Marg018197.1
Basic Information
- Insect
- Metopia argyrocephala
- Gene Symbol
- -
- Assembly
- GCA_963576795.1
- Location
- OY756209.1:100320059-100333803[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0014 0.17 13.5 0.0 1 23 149 172 149 172 0.95 2 12 0.0054 0.66 11.7 2.7 2 23 221 243 217 243 0.88 3 12 0.0015 0.19 13.4 0.5 1 23 364 387 364 387 0.93 4 12 0.96 1.2e+02 4.6 2.2 2 23 437 459 436 460 0.95 5 12 0.12 15 7.4 0.1 1 21 528 548 528 551 0.88 6 12 0.0002 0.025 16.1 1.8 2 23 602 624 602 624 0.97 7 12 0.0014 0.17 13.5 0.4 1 23 734 757 734 757 0.95 8 12 7.2e-05 0.0088 17.5 0.1 1 23 806 829 806 829 0.95 9 12 0.00098 0.12 14.0 0.9 2 23 879 901 878 901 0.95 10 12 0.07 8.6 8.1 0.9 1 22 980 1001 980 1003 0.90 11 12 0.37 46 5.8 1.0 1 20 1055 1074 1055 1076 0.94 12 12 0.052 6.4 8.5 0.3 2 23 1162 1184 1161 1184 0.95
Sequence Information
- Coding Sequence
- ATGGAAAACTTGGAACCTTGGAATATGTTTACCAACGATTCCGTGCCTGACGAAGAGAATGACAATGATGGTGAAGGTGTTGAATATGATGAGGGTGAAGTTGGTAGTGATGATGTTCCTCTCTCTGCTGTAACATCATCATCAGCACAACATACGCAGGTTAAAGAAGAGCCTCAAGATGCCGATGAAGAAATATATGATAACGATGCTGCCtataatcaatttaatttttcatctgcTAAAATCTCAAATGACAGACGTCGCGTAGATAATGCCGACGAGGATGATACTGTTTTTGATTTTGGATTAGAATCATCAAACTCGCAGAATCgaagtttaaataaatcttCCACACAGTCATCGGCAACAGAGAAGGAAAGTAGCAAATTAACAAAAGATGGCAAATATTATCATTCAATGGTTAAATATGAAGATGCAATCATTTATATATGTCCAGCCTGCGGCGAAGAATTCAATTCACAAGAAATGtggaaaaatcatttaaatcttATACATCTCTATAACACACGCCGCGGACTAAATTTTATACAGCTTGATAAACTTTATCATGAATGCATGGAATGCCATAGACGCATTGCTATGCATAGCATGGAGAACTTATTAAAGCACAAATTTACTCACTTACCATATAGATGCAGCAAGTGTTTGGTATGCAAACGAGAATATAAATATCGACAGGATCTTATGGTGCACTTAAGAATAACTCATAAAAACGATTTGATAGCACTAataaaaagagaacaaaaaaatcaaaaaccgcaaactatACGTTCTTTACTGAGCAAATCAGATGGTAGTGCCCCTCAAAGTAGTAGATCAAATTCGTCGAATTTTCCTAATAATAATGCCAATAATATTAaggttaaaaatgaattactcAATGAAGATGAGGATGATACCTTGGGTGAAGATAGTTTGCCGCCATCAGCAAAAAGACAACCTAGAGATTTACCGGTCTTTCTTGAGGACGGATCTACAAATGGCTCATCTGGCGATCAACAAATGACAAGTCGTAATAAGCCATCGGCTTTGGATGAAATTGATGATTCACTAGAGGAGTACATTCTCTTTACATGTCCTCAATGTGGTACAGAATGTGAGACACAAGCTCAATGGCAACAACATATTGAGTTTGTACATGAGTTTGGCACAAAACGGGGACTAAACTTTAGAGAATTGCTGAATCAAGCTGCTCAGTGCATGAGTTGCAATGTGATTTTGCAAAATTCATCAATAAGAAACCTTCAAATACACAAATTTAGCCATCTGCCCCATAAAGAATGGATGTCTTGTAAACTTTGCTTTAATTCGTTTAAAGCCAATCGGgatattattaaacatttagCTACTAAACATCACTTGGTGTCGGAAAATAAGGCTACAAAATCCGCACCTGACATTATAAGTAATGAAGAAGATAGTCAAGAAGCATTTGGATCAGGTTTTGGGGGAGCAGATGATTATGATGATGGATTTGGAGCATCAGATGGTAAACTTTTATCTAATGATTTTCTTGCATCAAAATTAAATGATCGTGATGCTTTTGAACAACATATGGCCTACATTTGCCCAGCATGTGGTAAAGaatataatgataaaaaaatatggcGTAAGCATATTGTTGATATTCATAAATTAGGTGAGTTGGAAAATCTTAATTTCGAATTTATCACCGATCGACAATTGAAATGTAGAGAATGTGATAAGATCATAACGAATGCCTATGGTATACAAAATGCTCAGCAGCATCATATGACTCACATGCAGTATAAATCTTTTGCCAAGTGTCGTATATGTCGTAAAACATATACGGATCGTAAGGGCTTAATGAAACACTTGAGGAATGCTCATAAAGTGGGATCGCGGAGCTTTGCGCATAGGGAATCCGAACAGACTTTAGGCTATGGAGGTGGTAATAGCACTGCTGGTAGTCTATCCAATTTTAAGCCATTTGTTAAAAAACCATATAGGATAGCACACTACCCACCTAAAGAAATTGTTAAACTATCAAATTATACATTCGAAATTGTACACTTAATTGAAGATGACGACGACGATAATGTTGCTAGCACTGGTTCAGGAGGTTACGATTTCGCCAAAGGAGATGCTCATTTATATAGGAATGATTCACCAAATGATGTCACTCATAAAAAGAGCAATATTGAACAAATGAGTAGACATAGATGTGTTGACTGCGGTTCAATATTTCCCACAGCTCAATCCCTAAAAAATCATGTTAAAGAAGAGCACGATTTTGACGATTATCAAAATTCGCCATCTCAAACTCAAGTACAAAATGAAGACCAATCAAATGATACTGATGATTTATTAGTACCCAGCCGAGATGCAGACATTCAGAACGAGGAACGCACGACAATGgactgtaattttatttacttatgccCTCAATGTGGCGTAGAATTTCGCTCACAAAATGAATGGCGTCGTCACATCAATGTGGTGCATAATTTTGATAAACGTGAATACCTTGGTTTTAGACCCTTGGACAAGTTTCGCTACCAATGTAAATTGTGTAAAGATACATTGACGAGTTCAAAACTGAAAGGTTTACAGGATCATAAATTTAGGCATTGTCCTTACAAACTTTATTTAAAGTGCGTTCTCTGCGGACAATCATATAATCATAAGCCCAATATGATAGCACATTTAAGGCAACGGCATAATATAATTGATATTATCGATGGAGGAGTCAGTATTTCCACAGAAACTTCACAACAAAGACATTTGTCTAGCTCGATTTCGACCACAAACACTAACAAAGAGTTTAACGATGCACCTTCCAGACCAATACGAAATTCCGATTCTTCCGTAAACAACGCTAGTCGTCCACCAGGCTTAAAGACAGTCGAAGATGTAATATCTTTTCACAATGCAGTCGATCATGAAACTATAAGATATTATTGTCCTTCTTGTAATGAAAATTTTGATTCTCATGTTTTTTGGCGTAAACATATTGTAGACGAGCATAACCTCAATAGTAGGGAAGGCTTAAATTTCCGTCAATTAGACGAACACCATTACATTTGCCTGCAGTGCTATAAACGCGTTACAGTCACACATACTAAAGGTGCAATTGGACAATTGCAATCACATAAATTTAGGCACTTACCGTACAAATCATTTAAATGTACAGCCTGCCAGGGAGAATTTGTACGCaaacaaatgtttttcaaaCATTTGGATAAATCCACCAATAAATGTTCGGGTATAAATCCGGAAACTGGTTTAACGGATAACCTTGATAATAGCACTGTTTTAAATGATGATGATATTGACTTGAGCGCTACATTAGCACTAGGTGAGAAATTTAACACAGAACCTAATAGTAGTGGAACTACATCTTCATCAACAAAATTCTCGTGGCCTACACGCTCTTCATTGCCAGCTCCATCTAGTGGTACAAATGAAACAAACGGAGAAAATGTTGGTTGCTTTACTTTAAATTGTCCTCAATGTGGCGCTGATTTTGAATCAACACGGTGTTGGCGTGAACACATTAATATAGAACATAACCTTAATAACCGAACCGTATTGAATTTTAAGAAGATTGGGCCCAAACTTCATATTTGTTTGGAATGTAACGAACATGTCAATGGCCGAAAATTAAGAGATTTACAAGTGCACAAATTTAAGCACTTGCCATACGGAGCTTATTTACATTGTCGTTTCTGCTCTATGAAATATTTCCATATTAGCAACATGCAagagcatttaaaaaataaacatcaaaatatgttacaaaaaatgaaaaatgatgtCGATGATTATGTAACACTTGATGAAGATGAGGAATGCATTACCGATACTAACACCGACGCAGATCCTGATGAAAGTATTACTGGTGCAGATGATGACATTGTTGATATGGACTTATTAGAAGCAGAGGCCGAAATTGAAGAGGTTGATCCCGATAATGTTGAATCTGATGAACAATATCTTTTAGgttaa
- Protein Sequence
- MENLEPWNMFTNDSVPDEENDNDGEGVEYDEGEVGSDDVPLSAVTSSSAQHTQVKEEPQDADEEIYDNDAAYNQFNFSSAKISNDRRRVDNADEDDTVFDFGLESSNSQNRSLNKSSTQSSATEKESSKLTKDGKYYHSMVKYEDAIIYICPACGEEFNSQEMWKNHLNLIHLYNTRRGLNFIQLDKLYHECMECHRRIAMHSMENLLKHKFTHLPYRCSKCLVCKREYKYRQDLMVHLRITHKNDLIALIKREQKNQKPQTIRSLLSKSDGSAPQSSRSNSSNFPNNNANNIKVKNELLNEDEDDTLGEDSLPPSAKRQPRDLPVFLEDGSTNGSSGDQQMTSRNKPSALDEIDDSLEEYILFTCPQCGTECETQAQWQQHIEFVHEFGTKRGLNFRELLNQAAQCMSCNVILQNSSIRNLQIHKFSHLPHKEWMSCKLCFNSFKANRDIIKHLATKHHLVSENKATKSAPDIISNEEDSQEAFGSGFGGADDYDDGFGASDGKLLSNDFLASKLNDRDAFEQHMAYICPACGKEYNDKKIWRKHIVDIHKLGELENLNFEFITDRQLKCRECDKIITNAYGIQNAQQHHMTHMQYKSFAKCRICRKTYTDRKGLMKHLRNAHKVGSRSFAHRESEQTLGYGGGNSTAGSLSNFKPFVKKPYRIAHYPPKEIVKLSNYTFEIVHLIEDDDDDNVASTGSGGYDFAKGDAHLYRNDSPNDVTHKKSNIEQMSRHRCVDCGSIFPTAQSLKNHVKEEHDFDDYQNSPSQTQVQNEDQSNDTDDLLVPSRDADIQNEERTTMDCNFIYLCPQCGVEFRSQNEWRRHINVVHNFDKREYLGFRPLDKFRYQCKLCKDTLTSSKLKGLQDHKFRHCPYKLYLKCVLCGQSYNHKPNMIAHLRQRHNIIDIIDGGVSISTETSQQRHLSSSISTTNTNKEFNDAPSRPIRNSDSSVNNASRPPGLKTVEDVISFHNAVDHETIRYYCPSCNENFDSHVFWRKHIVDEHNLNSREGLNFRQLDEHHYICLQCYKRVTVTHTKGAIGQLQSHKFRHLPYKSFKCTACQGEFVRKQMFFKHLDKSTNKCSGINPETGLTDNLDNSTVLNDDDIDLSATLALGEKFNTEPNSSGTTSSSTKFSWPTRSSLPAPSSGTNETNGENVGCFTLNCPQCGADFESTRCWREHINIEHNLNNRTVLNFKKIGPKLHICLECNEHVNGRKLRDLQVHKFKHLPYGAYLHCRFCSMKYFHISNMQEHLKNKHQNMLQKMKNDVDDYVTLDEDEECITDTNTDADPDESITGADDDIVDMDLLEAEAEIEEVDPDNVESDEQYLLG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01315911;
- 90% Identity
- -
- 80% Identity
- -