Basic Information

Insect: Metalampra italica
Gene Symbol: THAP3
Assembly: GCA_949699065.1
Location: OX452998.1:3889419-3900574[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.092 5.3 8.0 0.5 1 23 384 406 384 406 0.97

2 10 0.03 1.7 9.5 0.8 1 23 413 436 413 436 0.93

3 10 0.45 26 5.9 0.2 1 23 440 462 440 462 0.92

4 10 0.0049 0.28 12.0 1.0 1 23 467 490 467 490 0.98

5 10 0.0033 0.19 12.6 0.7 1 23 494 517 494 517 0.96

6 10 0.98 56 4.8 0.1 2 21 530 549 530 550 0.86

7 10 0.19 11 7.1 0.2 2 23 607 629 606 629 0.96

8 10 0.011 0.63 10.9 0.5 2 20 645 663 644 666 0.92

9 10 6.5e-06 0.00037 21.1 2.5 1 23 672 694 672 694 0.99

10 10 0.00036 0.021 15.6 1.1 1 20 701 720 701 722 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.092	5.3	8.0	0.5	1	23	384	406	384	406	0.97
2	10	0.03	1.7	9.5	0.8	1	23	413	436	413	436	0.93
3	10	0.45	26	5.9	0.2	1	23	440	462	440	462	0.92
4	10	0.0049	0.28	12.0	1.0	1	23	467	490	467	490	0.98
5	10	0.0033	0.19	12.6	0.7	1	23	494	517	494	517	0.96
6	10	0.98	56	4.8	0.1	2	21	530	549	530	550	0.86
7	10	0.19	11	7.1	0.2	2	23	607	629	606	629	0.96
8	10	0.011	0.63	10.9	0.5	2	20	645	663	644	666	0.92
9	10	6.5e-06	0.00037	21.1	2.5	1	23	672	694	672	694	0.99
10	10	0.00036	0.021	15.6	1.1	1	20	701	720	701	722	0.95

Sequence Information

Coding Sequence: ATGAGGTGCAGCGTGCAGAACTGCAGCAATGACACGAAACGTACTACAAAAAGCCATGGAATTACCTTTCACATGTTCCCAAAAGAGCCGAACCTGCGCACGGCCTGGATAGAAGCCCTAGGCATGCTGGACTGGGAGCCCCGAGACCGCAGCACAATATGCTCTGAGCACTTCCGCAACGATGACTTCTATCAGACCAAGTGCGGCCTCCGGAAGATCAAGAATGGAGCCGTCCCTGTTGTAGAACAGAGTTCTACAGTTGACCTGGAGGCACCAGCAGCTCTAAGGGTATGCAGAATATGCCTGGCAATGGACACGAGAATGTACCACATACGGGAGTACAGACTGGACCAGCTGTACGAACAAGTCATTGGTGCCACCATGAGTGAAGAAGACAAGCTGCCGCAGAAGGTGTGCTGGGAGTGCGCGCAGCGGCTGAACAGCTGTTCCAAGTTCAGGCACAAGGGGCAGCGGAGTCAGGGCCTGCTTATGGACATGCTTCTTACCAGTCACTACATCACAATAAGAGATATAAAATCAATTAACCGAACCCATACCCAGTTAAAAACAAGCTTGATATCAAAGTATTACGAACCAAACGACTATGACATCCACATACACGACAACCAAGTGTTCGTCAAAACCGAGGAGCATGGAGAAACGAATGAACTTGAGGAAGACGAGGAAGAATTCAAAGAGAACGGAGAACCCATACCGCCTATAATGGAAGTGGAGATAGTGAAAGATGAGCAAAGCAATTCGGATATATACTTCGATGAATTTCACGATAATTTCGACGAATCCGAAGACGATAAGAAACTGAGCGAAGTTGTGTGCGAAAAGGAGAGGGAAGTGGGCGAAAAGGGGGTGAGAATAAAGACTAAAGTGAGGAAATTGAAGAAGAAGAAGTTGAAATTGGAGAAGAAGGTGAAAATGGCGAGAGTGGTGAAGAAAAGGGAAGCGATTAGGGTGGATGAAGATGATGATCCTTCAACTACGATGGACAAGTATAAAAAATCCGATGTGAAACGAAGAAAAACCCAAGACGGTCTGGACGAGTCCCTTTTCAATATATGCACGTTGACGTACGACGAGCAGATAGCGGAGATACAGAAGCGGCAGGAGACGCCGGCGTATCGGAACGCGCCGTTCAAATGTTCTATATGTTACAGAGGCTTCATGATCAAGGATAGGTACGATGCGCACATCATCAGGCATAGTGAGgcAAGTGGTGCGTACGAGTGCTTTATTTGCAAGACTAGACTTAAAACCGGGCGCGCCCTGCGCAAACATCTCACTGCCCAACATACCGAGAAGTTTAGCTGTAAGGGCTGTCCATTCGTTACAAGGAATAGaggTGTAGCGAGGGAACACGAAAAATGGCACGCCGGTGCTAAATACCAATGTCCACATTGTCCAAGTGAATtcgaCAAGCTAACAACATACATGGGCCATATTCGCATAAAGCACGTGTCGGACTTCGTGTGCGAACTGTGCGGGTACACGTTCGTGAGCAAGAAGGGGATAGATgtacacaaaaaaaagaaacacagACTCGTCGATAAAACGGTGCCGTTGGAAGGTCCGTACTGCGAGGTGTGCGACGTGACATTCGTATCGGAGGAAGCTCACTCCAGGCACCTGAAGCTGTCTTCACGCCATAGCAGTGACAATGATCCCAACCGCATCAGGAACGACTCGCAGAGCATGAACGCGGAGCGTCACGGGCGCGTGGTGCGGCGCATCGAGCGGCGGCCCGtcatacacccgcgggagccCGGCGACCGCGAGCGCAGGCCCGACCCCGGCGGGCCGGTCACCTGCGAGCAgTGCGGCGTGCAGCTGCGCGACCTGCGGCTGTACGCGCAGCACTTCCGACGCGCGCACCCCGACAAGAACCGCACCAAGTACCCCGCCATGAAGACGCCCTGCATGTGCGAGCAGTGCGGCAGGATCTTCCAGAGCATGGCTCTGCTGAAGGACCACATGTGGGTGCACACGGGCGAGAAGCGGTTCAAGTGCGACCGCTGCGACAAGTCCTTCACGCAGAAGACCAACCTCGTGTTCCACATGAGGGTGCACAGCGCGTCGCGGCCGTCGTACGAGTGCCCGCTGTGCGGGAAGCACTTCGCCTTCTACAACAACCGGCGGCGGCACATGTTCGTGAGTACATTTTCGCGCTTTGACCGTGATTGGCCTAGAAGGACGTtgcttccagggccgtaa
Protein Sequence: MRCSVQNCSNDTKRTTKSHGITFHMFPKEPNLRTAWIEALGMLDWEPRDRSTICSEHFRNDDFYQTKCGLRKIKNGAVPVVEQSSTVDLEAPAALRVCRICLAMDTRMYHIREYRLDQLYEQVIGATMSEEDKLPQKVCWECAQRLNSCSKFRHKGQRSQGLLMDMLLTSHYITIRDIKSINRTHTQLKTSLISKYYEPNDYDIHIHDNQVFVKTEEHGETNELEEDEEEFKENGEPIPPIMEVEIVKDEQSNSDIYFDEFHDNFDESEDDKKLSEVVCEKEREVGEKGVRIKTKVRKLKKKKLKLEKKVKMARVVKKREAIRVDEDDDPSTTMDKYKKSDVKRRKTQDGLDESLFNICTLTYDEQIAEIQKRQETPAYRNAPFKCSICYRGFMIKDRYDAHIIRHSEASGAYECFICKTRLKTGRALRKHLTAQHTEKFSCKGCPFVTRNRGVAREHEKWHAGAKYQCPHCPSEFDKLTTYMGHIRIKHVSDFVCELCGYTFVSKKGIDVHKKKKHRLVDKTVPLEGPYCEVCDVTFVSEEAHSRHLKLSSRHSSDNDPNRIRNDSQSMNAERHGRVVRRIERRPVIHPREPGDRERRPDPGGPVTCEQCGVQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGRIFQSMALLKDHMWVHTGEKRFKCDRCDKSFTQKTNLVFHMRVHSASRPSYECPLCGKHFAFYNNRRRHMFVSTFSRFDRDWPRRTLLPGP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00674354;
90% Identity: iTF_00994416;
80% Identity: iTF_00994416;