Basic Information

Insect: Metallyticus violacea
Gene Symbol: topi
Assembly: GCA_030762175.1
Location: CM060832.1:6389955-6393012[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.043 5.2 9.5 0.1 1 23 161 183 161 183 0.98

2 14 0.058 7 9.1 1.3 2 23 190 211 189 211 0.96

3 14 0.042 5.1 9.5 3.1 1 23 217 239 217 239 0.94

4 14 0.0038 0.46 12.8 1.8 1 23 245 267 245 267 0.88

5 14 5.7e-06 0.00069 21.7 0.7 1 23 271 293 271 293 0.99

6 14 1.1e-05 0.0013 20.8 2.4 1 23 299 321 299 321 0.98

7 14 0.0021 0.25 13.6 8.4 1 20 327 346 327 349 0.95

8 14 0.0075 0.91 11.9 0.6 1 23 355 377 355 377 0.97

9 14 5.2e-06 0.00063 21.8 0.6 3 23 387 407 386 407 0.98

10 14 4e-05 0.0049 19.0 3.1 1 23 413 436 413 436 0.97

11 14 2 2.4e+02 4.2 5.7 1 23 442 464 442 464 0.96

12 14 0.00049 0.06 15.6 3.4 1 23 470 492 470 492 0.98

13 14 0.00013 0.016 17.4 2.7 1 23 498 520 498 520 0.98

14 14 1.3e-06 0.00015 23.7 1.1 1 23 526 548 526 548 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.043	5.2	9.5	0.1	1	23	161	183	161	183	0.98
2	14	0.058	7	9.1	1.3	2	23	190	211	189	211	0.96
3	14	0.042	5.1	9.5	3.1	1	23	217	239	217	239	0.94
4	14	0.0038	0.46	12.8	1.8	1	23	245	267	245	267	0.88
5	14	5.7e-06	0.00069	21.7	0.7	1	23	271	293	271	293	0.99
6	14	1.1e-05	0.0013	20.8	2.4	1	23	299	321	299	321	0.98
7	14	0.0021	0.25	13.6	8.4	1	20	327	346	327	349	0.95
8	14	0.0075	0.91	11.9	0.6	1	23	355	377	355	377	0.97
9	14	5.2e-06	0.00063	21.8	0.6	3	23	387	407	386	407	0.98
10	14	4e-05	0.0049	19.0	3.1	1	23	413	436	413	436	0.97
11	14	2	2.4e+02	4.2	5.7	1	23	442	464	442	464	0.96
12	14	0.00049	0.06	15.6	3.4	1	23	470	492	470	492	0.98
13	14	0.00013	0.016	17.4	2.7	1	23	498	520	498	520	0.98
14	14	1.3e-06	0.00015	23.7	1.1	1	23	526	548	526	548	0.98

Sequence Information

Coding Sequence: ATGCATGTTGCGGAAAGATTATCGTTGCATAATGAAATTCAAGAAGATCCAAATGTTGGATCGGCGGCAATGAAAACAACACTTAAAGAAAAACCTGACGAGTGGGGTATAGTGGAATTACCagctccatttctgtcaaaagtgATTGAAGACTCAGCAGGAATCTGTGGTGCAGAACCTGTAGCTTCCAGCACAATTCAGCTCCAGCCCATAAGGCAATTTCTCACGACTTGGTTGCAGCAAGGTGATGAATCACCTGGCAATAAAGAAGAATGTGAAGAAACAACGTTGTTTTGCAACGACGATTTTGCAGACGAAAGTTCCCATATCTGTCATTGTGAGATGtgtgataaatattttcatgcttCAAAAGAGCAATTTGCTGCTCATATAATCGAGCACAGTGTACTGCTTTCTGAAGAAGGGTCCGTTGTAACCGTGAACAGCACAGAACAGTTGCAGAGTGAGACAACAAAAGCATACAGCTGCAGTTTCTGTGGTGCGATATCAAACTCTGAACAAGATTTTGCTTCTCATTTAAATATCCATGTTTCCAAACAGccaataaaatgtaacttttgtgAGAGTACGTTCAAGACCTTGTTGGAAATGAAAACACACGAAAGAGAACATAAAAATGAGAATCCATTTCACTGTAAATACTGTGAGGCAAAATTTCCTTCTACTACAGAGCTTCTCAAGCATTCTTCATACCACAGAAACAGACCAGGCTTTGTATGCAAGACATGTGGGAAAAAATTCAAGACACTGGCCGACTTTACATTTCATTCAGAGATGCATAAAAATCCATACAAATGTTTGGTTTGTGAAAAAGCTTTTAAAGATTATACTTCTTTGATGCGACATTTGAATGTTCACCAAAGTGGTGCCATGTACGTGTGTGAAAAGTGCGGGAAAGAATATAGGAGCCAGTCGCACTTTCTAGATCATCTCAAGTTGCACACAGGTTATAAATCATTTGTCTGTCACAAATGTGGGAAGAACTTCTACAATTTTAACAACTTGCAGCGTCACTTGCATTGTCATTCAGATCAGCAGTGTTTTATGTGTGCAAAATGTGGACAGAAGTTCCGCTGGTACAAGAATCTCGCTGCTCATAGCAAGGTGCATGATACAGAACGAGGGGCAGACGCTATTTGTGATGTTTGTGGGAAACAGCTTTCCAACAGAGATAAACTGAAAGTGCACATGCGTACCCATACTGGAGAACGGCCATATGCCTGCGAACATTGTAACAAGAGATTCACACAGAAGCCAAGCTTAAACTACCATGTCAGCACAAAACATGGTGGTCCTCTCAATCATGTCTGCGATATCTGTCAATGCAGATTTCCTTCAAAACAGGCCTGTGACAACCATCGCAGAATACATACAGGAGAGTGCCCATTTAAATGTACCATGTGCCCAATGTCATTCCGTTCAGCAAACTGTCTTTACTCGCATACCAAAATTCACCTGAACATCCGCACATACATATGTAGCACTTGTCAGAGAAGATTTGCAAAGAAATCTCAACTGGATAGTCATTTCCGAACGCACACAGGAGAAAGACCCTTTACTTGCAACGTGTGTGGGAAAGCCTATACACAGAAGTGGAATATGGTGAAGCATAGAAGATCTCATGAAGCTGAACAACAAACCAATGGACCACAGTACTCTTCACCTTTGGAGTCATCTTTCTAG
Protein Sequence: MHVAERLSLHNEIQEDPNVGSAAMKTTLKEKPDEWGIVELPAPFLSKVIEDSAGICGAEPVASSTIQLQPIRQFLTTWLQQGDESPGNKEECEETTLFCNDDFADESSHICHCEMCDKYFHASKEQFAAHIIEHSVLLSEEGSVVTVNSTEQLQSETTKAYSCSFCGAISNSEQDFASHLNIHVSKQPIKCNFCESTFKTLLEMKTHEREHKNENPFHCKYCEAKFPSTTELLKHSSYHRNRPGFVCKTCGKKFKTLADFTFHSEMHKNPYKCLVCEKAFKDYTSLMRHLNVHQSGAMYVCEKCGKEYRSQSHFLDHLKLHTGYKSFVCHKCGKNFYNFNNLQRHLHCHSDQQCFMCAKCGQKFRWYKNLAAHSKVHDTERGADAICDVCGKQLSNRDKLKVHMRTHTGERPYACEHCNKRFTQKPSLNYHVSTKHGGPLNHVCDICQCRFPSKQACDNHRRIHTGECPFKCTMCPMSFRSANCLYSHTKIHLNIRTYICSTCQRRFAKKSQLDSHFRTHTGERPFTCNVCGKAYTQKWNMVKHRRSHEAEQQTNGPQYSSPLESSF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -