Basic Information

Gene Symbol
-
Assembly
GCA_030347285.1
Location
JAQQBR010001836.1:977581-978944[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0093 0.68 10.2 3.5 1 23 46 70 46 70 0.97
2 9 4.5e-07 3.2e-05 23.8 4.5 1 23 76 100 76 100 0.99
3 9 0.001 0.075 13.2 1.8 2 23 108 130 107 130 0.96
4 9 0.00011 0.008 16.3 1.2 2 23 137 158 136 158 0.96
5 9 8.2e-05 0.0059 16.7 2.6 1 23 164 187 164 187 0.97
6 9 0.007 0.51 10.6 0.5 2 23 192 216 191 216 0.94
7 9 1.5e-05 0.0011 19.0 10.0 1 23 220 242 220 242 0.98
8 9 3.6e-07 2.6e-05 24.1 1.2 2 23 248 272 247 272 0.95
9 9 0.00057 0.041 14.0 0.5 1 21 277 297 277 300 0.95

Sequence Information

Coding Sequence
atggGTTATACAACTGATGAAGAACATGAAAAGTTTATCAgtgaaatagatgaaaaagaagCAAACACAACGACAGCATCAGATACACAGACAGAAGAagaatttgtgataaaaaagaaaaaatgcaaAAGTTTGCATAAATGCTCTTATAAAGGTTGCAATAAATCATTTTGGAAACCATCAAGATTCCAGTGGCATTTACGACAGCACACTGGcgaaAGACcttataaatgtgaatttaaagATTGTGATAAGGCTTATACAACTTCGTCACACTTAAAACGACATTCAAGAACACACAATCCTATTCATGATgcaataaagtGTCCTAGTTGTAAATTAACGTTAAAAACTCGAGAGAGCTTTCGAAAACACTATCAACGTGTtcacaataatgaaaatcgtATTTCATGCAAAGAATGTGGTGTAGTATTTCGTAAAAAATGTAAACTTGACGACCATATGGCAATGCACAATGGCATAACGTCATTTAAGTGCACAAAATGTAACAGAATATTCTCGTCAATGTATTTAATGAGAAAACACGAAAAGTCTATACACAATCGAGTGTTAAAATGCacagaattaaattgtaatgaaGAATTCTTTCGCTATATCGACCTAAGAATTCATCGTAAAAATGCTCATCCACAAGaGTTTCACTGTGAACAATGTGGAAAATGTTTTAggtataaaagtaaattaaaacaacacatacatacgcatgaattatcaaatataccaTGTCCTTACGATGAATGCAAAAAAGTTTATTCATCCAAATCGAATTTACAACATCATATAAAAACAAAGCATATGGGCTGCTTATTTTATTGCGACTTGTGTGGTATTGGTGTATCAGaaaaatcatcattaattagGCACATTAAATGTATTCATGAACGTGAAAAACCACCGGTTAAAAAACGTCCTAAAGTCGGTGAAGAGCGTCTTCAACGTAAAGACGCTGGTCTACCGCGCAAAAGTATGATTACAAAATTAACCGGAATCATTTTACCTCATGATatggaaaaacaaattttaaatcgCACAAAAGAGTTAGAATTATCAGATCTAATACCTGTTGActgttaa
Protein Sequence
MGYTTDEEHEKFISEIDEKEANTTTASDTQTEEEFVIKKKKCKSLHKCSYKGCNKSFWKPSRFQWHLRQHTGERPYKCEFKDCDKAYTTSSHLKRHSRTHNPIHDAIKCPSCKLTLKTRESFRKHYQRVHNNENRISCKECGVVFRKKCKLDDHMAMHNGITSFKCTKCNRIFSSMYLMRKHEKSIHNRVLKCTELNCNEEFFRYIDLRIHRKNAHPQEFHCEQCGKCFRYKSKLKQHIHTHELSNIPCPYDECKKVYSSKSNLQHHIKTKHMGCLFYCDLCGIGVSEKSSLIRHIKCIHEREKPPVKKRPKVGEERLQRKDAGLPRKSMITKLTGIILPHDMEKQILNRTKELELSDLIPVDC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01001607; iTF_01000784;
90% Identity
iTF_01001607; iTF_01000784;
80% Identity
-