Mita014583.1
Basic Information
- Insect
- Metalampra italica
- Gene Symbol
- ZFX
- Assembly
- GCA_949699065.1
- Location
- OX452988.1:352264-356847[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 8.4 4.8e+02 1.9 4.9 1 23 265 287 265 287 0.97 2 15 2.5 1.5e+02 3.5 0.3 6 23 299 316 299 316 0.96 3 15 0.33 19 6.3 1.5 2 23 328 350 327 350 0.95 4 15 6.7e-06 0.00038 21.0 3.1 3 23 373 393 372 393 0.98 5 15 4.3e-05 0.0025 18.5 1.7 1 23 399 422 399 422 0.96 6 15 0.02 1.2 10.1 0.1 1 23 428 450 428 450 0.94 7 15 2.1e-05 0.0012 19.5 1.6 1 23 456 478 456 478 0.97 8 15 0.0064 0.37 11.7 1.1 1 17 484 500 484 500 0.96 9 15 0.026 1.5 9.7 2.3 1 23 644 666 644 666 0.95 10 15 0.00045 0.026 15.3 2.0 2 23 673 695 672 695 0.92 11 15 1.6e-06 9.2e-05 23.0 3.0 1 23 701 723 701 723 0.97 12 15 6.1e-07 3.5e-05 24.3 1.1 1 23 729 751 729 751 0.98 13 15 0.00022 0.012 16.3 1.0 1 23 757 779 757 779 0.98 14 15 0.0004 0.023 15.4 3.7 1 23 785 807 785 807 0.93 15 15 0.0011 0.065 14.0 0.6 3 23 815 836 813 836 0.96
Sequence Information
- Coding Sequence
- ATGAACAACGAAACAGAAGAAATATTTCTGCTGAACCCCACCGAAAGCCAGCCGTCCAGTTCAACACAGAAGATTTTTGAAGTGCCGACAATAGCACTTGAATTTAACCTCGAAAATGTTGACGACTTCACCAACGTTTGCCGGACGTGTGCCAGCATCACAGAGTTCCTCATCCCCATATTCGAGGGTGAAGGCTTGCACAACAATCTCGCTGAGAAGATACAGGAGCATTTACCCATACAGGTGACAGAGCAGGACGCGCTGCCCCGCGCGGTGTGCTACCAGTGCGCGCACACGCTGCTGGCGTGCAGCGAGCTGGCCgcgtgctgcgcgcgcgccgacgccgcgctgcgcgcgcgagcgcgcctcgccgccgccccccacgcgcccgcgcccccacCACTCACCGGACAACTAGAGGAACAAATGTCTACAGCAATCATGAAAGAAGATGCGAGTTTGAAACATGAACAACAGAAACAGTGTGGAACCCCAATGTTTGACAGAACTGTTAGAAATGTGTTACTTGGATACTTGTACACGATGAACAAACATGGAGACCATTCGGATCTGCAGTTTGTTTGCCAAAAGTGCGACGAGCATCCCGCCTCCACCACCATGGAGCACCTGACCGGACATTTGAAATGTGCACATCTCACGGACATGGAAACTAAACGCAGCATAGAGCAGTTTATAAGAGACTACGTCACTTTCGAGGAACCCCTGACATTGGAGGACTCTGATGGCGACGAGGAGGCGAACGGAGAGCCGCCCGGTGTGGTCCTGCAGAATTTCCGTTGCCTGTTTTGCCGCAGCGTGTTCTCTTCTAGCACCCGCCTCATGTGCCATCTCAACCGACACGTGGAGGTGTGCATCGACCGGGGCGTCGTGTGCTGCGACAACCGCTACGACGACAAGAACTCCTTCGTCTCTCACCTGCAGAAACATGTCGCTGGCGTGGCTGGCACCGGCGCGGGGACCACGTGCCGCAGCTGCGGGTTCGAGGCTGAGTCCAGAGACCATCTTCGGTCACACGTGACGACCAGTCACGACGCAGACGACGAAAGCGCAGCGAAACAACACCGTTCGAACGACCGGAAATACGCACCGGCCGCGTGTCCCGAGTGCAACAAACGGTTCTCCAACAAGTACCACATGCTGCAGCATCTGAGACGACACTCGGAGATAACGAAATACTTCTGCGACAGATGCGACCGGTCGTACACCACCCGCGGCAATCTGACCTACCATCAGAAACTAGTGCACGAAGGGGTGTTGAGGTTCCTTTGCAACTCGTGCGGCGAGGCGTTCCCGACGCGGCAGGCCCGCACCGTGCACGCACGCCTGCACACGGGTGAGAAGCCCTTCGCCTGCCATTACTGCTCGAGATCGTACCGCTCGAAGCCGACGCTCGAACGCCACATAGAGATACACTTAGATATTAGAAAGTATGAATGTCGCGTGTGTTCCAAGAGATTCCGCCGGAGCACCCACCTCAAGTGCGAGTATGCGCCGCACGATGCGCTCCGCCTCGCTAGCGCGGCCGACGAACGTGTCAAAATCGAAATCACTATCGATACCGATGATGGCGACGATTTCGAAGAAGCCGCTACGCCTCAATCCGACGACGATCTGCCCCTTTCCAATATGGCAACCATAAAATCGAACCGCCTGTACAACGATTTTTATACGGCGTTGATCAATTTTAGAAACCATTTTGTTTCTGAACACGAAACGGGAAACAGTTACCCGGATTTCACAGATTCCAGCGACTCGGAAATGGTACCGGAGGATGTCGGCGACGCTGGTGACGCGGCCGCTGACCGCTTCGACGATTTGACTCAGAGCAACATGAGAAAAGACAGGATGGACGACGAGACGAGATTGGAGCTCAACGAAGTCCAAACGAAAATCAACGGAAAAGTTTACTACTCGTGTAAGATTTGCGGGAAGAACCTGAGCTCGCCGCACACGTACGTGTTCCACAAGCGCATCCACACGGGGGAGCGGCCGTGCGTGTGCCACGTGTGCGGGAAGCAGTTCCGCGCGCCCAACGGCCTGCAGCGACACCTGACGGAGACCCACGACAAGGTCCGCCGACACTCGTGCCGGTACTGCCCCAAGAACTTCGCCAACTCGCAGAACTTGAAGCAGCACATGCGCATACACACGGGCGAGCGGCCCTTCGTGTGCTCCCAGTGCGGGAAGCGCTTCACCCAAAGCGGATCGCTGTACGTCCATTTGAAGACCCACAGCGAGCAGTTTCCGCACCAGTGCGCGGAGTGCGGGGCCAAGTTCCGACTGCGGTCGGGGCTGGCGAGGCACAGGCTGAAGCACACGGGCGAGCGGCCGCACGTGTGCGTCCACTGCGGGAAGGGGTTCCGGCAGAGGCACGAGCTGACCAGCCACGGCGTGTCGCACACCGACTCCAAGCCGTTCGGCTGCGCGGTGTGCGGCGCCGCCTTCAGACAACGCCGCGCGCTGAGGCACCACGCCAAGCGGCTGCACGAGGCCGACCGCCCGACGGCGCCCCGGGGCACCGATGTGTTGATCTATACGAACCTCGGACAGTATCAGTGA
- Protein Sequence
- MNNETEEIFLLNPTESQPSSSTQKIFEVPTIALEFNLENVDDFTNVCRTCASITEFLIPIFEGEGLHNNLAEKIQEHLPIQVTEQDALPRAVCYQCAHTLLACSELAACCARADAALRARARLAAAPHAPAPPPLTGQLEEQMSTAIMKEDASLKHEQQKQCGTPMFDRTVRNVLLGYLYTMNKHGDHSDLQFVCQKCDEHPASTTMEHLTGHLKCAHLTDMETKRSIEQFIRDYVTFEEPLTLEDSDGDEEANGEPPGVVLQNFRCLFCRSVFSSSTRLMCHLNRHVEVCIDRGVVCCDNRYDDKNSFVSHLQKHVAGVAGTGAGTTCRSCGFEAESRDHLRSHVTTSHDADDESAAKQHRSNDRKYAPAACPECNKRFSNKYHMLQHLRRHSEITKYFCDRCDRSYTTRGNLTYHQKLVHEGVLRFLCNSCGEAFPTRQARTVHARLHTGEKPFACHYCSRSYRSKPTLERHIEIHLDIRKYECRVCSKRFRRSTHLKCEYAPHDALRLASAADERVKIEITIDTDDGDDFEEAATPQSDDDLPLSNMATIKSNRLYNDFYTALINFRNHFVSEHETGNSYPDFTDSSDSEMVPEDVGDAGDAAADRFDDLTQSNMRKDRMDDETRLELNEVQTKINGKVYYSCKICGKNLSSPHTYVFHKRIHTGERPCVCHVCGKQFRAPNGLQRHLTETHDKVRRHSCRYCPKNFANSQNLKQHMRIHTGERPFVCSQCGKRFTQSGSLYVHLKTHSEQFPHQCAECGAKFRLRSGLARHRLKHTGERPHVCVHCGKGFRQRHELTSHGVSHTDSKPFGCAVCGAAFRQRRALRHHAKRLHEADRPTAPRGTDVLIYTNLGQYQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -