Mfus006067.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Mesopsocus fuscifrons
Gene Symbol
topi_1
Assembly
GCA_950004255.1
Location
OX465375.1:14410276-14415509[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 41 0.74 48 4.7 1.5 2 12 54 64 54 67 0.86
2 41 1.1e-05 0.00071 19.9 0.2 1 23 81 103 81 103 0.98
3 41 0.0011 0.072 13.6 2.8 1 23 109 131 109 131 0.98
4 41 0.0095 0.61 10.7 5.1 1 23 137 159 137 159 0.98
5 41 0.011 0.71 10.5 0.3 2 23 166 187 165 187 0.98
6 41 7.8e-06 0.0005 20.4 2.4 1 23 193 216 193 216 0.98
7 41 1.8e-05 0.0012 19.2 3.3 1 23 226 248 226 248 0.98
8 41 0.00012 0.0074 16.7 1.8 1 23 254 276 254 276 0.98
9 41 3.7e-06 0.00023 21.4 0.1 2 23 283 304 283 304 0.98
10 41 2.7e-07 1.7e-05 25.0 0.6 1 23 310 332 310 332 0.98
11 41 0.0014 0.09 13.3 0.6 3 23 340 360 338 360 0.97
12 41 2.8 1.8e+02 2.9 0.1 3 23 389 411 387 411 0.81
13 41 0.075 4.8 7.9 3.3 1 23 414 436 414 436 0.94
14 41 9.8e-07 6.3e-05 23.2 1.7 1 23 439 461 439 461 0.94
15 41 1.4e-05 0.00091 19.6 1.2 1 23 467 489 467 489 0.99
16 41 0.038 2.4 8.8 3.0 3 23 498 518 497 518 0.98
17 41 0.6 39 5.0 0.5 1 23 524 546 524 546 0.87
18 41 5.7e-05 0.0036 17.7 0.6 1 23 552 575 552 575 0.96
19 41 0.0025 0.16 12.5 0.6 1 23 582 604 582 604 0.96
20 41 0.017 1.1 9.9 3.2 3 23 612 632 610 632 0.95
21 41 0.0002 0.013 15.9 5.5 2 23 639 660 639 660 0.97
22 41 1.1e-07 7e-06 26.2 0.7 1 23 666 688 666 688 0.98
23 41 1.3e-05 0.00081 19.7 2.3 3 23 734 754 733 754 0.99
24 41 4.2e-06 0.00027 21.3 0.7 2 23 776 797 775 797 0.97
25 41 0.0035 0.22 12.1 3.8 3 23 806 826 804 826 0.96
26 41 0.0013 0.082 13.4 7.8 1 23 832 855 832 855 0.97
27 41 0.00077 0.05 14.1 2.0 1 23 861 883 861 883 0.97
28 41 5.2e-05 0.0033 17.8 2.7 1 23 889 911 889 912 0.94
29 41 7.8e-05 0.005 17.3 1.3 1 23 922 944 922 944 0.98
30 41 5.2e-05 0.0034 17.8 0.1 1 23 951 973 951 973 0.98
31 41 8.7e-06 0.00056 20.3 2.2 2 23 980 1001 979 1001 0.97
32 41 6.1e-05 0.0039 17.6 0.5 1 23 1010 1032 1010 1032 0.98
33 41 0.049 3.1 8.5 0.6 1 23 1133 1155 1133 1155 0.98
34 41 1.4e-05 0.00091 19.6 1.6 1 23 1220 1243 1220 1243 0.97
35 41 2.1e-05 0.0013 19.1 0.3 2 23 1250 1271 1249 1271 0.97
36 41 0.0041 0.26 11.8 6.4 1 23 1277 1300 1277 1300 0.97
37 41 0.0012 0.079 13.5 0.2 1 23 1308 1330 1308 1330 0.97
38 41 0.0015 0.097 13.2 0.7 1 23 1336 1358 1336 1358 0.94
39 41 8.1e-05 0.0052 17.2 0.2 2 23 1369 1390 1369 1390 0.97
40 41 0.00046 0.029 14.8 4.8 3 23 1398 1418 1397 1419 0.96
41 41 0.096 6.2 7.5 3.2 2 21 1438 1457 1438 1458 0.94

Sequence Information

Coding Sequence
ATGGATGAAGAGTTCATACCGAAGACGGAACGACGACGCCTCACAGGCCCTATCAGATGTGACAAGTGCCGACTCGTGACGTCTCGCTATAAACGACAGAAAGGCAAGAGGTTGTGCTTAGATTGCGCCGGGTCGGGTGGACAAGTACTTGGCCGAGCAAAATGTAAGCAGTGCGGTAAAAACTTTCGGGTCCATAAGTCAAGATCAGCGTGTTGTGCCGTTTGCACCACGAGCACGGAATATAAGTGCAGCATTTGCAGTGAAGTTTTCAGCGTAGCAGCGCACCTCGAGCGCCATGTACTGGTCCACCCAGACACCAAACCCTACTCGTGTCGTGTGTGCAACAAGAAATTCAAGCGGCTCATGTCCATGACGGTGCACGAAAAAAAACACTCGGGCAATCTCAAGTATGCTTGCAACGTTTGTTCCTACAAGTGCGCTCACAAGTCTTCCCTAGAGCTACATAAAAAGAGGCATAGTAAAGAGTATAAAGTTAAGTGTGAAACGTGTGCAAAAGGGTTTTACTCGATGAATGAGCTACTGGACCACTACAACACTCATACTGGTGCGCGCCCTTACAAATGTGATGAGTGTGATAAAGCCTACCCATACCGACACAATCTCACAGCTCACAAAAAAACGCAGCACTTGGCAGCATCTCAGGAGCGGAAGATGCACCAGTGCCAGGAATGTGGGAAGGTTTTCGCATTTAAAAAGTCTCTTACTTTACATAGAAAGTCGCACACGGGTGAAAATGTGTTTGTATGTGATATTTGTGGCAAGACGCTGACCAACAAAGATCACCTCATGTTCCATAGAAGGATTCATACGGGTGAAAAACCGGCGACGTGCGATATTTGTGGCAAAGGCTTTGCGAAGCCAGGTAATTTGACCCTTCATCGTCGCGttcatactggggagaaacccTACGCCTGCGAAATGTGCGgcaagagcttttctcagcgATCAACACTTGTAATTCATCAGAGATACCATACGGGCCAGCGACCCTACGGCTGCGACATGTGCGGCAAGGCGTTCGTCTGCCAGGCTCTTCTCACAGCACACACGCGCTCGCACCGCAACATACCCTTTGAAAATAGCCTtcttgttttCCGCACGAAGAGAAAGGTGGAAATTCAGTGCGATGTAAAGCCGTACTTGTGCAGCGTAGATTCTTGTTTCTTTGCTGCCGCAACTCCGGGTGACCTCAAGCGTCATGGAAAATCACATGCCGGCTACAAGTGTCGAGTGTGTGCCGAACGCTTCGAAAAGCGCGTCCAATTGCGCAAACACTGCGAGACCCATGCGAACTTCACCTGTGAGGTGTGCGGCAAGAGTTTTGGTAGACAGAGCCATCTTAAGCGTCACTCTGTCGTACATATTCCGGAACGTGCCTATGTCTGTTCGTTTTGCAACAAGGCTTACAAGACTCTGGCTACACTGGAGTCACATCAACGTCGCCATGAAAATCCCGATGACCTTTTGCTCTGTgagttttgtaattttactaCAAAACATCCCTCCACATTTAGTGTCCACGTGAGACGTCATACCCGCAACTACCCCTTTACCTGCGACACCTGTCAGAAGGGTTTCTTTGTTCGGAGTATTTACCTTGAACATGCGAATATTCACGCGGGTCTCAAACCCTTCCAGTGTGACGAATGTGGCAAGGCGTTTGCTTTCACACGCTACCTCAAAGACCACAAGCGCGAGGCGCATGGGATAACCAAGCCCCTGTTCAAGTGCCGCACGTGCCAGGCGCAATTCCCGGTACGCAGCCAGCTTCGCAAACACTGGGTTGTTCATACGGGAGAACGGGTTCATCTGTGCGACGTTTGTGGCAAAGGTCTCTCAAGTAAGGAACACTTAAAATTTCATCGAAGGATCCATACAGGTGAGAAGCCCAACGTGTGCCACGTTTGTGGCAAAGGTTTTGCTAAGAAGTGCAACCTCATCCTTCATCATCGCACGCATACAGGGGAGCGGCCCTACATTTGCAAAATATGTGACAAAGCGTTTTCTCAACGATCTACACTAGTTACCCACATGCGTCTTCACTCGGGTGAGAAGCCGGGCAACAAGGAAAATGAGGGCGGTGGTACTTACTTGTGCAAGACATGTGGAGAGCAAATGTCTATGGACCGTGCAGAGACGCACAATTTTTTAGCTCATCCCGAAGCCAGCTTACAGCTCTGTTCCGTCTGCAACAAAATGTTTTGCACACGAGATGACCTTCTCATTCACATGCGATCGCATCCGAAACCACCCAAGTCCAAAAAGGGCCAGCGTGGTTGCGGTGAGAGTCATTCTGCCGAATGGCGGTGTGACGTTTGCAATAAAACGTATCCCACGAATCAGCAACTCAAATCCCACATGAAGGTGCACAAACATGAACCTTATTCGCTTGACTGCAAAATCTGCCACAAGGTTTTCAAATCAACACATTATGCCCGTGAGCACCTGAAGGTGCACACAGGTGAGCGCCCATTCAAGTGCCACCTTTGCAACCGGAGCTTCATGCAAAAGCAGCACTTGATTAGTCACAAAAAGAGGCAACACTTCAAGCAACACGCATTTCGATGTGACCTGTGTGAAAAAGGCTTTCATTCCAAAACAGAGTTGCAAGTTCACAAAAATTGGCACAACGGCGAGCGGCCCCACGCCTGCGATGTCTGTGGAAAATCATACCCAAGTAAGTCCAACATGATGGGGCATAAGCGGACGCACCACCCCAAGCCAGATGGATCCCTCACGCGCTACCCCTGCCCCAACTGCCAGCGTCAATTTATGACCAAACGCTCGTTACTCAACCACTTGCGACAACACACGGGGGAGTCTGGCCAGTTTCCATGTGATTTGTGTGGGAAGGCGCTTAGTAGCCGGCAGTCACTCAAGGCTCATCGCATGATTCACACGGGTGAAAAGCCGATTACGTGTTCACTGTGTTTCAAGGCTTTCACAACAAACAAGTATTTGAGAACACACATGCGGTCCCATGGAAGTCATGATATTGGCAAACTGTTTAAGTGTGATGCATGCGGACAAACATTCACTCAGCGGGGTCAGATGGAGGCCCATAAGTTAACACACGATTGTACCGTTCAACTCGTGGTGCATGAACCAATggaacagcagcagcagcaacatcAGCAAGAACATCAGCCTCACCAGCAGCAGCATCCCCTCGTACAGCAGCACGTTGTTGTTCATCAACGCACACAAACGGACCATCCCGCTATGATTGTCACGCAACAGGCGTCCATGCTTGTGACGCACCATCGCCTACAAACCGATGGGCAAACGACCCTGTTGGTTGCCCGCCCGCCCGAACAGCCTATGCTCGTCACCCAGCGTGTTCAAACAGAGCCTTGTCTCGAGCCAGAGGCACCCTTCCAGTGCAGTCTGTGTCGAGTAGAGTGTGGTTCCAAAGCTGTCCTCAAAGCTCACCAGGCCACACACAACTACTCTTACCCAATGTTTACACTTATCCTTAATCCAGAAGACATAATTGATGTGGAATTGGAAAGCAGCGGCTCTGAGTTAGCGCATGACGAAATAGAGAGTCAGCTGAAAGTGAGAGAAAGGACCAAAGCTTTGGACAAGCTGTCTCAGTTGTCAGTAGCAATTGACGTCGCTAAGAAACCACAGCCTTTTTCCTGCAACCTTTGTCCGAAGGGGTTCACTGTGAAACACAGTTTAGAAAAACACGTGAGACGCGTCCATACCAAGGAGTACTTGCTGTACTGTAAAGTCTGCAAAAAGGGCTTCATTGTGGCCGCAGAGCTTCGGCGCCACATGAACAAACACACAGGCAATCAGCCTTATGTTTGCAACCATTGcggtagaaaatattttactcaCTCGTCACTTTCCTACCATAAGCGCTATGTTCACCGAATGGATGACGACCCTAGCTTTGACTGCGAACTCTGCGGGCTTAAATTCCCCTATGCCAACCGCCTCAAAAAACACCTTGAAGTACATGCAGACTTACGCGCCTTTCTATGTGATTTGTGTGGAAGGGCTTTTTTGAGGTCTACCGAGTTGAAAAGGCACCGTGATTCTCACGAACCAGGCTTTAAAAATACTCTGAAGAGAGTGTGTGAAGTGTGTGGCAGTAGCTACGCTTCTTCTAAATCGTTGAAAGTGCACATGCGGCTTCACACTGGCGAGAAACCTGTACTGTGCACCACGTGTGGCAAGCGCTTCGCCCAACATACATCGCTCTATTCCCACGTCCGAACTCATCATAAGGAGCAGAAAAATGACGTTTCCAACTGGAAAGTTGGGAAAATAAGGATAAACACATGCAGCTTATGTGGGCTGTGTTGCAACTCTTCCAAAGAGTATGAAAAACACTTGAATGACCGTGCTTGTCAGTAG
Protein Sequence
MDEEFIPKTERRRLTGPIRCDKCRLVTSRYKRQKGKRLCLDCAGSGGQVLGRAKCKQCGKNFRVHKSRSACCAVCTTSTEYKCSICSEVFSVAAHLERHVLVHPDTKPYSCRVCNKKFKRLMSMTVHEKKHSGNLKYACNVCSYKCAHKSSLELHKKRHSKEYKVKCETCAKGFYSMNELLDHYNTHTGARPYKCDECDKAYPYRHNLTAHKKTQHLAASQERKMHQCQECGKVFAFKKSLTLHRKSHTGENVFVCDICGKTLTNKDHLMFHRRIHTGEKPATCDICGKGFAKPGNLTLHRRVHTGEKPYACEMCGKSFSQRSTLVIHQRYHTGQRPYGCDMCGKAFVCQALLTAHTRSHRNIPFENSLLVFRTKRKVEIQCDVKPYLCSVDSCFFAAATPGDLKRHGKSHAGYKCRVCAERFEKRVQLRKHCETHANFTCEVCGKSFGRQSHLKRHSVVHIPERAYVCSFCNKAYKTLATLESHQRRHENPDDLLLCEFCNFTTKHPSTFSVHVRRHTRNYPFTCDTCQKGFFVRSIYLEHANIHAGLKPFQCDECGKAFAFTRYLKDHKREAHGITKPLFKCRTCQAQFPVRSQLRKHWVVHTGERVHLCDVCGKGLSSKEHLKFHRRIHTGEKPNVCHVCGKGFAKKCNLILHHRTHTGERPYICKICDKAFSQRSTLVTHMRLHSGEKPGNKENEGGGTYLCKTCGEQMSMDRAETHNFLAHPEASLQLCSVCNKMFCTRDDLLIHMRSHPKPPKSKKGQRGCGESHSAEWRCDVCNKTYPTNQQLKSHMKVHKHEPYSLDCKICHKVFKSTHYAREHLKVHTGERPFKCHLCNRSFMQKQHLISHKKRQHFKQHAFRCDLCEKGFHSKTELQVHKNWHNGERPHACDVCGKSYPSKSNMMGHKRTHHPKPDGSLTRYPCPNCQRQFMTKRSLLNHLRQHTGESGQFPCDLCGKALSSRQSLKAHRMIHTGEKPITCSLCFKAFTTNKYLRTHMRSHGSHDIGKLFKCDACGQTFTQRGQMEAHKLTHDCTVQLVVHEPMEQQQQQHQQEHQPHQQQHPLVQQHVVVHQRTQTDHPAMIVTQQASMLVTHHRLQTDGQTTLLVARPPEQPMLVTQRVQTEPCLEPEAPFQCSLCRVECGSKAVLKAHQATHNYSYPMFTLILNPEDIIDVELESSGSELAHDEIESQLKVRERTKALDKLSQLSVAIDVAKKPQPFSCNLCPKGFTVKHSLEKHVRRVHTKEYLLYCKVCKKGFIVAAELRRHMNKHTGNQPYVCNHCGRKYFTHSSLSYHKRYVHRMDDDPSFDCELCGLKFPYANRLKKHLEVHADLRAFLCDLCGRAFLRSTELKRHRDSHEPGFKNTLKRVCEVCGSSYASSKSLKVHMRLHTGEKPVLCTTCGKRFAQHTSLYSHVRTHHKEQKNDVSNWKVGKIRINTCSLCGLCCNSSKEYEKHLNDRACQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-