Basic Information

Gene Symbol
-
Assembly
GCA_963576795.1
Location
OY756208.1:192519569-192524382[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.31 38 6.1 0.8 2 19 370 387 369 390 0.92
2 17 0.0057 0.7 11.6 1.8 2 19 436 453 435 455 0.95
3 17 0.62 76 5.2 0.3 3 23 498 519 497 519 0.94
4 17 0.0046 0.56 11.9 0.3 3 23 527 547 525 547 0.96
5 17 0.00014 0.018 16.6 0.2 1 23 554 577 554 577 0.96
6 17 1.7e-05 0.002 19.5 1.7 2 23 585 606 584 606 0.96
7 17 0.78 96 4.8 0.0 1 20 615 634 615 636 0.90
8 17 0.085 10 7.9 1.8 1 22 656 677 656 680 0.91
9 17 6.6 8e+02 1.9 4.1 1 23 685 707 685 707 0.86
10 17 1.7 2.1e+02 3.7 0.4 1 23 723 748 723 748 0.95
11 17 0.17 21 6.9 2.5 1 23 760 783 760 783 0.96
12 17 0.0022 0.27 12.8 4.4 2 23 789 811 788 811 0.94
13 17 0.00033 0.041 15.4 2.1 2 23 815 837 814 837 0.94
14 17 0.56 68 5.3 3.3 1 23 843 866 843 866 0.91
15 17 0.012 1.4 10.6 0.5 1 23 871 893 871 893 0.98
16 17 7.3e-06 0.00089 20.7 2.2 1 23 899 921 899 921 0.99
17 17 0.009 1.1 10.9 0.2 1 23 927 956 927 956 0.88

Sequence Information

Coding Sequence
ATGGCAGTTAATTGTTCCACAAGCATGAGCATTTGTTTATATTGCAAAACAACTTCTGTAGCACAAAGCGAAAAAGAATTCCATGATATTTATGATGAGGTGGGTTTGGAACTGCAATTGCCACTTTTGGTGGAAACATATTTTCATGTTAAAATAGACAACAACTCTGATCAACGTTTGTGTGATGACTGTGTCAATCGTTTAATTGAGCTCTATGATTTGGCAGAGCATGCAAAACTGGAAAATGGCCAGAAATACTTGGATGAGCAGAAGGAAACCGAAGAATTTAAAGAACAAAAGGAAGAAGAATTCATTAATATTGTTTCGGAACAATTTAAAGAGAGCTTTCAAGAACATATTTCTACTCTTAAAAATGATAAGCAAAGTTGTCATTATAACACCAACCATGAAATGGAATGCAATCAGTTTTACAACGCTACAGATGATGATGAATCTTTCGTTACAGCAAGGAAAAATACGGAAATAATTTTGGATGCTAGAGTGTCAAAGGAAACTATTACCGATGCTAATGATCACATAATAGAAGAAAATATTGATTACAATATTGAAACAGAGAAAACTTCTAAATCGAATGCAATACTTGACAACGATATAGATGATACTATCGAAGAATATTATGTTGTAGAAGAACTTTCAAATGAATCAGTAGTTAAAGGTGAATCATTTGAAATCACAACTGATCTATGTGATCAAATTCAAGAAGAGCATGGATGCGAAGAGAAAACATTTAACGATGACACCACAAATAACTCTCACGGTGAACTTTATACAGACGAATTTGTTATAGAAGAGCATGTCGAAGACACTGATGAAGAATATGAAATTCAAGAAAGGTTTCAGTCCGTTCAAGAAGAAGACAGTAGTGAATTAGCATATGAATCAAAACAAGCTAATGAAAATATATTGGATGTTGACACTGATACTCTAACCTCTACTGTTAGTAGTGATGATATCAACTGTACCGAAGAGGAGTATTTAATTGAAGaaattgatTGTACTGAAGAGTATGATAGGGTAGACTTAAACGAATATTTAAATAGGGCAGTAAATACTAGATTTAGCGACTTGGAACTAAATTGGAAACTTGAATGTAAActttGCTCGGAAAAATACACCTCATTCCAAGATCTATTAAACCATGGTTGTATAATAGACTCAATGGAGCATCAGCAAACTTCTTGCATATACGAAGGATGTGAAGAAAATGCTAATGATTTGAATTCTTTAGCTAGACATTTAATACTGCAACACTTTCCTAAATTAGAAGAgaTATCTATATATAGTAAATGTCCCGATTGTGAAAGAACATTCTCTAATATAATACAGTTTAATAAACACTCCTGTTGTTGCAATATTAAAAGAAAGGCTGGATCCCAAAATTTATGTGCGgcttgtaatttaaattttaaatctttgaaaagATATATCTTCCATATGCAATTCCATCTAACGAATCACAGACCGAGGATTTGTTTAATATGCGGTTCTCTTTTTAACAActccaataaattttttgatcaCGTACAATACGAACATAACCAACAAGAATCTTGGGCATGTAAAATaTGTGATcgcttttttaaagaaaaagacgTATACGACAGCCACATGGAATCACATCGAGAAGCCAAATATAAATATGCCTGTTCATATTGTCCAAAAGAGTACACTAACAAAAGTGGAATAAATTTACATATGGAAGTTTATCACAATCATAAACATAAACCTCTACAATGTGAATATTGTGATAAAGAGTTCGTTAATAACCATTCATATCGTAATCATATAAAAGCCCATACTTCTGATGTTGAAGTGGAATCATATATTTGCTCTGTATGTGGTTTAATAACAAAAGACTTTGATACGATTAAGGATCATGTGGAAAAAGACAAGAATTCATCTTGTTTTTCGGCaattgtaaaaaatgaaatattatctCTGTGCTATACATGTGAAAATTgttctttagatttttttacaataccACATCTTAGGCAGCATCGTTTGTCCAGTACTCATAATGATAAAGTTTTCAATTGCGTCATTTGTCGTCGGAAATTTAAATCATTGCGTTACATGCGTTGTCATGCTACCAGTCACAAAGAATACGAAAAGAGGCAAGAAGCATTTCCAATAACTAGATATTATGTTTGCAATATTGGCCAATGCGGAGAATTCTATCTTTTGTGGTCTTCATTATATTATCATAAGCAACGTCGTCATAAAAcggaaaagaaattaaaaacggACGATGattttaaatgtcaattttGTCAGCAATTATGTACTTCAAAAATGTCTTTGGCTGTACATGTAGCCAGGCGTCATAATAATTCAAATATTCATTGCACGCATTGTAGTCAAACGTATAAAAGTCAAAAGCAACTACAAGACCATATTGATAAATTGCACGTGGAAGTCAAATGTgattattgtttcaaaaaatttaaaaatcgccgCAATTTGAGTATACACAATCAATCTGTGCATATAAATGAAAAGCGTTACTTCTGTCAACATTGTAATAAaggttatttttataaaagtgaaAAGGATGCCCATGAGAAACAGGTTCATTCGGAAATCTCGTATAAATGTGAATTATGCAATTTTGTAACCAACTATCCGAAGTCTTTAGACATTCATTTAGATAAACACATTAATCAACTCAAGTTTAAATGCACAATTTGTTCTAAATCTTTTGGCCGAAAGCAATTGTTAAATGATCATTTAAAGAGACATGAAGGTAAAAAGGGTTACAAATGCCGTGATTATTATAGTGATGCTGATTGTGATGCGGTCTTTATAACTTATAAATTACTAAAAACCCATATACAACAGGAACATAAAGGttcaaaaattttggaaaaagtaGCATCTAAACGTAAAAGAGTTGATTCTGTAAAAATTGACGACGATGTTATTGAATTTctagatgataatgatgatggcaATGAAAGCACTTATGGTAAAGGTCTAACAGATAGCtctaataaaagaattaaacatGTCAAATCTGATAATAATTCCATAGAAATTATGGTCGAAAATGATTTATTAGCAGCTAATAATGAATATATAGTACAATATCAGGATGTCATTAATAATATGTAG
Protein Sequence
MAVNCSTSMSICLYCKTTSVAQSEKEFHDIYDEVGLELQLPLLVETYFHVKIDNNSDQRLCDDCVNRLIELYDLAEHAKLENGQKYLDEQKETEEFKEQKEEEFINIVSEQFKESFQEHISTLKNDKQSCHYNTNHEMECNQFYNATDDDESFVTARKNTEIILDARVSKETITDANDHIIEENIDYNIETEKTSKSNAILDNDIDDTIEEYYVVEELSNESVVKGESFEITTDLCDQIQEEHGCEEKTFNDDTTNNSHGELYTDEFVIEEHVEDTDEEYEIQERFQSVQEEDSSELAYESKQANENILDVDTDTLTSTVSSDDINCTEEEYLIEEIDCTEEYDRVDLNEYLNRAVNTRFSDLELNWKLECKLCSEKYTSFQDLLNHGCIIDSMEHQQTSCIYEGCEENANDLNSLARHLILQHFPKLEEISIYSKCPDCERTFSNIIQFNKHSCCCNIKRKAGSQNLCAACNLNFKSLKRYIFHMQFHLTNHRPRICLICGSLFNNSNKFFDHVQYEHNQQESWACKICDRFFKEKDVYDSHMESHREAKYKYACSYCPKEYTNKSGINLHMEVYHNHKHKPLQCEYCDKEFVNNHSYRNHIKAHTSDVEVESYICSVCGLITKDFDTIKDHVEKDKNSSCFSAIVKNEILSLCYTCENCSLDFFTIPHLRQHRLSSTHNDKVFNCVICRRKFKSLRYMRCHATSHKEYEKRQEAFPITRYYVCNIGQCGEFYLLWSSLYYHKQRRHKTEKKLKTDDDFKCQFCQQLCTSKMSLAVHVARRHNNSNIHCTHCSQTYKSQKQLQDHIDKLHVEVKCDYCFKKFKNRRNLSIHNQSVHINEKRYFCQHCNKGYFYKSEKDAHEKQVHSEISYKCELCNFVTNYPKSLDIHLDKHINQLKFKCTICSKSFGRKQLLNDHLKRHEGKKGYKCRDYYSDADCDAVFITYKLLKTHIQQEHKGSKILEKVASKRKRVDSVKIDDDVIEFLDDNDDGNESTYGKGLTDSSNKRIKHVKSDNNSIEIMVENDLLAANNEYIVQYQDVINNM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-