVHGEEYDPNKRIKRVAARAAQKIIDKISTEDSLDDSERDDDDDDYDELILKSESGVSGKTGEKSVSKKLFGKSKNLECETCGKRCISKQALAKHMDYHMRNMKAESPESKNKKNNEVKDITRSVPGFSDINDDDDDDDDDNDFDGGLDWPMDNHECSTCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPNQVRKCNICGDTFENNDILREHRSKHVDEGILTEEDLKDLEPGSEDRKGEKIARKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPHKCPRCSKRFMKEEQLSAHLTKHERTFKKNKEPDSTSKRFLCEICSKSFTQSTTLVAHLRAHNGIKPYVCEVCARPFTTNAYLKMHMRTHTQERPYTCQFCARAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQNMLQNQARQNQPQTSQPQITQPQITQPQISQPQISQPQISQPQINQPQINQQTIAIASAPQTATIRLAHSVGPTMQVVQSKNVKTITITRPETVGTHQILQHQELLMPLILPLTVTLTDCDDEVILPEGTKIFTTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00382050;
90% Identity
iTF_01004518;
80% Identity
-