Basic Information

Gene Symbol
ZNF236
Assembly
GCA_030523045.1
Location
JAPYZF010000509.1:11018-19003[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 4.2e-05 0.0036 17.6 1.0 2 23 53 74 52 74 0.97
2 24 3.2e-05 0.0027 18.0 2.0 1 23 95 117 95 117 0.98
3 24 3.3e-05 0.0028 17.9 2.1 1 20 123 142 123 145 0.93
4 24 2.8e-05 0.0024 18.2 0.7 1 23 151 174 151 174 0.96
5 24 0.0011 0.099 13.1 1.9 1 23 184 207 184 207 0.97
6 24 2.2e-07 1.9e-05 24.8 1.8 1 23 319 341 319 341 0.98
7 24 1.7e-05 0.0015 18.8 2.9 1 23 347 369 347 369 0.99
8 24 0.0019 0.17 12.4 1.6 1 23 375 398 375 398 0.95
9 24 9.7e-07 8.3e-05 22.8 1.1 1 23 402 424 402 424 0.99
10 24 0.00027 0.023 15.0 3.6 1 23 480 502 480 502 0.98
11 24 3.6e-07 3.1e-05 24.1 1.3 1 23 508 530 508 530 0.99
12 24 1.5e-05 0.0013 19.0 1.3 1 23 536 558 536 558 0.98
13 24 0.00039 0.034 14.5 7.4 1 23 564 586 564 586 0.98
14 24 3.9e-06 0.00033 20.9 1.7 1 23 906 929 906 929 0.95
15 24 0.014 1.2 9.7 2.2 2 23 951 972 950 972 0.97
16 24 5.7e-05 0.0049 17.2 4.3 1 23 978 1000 978 1000 0.98
17 24 0.05 4.3 7.9 0.7 2 23 1010 1031 1009 1031 0.97
18 24 8.1e-08 7e-06 26.1 1.4 2 23 1108 1129 1107 1129 0.98
19 24 0.021 1.8 9.1 5.0 1 23 1135 1157 1135 1157 0.98
20 24 6.2e-05 0.0053 17.1 4.3 1 23 1163 1185 1163 1185 0.97
21 24 0.00019 0.016 15.5 3.1 1 23 1191 1213 1191 1213 0.99
22 24 0.0002 0.017 15.5 1.9 2 23 1460 1481 1459 1481 0.97
23 24 3.1e-05 0.0026 18.0 4.0 1 23 1487 1509 1487 1509 0.98
24 24 3.3e-06 0.00028 21.1 5.8 1 23 1515 1538 1515 1538 0.98

Sequence Information

Coding Sequence
ATGACGCTCGCAGTTGATTGCATGAATTTTGCTCTTCTTATTGTTTGCTCCCGTGTATTCCATTTTGCTCTTGGACTCAGCGCACAATATTACAAGGCGCAATTGGATGCACACTTGAAACTTCATAATGAGAAATGGTCGACCGATGACGTAAAAAAGTGCAAGCTCTGCAACAAACAATTCACACAGCCTGCGCTCTATCGAGTTCACATACGTGACCACTATAAGCTGCAGACGAAGATAATGAAGCAGACAAAGAGAGGACCAACACATAAAACTTTACATAAGTGTCGAATATgcttgaaaatattccaaaaacCAAGTCAATTGATGAGGCATATTAGAGTTCATACAGGAGAGAGACCATTCTCGtgtAATACTTGTGACCGTACATTTACGCAGAAGAGCTCATTACAAATCCACAAATGGAAGCACGTTGGTGTACGGCCATTCACTTGTGTTCATTGCAACGCAAAATTCAGTCAAAAAGGAAATTTAAATGCACACGTGGCGAGGGTGCATAATCCACCGGAAGACGGTGGACCCGTTTATTCTTGCATGCTATGCTCATGTGCTTTCAAACGACTCTCGAGTTTAggtattcatatgaaaaaaatacacgcATATCCAATAGAAAAATCGAAATGCGACAGCTCAACAGAAGCgattaaagatgaaaataaatgtgaatcaGAGTTGAAAAATCCAAGCGTTAAAAATAATACTACGCCGACTGattcagaattaattgataaacaaagAAGTGATATATTACAAGAAGCTTTAAAAAAAAGTGGATTTtcaaataaagataaaagtaATGCTATtgAAGTAACTGACCCTTCAAAAGATAATTTCGATACATCTTATGTTACACTATTGGACAGAACACCTGATGGTGCATTAAggcggtatataacaataaaacagAGGAGTAATGGCAGTATAAAATGGTACGCGTGTAATTATTGTCATAAGGAATTTAAGAAGCCATCTGATCTCATACGACATTTACGAGTACACACACAAGAAAAGCCATACAAGtGTCCACATTGTTACCGCTCATTTGCACTCAAGTCAACGATGCTCGCCCACCAGCGTACTCATACAGGCGTTAAGAAATATGCCTGCGGTATATGTGGCAAGAAATTCGCTTGTCATAGCAGCTTGAATGCTCACACGAgCTCTGCCCACGTGcaacaatataaatgcaaTGTATGTGAGAAGACATTTGCCACTAATAATCTTCTCAAATCTCATGCAAGAACTCATACGAAATCAAAGTCAACAATATCACCAGATGCTGAAGCATTAATACCAAAAATTGTATTGGAGGAACCATTAATGATAAGTGATGCGGGTAATAAAATAAGTGTTGCACATATACAATCTAAACAGAAACAAGCATTAGATGATAGAGAAGATAATGATAGACCACATAAATGTTGGGTTTGTCCAGCTGCATTTCGCAAAATAAGTCATTTGAAGCAGCATTATCGTCGTCATACTGGCGAACGGCCATTCAAATGCCCTAAATGCGATAGACGTTTTACATCGAATAGCGTTTTGAAAGCACACTTGCAAACGCATGAAAAATCACGACCATACAATTGTAATGTATGCAATGCCAAGTTCTCAACTCAAAGCAGTATGAAAAGACATTTGGTTACGCACAGCAACAAACGACCATTCATGTGTCCATACTGTCATAAAACATTCAAAACGACTGTTAACTGCagaaaacatatgaaaattcatagaaCTGAACTTGCACAACAGCAactagaaaaagaaaaagcacaaatttcatcaacagCTGAAAGTTCTATTTCACCAATAGCAATGAGTGAGACTTTGCATTTACACGACgatatttcaaatacatttcaacaaaatataagtaCAGATTTTGCCCAAGCATTCAGCGATCAATTAACATCAATGGCGgcagttgataaaaataatttgtcggGGGTGGATGTTAATGTGACGGCTAATACGATAACGGGAAATTTAGCAGTTGTTGAGGCTGATAATATGGAAGCCACTCAGACATTACATGCGGATGAGACTGGAACAATTACTCTACCAAATTATTCGGGAGATCAAACGCTCACACCGGAGAGTATTCGAGAGCTTGAAGAGACACTGAATCaacaattgttcaatataGGAATTAATTCAGGATtgggaaataatttatcacgTCAAATCACTGATGCGAATGGTGAATGCATAACAGAAGTACGTGATCCACCAGTATTGAACATTATTTACGATAATTCAAAACAAATGGAACATCATCAGCAATCAACTAATGTAAATTcgatcaattcaaatatatttccaccAAATTTCGATACATTCGACATTAGCCAAATTACACTTCAAGCCGATACAGAAATGGATATTGGAATTAATGCAGCGAATTCAACAAGTATGGCAAGTATATTACCAAGGTCTGCGCAAGAGCAACAACATTTATTAGTACCTGTAACCAATCGAAACACACTGCAGAATAATATCCAAACAAAAGAGCCAACACAACAATTAGTTGTCGTTAATAATTCGTCACAAgcatttcatcaacaattttcaaagAATCAACCGACTTTCTTGAAATATCCAAAAATTATTGCCAAAGCTGATACAACAATTGACACCGATATTCTGAATATGCAAcagcaaaataatattattgagcATAATGAAGGTTTTACTTGTAATTATTGTGATACAATATTCAAACGAGCGCATGATTTGAAATCTCATATGGAGCTGATCCATATGTCTgctaattttaaattaaacatggaaaattacggcgatattgaaaatgaaaatggattgCAATGTCATATGTGTTATAAAAAAGGTTTTGATGCATCAACATTGAAAGATCATTTAACTACTCATCGAGGcacaaaagaatttcaatgCACTGAGTGTCATTTAAAATTCTGTACTAATGGTGGATTAAGTCgccatataaaaattcatacgactaaaacaattaatacatGTTGGACATGTACACAATGCTTTGATACATTTCCGAATGAAATGCAATTGAGATTGCATGAGAAAACGCATGAGAATATTGGTGGTGTTGTGCCACATACAATTGAATGGAGTGTAGGAAAAATTGAACCAGACAGTTCGCAACAAATAGAATCATCGATTGATACAAAATTGCTGACGGTGAATGGCACAAACACAGCGATAACAGGAAGAATTTTGCTCAATGCTGTAGATTCTGATTTCGATCTTAAAACCACCATCAATCAATCATTggatggaaacaaaaaagaatatgacaacaaatgtaaatattgcCCAAAAACATTTCGGAAACCCAGTGATTTAATACGACATGTGAGGACACACACTGGCGAACGTCCATATCGAtgtgaatattgtgaaaaaagttTTGCGGTCAAATGTACATTAGATTGTCATATGAAAGTTCACacaagcaatgaaaaattctgttgTCACGTTTGTAATCGTCTCTTTGCTACAAAAGGTAGTTTAAAAGTCCATATGCGTTTGCATACTGGCGCAAAACCATTCAAATGTTCGGTTTGTGATTTGAAATTTCGGACATCTGGTCATCGAAAAGTTCATTTACTCACTCACATgcgtgagaataaaaataatgatgtgaaaaataaaaaaacaaaaggaagaaCCGattcagaattgaatgaactGTCGACATCAGCAGCGTTGCTGTcacaaattaatgataaatcacTGGAAAATTCGGGGGATATTAATGGCGATCATACATCGGTAGTAGTGAATGGAACAAATTTGAACGCAACATCGGATTATACAAATTTGGACACAATAACAATAGATGCAACTGGAATATCTGATCAATTAACATTCAATCCCGATGGTACgatattaaacaataattcgATATTATCGGTTAATGAGAGCAATCAACTCGTTGctgatttacattttttaattgcgAGTGGTCTTGTGACAATCCAAACAGATGAAGCATTATTGCCTCAATTGAATTGTTCTGATACGAATATTAATCATGATCATTCGACAACACATACTTTAGTTGCTTCAAATGCTTTAGAACAATCAGAAAATAATGTCATTATCAGTACACAAATGGGAAATATACAAACATCACAACAGCAATTGTCGGAGGCGACATCACAATTGCAATTGAGCGATGTTATGGCAATGGTTGAGATGCCAACTGTTGACTCAGTTAGGGTAATGAAATCGTCAGATGGTCAagcaataacaacaacaacaacaacaacatcaacaacaacaatgatCACCACCAAGCCGGGAATAAAATCGAACGGGAAAATAcaaggaataaaaattcctcCGAAAAAAGAATGCGATATTTGTGGGAAAACATTCATGAAACCCTGTCAAGTTGAACGTCACAAACGTATACACACCGGTGAACGCCCATTCAAATGCGAATTGTGTTCAAAATCATTCGCGCAAAAAACGACATTACAAATACATCAGAAACATCATACGGGTGATAGGCCATATTCCTGTCCACATTGTGATTATTCATTTACCCAGAAGTGTAACTTACAAACTCATCTCAAACGTGTACACCAATTGGAAACTatggaggggaaaaaaatgcgacgcaatcaaaatataatgagTGCTAAATTATATCATGACAGTAATAATACTAATTTAGACGATAATCGAATGCCTAATCTGGATGATTTATCTTTCGTTGAATTGttgaagtga
Protein Sequence
MTLAVDCMNFALLIVCSRVFHFALGLSAQYYKAQLDAHLKLHNEKWSTDDVKKCKLCNKQFTQPALYRVHIRDHYKLQTKIMKQTKRGPTHKTLHKCRICLKIFQKPSQLMRHIRVHTGERPFSCNTCDRTFTQKSSLQIHKWKHVGVRPFTCVHCNAKFSQKGNLNAHVARVHNPPEDGGPVYSCMLCSCAFKRLSSLGIHMKKIHAYPIEKSKCDSSTEAIKDENKCESELKNPSVKNNTTPTDSELIDKQRSDILQEALKKSGFSNKDKSNAIEVTDPSKDNFDTSYVTLLDRTPDGALRRYITIKQRSNGSIKWYACNYCHKEFKKPSDLIRHLRVHTQEKPYKCPHCYRSFALKSTMLAHQRTHTGVKKYACGICGKKFACHSSLNAHTSSAHVQQYKCNVCEKTFATNNLLKSHARTHTKSKSTISPDAEALIPKIVLEEPLMISDAGNKISVAHIQSKQKQALDDREDNDRPHKCWVCPAAFRKISHLKQHYRRHTGERPFKCPKCDRRFTSNSVLKAHLQTHEKSRPYNCNVCNAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTTVNCRKHMKIHRTELAQQQLEKEKAQISSTAESSISPIAMSETLHLHDDISNTFQQNISTDFAQAFSDQLTSMAAVDKNNLSGVDVNVTANTITGNLAVVEADNMEATQTLHADETGTITLPNYSGDQTLTPESIRELEETLNQQLFNIGINSGLGNNLSRQITDANGECITEVRDPPVLNIIYDNSKQMEHHQQSTNVNSINSNIFPPNFDTFDISQITLQADTEMDIGINAANSTSMASILPRSAQEQQHLLVPVTNRNTLQNNIQTKEPTQQLVVVNNSSQAFHQQFSKNQPTFLKYPKIIAKADTTIDTDILNMQQQNNIIEHNEGFTCNYCDTIFKRAHDLKSHMELIHMSANFKLNMENYGDIENENGLQCHMCYKKGFDASTLKDHLTTHRGTKEFQCTECHLKFCTNGGLSRHIKIHTTKTINTCWTCTQCFDTFPNEMQLRLHEKTHENIGGVVPHTIEWSVGKIEPDSSQQIESSIDTKLLTVNGTNTAITGRILLNAVDSDFDLKTTINQSLDGNKKEYDNKCKYCPKTFRKPSDLIRHVRTHTGERPYRCEYCEKSFAVKCTLDCHMKVHTSNEKFCCHVCNRLFATKGSLKVHMRLHTGAKPFKCSVCDLKFRTSGHRKVHLLTHMRENKNNDVKNKKTKGRTDSELNELSTSAALLSQINDKSLENSGDINGDHTSVVVNGTNLNATSDYTNLDTITIDATGISDQLTFNPDGTILNNNSILSVNESNQLVADLHFLIASGLVTIQTDEALLPQLNCSDTNINHDHSTTHTLVASNALEQSENNVIISTQMGNIQTSQQQLSEATSQLQLSDVMAMVEMPTVDSVRVMKSSDGQAITTTTTTTSTTTMITTKPGIKSNGKIQGIKIPPKKECDICGKTFMKPCQVERHKRIHTGERPFKCELCSKSFAQKTTLQIHQKHHTGDRPYSCPHCDYSFTQKCNLQTHLKRVHQLETMEGKKMRRNQNIMSAKLYHDSNNTNLDDNRMPNLDDLSFVELLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00997202; iTF_01560614;
90% Identity
iTF_00997202;
80% Identity
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