Mita017593.1
Basic Information
- Insect
- Metalampra italica
- Gene Symbol
- Zfa
- Assembly
- GCA_949699065.1
- Location
- OX452993.1:6303340-6312934[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0029 0.17 12.7 1.2 1 23 240 262 240 262 0.98 2 11 8.8e-06 0.0005 20.7 0.9 1 23 269 291 269 291 0.98 3 11 5.3 3e+02 2.5 0.9 1 21 295 315 295 318 0.81 4 11 1.7e-06 9.6e-05 22.9 1.7 1 23 325 348 325 348 0.93 5 11 0.0011 0.061 14.1 0.8 2 23 355 377 355 377 0.94 6 11 0.00012 0.0067 17.1 0.0 1 23 389 411 389 411 0.98 7 11 0.0023 0.13 13.0 1.0 1 22 417 438 417 442 0.91 8 11 0.00054 0.031 15.0 4.1 2 23 451 473 450 473 0.95 9 11 9.6e-05 0.0055 17.4 0.3 1 23 479 502 479 502 0.94 10 11 6.8e-06 0.00039 21.0 0.4 1 23 511 533 511 533 0.98 11 11 0.0033 0.19 12.6 0.2 1 23 539 562 539 562 0.96
Sequence Information
- Coding Sequence
- ATGGAAGAACCGCCTGGTTTAATTAAGTCCGTTTGTTACGGTTGCTTGTCTTTAAACgatgacatttttttacaaacgtATAATATACAGAATGAAGGACTAAAGGCAATGTTTCAGGTGGAGCATGTATGCCTCTGTTACTTGTGTAAGCGGAGAGCCCAGCAAGCCGAGCTGTTCATTCAGAATGTTCAAAGCAACCAGATTTTATTGGAAAATGttcataatCTGACAGAGTCAATGATATGTAAAGTGAGAACTCAAACCCAGGCGCTAACCAACCTTAGTCATTCACCCCAAGACTCGATAGAACTAGATGGTAAGGACGACTCGATCATAGAGGAGTCTTGCTTCGTTGTCTACAGCAGCTGTAACTTTAAAAGCGAAAAAGATTTCCGAATTAAACTTGAGGTGGAAACTGAGCATGGAATCACTGATAATTTTGAGGAGTTTACACATGATGACGATGATATTAAACCGTTAATAAAAGCAGAGGACGACGAAGACGATTATCCATTGAAATTGTTGAAGGAGTTACGATTAGAAGGCATTGACATTCAATGTTTAAGGAAACCAATGAAAAAAGGGaaagttaaaaagaaaaggaaaaatatagatttgaagcaagatttaaaaatagaaacaatGAATATAACTAGGCAGCAATGTATAGAAGAGAGAGCGATTGTAGcttcaaaaaaattgtatgtgGACTCGGCTTTTAAATGCGAGGATTGCATCAAAGGATTCAACTTTAAGGCGAGCTATGAAAAACATCTGGACAAACACAGTGAGAGGAACGGAGATTATGAGTGCAATATTTGTAAACAAAGATTTATATCGGAAGAGAAATTGACTGCCCATCAGAGATACCATTATGTGCGCTACAAATGCCGCGTGTGCAACCTAACACGCATCAGCCGCCTGACAATAAAGGACCACTACACCGCCTTCCACTGCAACGGGCACTACCCCTACCCCTGCCCGCACTGCCCCAAGGTTTTCAACCGCCAAGTGTCTCTCCGGAAGCAcaccgcgcacgcgcaccggcggcgcgagcgcgcgcgctgcgcccACTGCGACAAGTCTTACGCCACCAAGGAGATTCTCAAAGCGCACATGATCGAGCGGCACACCGAGGAGCTGGGCGTGACGAGGAGCAAGCGGTACGTGTGCCCGGTGTGCGGCGCCGCGTTCGGCGCGCCCTCGCAGCTGCGCAACCACGGCATGAAGCACTCGGACAGGCGGGACTACTACTGCGTCGAGTGCGACAAGAGCTTCAAGTCAGACGCTATACTGAAACACCATTTGAAGACCGCCATGTCACACACCAACTATTTTGACCTACCGCTGCACTGCCAACATTGCGACAAGCGTTTCGCCATCAAGCGAGATCTGGAGCGGCACACCAACCGCGTGCATCTCAACATCAAACCGTTCCTATGTGATAAGTGCGACAAGTCGTACGTGAACGCGTGGTCGCTCAACGACCACAAACGGCTGATCCACGAGGGGTACAAGCGGCCGCTGAGGTTCCCCTGCACCATGTGCGACAAAGTGTTCGACCGCAACCAAATACTAAAAGCTCACATCAGAACTCACACGGGGGAACGCCCGTACCAATGCAACAGATGCCCAGCCCAGTTCACCCAGGCCAGCATTTTGAGGACCCACGTGAAGCTGATACACTTGAAACTCACCAGAGATGGTAGACCGAAAGGTGGTAATGTCACTTTGAAGTGA
- Protein Sequence
- MEEPPGLIKSVCYGCLSLNDDIFLQTYNIQNEGLKAMFQVEHVCLCYLCKRRAQQAELFIQNVQSNQILLENVHNLTESMICKVRTQTQALTNLSHSPQDSIELDGKDDSIIEESCFVVYSSCNFKSEKDFRIKLEVETEHGITDNFEEFTHDDDDIKPLIKAEDDEDDYPLKLLKELRLEGIDIQCLRKPMKKGKVKKKRKNIDLKQDLKIETMNITRQQCIEERAIVASKKLYVDSAFKCEDCIKGFNFKASYEKHLDKHSERNGDYECNICKQRFISEEKLTAHQRYHYVRYKCRVCNLTRISRLTIKDHYTAFHCNGHYPYPCPHCPKVFNRQVSLRKHTAHAHRRRERARCAHCDKSYATKEILKAHMIERHTEELGVTRSKRYVCPVCGAAFGAPSQLRNHGMKHSDRRDYYCVECDKSFKSDAILKHHLKTAMSHTNYFDLPLHCQHCDKRFAIKRDLERHTNRVHLNIKPFLCDKCDKSYVNAWSLNDHKRLIHEGYKRPLRFPCTMCDKVFDRNQILKAHIRTHTGERPYQCNRCPAQFTQASILRTHVKLIHLKLTRDGRPKGGNVTLK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -