Mfus006073.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Mesopsocus fuscifrons
Gene Symbol
ZNF296_1
Assembly
GCA_950004255.1
Location
OX465375.1:14435359-14443582[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 46 3.2e-06 0.0002 21.6 1.0 2 23 116 137 115 137 0.97
2 46 0.14 8.8 7.0 0.8 1 23 143 165 143 165 0.97
3 46 1.2e-05 0.00078 19.8 1.6 2 23 172 193 171 193 0.96
4 46 6.1 3.9e+02 1.9 3.7 2 23 200 221 199 221 0.96
5 46 2.6e-05 0.0016 18.8 1.6 1 23 227 249 227 249 0.95
6 46 0.0041 0.26 11.9 0.4 1 23 255 278 255 278 0.93
7 46 0.12 7.9 7.2 0.1 2 23 289 311 288 311 0.88
8 46 4.7e-05 0.003 17.9 1.0 1 23 317 339 317 339 0.98
9 46 0.0056 0.36 11.4 0.6 3 23 347 367 345 367 0.97
10 46 3e-07 1.9e-05 24.9 1.1 1 23 373 395 373 395 0.99
11 46 0.28 18 6.1 4.3 1 23 453 475 453 475 0.97
12 46 0.0088 0.56 10.8 0.0 1 23 481 503 481 503 0.95
13 46 2.8e-05 0.0018 18.6 0.4 1 23 509 531 509 531 0.94
14 46 0.38 24 5.7 2.5 2 23 538 559 537 559 0.96
15 46 0.0013 0.086 13.4 4.7 1 23 565 587 565 587 0.97
16 46 0.00033 0.021 15.3 2.2 1 23 593 616 593 616 0.97
17 46 0.088 5.7 7.6 0.0 2 23 655 676 654 676 0.97
18 46 0.0012 0.074 13.6 0.1 1 22 682 703 682 706 0.91
19 46 0.012 0.79 10.3 3.7 2 21 710 729 709 730 0.93
20 46 0.00041 0.027 15.0 0.0 2 23 766 787 765 787 0.95
21 46 0.0004 0.026 15.0 1.5 1 23 793 815 793 815 0.98
22 46 0.0042 0.27 11.8 0.1 1 23 821 843 821 843 0.95
23 46 0.025 1.6 9.4 0.9 1 23 849 871 849 872 0.95
24 46 0.00011 0.007 16.8 0.9 1 23 878 900 878 900 0.97
25 46 2.6e-06 0.00017 21.9 0.2 1 23 909 931 909 931 0.97
26 46 0.0026 0.17 12.5 1.2 1 23 938 960 938 960 0.97
27 46 0.00011 0.007 16.8 0.4 2 23 967 988 966 988 0.95
28 46 4.8e-05 0.0031 17.9 0.2 2 23 994 1016 993 1016 0.96
29 46 0.0028 0.18 12.4 1.0 2 23 1050 1072 1050 1072 0.97
30 46 0.0026 0.16 12.5 2.9 3 23 1080 1101 1078 1101 0.93
31 46 0.032 2.1 9.0 3.9 1 23 1105 1127 1105 1127 0.93
32 46 0.0007 0.045 14.3 2.8 2 23 1142 1164 1141 1164 0.95
33 46 3.6e-05 0.0023 18.3 0.4 1 23 1170 1192 1170 1192 0.98
34 46 7.5e-07 4.8e-05 23.6 0.2 3 23 1199 1219 1198 1219 0.99
35 46 0.0011 0.069 13.7 2.3 1 23 1225 1248 1225 1248 0.97
36 46 2.4 1.6e+02 3.1 0.0 2 20 1324 1341 1323 1343 0.90
37 46 0.11 7 7.4 1.1 3 23 1353 1374 1351 1374 0.91
38 46 0.17 11 6.8 4.1 1 22 1377 1398 1377 1400 0.89
39 46 0.1 6.6 7.4 0.1 2 22 1409 1429 1408 1431 0.85
40 46 0.00017 0.011 16.2 0.9 2 23 1440 1461 1440 1461 0.97
41 46 0.04 2.6 8.7 0.2 1 23 1467 1490 1467 1490 0.91
42 46 9e-07 5.7e-05 23.4 3.5 1 23 1494 1516 1494 1516 0.99
43 46 2.6e-05 0.0017 18.8 5.1 2 23 1528 1549 1527 1549 0.97
44 46 0.00022 0.014 15.9 0.1 1 23 1556 1578 1556 1578 0.97
45 46 6.7e-06 0.00043 20.6 0.5 3 23 1586 1606 1584 1606 0.97
46 46 3.9e-05 0.0025 18.2 4.9 1 23 1612 1634 1612 1634 0.98

Sequence Information

Coding Sequence
ATGGAGTTGCCCAAAAACGTAGTACATGCACTGTGTGTGGCTTTGTGTGCTCAGACCGAGATGTGTTTACAACTCATCAACGTAGCCACCGCGTTCGATGCCCCAAGTGTGAGCGCAAGTTTAAATCGACTTCAGAAATGTCGCGCCACCTTGAAATGCACGCTGAACCTCTGCTATGTCACATTTCATCATCCTTACCGAGGCAATCGAGCCAAACGCAAgagagaaattgaaaattgcatTATTAAAGTATTTGAAGCGAAAATTGCAGAAACAAGTttcataaaaatggaaaatggtgAGAAAAAGTGTGAGAAGAGACAACCCAAAGACAAGCGAGATATCAGCTGCGAGTTTTgtggaaaaatattcaaaCGAAAAGGGAATTACGAAGAACACCGGCGCACGCACACCGGAGAGAGGCCGTTCGAGTGCGGGTTCTGCCTGATGCGCTTTGGTTCCCATGCAGGCCTCAGTCGACATAAGCTCGTACACCAGGAACAACGCCCCCTACCCTGTGACGTCTGTGGTAAAACCTTTAAGCACCAAGTCCAGCTCAGATATCACAAAGAAACTCACAGCAACACAACTCCCTTGCAGTGCGACCTGTGCAGTTACACCTCCCTATCGAAACATTACTTGAATCTTCACCACGCCACACACCTCAATCGTGATCGTTTCCTGTGTAGTATTTGCAACAAACGCTTCAATTCCCGAACTTACCTCGCCGAGCATATGAACAAACACTCTGGCCTGAAGCCGTTTCTCTGTGATATCTGTGGCAAGGCTTATCCGGCTCGTTACAGCCTTGCTGCTCATAAACATATGAAACACGATCCCAACTATAAACCGAGAGACCGTATACCATGTCCCTACTGTGGCAAGATGGTGCTCAATCGGAAACAAGATTTGGTGCGACATCGGGGCATTCACACTGGTGAAAAACCATTTGTGTGCCATTTTTGTGGTAAGGGAGTCACAAATCGTGAGTCGCTAAAAATTCACGTCCGCCTGCATACTGGAGAGAAGCCGTTTGGTTGTGACGCATGTGGCGTTCACTTTGTGAGCCGCAACTTGTTACGCGTGCATCGGCGAATTCATACAGGGGAGAAACCGTATCGATGTGACTTGTGTGATAAGACGTTCACACAGCGCTCCAGTCTGGTGGTGCATCGACGCATACACAGTCACTCCACAGAAAACGTCCCTGCCCAGCCTACGCTTGATTGCTCCGATGCGTTCACTCTGGAAGACCAGAAGTCCCACTCTATATTCGTGTATGACGTGCTAGGTGCATGTGAATCCAGTCGGGAAGTTGTCGAGTTGAACATAAAAATCATCAATGCGAGTGGAGTGCACACGTGCGAGTTTTGTCGCAAAGGTTTTAAATGGCGTAGTGCCTTGCTTCAACACCGCCACGTGCATACCAAGGAAAAGCCTCATGCTTGTGAGACGTGCGGTGCAGCATTTGGCTCCTACGCTGGTCTCTGGAAGCATCGTGCTGTGCACAACCAAGACAAACCGTTCGTCTGCGAAACCTGTGGCAAGGTCTTTAAACGCGCCGTACAGTTGAAGTATCATAGCGAATTGCATACTGGGACAGAGCTCCTCTCGTGCCTTCAATGCTCCTACACTACAGTGTCACGTCGATGCCTGCAGCTCCACTTGGACACCCACCGTGCCAAGCTCAAGCATGTTTGCCGAGTCTGTGGCAAATGTTTCAACGCAAAATCCTTCTTgtttgaacatttaaatcgGCATACGGGGGAGCGGCCCTTTCAGTGCGAGGATTGTGGGAAAACTTACCACGCACGGAGCAGCTTGATGGTACACAAACAAAGTAAGCATCGGATGTCGACACATGACCTCTGTGCAATTTGTGGCCGTTCGGTTGGGGGCGGGAAGCGTGGGATGCAGCGGCATATGCACACTCACTCCGTGGCCTCTGTTGTCGGGGCCGTAACATGCGCTGAGTGTGGTGTATTGCTCAGTTCTGAGGCAGAATTAGCGGTCCACCAGCGCCTGCATTCGGGAGAGTGTCCATTTGTGTGCAATTCTTGTCCCGAAGCGTTTATTAGTGAAAGCTTGTTAAGGGCACATAAACGTGCGGCTCGACATCAACCACTCAAATGCAATCGCTGTGGTTGTTGCTTTAAGAAGCAGTCAAGACTGGCAGTTCATCTTGAAACTTGCATCAAGGAAGCATTATTGGCTGAAACTGGCTTTTTACTGGAAGAGGGCTTTGTTGTGCTGGCACCTGGCACGCCTTGTTCGTTGGAGAAAACTCAAGAATGGATTTGTGGAGAGTGTGGGAGACCATTTCAGAAGGCCAGCTCGTTGGCGCGCCACGTAGCTGTTCACTCCAATGACCGACCTTACGCATGTGTCAAATGTGAGCGAAGATTCAAGCGAGAGCAGGACATGCGTGCACACACTCGGCGCCATGACAGTGCTCCACCTTTTGCATGTCCCAGCTGCCCTGCGACATTCTACCGCGCGTCACGCCTCCGCGTTCATGAAGACCGACACCTGGCTCGCTTTCGGTACTCTTGCGGTACCTGTCGGGCTGGATTCCCCACATCGGGAGAGTTGCATGTGCACTCTGCTACCCATCATGATGCTCGCGTACCCCACCCCTGCCCAGAGTGTCCTCGTATTCTCCCCCACAGCTACGGACTGCAAAAACATTTGAAAACCCATGACCTTGATTTTATCCCCAAACACTACGCTTGCGAGGTCTGTGGAAAAGTTTACAGTAGTAAATCAGCGCTTAAAGTTCACACAAGTTCCCATTCGGATGTTGATCGCACGTACATATGTCATATGTGTGGGAGCCAGCTCCGTAATAAAGCATCGCTGACTTCACACTTGCAGTTACACTCGGCGACCAGAATCTGGACATGTGACCCTTGTGGCAAAAACTTTGCCCGTAAAAAAAGTCTTCAAGTCCACCTTTCTACCCATGGTGGGGTGAAGCTGACTTGTGAAGAATGTGGTAAAGTGTTCAAGACAGAGAATGGTATGGATGAGCACATGCGTCGTGTACATGGGCCAGTCGTGCTGGAGACGTGTTCCGTGTGCAGTAACGCTGTAGCGATGTGGCGAATGAAAAACCATATGAAAAAACATGATGACCAAGCTCAGGAAAAGTGTCTACAGTGTGACTATGTCACGTACAATAAGTACTACTTGAAGGAACACGTCCGACGAATGCATGAAGTTAATCCTGACTGGATTTGTGCTTTGTGTGGTCGCAAATTCTACCGAAACTGTCACCTACAAGAGCATTTGCAGGGGAAGCATGGCGATGGGTACCAGTGCCGGATATGCCGAGAAACTTTTCACAACAAGACGTACTGGAAGCGCCACGAGTTTGCCCACTACAAGCCGAGACAGCCTGCGCCTCCTCGAGCCAAGGATTGGCAGTGTCAGCACTGTGGCAAGACTTACACTAGTCGAATTTTGATGAAGGACCATATTAATCATGTTCACGGACCAAGAGTGGATTATCCTTGTAAATCATgtccaaaagttttttcttctattcGATCCCTAAGGGCCCACACGAAAATTCATGGGGAAAGGTCGCGATTATGTCCAGTTTGTGGAAAAGGATTTACTGTACAGAGAAATCTGTCTGTGCACATGAGAACTCACAGTGGTGAGCGGCCTTATCCTTGTACGCTCTGCACTAGTGCTTTTACGCAGCAGTCTGCAGTTCAGAGGCATCTCAAAAAATGCCATGGTGTCGAAAAGTGTCTCGAGACGGAGCCCGGAGTGGATACCCGACTGCGACAAAAAAGTCTACTTGTAGCGCGGAATCACAGACTGAAAAAGTGTCGCAAGGTTTTACGACCGACGTCGGGCGACGATACGAAAAGTGACTTGGAAGCTTACCTACGGGCTTACTTTGAGCCCGAAATCAAGATTGAGGCTGAGCAGGCAGCTGAACCCGCACCCAGTCATGTGCGGTGCACTCTGTGCGGTGAGATGATACCTCTTTCGAACCTCAATAAACACAAGCTTATTGAGGAAAACTACCTTGCGTCGCAACACTGCGTCCTCTGTAAcattgatttcaataaaaaatcagcCTTCCGCATTCACATTTATGAGCAACATAAAATATACCATTGCAAGACGTGCTCGCAGGTATTCAAAAAGCGGCAGCTGTACCGTAACCATAACGAACTGATGCACGGTGTGAAAGCGAAAGTTCGCGTACCCTGTGAGCTTTGCGGTCGGTTCTTTGCGAATAAAAAGATAATGAAGAGGCATGCAGCCGAAGTGCATTTTGGACATCGTGAACCTGAGGCCAAGTGCCCGCAGTGTGATTACCGTTCCTATAATCGCTCCAATCTCAAGGTTCATATAGACAAGCACAACAATACACCAGCGTTTGTCTGTGACCTCTGCGGTATGGGCTGCTTCACAAAGACTGCGCTCAACGATCATGCTGCGAACGCGCATGGCCACGGCTTCAAGTGCCCGACTTGTGGTAAATGCTATCGAAATGACAGCAGTCTCAAGTCACACATGAAGGTGCATGAGCCAGGCTTCGATCCTGCGACGGTGCGTCAACAGTGTGAGCACTGTGGCGAATTCTTTAACCACAAAAGTTCCCTTAACAAACACTTACTGCGACATTTGGGTCTTGGCAAAACGTTTGACTGTGATGTTTGTGGCAAGAAAGTGGCTTCAAAGGGTTCATACCGCTCCCACATGGCCATCCACTCGGGCTACAAGCCGTGGGCCTGTGAGTACTGCGACAAACGCTTTGCTGATCGTCAGTACCTTACGCAGCACCGCCGCATCCACACTGGGGAAAAGCCCTTCAAGTGTGACGCCTGCGGTCAGTGTTTCAACCAGCGATCTTCCCTCACCCGCCATAAGCGCTACCACACCTCTGGGCGGGTGGCTCGCTAA
Protein Sequence
MELPKNVVHALCVALCAQTEMCLQLINVATAFDAPSVSASLNRLQKCRATLKCTLNLCYVTFHHPYRGNRAKRKREIENCIIKVFEAKIAETSFIKMENGEKKCEKRQPKDKRDISCEFCGKIFKRKGNYEEHRRTHTGERPFECGFCLMRFGSHAGLSRHKLVHQEQRPLPCDVCGKTFKHQVQLRYHKETHSNTTPLQCDLCSYTSLSKHYLNLHHATHLNRDRFLCSICNKRFNSRTYLAEHMNKHSGLKPFLCDICGKAYPARYSLAAHKHMKHDPNYKPRDRIPCPYCGKMVLNRKQDLVRHRGIHTGEKPFVCHFCGKGVTNRESLKIHVRLHTGEKPFGCDACGVHFVSRNLLRVHRRIHTGEKPYRCDLCDKTFTQRSSLVVHRRIHSHSTENVPAQPTLDCSDAFTLEDQKSHSIFVYDVLGACESSREVVELNIKIINASGVHTCEFCRKGFKWRSALLQHRHVHTKEKPHACETCGAAFGSYAGLWKHRAVHNQDKPFVCETCGKVFKRAVQLKYHSELHTGTELLSCLQCSYTTVSRRCLQLHLDTHRAKLKHVCRVCGKCFNAKSFLFEHLNRHTGERPFQCEDCGKTYHARSSLMVHKQSKHRMSTHDLCAICGRSVGGGKRGMQRHMHTHSVASVVGAVTCAECGVLLSSEAELAVHQRLHSGECPFVCNSCPEAFISESLLRAHKRAARHQPLKCNRCGCCFKKQSRLAVHLETCIKEALLAETGFLLEEGFVVLAPGTPCSLEKTQEWICGECGRPFQKASSLARHVAVHSNDRPYACVKCERRFKREQDMRAHTRRHDSAPPFACPSCPATFYRASRLRVHEDRHLARFRYSCGTCRAGFPTSGELHVHSATHHDARVPHPCPECPRILPHSYGLQKHLKTHDLDFIPKHYACEVCGKVYSSKSALKVHTSSHSDVDRTYICHMCGSQLRNKASLTSHLQLHSATRIWTCDPCGKNFARKKSLQVHLSTHGGVKLTCEECGKVFKTENGMDEHMRRVHGPVVLETCSVCSNAVAMWRMKNHMKKHDDQAQEKCLQCDYVTYNKYYLKEHVRRMHEVNPDWICALCGRKFYRNCHLQEHLQGKHGDGYQCRICRETFHNKTYWKRHEFAHYKPRQPAPPRAKDWQCQHCGKTYTSRILMKDHINHVHGPRVDYPCKSCPKVFSSIRSLRAHTKIHGERSRLCPVCGKGFTVQRNLSVHMRTHSGERPYPCTLCTSAFTQQSAVQRHLKKCHGVEKCLETEPGVDTRLRQKSLLVARNHRLKKCRKVLRPTSGDDTKSDLEAYLRAYFEPEIKIEAEQAAEPAPSHVRCTLCGEMIPLSNLNKHKLIEENYLASQHCVLCNIDFNKKSAFRIHIYEQHKIYHCKTCSQVFKKRQLYRNHNELMHGVKAKVRVPCELCGRFFANKKIMKRHAAEVHFGHREPEAKCPQCDYRSYNRSNLKVHIDKHNNTPAFVCDLCGMGCFTKTALNDHAANAHGHGFKCPTCGKCYRNDSSLKSHMKVHEPGFDPATVRQQCEHCGEFFNHKSSLNKHLLRHLGLGKTFDCDVCGKKVASKGSYRSHMAIHSGYKPWACEYCDKRFADRQYLTQHRRIHTGEKPFKCDACGQCFNQRSSLTRHKRYHTSGRVAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-