Basic Information

Insect: Microctonus hyperodae
Gene Symbol: Thap2
Assembly: GCA_030347285.1
Location: JAQQBR010000005.1:5546236-5549436[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5.9e-06 0.00042 20.3 0.3 1 23 370 392 370 392 0.97

2 16 0.33 24 5.3 0.0 1 20 398 417 398 419 0.88

3 16 0.33 24 5.3 1.1 2 23 425 446 424 446 0.94

4 16 4.4e-05 0.0032 17.5 0.8 3 23 455 476 453 476 0.96

5 16 7e-05 0.0051 16.9 0.5 1 23 483 506 483 506 0.96

6 16 3.9e-05 0.0028 17.7 1.0 1 23 512 535 512 535 0.95

7 16 0.00011 0.0077 16.3 0.9 2 23 570 591 569 591 0.93

8 16 6.9e-05 0.005 16.9 2.0 1 23 597 619 597 619 0.98

9 16 0.00012 0.0087 16.2 0.3 1 23 630 653 630 653 0.95

10 16 0.67 48 4.4 1.1 1 23 659 682 659 682 0.93

11 16 0.025 1.8 8.9 3.0 1 23 703 726 703 726 0.92

12 16 0.00064 0.046 13.9 0.2 2 23 733 755 732 755 0.94

13 16 0.0016 0.12 12.6 2.2 2 23 763 784 762 784 0.97

14 16 0.0015 0.11 12.7 3.4 1 23 790 813 790 813 0.96

15 16 0.0026 0.19 12.0 1.5 2 23 820 841 819 841 0.97

16 16 0.33 24 5.3 0.8 1 23 847 869 847 869 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5.9e-06	0.00042	20.3	0.3	1	23	370	392	370	392	0.97
2	16	0.33	24	5.3	0.0	1	20	398	417	398	419	0.88
3	16	0.33	24	5.3	1.1	2	23	425	446	424	446	0.94
4	16	4.4e-05	0.0032	17.5	0.8	3	23	455	476	453	476	0.96
5	16	7e-05	0.0051	16.9	0.5	1	23	483	506	483	506	0.96
6	16	3.9e-05	0.0028	17.7	1.0	1	23	512	535	512	535	0.95
7	16	0.00011	0.0077	16.3	0.9	2	23	570	591	569	591	0.93
8	16	6.9e-05	0.005	16.9	2.0	1	23	597	619	597	619	0.98
9	16	0.00012	0.0087	16.2	0.3	1	23	630	653	630	653	0.95
10	16	0.67	48	4.4	1.1	1	23	659	682	659	682	0.93
11	16	0.025	1.8	8.9	3.0	1	23	703	726	703	726	0.92
12	16	0.00064	0.046	13.9	0.2	2	23	733	755	732	755	0.94
13	16	0.0016	0.12	12.6	2.2	2	23	763	784	762	784	0.97
14	16	0.0015	0.11	12.7	3.4	1	23	790	813	790	813	0.96
15	16	0.0026	0.19	12.0	1.5	2	23	820	841	819	841	0.97
16	16	0.33	24	5.3	0.8	1	23	847	869	847	869	0.91

Sequence Information

Coding Sequence: ATGAGAGATCGATGGATTGAAGTAATGCGTTGTGAAAATTTCGAACCAACGCAATATACTAAAATTTGTTCAAAACATTTCACTCCTGATTCTTATGTGACTAATTCTCGGAGTTCAATAAAGCGTTTAAAAAAAGATGCTGTACCAAGCATTTTTGATTTTCCAAATCACTTGATGACAAGGACAACACCTAGAAAACTTCCGACATCGAAATTGCAACCACAAAACATTGAGAttgaaaatgaagatgaatCAGATGAACACacagtaattaaaaatgataaggCCTTTGCAGAGACGcctgtaaaaaagaaaagaactTCCTATGTTGGTGattttaaaaaacttttttattctacgGACGATGATggatatcaaattataatgaacAATATGCTGACAACGAAACAGGAGCAGATAAGAAAATTACAGCAGTATAATAGACAACTTCTTAAACGAGTATCTAATTTGAAtacttcattaaaaaatttaaaacgtCAACAAATGATTGacaataattcttcattgGAACTTTCTGATACTATTCCCGTTGCGAGAAATGCAAGTAAAACAGATGAATTTGATGATTACACTTTAGATTCGATTGATTTCAGTACGGACTCCGAGAAAAAttcgtttgaaaattttccgctattaaaagaaaaatcaacgaactgtatttatgaagaaaaaaataatatcgaaataaaaaataactttcaagtagaaaatgaaaatgatactCTTGATCAAAGTAAAACACATGATAGTGAACATGAAGATATTAAAAGATATTTAGCTCAATTGATGATTATCAAGCAAAAATGGGAAgagattaaattgaaaaaagatttattacaaaaagaactttataattcatatacagAAGATAATATCGAAAAATTATCCAGAATattaaacgaaaaagaaaataattcagaaaATGTTCCGGATTATCTGAAACAAAAAGATAtcgtaattattcaattaaaagatcaagatataatatcattatatgAAAATCATAATATTGCATCGATGTACAATAAATTACcagatttaattgatgaaaatccATCAATGCATAGTTTAGGTGATGATAATCTTTTTGACTGTGATTATTGTCcacaaatattttccaatcgtGATACACTTGAAGTTCATTTGAAGAGCCACgactacaaaatattttatttttgtgatgatTGCGGTAGTGAATTTGCAAATATTGATGCAAAGCAGGCGCATGAAATCACGtgtataaagaaattaatatgtagatattgtgatataacattaaatacaaaggaaaaaaaacgaCAACATGAGCAAAATCATTGTGATACCATTTTTGGTCAGATTTGTGACATGTGCggtaacaaatttaaatatcaaggCACTTTAAATCAGCATATAAAAACTCAACATACAAGTTggaaaaatgtatttgaatGTCCTGAATGCTCGGAGATATTTGCATTtaaacaacaattaaataatcatttaaaattatttcatacaccATCACTAACTTATTTATGTGAAGAATGTGGTGCTGATTTCAAAAATCTATCATCACTTAGGCATCATCAAATAAGAAATCATCAGTCAACTGATAATGAACGCAAAAGTTCAGTTTGTGACAAGCTCCTTTCATCGTACAAATCGTCCAAGCACAAGCGAATTCATAATAAACCATACACGATACAATGTCCTCATTGTGATAAAATGTTCAAAAATACATCAACTTTAAAGCCACATGTAATATTACATGAAGATcaacaacaatatttttgCGATACTTGCGGTGTAGGCTTCAATCATCATGATGAACTCCGCTTGCAcatgaatattcataaaaaatctgATAGTAGTGCACCTGAAGATTATTCATGTCAAATATGCTCggaaaaatttccaaataattcaatgctaGTGAGTCATCGAAATGAAATACATAGGAACGATAAACATTATACATGCCATATATGTTATAGGTTAATGATGTCAATGCGATCTTTAGAGTGGCATATGTTATACATTCATAATGAAAAGCCAACGGGAATTACACTAGATGATTCGAAAAATTCTGTTAATATGGAAAGACATTCCTGCATTCATTGTGATAAAACATTCAAGACAGCGAAGATTTTAATAACACATATTAAAAACATccacttaaaaaataaaataattcaatgtttaGATTGTGGATTGAATTTCAAGTCGAAAATTCGATTAAGATATCATATGATGGCTGTTCATAATCGATTAAAAGGTACAACAAAATGTTCTCAGTGTTCAAAGCGTTTTCTAAATCAATCACGACTTAAAGTTCACATGATTTCACATTCGAAAGAGCAGCCTTATATGTGTGAGATATGTGGTACCAGATTAAAAACAAAGATTCATTTGCTAAATCATCATCAGAATCAACATGGTGATGACCAACCGCTTCAGTGTCGTTATTGTGAATGCCGATTTAAACAAATGGGTGCTTTAGTTAACCATGAAAGAATTCACATCAATGAACAGCCTTATTCATGCATTATATGTGAACAACGTTTCAAAAGTTTTGACGATAAAAAAAGGCATGAAGAAGGACATGAAAATCGTGATGGTGCAGGATCTCAAAAGATTGTTGCTGACGGAAATGTTGAGAATTCAAAAAATCAAGACGAGCAAGTTCCAAAATCAGAAAATGATCTATTAGAGCAAGAATACCAGGCCATTGATGATCATTTAACTGATCAACACAATGAATATGATAGTCAATATGATGTAATACAGACTATCGAGTTTGACGAACAGAAAATAGATAACGAAAATCAAGATTATATTCAAGAATTAAATCAGGAGCATATACAAGACATTCAACAAGAGATTGACGAAGAGATTGATAACATAGCAGAGCATGAATATATTGACGAAATTGGCTTATATGATGACGAAGAGGAAAATTTGGAGCATCAACAATGGCAGCATGAGAgagaaacagaaataaataatgattatgagcaaaaatataaacatgaatatgAATTACTTCCAGGTGAAGCATTCGAAGTTCCAGAAGTGATTATGAATATGGAAGATGAAACAGTTTATTCAGAAGAAGTAATGACAGATAATATtgagaatgtaaaaataacGACAAATCATACTGTCCAGACTGAATCGTCTAtacatattcaacaataa
Protein Sequence: MRDRWIEVMRCENFEPTQYTKICSKHFTPDSYVTNSRSSIKRLKKDAVPSIFDFPNHLMTRTTPRKLPTSKLQPQNIEIENEDESDEHTVIKNDKAFAETPVKKKRTSYVGDFKKLFYSTDDDGYQIIMNNMLTTKQEQIRKLQQYNRQLLKRVSNLNTSLKNLKRQQMIDNNSSLELSDTIPVARNASKTDEFDDYTLDSIDFSTDSEKNSFENFPLLKEKSTNCIYEEKNNIEIKNNFQVENENDTLDQSKTHDSEHEDIKRYLAQLMIIKQKWEEIKLKKDLLQKELYNSYTEDNIEKLSRILNEKENNSENVPDYLKQKDIVIIQLKDQDIISLYENHNIASMYNKLPDLIDENPSMHSLGDDNLFDCDYCPQIFSNRDTLEVHLKSHDYKIFYFCDDCGSEFANIDAKQAHEITCIKKLICRYCDITLNTKEKKRQHEQNHCDTIFGQICDMCGNKFKYQGTLNQHIKTQHTSWKNVFECPECSEIFAFKQQLNNHLKLFHTPSLTYLCEECGADFKNLSSLRHHQIRNHQSTDNERKSSVCDKLLSSYKSSKHKRIHNKPYTIQCPHCDKMFKNTSTLKPHVILHEDQQQYFCDTCGVGFNHHDELRLHMNIHKKSDSSAPEDYSCQICSEKFPNNSMLVSHRNEIHRNDKHYTCHICYRLMMSMRSLEWHMLYIHNEKPTGITLDDSKNSVNMERHSCIHCDKTFKTAKILITHIKNIHLKNKIIQCLDCGLNFKSKIRLRYHMMAVHNRLKGTTKCSQCSKRFLNQSRLKVHMISHSKEQPYMCEICGTRLKTKIHLLNHHQNQHGDDQPLQCRYCECRFKQMGALVNHERIHINEQPYSCIICEQRFKSFDDKKRHEEGHENRDGAGSQKIVADGNVENSKNQDEQVPKSENDLLEQEYQAIDDHLTDQHNEYDSQYDVIQTIEFDEQKIDNENQDYIQELNQEHIQDIQQEIDEEIDNIAEHEYIDEIGLYDDEEENLEHQQWQHERETEINNDYEQKYKHEYELLPGEAFEVPEVIMNMEDETVYSEEVMTDNIENVKITTNHTVQTESSIHIQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01002145;
90% Identity: iTF_01002145;
80% Identity: iTF_01002145;