Mcol003136.1
Basic Information
- Insect
- Meteorus colon
- Gene Symbol
- Zfy2
- Assembly
- GCA_030523125.1
- Location
- JAPYZG010000293.1:10933-18203[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.078 7.3 7.2 7.6 1 23 163 186 163 186 0.97 2 17 1.6 1.5e+02 3.1 0.4 2 23 204 225 204 226 0.93 3 17 1.5 1.4e+02 3.2 4.2 1 23 232 254 232 254 0.97 4 17 0.0012 0.11 12.9 0.7 2 23 260 281 259 281 0.97 5 17 0.0012 0.11 12.9 2.0 2 21 535 554 534 555 0.95 6 17 1.8 1.7e+02 2.9 1.0 1 23 624 646 624 646 0.82 7 17 0.16 15 6.3 1.3 1 23 857 879 857 879 0.95 8 17 0.024 2.3 8.8 0.4 1 23 887 909 887 909 0.98 9 17 0.089 8.3 7.1 1.0 2 23 1005 1026 1004 1026 0.95 10 17 5.9 5.5e+02 1.3 4.8 1 23 1108 1130 1108 1130 0.95 11 17 0.00057 0.053 14.0 0.3 1 23 1136 1158 1136 1158 0.98 12 17 0.029 2.7 8.6 0.3 1 23 1227 1249 1227 1249 0.97 13 17 2.6e-05 0.0024 18.2 0.4 1 23 1255 1277 1255 1277 0.97 14 17 0.0043 0.4 11.2 2.6 1 23 1326 1348 1326 1348 0.97 15 17 0.0012 0.11 13.0 1.7 1 23 1354 1376 1354 1376 0.99 16 17 0.09 8.4 7.0 0.7 2 23 1468 1489 1467 1489 0.97 17 17 5.5 5.1e+02 1.4 0.2 3 23 1498 1518 1497 1518 0.82
Sequence Information
- Coding Sequence
- ATGTCGGAGCCTTCAGCAATACTTCGGGCATTGAGACCAAGAACTTCACACAAAAGGAAATCATCACAAGAGCCGCGCCAAGTTGACGCGGCAGAGGGAGAAGAGGCAGATGGTTGTACAAGTCAAATGGACGATACAGGGATAGAGAACACGGAGACAACGGGTGGGGACGCAagtgatattgatattgatgctctcaatataaacaatgatGATAGGGAAGACAATGAAAATcgtgacaatgatgatgatgataataatgttgatgatgatgataatgatgatgatgatgacgatgacgatgatgatgatgatgatgagccGCGACTTACTATAAAAGAAGAACCGGAAGGATATTTTCCTGATGATGAAGTGATATGTGACAGGAGATACGTTTGTGAATCATGCGCGCCCGATATTGAATTCCCCACTTTAGTTGAATATTTGCAACATCTCAAGGATAAACATCAAAATAAGACAAAATGCCACGAATGTCCTCATTGCAATTTCATCTGTCAACATCCAAAGCGATTAACACGACATATCTTAACATCGCATAAAGAGATAGCTGCGAGTGATTCGTCAATATCTGagaatggaatatataatCGATGTTCGATGTGTACATTTATTGCTATAGATCAAGCAGACTTGATCGAACATAATAAACTTCATCACCTGAAACGGAGGTTTTTCCGCTGCTCAAAATGTCCGTACATGACCCACGTACGCGCACGATATACCAAGCATGTTAAATATCATTCTATGCCAATGATTAAGTGTGATGATTGCGATTTCCGTACGCCATATAAGTGGAATTTAGATCGACATACAAGAAACCATGGCGGGGGTGGAAAATTTCAATGTCGGGCATGTAATTTCACAGCCGATATACGTCAAAGTTTAACCGTTCATGAGACAAATCACCACGAACCACCTCTAGGACAAACCATCAGGAATATGAATGATGCACTTGAACGAAAACAACGAAGTGGTGCGAAACGATACAATCAAGTTGGTGCTAGCGATTTTCGCGACGTTCCCAGGACTTCAGACGCAACAAATTCTATCAACTCTAAATCACCAATGCAAATAGATGTCCCAGAGAGTCAAATAGAGGACACGTCTGCGATAGCTGGCGCTGAATGTATCGCGTTGAAGTGTGAGGAAAAAGGTTGTCAATTCATTACCGCATGGGATTCGGAGATGCAACGTCATCTGATGGAATCACACGCACCGTCACAATCGCCAAATAAATCACGTAAACCGATACCAATGTTGATTCCATTAAGTcctgaaaataaaactaataGTGCAATGACGAATGGTTCGACATCGAATTGTTTGAAAGTTCCGCGTGTGCGAGTGAGGCCAGAATTGGCGAAAATTGCAAGAGACACTGAAATAGCGAAATTATATGGCAATCGTGAGATAAAGGAGAGGTTAATGACGACGAGTGCGAATACGGGGTCATCACAGGTGATTGTAAGTAGCATGGAAGATTTAAAATGTTGGTGTACCTTTGAAGCGAATAGCATGGAAGAATTGTCCAGACATAGGATGACACATCACACTGCTCTCAGTGTGTCCGTTGGTGTTTCGCGCTGTCCAAAATGTCGAAGACGTTGTAAGAGCTCGACAGATCTTCAAGTGCATATGCAACTTTGTCAAGtgcaaaacaatttttcaatgataaacaGTAGTAGTCAGGAGAACACCCCCAATAGCGCAAGCTATATGGCTGCATCTCACTGTGGTGATTTTGAGTTTTCATTTCAAGGCGACTGGGACGGGGGTCCGCTTGTCGGTGGCCTCAATTCTTCCGGATCGTCGGTGGATGGTGCCTCAAACACATCAACACGACGAGTGTTTAAGTGTCCACACTGTCCATTTTGGGCATCTACTGCCAGCCGTTTCCACGTACACATTGTCGGACATTTGAATAGGAAACCATTCGAGTGTTCGCTGTGTCAATATAGATCGAATTGGAGATGGGACATCACGAAGCATATTAAACTAAAGGCAGCTCGAGATCCCGCGCACTTGACAGCCAAGGTTCTCATGACAGACGAGACTGGCAGGCGTAATTATTCCAAGTACAACAAATATCTGGCACAGATGGATCAACAAAATGATGATCCAACTGCAGAAGACTGTAGTACCAGCGAACATCGTGTAGATGAACCACTAAAAAAAATCGTTATCATGAGTGACTCGGACTATCCAGCGCCACCAGAATTAACGCCAGCCCCAAGTAGTAGTAAAAATGCCATGGATTCATCAGTTGTTTCAAGGCCACCACCGCCGCTCCAAGCGGCGCGAGGTCAGGGTCAATCGTTATTGAAGACGAGTCCATCAAACAATCCAACGAATGTCGCCATATCTGTATATTCGTCGAGTATTTCACCAACTGCATCAACGTCTGCCACAACCGAAGAAACAAAGCGTACACTTTGGAAATGCAAGCGATGTAATTTTCGTGATGCTAATAAGGAGATGGTGCTGTTTCATGTTAAGTCACATTATGAAACGGTTGACCAATCATCCAATAATGAAAACGCCAATTCATTCAGTTGTAATCATTGTCCATTCATCGCCAACAATGCAACGAGTTTGGCAATGCATCAAGTCCACCATCGACCCAATTTAGAGgcaatattcaaatgttatttGTGTCCTTTTTATGTCAGAACTAAAGCGGAACTTCTGGAACATGCACGTTTACACGGAGCAGAATTGGCAGCTGTGCATCAACGTTCTACTTCTACTACTGATTCATCACCGGCGAAATCTAAATCACCGAACCAATCAACTTCGCTGGATAACATTGCGAAAACGGATATTTCTGTAGAGGAGGTACCACGCGTTCATCCAGCAGATTCATCAACGAATGCGAACACCTCAAGTGGTAACAATGAAGCAGCACCACCACTATTATTGGATACACGTGCGTTGCCTGATACTCCTCTTGTTTGGGTCTCACGCGCGGACGGTTCTTTCgcgaaaatgttgaaatgtcGGTATTGCCCACATGTGTCGTCGCGTCGTGCTGAAGTACGCGATCACGAAACAATGCACTCAAACGCATTTTCTGGTGTTGGTTTACTGATCGCCTGTCCAGATTGTAGTTTCAGTTGTAATAAACGTGAAATAATGGATTCCCATGCTGACATGCACTTGGGTTCATTGGGAACAGTTCATTGTTTGGTGGACGATGGTCGCACTGACGCTCAACAACTTGACGATTTAACTACATTACTAGGTCTATCAAAAACACCAACTCTCGGTCCCGAGCCTGAATTACGTGATACACGTTTGGTATATTGTTGTAGTAAATGTCCAGCGCGTTTCCTCTGTGAAAAAGAACTTCGGATTCACATGCGATATCATTCAACTGAGCTTGCATATTCATGTGAATGGTGTTCGTATGCCGCCAGACAACCATCACATTTATTAGCACATCAGAAAGCGCATTCCAGTGATTATCAAGTACGTTCACGATCCTTATTATTAGAGTTCGGCCATTCTCAGAGATATCCACCGCCAAGAACAGCATGCGTTGAAAAATCTAATAAAGACAATAGTAAAAATATCGCGTGGATAGTTGTTGAATTATCCACAAATTCAGCCAACAACTTACCAAATAACTCGGGGAATGAGCAACGGAATAATCAAGTTTTCACGTGCGCTAAATGCCCAGCGCGATACTTCAAACTTGATGCACTCGAATATCATATGACACTCCATGGTTCGAATAATCGTTTTCAGTGTGAAGAGTGCGATTACTCTTCGAAAACGGcacaaaatttgatgaaacatCAGGTTGTTCACAGAAGGCATACAGAAGCGAGCGAACCGGCGGCAACTGCGCGTCTCCAAACACCGCCTGAACCACAATATGGAACATTCATGCGTGGTAATCCAAATTTTGTATATCAAGGATATTTACGAAATGGTAgattgaaggagaaaaaatacaagTGCCATAAGTGCCCATCGGCATTCGAAAAACGTGAACAGTATCGAGTACATCTGACATTGCACGGTGCTAAACAACGTTACCGTTGTGATACCTGCGATTATTCGGTCAAATATTATGCCAACTACGttcaacatttgaaaaaacacCAAGCCAGTGCTCAAGCACAAGCATCTCGTAGACAAATGGAGAGGAACATGGATGGCAATAAAGTTATCGGCGGCGATGAAAGcataaaaaatgtcaaaacaAGACGAAAATCAACAATTTCGTCAGCTGGGACTCATGGATTAAATACATCAACATCTACCAGCGCCGCAGCAATGTCGTCTGTATCGAATCAGGATAAACAATCGATGTTACTCATGCAAAAGAAAGGAACTAATATAGTAATGCAGTCTGAAACCAATGTTAAAATGTTACGTTGCCATGAGTGTCCATTTTCAGCAGTGGATAAAGATACGATTGATGCACATAAACGTCGCCATGGGCTTGAGCGTCTAACGCCACCGTGCCCTCATTGTAATTATGTACCGCGCAAAGATGAAAATATCGGTGATCACATCAGATTACATTTCACGCGCTTATACAAGCCTGAATCTTATTTAGTCGTTGAATTACTATCATTGACaatgcaaaaatttaattcaaataagaaAGATAAGCAAAaagataatgaattattgttttctgAATGTGGTGATGGGAAATATTTGCCAGTCGCCAATGCAAGTTCACTGCCAATCGGTGTGACAAATGAGAATGGATTCCAAGAAAAAGTTATCGTTGATCCAAATACCGGTGAAACGACACATCGTTTTtga
- Protein Sequence
- MSEPSAILRALRPRTSHKRKSSQEPRQVDAAEGEEADGCTSQMDDTGIENTETTGGDASDIDIDALNINNDDREDNENRDNDDDDNNVDDDDNDDDDDDDDDDDDDEPRLTIKEEPEGYFPDDEVICDRRYVCESCAPDIEFPTLVEYLQHLKDKHQNKTKCHECPHCNFICQHPKRLTRHILTSHKEIAASDSSISENGIYNRCSMCTFIAIDQADLIEHNKLHHLKRRFFRCSKCPYMTHVRARYTKHVKYHSMPMIKCDDCDFRTPYKWNLDRHTRNHGGGGKFQCRACNFTADIRQSLTVHETNHHEPPLGQTIRNMNDALERKQRSGAKRYNQVGASDFRDVPRTSDATNSINSKSPMQIDVPESQIEDTSAIAGAECIALKCEEKGCQFITAWDSEMQRHLMESHAPSQSPNKSRKPIPMLIPLSPENKTNSAMTNGSTSNCLKVPRVRVRPELAKIARDTEIAKLYGNREIKERLMTTSANTGSSQVIVSSMEDLKCWCTFEANSMEELSRHRMTHHTALSVSVGVSRCPKCRRRCKSSTDLQVHMQLCQVQNNFSMINSSSQENTPNSASYMAASHCGDFEFSFQGDWDGGPLVGGLNSSGSSVDGASNTSTRRVFKCPHCPFWASTASRFHVHIVGHLNRKPFECSLCQYRSNWRWDITKHIKLKAARDPAHLTAKVLMTDETGRRNYSKYNKYLAQMDQQNDDPTAEDCSTSEHRVDEPLKKIVIMSDSDYPAPPELTPAPSSSKNAMDSSVVSRPPPPLQAARGQGQSLLKTSPSNNPTNVAISVYSSSISPTASTSATTEETKRTLWKCKRCNFRDANKEMVLFHVKSHYETVDQSSNNENANSFSCNHCPFIANNATSLAMHQVHHRPNLEAIFKCYLCPFYVRTKAELLEHARLHGAELAAVHQRSTSTTDSSPAKSKSPNQSTSLDNIAKTDISVEEVPRVHPADSSTNANTSSGNNEAAPPLLLDTRALPDTPLVWVSRADGSFAKMLKCRYCPHVSSRRAEVRDHETMHSNAFSGVGLLIACPDCSFSCNKREIMDSHADMHLGSLGTVHCLVDDGRTDAQQLDDLTTLLGLSKTPTLGPEPELRDTRLVYCCSKCPARFLCEKELRIHMRYHSTELAYSCEWCSYAARQPSHLLAHQKAHSSDYQVRSRSLLLEFGHSQRYPPPRTACVEKSNKDNSKNIAWIVVELSTNSANNLPNNSGNEQRNNQVFTCAKCPARYFKLDALEYHMTLHGSNNRFQCEECDYSSKTAQNLMKHQVVHRRHTEASEPAATARLQTPPEPQYGTFMRGNPNFVYQGYLRNGRLKEKKYKCHKCPSAFEKREQYRVHLTLHGAKQRYRCDTCDYSVKYYANYVQHLKKHQASAQAQASRRQMERNMDGNKVIGGDESIKNVKTRRKSTISSAGTHGLNTSTSTSAAAMSSVSNQDKQSMLLMQKKGTNIVMQSETNVKMLRCHECPFSAVDKDTIDAHKRRHGLERLTPPCPHCNYVPRKDENIGDHIRLHFTRLYKPESYLVVELLSLTMQKFNSNKKDKQKDNELLFSECGDGKYLPVANASSLPIGVTNENGFQEKVIVDPNTGETTHRF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -