Mdem007228.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Microplitis demolitor
Gene Symbol
ZNF236
Assembly
GCA_000572035.2
Location
NW:379849-401321[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 0.00011 0.0078 16.0 2.9 2 23 175 196 174 196 0.97
2 28 9.3e-05 0.0066 16.2 0.6 1 23 202 224 202 224 0.98
3 28 1.3e-05 0.00091 18.9 0.3 2 23 230 251 230 251 0.97
4 28 0.00068 0.049 13.5 0.2 3 23 259 279 257 279 0.96
5 28 3.1e-05 0.0022 17.7 1.0 2 23 290 311 289 311 0.97
6 28 1.8e-06 0.00013 21.6 1.4 1 23 332 354 332 354 0.99
7 28 1.3e-05 0.00094 18.9 1.2 1 20 360 379 360 382 0.94
8 28 8.3e-06 0.00059 19.5 1.5 1 23 388 411 388 411 0.97
9 28 0.0076 0.54 10.2 2.1 1 23 420 443 420 443 0.97
10 28 2.5e-07 1.8e-05 24.3 2.5 1 23 538 560 538 560 0.98
11 28 0.0057 0.41 10.6 3.3 1 23 566 588 566 588 0.99
12 28 0.003 0.21 11.5 6.5 1 23 594 616 594 616 0.98
13 28 1.1e-05 0.00081 19.1 3.3 1 23 620 642 620 642 0.98
14 28 0.0025 0.18 11.7 3.4 1 23 696 718 696 718 0.98
15 28 6.1e-06 0.00043 19.9 0.7 1 23 724 746 724 746 0.99
16 28 0.0014 0.099 12.5 5.0 1 23 752 774 752 774 0.96
17 28 0.00036 0.025 14.4 7.4 1 23 780 802 780 802 0.98
18 28 6.6e-05 0.0047 16.7 0.1 2 23 1112 1133 1111 1133 0.95
19 28 0.83 59 3.8 3.9 2 23 1164 1185 1163 1185 0.91
20 28 1.8e-05 0.0013 18.4 2.1 1 23 1191 1213 1191 1213 0.99
21 28 0.0001 0.0075 16.0 0.7 2 23 1222 1243 1221 1243 0.97
22 28 6.3e-08 4.5e-06 26.2 2.1 2 23 1309 1330 1308 1330 0.98
23 28 0.018 1.3 9.0 6.1 1 23 1336 1358 1336 1358 0.97
24 28 6.3e-06 0.00045 19.9 1.9 1 23 1364 1386 1364 1386 0.98
25 28 0.0027 0.2 11.6 5.8 1 23 1392 1414 1392 1414 0.99
26 28 0.00015 0.011 15.5 2.3 2 23 1656 1677 1655 1677 0.97
27 28 3e-06 0.00021 20.9 3.1 1 23 1683 1705 1683 1705 0.98
28 28 1.3e-07 9e-06 25.2 2.5 1 23 1711 1734 1711 1734 0.98

Sequence Information

Coding Sequence
atgctaaCAGAACAATCATCGGATACAATATCTCTATCGATTGATTCATTACCACTTGGTACTCAgggttttcttatttttcatgatgGTCGTACGTTATTAGTGACAGaacaCAATGATGATTTATCGGAATTTTTATCGACGCCAGTGACATTAGTTCAATCAAATGATATCCAGTCTAAGTTACCAAATGGcaattcatcaattaattcatcagtaGTTCAAGTAAATTTGGGGAATTTAATAAACGcaaataatttacaacaaaCGTTAATTCAAAATCAGACAAATGTACCAATTCATGTTGACTTCAATGAAGATGCTGATGCTGAAATCATTCCAAAacagtttgataaaaataatacatttgaGACCAGTGTTagtatgtttaataataatgatagttttATTGAGGAATCGAGAATATATATAccaattttaaacaaaactgTAAAAAGACCGCGTCCTGGAAGACCACGAAAAGGTGCTGTCGCTCCATCAGATtcagctaaaataagtattaaatgtGAAATATGTGgtgaagaatttgaaaaaccaATGCATTATCGCAAACATATGAAACATCATGGTGAAGAAAAATCGCATCGTTGTCCAAAATGTCCAGCGTCTTTTAATATACCCACAAATTTCACGCTTCATATGGCGACGCATAATTTAGGGGAACCAAAATGTCCAGAGTGTGGCCGAAAATTTGCACGAATGGCCAGTCTTAAATCTCATTTAATGTTGCATGAAAAAGAAGAACATTTATTTTGTCAGGAGTGCGAGGATGTATTTCCAACAAAAAGTCAATTAGAAGCACATTTAAAACTTCACAATGAAAAATGGTCAACGGATTACGTAAAAAAGTGCAAACTCTGCAACAAGCAATTTACTCAACCCGCTCTTTATCGTATTCACATAAGAGAACATTATAAAttgcaGACTAAGATGATGAAGCATACAAAGAGAGGACCGACTAAtagagttatatataaatgtaaaatatgtttgaaaatgtttcaaaaaccCAGTCAATTAATGCGACATCTTAGAGTACATACAGGCGAAAAACCTtacacgtGCAATATTTGTAATAGATCGTTTTCACAAAAAGGTTCACTTCAAATTCATAAATGGAAACATATTGGTATTAGACCGTATCATTGTGGTCAATGCGATTCGAAATTTAGTCAAAAAGGTAATTTAAATGCTCATATTAGAAGAGTACATCGTCAACCAGATGGTGAGACAGCTTATCCATGCTTGCGATGTACATgtgcttttaaaaaattagcaagTTTAAGTATGCATATGAAAAAAGTCCATGCTGTTCCTATAGAAaatACAccaatatttgataattcaactccgaatttaaacattaaaaagtCTGGAGAGTCAGAGGACAAAAGTGATATACTACAAGAAGCTTTGAAGATAAGCGGCTTATCGGATAAAGGAAAAACTCCTAATGCTgATAATGTAAATTCTCCGAAAGTTAAAGAAGAAGTACAAACTTGTTATGTAACACTCATGGATAAAACACCTGAAGGTGGTttcagaCGATATGTTACAATAAAACAACGTAGTATTGGTCATATAAAATGGTACTCTTGCTCGTATTGTCATAAAGAATTTAGAAAACCATCAGATCTAATTCGTCATTTACGAGTACACACTCAAGAAAAACCTTACAAGtgttCATACTGTTGTCGTTCATTCGCTTTAAAGTCAACCATGATTGCCCATGAACGGACACACAcaagtacaaaaaattatatttgtggGACGTGCAATAAAAAGTTCACTTGTCATAGCAGTTTAAAAGCTCACAccagAACGCATACAAAACCACACAAGTGTAACTCGTGCGGTAAATCATTTAGTACAATTACCCTATTGAAAAGTCATATGCAAAACCACATGAAAACATTATCAGCCGATGCAGAAGCTTTGATACCACAAATTGTATTAGAAGAACCATTGGTAATAAGTGATGCTGGTGATAAAATAAGTGTTGCTCATGTTAAATCTAAACAACAGAAAAATGGTGATGATAGCAATGATAGTGCTGGTAGACCACACAAATGTTGGGCTTGTCCAGCAGcatttagaaaaataagtcATTTAAAACAACATTATCGTCGTCATACTGGCGAACGTCCATTTAAATGCCCAAAATGTGACGGTAGATTTACATCAAATAGTGTTCTTAAGGCTCACTTACAGACTCATGAAGCAGCTAGGCCTCATAATTGTACTGTTTGTAAtgctaaattttcaacacACAGTAGCATGAAACGTCATTTAGTTACTCACAGTAATGTAAGACCGTTTATGTGTCCTTACTgtcataaaacatttaaaactaCTGTCAATTGTAGAAAACATATGAAGATACATAAAACAGAACTTGCTCAACagCAGTTAGCAAAACAAAAtgtacaagaaaaaattattgaaactcCAATACCAGATAAAGTAACAATACCCACattaacagaaaatttaaatttaccagaAGATATTACAAATACTTTCCAACCAAATATAAGCTCTGATTTTACTCAAGCATTCAATGACCAGTTTACATCTATGGATGTGGACAAAAGTAAATCGTTTTTAACTGATGATAGCCGTACTGAAACActagaaaatttaccgcAAGTTAATACAAATCAGTTGGAGCCGACTCAAACATTACATGCCGATGAAACTGGTACTATTACATTACCTAATTATTCTGGAGATCAAACTCTTACAGCAGAAAGTATTCGTGAAATAGAAGAAACTTTAAATCAacagttatttaatattggTATGAATCTCGGtttgaatacaaatttatcaCGACAGATAAGTGAAACAGATGTACCATTAGAAACTCGTGAGCAACCGGtactaaatataatatacGACAACTCAAAGACCCTTGATTCATCGGataatattaatcaaaatatttttccgccGCACTTTGACACTTTTGACATGAGTCAAATAACTCTGCAGGCAGATACTGAAATGGATATTGGAATAAATTCAGCGAATTCAACAAGTATGGCAAGTATTTTACCAAAATCAGCTCAAGAAGCTCAACGATTGGTTCCAGTTTCTACTTGTAATACCACCATTACAACTACATCAGAGTCAGGTCAATTAAAAGAATCGCGACATCTTGTTGTTAATTCAACTCCATCTTATTCAGATTTATCTAAACCTGTACAATCTTGTCCAAAGTATCCTAAAATAATAGCCAAAGCCGATACGACTAATGaagtagatattttaaatttaaacagtgAATCTAATGATCATTCAGTTCCATTAGTTTGTAATTATTGTGACAAACTATTTGGACAACTGGATGAATTAAAAGCACACATGGATAATCATGTGTCTGGTTTAACAAACATTGATACAACTACTGATGATAGTAGCAatacaagtattaaaaaaattattgaaaatagtaACGGGTCATTGCAATGTCATATGtgttataaaaaagattttgatgTTAATTCATTGaagaaacatttaaaaactcaTCGTGGTGAAAAAGAATTTCAGTGTACAGAGTGTCCgttaaaattttgtaccaaCGGTGGACTAAGTcgtcatttaaaaatgcatgcatgtaaaaaaatagataactGGACATGCTCCGtatgttttgaatcattttcaACAGAAAATCAGTTAACGATTCACAGTAGAACACACGATATTGGTTGGAATTCACAAATAGAACCTGACAGCTCACAACAAGATTCGCTAAAAATTGAGTCGgatttattgacaataaattcCGATTCTGTTGTATCAGTATCggaaaaattactgtttgaTACAGTagttgaacaaaattttattaaaaataaaaataatgattttcaaGAAAAGAAAGAGTATgacaataaatgtaaatattgtcCGAAAACTTTCAGAAAACCAAGTGATTTAACTCGTCATGTAAGAACGCATACTGGGGAACGTCCATATCAATGTGAACATTGTGATAAAAGTTTTGCTGTTAAATGCACTCTAGATTGTCACATTAAAGTTCATACaggcaatgaaaaattttcttgtcacGTTTGCAACAGATTATTTGCAACAAAAGGAAGTTTGAAAGTTCACATGCGTTTACATACTGGTTCAAAACCATTTAAATGttctatttgtaatttacaatTCCGTACTTCGGGTCATCGTAAAGTACACTTACATACTCATATGcgtgataatgataaaaatataagtggcaataatacaattaataataaacgtaaACAAAAGTCaacaaaaattcaagtaatacccgagtttaaaaatgaaattgatgaAGATATGAGTGAAGAATCATTAGTGGATGTTAATCAAcaaaatgaatattcaaatatcgATACAATAACAATTGACGCTACTGGATTGTCAGATCAACTAACATTTAATGCTGATGGtacgatattaaataataattcaatgttATCTATAAATGAAAGTAATCAGCTTGTAgctaatttacattttttaattgccaATGGACTGGTTACAATACAagctgatgaaaatttattaccgcAATTGAGtgttaataatgataatacacATAATtctaatattaatgttaatcaTAATGTTGACAATCAAAATGAACATACATTAGTTGCACCAACTACACTAGAACAAGTATCAAATATTCAAACTAATAGTTTAGTTattacacaaataaataatctttcaTCTAATGTAGAGCGCACTCCGCAATTACAATTGAATGATTGTATGGCACTCGTTGATTTACCATCAACTACTTCAAGTATAGTTAATGAAATTCCATCATCACAACCATCAGCGTCAATTCCAGTCTCAGTATCAGTACCAGTAATTCCACAATCAACAGAATCAATTGATAAAGTTggtaacagtaataataaaacatcaaataataaaaaagaatgtgATATTTGTGGTAAAACATTTATGAAACCATGTCAAGTACAAAGACATAAACGTATTCATACAGGTGAGAAACCATATAAATGTGAATTATGTTGGAAATCATTTGCACAGAGATCGACATTGCAAATGCATATGAAGCATCACACTGGTGATCGTCCCTATTCTTGCCCCCATTGTGATTATTCATTTACACAAAAAGGTAATTTACAAACTCACCTCAAACGTGTACATCAGATGGACGAtactaatgataaaaaaaaattaaaaacaacacaacacataattaataataaaattatacagcaGGATGATAATGGGATCCCTAACTTGGATGATATTTCAATAGTTGAATTACTTAagtaa
Protein Sequence
MLTEQSSDTISLSIDSLPLGTQGFLIFHDGRTLLVTEHNDDLSEFLSTPVTLVQSNDIQSKLPNGNSSINSSVVQVNLGNLINANNLQQTLIQNQTNVPIHVDFNEDADAEIIPKQFDKNNTFETSVSMFNNNDSFIEESRIYIPILNKTVKRPRPGRPRKGAVAPSDSAKISIKCEICGEEFEKPMHYRKHMKHHGEEKSHRCPKCPASFNIPTNFTLHMATHNLGEPKCPECGRKFARMASLKSHLMLHEKEEHLFCQECEDVFPTKSQLEAHLKLHNEKWSTDYVKKCKLCNKQFTQPALYRIHIREHYKLQTKMMKHTKRGPTNRVIYKCKICLKMFQKPSQLMRHLRVHTGEKPYTCNICNRSFSQKGSLQIHKWKHIGIRPYHCGQCDSKFSQKGNLNAHIRRVHRQPDGETAYPCLRCTCAFKKLASLSMHMKKVHAVPIENTPIFDNSTPNLNIKKSGESEDKSDILQEALKISGLSDKGKTPNADNVNSPKVKEEVQTCYVTLMDKTPEGGFRRYVTIKQRSIGHIKWYSCSYCHKEFRKPSDLIRHLRVHTQEKPYKCSYCCRSFALKSTMIAHERTHTSTKNYICGTCNKKFTCHSSLKAHTRTHTKPHKCNSCGKSFSTITLLKSHMQNHMKTLSADAEALIPQIVLEEPLVISDAGDKISVAHVKSKQQKNGDDSNDSAGRPHKCWACPAAFRKISHLKQHYRRHTGERPFKCPKCDGRFTSNSVLKAHLQTHEAARPHNCTVCNAKFSTHSSMKRHLVTHSNVRPFMCPYCHKTFKTTVNCRKHMKIHKTELAQQQLAKQNVQEKIIETPIPDKVTIPTLTENLNLPEDITNTFQPNISSDFTQAFNDQFTSMDVDKSKSFLTDDSRTETLENLPQVNTNQLEPTQTLHADETGTITLPNYSGDQTLTAESIREIEETLNQQLFNIGMNLGLNTNLSRQISETDVPLETREQPVLNIIYDNSKTLDSSDNINQNIFPPHFDTFDMSQITLQADTEMDIGINSANSTSMASILPKSAQEAQRLVPVSTCNTTITTTSESGQLKESRHLVVNSTPSYSDLSKPVQSCPKYPKIIAKADTTNEVDILNLNSESNDHSVPLVCNYCDKLFGQLDELKAHMDNHVSGLTNIDTTTDDSSNTSIKKIIENSNGSLQCHMCYKKDFDVNSLKKHLKTHRGEKEFQCTECPLKFCTNGGLSRHLKMHACKKIDNWTCSVCFESFSTENQLTIHSRTHDIGWNSQIEPDSSQQDSLKIESDLLTINSDSVVSVSEKLLFDTVVEQNFIKNKNNDFQEKKEYDNKCKYCPKTFRKPSDLTRHVRTHTGERPYQCEHCDKSFAVKCTLDCHIKVHTGNEKFSCHVCNRLFATKGSLKVHMRLHTGSKPFKCSICNLQFRTSGHRKVHLHTHMRDNDKNISGNNTINNKRKQKSTKIQVIPEFKNEIDEDMSEESLVDVNQQNEYSNIDTITIDATGLSDQLTFNADGTILNNNSMLSINESNQLVANLHFLIANGLVTIQADENLLPQLSVNNDNTHNSNINVNHNVDNQNEHTLVAPTTLEQVSNIQTNSLVITQINNLSSNVERTPQLQLNDCMALVDLPSTTSSIVNEIPSSQPSASIPVSVSVPVIPQSTESIDKVGNSNNKTSNNKKECDICGKTFMKPCQVQRHKRIHTGEKPYKCELCWKSFAQRSTLQMHMKHHTGDRPYSCPHCDYSFTQKGNLQTHLKRVHQMDDTNDKKKLKTTQHIINNKIIQQDDNGIPNLDDISIVELLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01005455;
90% Identity
iTF_01005455; iTF_01004513; iTF_01006475;
80% Identity
-