Basic Information

Gene Symbol
-
Assembly
GCA_949715475.1
Location
OX454418.1:28033818-28037941[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 3.2 3.3e+02 3.2 0.6 1 23 89 113 89 114 0.87
2 17 0.56 57 5.6 1.5 1 23 163 187 163 188 0.95
3 17 0.00014 0.014 17.0 3.2 1 23 200 223 200 223 0.96
4 17 0.0013 0.13 13.9 1.5 1 23 264 287 264 287 0.98
5 17 0.069 7 8.5 4.6 1 23 334 357 334 357 0.96
6 17 0.15 15 7.4 0.4 2 23 381 403 380 403 0.95
7 17 0.73 74 5.2 1.7 1 23 522 545 522 545 0.95
8 17 0.0014 0.14 13.8 0.9 1 23 568 591 568 591 0.96
9 17 0.039 3.9 9.3 0.4 1 23 607 630 607 630 0.97
10 17 0.0013 0.13 13.9 0.7 2 23 643 664 642 664 0.97
11 17 0.00019 0.019 16.5 3.4 1 23 671 693 671 693 0.96
12 17 2e-07 2e-05 25.9 1.1 1 23 699 721 699 721 0.98
13 17 0.01 1 11.1 0.8 1 23 727 749 727 749 0.96
14 17 3.8e-06 0.00038 21.9 4.3 1 23 755 777 755 777 0.98
15 17 0.0034 0.35 12.6 2.6 1 23 783 805 783 805 0.97
16 17 1.1e-05 0.0011 20.4 1.7 1 23 811 833 811 833 0.95
17 17 5.2e-05 0.0053 18.3 2.2 1 23 839 861 839 861 0.97

Sequence Information

Coding Sequence
ATGGGTATCACCTCCGGCTACCTCAAAAAAACGGTCACTGTAGGCATGTGCGTGACCATTGACGTATATCGCTGTGGATATTCGGCCAAACGAATCGAATCGATTTTGGAACATCCTCGTCGGCTATGGGGATATGAGGATCGCTGTGGCTATAAACCTTCACCCCTAGCACACGTGGGGAGTGCTCACGATAAACAAACAAATTCGAGTGTCAAATGTAAAACCATCAGTAGGCAACAGTCTCAATCGGGCAGCCAACAAAGATTCAATTGCGATGTACCTGGCTGCGAGCGTAGCTATTTAGCTTATAAACAGGTTTTAGTACACATGCGAAAACATCACATGAACTCCGAAAATTCGACTGTAAAGCCAAAGGTTCCGTCGCTCCCGTTACAGGATAATGTAACAAAGTCGAAGGCAAATTCCGCAAGTAAAACCACCACTGGACAATCGCCATCGAGCAATATTGATAACAGCCAAAAAAGATTCAAATGCGATATACCGGGTTGCGATCGTAGTTATTTAGCTTATAAAACTCTTGCAACTCACAAAAGGAAGCATCACAAGGATATCGGAAATGTTGTTGCAGGCCAAAGATTCAATTGTAATATATGTGACAAAAGTTACATACAGAAGCGTAACATGTTGGCGCATCAAAAGCAATGTCACAACCTGAAGACAGAGCAGGCTGAAAGCCCACAACATATTGAAGAGCCGCTCTTCCATCAAGTGATGATTGTTTGTGACGAAATCCTAACCACTCCAACTCATGACGACTCGAAAAAGAAATTCACTTGTGCTATATGCTCGCTCCCTTTTGTTAATTATCGCAGTCTGATAGTACATCGAAGGAAATGTCATAGCAGCGAAACGGCAAAGGATAAGGAAACAGAGGTGGCTAAAAAGATTCAGAAAATAGAAGAATCTGATCCAGAAAAGGCCAAGGGGAGTGATGATGAGCAAGAGACCGTTTCAACCACTGCTAGCCGTGAGAAGAAATTCACTTGCTCAATATGTCATCACCAATACTCGTATTATCGTCGTCTAATGGCGCATCAAAAAGAAGCTCATAACATCGTGACGACAAAGGAAACCGTCATATACTCCAGACCAAATTTGACAGAAATCGGCGACAAGCTTGTTTGCGACTTATGCGATAACCTTTTCAATTCGAGAAAGATGTTTCTGGAACACAGGAGGGAAGTTCATAAAATATTTCTCAAGAACCCTAAAATTTCAAATCTTGAAAATTCGAAAAGTTCAGAAGAAGAATCGGAACCAGAGAACACTTGCAATGTGagcgacaaaagttttgggcatGAGCTCGATATGCAATCGCATCAAAGAGACGATCACAACATAAAAGCAGAAGAAGTTGCTGCAGTAATGCATATGCGTGATGAAAGTTTTGTGCGTGAGCGCGATGTGGAATCGCATCAAAAAAATTATCACAGCACGCAGGCAAAAGAAGTTGCTGCAGAAATGGATGAATCCAGTTCGGAAGAGGCGGCGAATGTCGATGAAAACCAAAAAGCTTCAACTTTTGCTAGCTCCAAACACAAATTCAAATGTGCAATATGTTTGCACTGCTATGTAAATTATCgcggcattgtcgtgcatcaaagagATGTTCATGGTATCGAAACGACGAAAGAGACGATAATAATACAGTCTAGAGATGGCTTGGACGACATTGGCAAATTTGCTTGCGACATATGCCATAACCTTTACCGTACGAACGGTTCACTGCTAAGACACAGAAGGGTAGCTCACAATATACACCTCCCAAACCCATCAGTTAAAAATGTGGCAAGGAGATATGAATGTAATATTTGTGAAGAATTATGTTCCGATGGCAACGCACTCAGACAGCACAAAATAACAGAACATGGATTTCCCGACCTTTTGCCTCCACTTGATCCACTAACGTGCAAATATTGTGAGGAAAAGTGTCAAGATCAGGAGTCATTATTGGCCCATATTGCTACTCACGGTACTATCGGAAATCGTTACTTATGTAAACACTGCAACAAAACGTTTAAAGGTCGACAAACACTTCTCGAGCATATTTCCACTCATACCGGTGAACATCACTTTAAATGTCAATATTGTTCGAAAAGTTTTGCCTCTAGTTCGAACTTGGTCACACACATACGAGCTCATTTGAATATAAGAAAATATTCGTGTGCCTACTGTGATAGGCGCTTTGTTCAgatttcggataaaaactatcACGAACTTTCGCATACGAAAGAGGCACCGCACCAATGCGAGGAGTGTGGTCAACGATTCAAGACCAGCACTAAATTAAGAAATCATTTGCGCAGGCACAATAATATTCGTCCACACGAGTGCCAAGTGTGTCACAAGGCGTTTTTTACAGGGGTAGCATTACGATCCCACCAGACGATGCATACCGGCGAGAGGCCGTTTTCATGCGACACTTGTGGGAAAACGTTTCGACGTAGAAACGCACTGAGAGCGCACAAATATTTGCATTCGGACGAAATGAAGTTTGCTTGCACGATATGTGATAAGCGATTTTTCCAACATGCCGGACTTTATTTGCATATGAAAACGCACAGTGTGGAATCGGTTTTACAATATATGGACGAGTAA
Protein Sequence
MGITSGYLKKTVTVGMCVTIDVYRCGYSAKRIESILEHPRRLWGYEDRCGYKPSPLAHVGSAHDKQTNSSVKCKTISRQQSQSGSQQRFNCDVPGCERSYLAYKQVLVHMRKHHMNSENSTVKPKVPSLPLQDNVTKSKANSASKTTTGQSPSSNIDNSQKRFKCDIPGCDRSYLAYKTLATHKRKHHKDIGNVVAGQRFNCNICDKSYIQKRNMLAHQKQCHNLKTEQAESPQHIEEPLFHQVMIVCDEILTTPTHDDSKKKFTCAICSLPFVNYRSLIVHRRKCHSSETAKDKETEVAKKIQKIEESDPEKAKGSDDEQETVSTTASREKKFTCSICHHQYSYYRRLMAHQKEAHNIVTTKETVIYSRPNLTEIGDKLVCDLCDNLFNSRKMFLEHRREVHKIFLKNPKISNLENSKSSEEESEPENTCNVSDKSFGHELDMQSHQRDDHNIKAEEVAAVMHMRDESFVRERDVESHQKNYHSTQAKEVAAEMDESSSEEAANVDENQKASTFASSKHKFKCAICLHCYVNYRGIVVHQRDVHGIETTKETIIIQSRDGLDDIGKFACDICHNLYRTNGSLLRHRRVAHNIHLPNPSVKNVARRYECNICEELCSDGNALRQHKITEHGFPDLLPPLDPLTCKYCEEKCQDQESLLAHIATHGTIGNRYLCKHCNKTFKGRQTLLEHISTHTGEHHFKCQYCSKSFASSSNLVTHIRAHLNIRKYSCAYCDRRFVQISDKNYHELSHTKEAPHQCEECGQRFKTSTKLRNHLRRHNNIRPHECQVCHKAFFTGVALRSHQTMHTGERPFSCDTCGKTFRRRNALRAHKYLHSDEMKFACTICDKRFFQHAGLYLHMKTHSVESVLQYMDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-