Basic Information

Gene Symbol
-
Assembly
GCA_030674115.1
Location
JARTUT010002178.1:3146533-3148746[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.012 2.4 10.2 0.2 1 20 6 26 6 28 0.92
2 15 4.1 8.2e+02 2.2 0.0 3 21 36 54 34 55 0.89
3 15 0.69 1.4e+02 4.6 0.9 1 23 98 118 98 118 0.79
4 15 0.085 17 7.5 3.4 1 20 297 316 297 318 0.94
5 15 0.00016 0.032 16.1 1.3 3 23 325 346 323 346 0.96
6 15 0.0029 0.58 12.1 2.2 1 23 358 380 358 380 0.97
7 15 0.011 2.2 10.3 0.3 1 23 410 431 410 431 0.87
8 15 2.9e-05 0.0059 18.4 0.3 1 23 436 458 436 458 0.96
9 15 0.001 0.2 13.5 2.0 2 20 467 485 466 487 0.93
10 15 2.6e-05 0.0053 18.5 3.4 1 23 494 516 494 516 0.98
11 15 2.6e-07 5.3e-05 24.8 3.4 1 23 522 544 522 544 0.99
12 15 4e-05 0.0081 17.9 5.5 1 23 550 572 550 572 0.98
13 15 2.8e-06 0.00056 21.6 0.1 1 23 578 600 578 600 0.98
14 15 0.0027 0.54 12.2 0.5 1 23 604 626 604 626 0.98
15 15 0.00031 0.063 15.1 0.3 1 23 634 656 634 657 0.95

Sequence Information

Coding Sequence
ATGGATAGGATACTTTTTAAATGCCCTCTATGCTGTGAGGAGTCTTTTGATTCGCCAGAAAGTCTCAACAATCATATATTGGATATATTAAATAGACCATTAGACTGTCCCCTGTGTGAAGAAACTGTACCAAGTTTAGATGTTTATTTGCAACATCTAAAAGACTGTGAAATTCCCGTCTCTACGGATTCCGAAGATTATCCTTCATTTGATTCTTCCAACGAGGAAAATGTAGAGGCTGAAGGAGATGATGATATTAAGGAAAACAATAAAGCTTTAGATGGAAACGGGTACTACTGTGAGATTTGCGATATCCAATTCCAAGACATGAAAAGTCATCTGAGAGAATATCATATGGGAGAACAAATCATTGTTGAGAGTGAACAACTGGACGAATTCTTAGAGGAATCTAATTCAGAGAACGAAGGAGATGAACCTATGAGTGTTGTTTATATTGAGCAAGATGAATCTGACGAAGAGGAGGAATCTTCAGAGAAGAAACTGcttaaaagtgaaaacaaaCCTGCTGAAAAAGGCAAGGATGTTAATTCAGTTGTTGTAAAAAAAGAGGTTTTAGGGAATCCACCTGCTTCAGACAAAAAAGCTGTTTTGAATTCAACTGCTACAGAATGTAAGGTTGTAAGGAAGCCGTATGCTATAAGAAGCAATCCTGTTCAGGATCCACCTGTTAAGGAGAGCAAGGTTGCTGAGAATCCACCTCCTTTAGAAAACAAAGCTGTTCAGAATCCACCGGCAGTAGAAAGTAAGGGGATTGTCGAAAACAAGGCTGTGCCGAAACAGAACTTGGTTAAGGAACAACCAGCCTTAGAAATAATTTCCTTTGGTAAAGCTGCTGATGGTACCGATGAGGAACTTTCACTTACAGCGTATCGTTGCAAAAATTGTAATGTCAGATTTATCCATCTGCGATTATACAAGGTACATGAATGTAATTCCCAAAAAGATACGATTTGTGATATATGCACGATATTTTTCTCAAGTAAATCATTATTATCGCAACATAGAAAAAAATACCACTCTAAAGAATATCCAGAAGTCGTTAAAAAGAAACACCCTTGTGATATCTGTAAGATTGAATTCACATCGAAAAAGACAATGTTGCTTCATAAAAAAATGCACGCTCCGAAGAAAAACGATCAAGCAATCGACGAACCTGTGAGTTATAACAGCAGCGGAGAGTTAATAACTGATGAAGAAGTGGAAAAGTTTGTTTGTGCAGTTTGCGGAAAggaattcaacaaaaaatacgAAGAGGTCCATATTAGATCTCACTTGGAAGACGCCTACGATTGCTCATTGTGTAACAAAGGATTTCCAACGAAGAACGATTTAACGTTGCATCTTCAAGCACATGCAAacgattcaaaaaaaaaagtttcttgTAACCATTGTAAAAAAACATTCCAGCATAAAGAAGACCTAGATAGTCACATTACCAACGAGTGCCAAAACAGAAAATTCAAATGTAATTATTGCGGGAAACGTTTTACGAAAGCTCACGAGCAAGTTAAGCACGAACGTATTCATACCGGACAGAAACCTTACGAGTGCAAAGTTTGCGGGAAAAAATTCCGAGTGAGTTATTGCCTGACCATTCATATGAGAACTCACTCGGGGATCAGACCGTACTCGTGTGAAACGTGTGGTAAACGGTTCAAATCTCACAGTGCTTTCCGTCACCACACCCTTATACATTCTGACGATCGTTCCTATCCGTGCCCGTATTGTGATAAAGCGTTCAAAACAGCTGTTCAGCTTGCCGGTCACAAAAATTCTCACACGAAACCCTTCTCGTGTTATATTTGCAACAGGCCTTTCGCTTCCATGTACGCTGTAAAAATGCACGCCAAGAAACATGAAAGTCAAGAGGAACTATTGTATAAATGCGAGCTGTGCGGAGCTGAATATTCGAGGAATATAGCGTTGAGAGATCATTATATAGCACATCACGATTATAAGGTGGAGGAAATAgaaaactttgaaaaaaaaatgcctAGTTGGCAAGTTCCCAAGGCCACTCGTAGAACAAGGGAGGAATTGTTAGAGGAAGGTGAGATACCTAAGAAAGCTCGCATGAAATACACATCGTGA
Protein Sequence
MDRILFKCPLCCEESFDSPESLNNHILDILNRPLDCPLCEETVPSLDVYLQHLKDCEIPVSTDSEDYPSFDSSNEENVEAEGDDDIKENNKALDGNGYYCEICDIQFQDMKSHLREYHMGEQIIVESEQLDEFLEESNSENEGDEPMSVVYIEQDESDEEEESSEKKLLKSENKPAEKGKDVNSVVVKKEVLGNPPASDKKAVLNSTATECKVVRKPYAIRSNPVQDPPVKESKVAENPPPLENKAVQNPPAVESKGIVENKAVPKQNLVKEQPALEIISFGKAADGTDEELSLTAYRCKNCNVRFIHLRLYKVHECNSQKDTICDICTIFFSSKSLLSQHRKKYHSKEYPEVVKKKHPCDICKIEFTSKKTMLLHKKMHAPKKNDQAIDEPVSYNSSGELITDEEVEKFVCAVCGKEFNKKYEEVHIRSHLEDAYDCSLCNKGFPTKNDLTLHLQAHANDSKKKVSCNHCKKTFQHKEDLDSHITNECQNRKFKCNYCGKRFTKAHEQVKHERIHTGQKPYECKVCGKKFRVSYCLTIHMRTHSGIRPYSCETCGKRFKSHSAFRHHTLIHSDDRSYPCPYCDKAFKTAVQLAGHKNSHTKPFSCYICNRPFASMYAVKMHAKKHESQEELLYKCELCGAEYSRNIALRDHYIAHHDYKVEEIENFEKKMPSWQVPKATRRTREELLEEGEIPKKARMKYTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-