Basic Information

Insect: Micraspis discolor
Gene Symbol: topi
Assembly: GCA_030674115.1
Location: JARTUT010000873.1:4014404-4017899[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0021 0.41 12.6 2.1 2 21 125 144 124 145 0.94

2 14 0.0001 0.02 16.7 2.6 1 20 170 189 170 192 0.94

3 14 0.0086 1.7 10.6 2.0 3 23 200 220 199 220 0.95

4 14 0.0038 0.77 11.7 0.5 2 21 239 258 238 259 0.92

5 14 6.7e-05 0.014 17.2 1.0 2 23 317 338 316 338 0.97

6 14 4.7 9.5e+02 2.0 0.1 1 13 344 356 344 365 0.82

7 14 0.001 0.21 13.5 2.7 2 22 381 401 380 404 0.89

8 14 0.13 27 6.9 0.0 1 23 520 543 520 543 0.92

9 14 0.12 24 7.0 0.9 1 23 547 569 547 569 0.91

10 14 6.9e-07 0.00014 23.5 2.4 1 23 575 597 575 597 0.98

11 14 0.019 3.8 9.5 0.2 1 23 603 628 603 628 0.96

12 14 0.32 64 5.7 2.5 1 23 634 656 634 656 0.85

13 14 4.6e-05 0.0092 17.8 1.6 3 23 664 684 662 684 0.97

14 14 6.1e-07 0.00012 23.7 1.0 1 23 690 713 690 713 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0021	0.41	12.6	2.1	2	21	125	144	124	145	0.94
2	14	0.0001	0.02	16.7	2.6	1	20	170	189	170	192	0.94
3	14	0.0086	1.7	10.6	2.0	3	23	200	220	199	220	0.95
4	14	0.0038	0.77	11.7	0.5	2	21	239	258	238	259	0.92
5	14	6.7e-05	0.014	17.2	1.0	2	23	317	338	316	338	0.97
6	14	4.7	9.5e+02	2.0	0.1	1	13	344	356	344	365	0.82
7	14	0.001	0.21	13.5	2.7	2	22	381	401	380	404	0.89
8	14	0.13	27	6.9	0.0	1	23	520	543	520	543	0.92
9	14	0.12	24	7.0	0.9	1	23	547	569	547	569	0.91
10	14	6.9e-07	0.00014	23.5	2.4	1	23	575	597	575	597	0.98
11	14	0.019	3.8	9.5	0.2	1	23	603	628	603	628	0.96
12	14	0.32	64	5.7	2.5	1	23	634	656	634	656	0.85
13	14	4.6e-05	0.0092	17.8	1.6	3	23	664	684	662	684	0.97
14	14	6.1e-07	0.00012	23.7	1.0	1	23	690	713	690	713	0.98

Sequence Information

Coding Sequence: ATGAGAAACTCGGACAATCTTATTTTCAAAGTATATAAGATAAACCAGAATGGAATTATTTCTGCTGTGGAATATGAGCAGGATTTTTATACCCGCGAAGTTCTATCAAAAAGACACATTTCAAGTCAAGAAGCAGTTCCAAATTTACTTTTCGACCAGGAAAAATTAAAACTTAGCTTCAGTAATTTTCAATGCGACGATGAGGATAGCCCTCTTGTAAGTTTTGTGAAAATAGAAAATGTTAGTGAGGTAAGTTTAATACAAGCTGGAGGATATACATGCCCCAAGAACTTCATACCACGAGGTAAGAGAAATTCTTCACCATGTTATTTACACCAAGTGAGAATATCTTTGAATATTCCCACAATGATAAGATGCCAAAATTGTGAGACCAACTTTCCTACTAAGTATCAATATCAAAGACATCAGTGCGAGTTTAATGCAGAAAAAGTAGTTTTGAAAGCGAATGCTGACttgaaagatataaataagggtTTGAGAATCAAGTACGACTGTGATAGATGTGGAAAACAATTTGTTAGCAAAAATAATTTAGAGAGACATCGGATTTGTCATGAAAACTCCAAAGAAAACATCTGTGAGCATTGTAATAaacaatttgttagtgaaaataGATTGAGAATTCACAAAGAAAATCATTGCAAGAAAGTaggagatatttcaaaattttaccgCAGTGATGTTGCAGTTTGGAAATGCAAGAAATGCCATGAAGTATTTTCTTCATTGAATTCTGCAAATACTCATATCGAATCTTGTACAGaggaaatattcaaattgaatCCGAATATATTTAAAAAGAATGATGTTGATATTCAGACACAAGAAGCTTCAGGTGTTGCCTCTGCATCGATTATAAATGATGATCCAAATATAAAAGTATTAGATGAAACCCTAATAGAAAAAATTCTGACCGAGATTCTACTGCAATGTGAATTTTGCAATAGGACCTATGCAGATAAGAATTTACTTTTACTACATCAGAGAAAGCATTCAACTACAAAGAACTACGAATGTGTCAACTGCAATAGCAGCTTTGAGTCTTATGCAGTAGCTGCACAACATTGGTTGAAAATATGCTCAGAAACCTCTAATATGTTCTATCTTCCTAAACTTACTTATTGTGAATATTGCGATAGAACATTCAAATCTCATGAGTTGTTATATGCACATAAGATCAAAAAGAAACATTATACAGTGAAGATGCACATAAACAATACACATTCAAACAGAGAAAAACAAATAGACAGCAGTGAGGCTATTAACAAACTGATTGAAGATGTTTTGATAACATTAGATAGACCTGTTGGAAAAATTTGCCAACTCGCTAAGCTCAACTACAGTGACTCAAATAAGGAGAACGAAGTAGAATCCAATAACAGTCAAAAAGATATGAGTAGTGATGCTCCAGAAGAATCAATTCAGAACGAACTTACAGATAAAcctgaaaaaaagaaaagagGACGTAAGCGAAAATGTCTCAAACTAGGTGTGAGGAACAAAAAATTGCATAATCTGATTAATGAAGGCTATATGTATCAGTGTGAACGATGCCCTCTTGTGTGGGACAATGTATCTGATTTAGAAAAACATAGAGATGAAGAGCATGCGGCAAGTTTTAGTTGCGAAGATTGTGGGCAGATTCTACATAGTGCAAAAGCTTTGCTCATCCATTGCCGAGCTCACAAATGCTTGAAACCCTATGTTTGCGATACATGCGGTAGGAGCTACTCTCAAACCTCTCATTTATGGCAGCATATGAGATTTCACCAAGGAATAAAACCCTTCGCGTGCCCCCATGAAGGATGTGAAGCGAGATATACAATCCGTCCAGATTTAAAAGATCACATCAGAAAAGTTCACACCAGAGAAAGACCATTCAAATGTGCAGTCTGCAATAAATGCTTCTTAACAGGTTCTGTGTATTACCAACATCGTTTAATCCATACCAATGACAGGAGATATGGATgtgatGTCTGCCATAAGAGATTTTTCAGGGCTGATGCTTTGAACAATCATAAAAGAATTCACACTGATGAACGTCCATACCCCTGCACTGTATGCGGTAGAGAGTTCAGGCAAAAAGGAGATCGTAATAAACATATGCGAACCCAGCATCCAGATGCAGTTATCCAGTGA
Protein Sequence: MRNSDNLIFKVYKINQNGIISAVEYEQDFYTREVLSKRHISSQEAVPNLLFDQEKLKLSFSNFQCDDEDSPLVSFVKIENVSEVSLIQAGGYTCPKNFIPRGKRNSSPCYLHQVRISLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKANADLKDINKGLRIKYDCDRCGKQFVSKNNLERHRICHENSKENICEHCNKQFVSENRLRIHKENHCKKVGDISKFYRSDVAVWKCKKCHEVFSSLNSANTHIESCTEEIFKLNPNIFKKNDVDIQTQEASGVASASIINDDPNIKVLDETLIEKILTEILLQCEFCNRTYADKNLLLLHQRKHSTTKNYECVNCNSSFESYAVAAQHWLKICSETSNMFYLPKLTYCEYCDRTFKSHELLYAHKIKKKHYTVKMHINNTHSNREKQIDSSEAINKLIEDVLITLDRPVGKICQLAKLNYSDSNKENEVESNNSQKDMSSDAPEESIQNELTDKPEKKKRGRKRKCLKLGVRNKKLHNLINEGYMYQCERCPLVWDNVSDLEKHRDEEHAASFSCEDCGQILHSAKALLIHCRAHKCLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCDVCHKRFFRADALNNHKRIHTDERPYPCTVCGREFRQKGDRNKHMRTQHPDAVIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00349527;
90% Identity: -
80% Identity: -