Mwes010970.1
Basic Information
- Insect
- Merzomyia westermanni
- Gene Symbol
- -
- Assembly
- GCA_949987695.1
- Location
- OX465289.1:26384319-26389583[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.46 76 5.7 5.7 2 23 181 203 181 204 0.94 2 18 0.67 1.1e+02 5.1 3.4 2 23 252 274 251 274 0.94 3 18 0.00011 0.018 17.1 0.2 2 23 289 311 288 311 0.93 4 18 0.0063 1 11.5 0.1 1 20 321 340 321 342 0.92 5 18 2.6 4.4e+02 3.3 0.1 2 12 372 382 371 386 0.90 6 18 0.00019 0.032 16.3 2.4 1 21 409 429 409 430 0.96 7 18 4.4 7.3e+02 2.6 3.1 1 23 476 499 476 499 0.86 8 18 4.1 6.7e+02 2.7 0.2 1 11 551 561 551 564 0.91 9 18 1.8e-06 0.0003 22.7 1.0 3 23 598 619 597 619 0.96 10 18 0.24 40 6.5 3.9 1 23 673 695 673 695 0.97 11 18 0.63 1e+02 5.2 3.7 3 23 728 749 727 749 0.90 12 18 1.6 2.7e+02 3.9 0.6 3 20 802 819 801 821 0.93 13 18 9.6 1.6e+03 1.5 3.4 1 23 1106 1129 1106 1129 0.87 14 18 0.0022 0.37 12.9 0.2 1 23 1203 1226 1203 1226 0.95 15 18 3.9 6.4e+02 2.7 2.7 1 23 1273 1296 1273 1296 0.96 16 18 4.7 7.9e+02 2.5 0.6 1 23 1302 1325 1302 1325 0.95 17 18 0.87 1.4e+02 4.8 0.9 3 23 1335 1355 1334 1355 0.96 18 18 0.00062 0.1 14.7 3.4 1 23 1362 1385 1362 1385 0.98
Sequence Information
- Coding Sequence
- ATGGCGGATTCATCTATGTCCGAAGAAGAGTCACCATATGAAGAAGATACTGACatcgaaaatacaaaagttttaaagtcTCAAGCTGTgttgattgaaaatgaaaattatgctGACTCTAATACTGATTCTGAAGACGGTGAACCGTTGGCAAATTTGAAACCTAAAATAACATTAATGGAAAATGATAACAATAACAAGTCTAGTGCTGATAGTGAGGAAGAtggacaaagaaaaaaatccaaCCTTAATTACAACGCAGCGGAAGTTGACGACGATGATGCTTCTAATTCTAGTACTGAAGAGGATGAACCAATGATAAATATAAACCTTAAAACAGAATTAATGGAAAATGATAACGATGATGTTGATGCCAAATCGAATACCGATAATGATGACCATTACGGAACAGATTCTGAACACAGTATGAGTGTGGATTATGAACCTGAAGCAAAACGTTCAGTACTACCGGACCTTGATGCAAAGAAACGAGCGTACATAAAAAGTGCACAATATATTTATGGGAAATTTATTATGAGACAATGTCCAATGTgtgaatttgaatttaattcagCACATTGTtggaaaaaacatttaaattttatgcatCATCTAGAGAAACCCGAacatttacaatttaaatataatgaACGTGGCGCAAAATGTAAATTGTGCGATTTTCAAACACCTACACCAGGCTTTAACAAATTACTAGATCATGAAATTTCTCATATGCCCAATAGtcattatttaaaatgtaaactATGCGATTGGAAGACTAAAACACATTCAAGTATGAATTTTCATTTGCGTGAACAACATGCTGAAACAATTGATGTAACAACGAAAAGTTTGGAATTAACAGTTTGTCCATATTGTAATCAAGAATTTGCATCACAATGGTATTTGCGTAAACATTTAATACAGGAGCATGAAAAAACCATTGATGAGCGAACATCTTTCCTATGCTTAGAATGTGGTGAAGAATTTACAACAAACGTAAGTTTACGTTTGCatgtatttgaaaaatttgcacattACACCCCACAACAGCTTGGTTTCTTGGAGATCCACCCAGCTGAAGGTGACAAAGATAATACAACAAGCCACCTTAAATGTACCCTATGCTCACAAGTTTTCCGTAGAGTTACTGCGAAACGTACAAAAATTAATCTAGCAGAACATTATATGATACATTTGGGGGAACCTTCCGGTAGACATGCTTACAAGTGCAGATATTGTGATGAATCATTTCGAAGATATGATAATATGCGTTTACATATATGCGAAACATTGaagaaagttttgcaaaatggaATGGCTAATATAACAGAAGGAACTCGTTTAAGAAAACGGAAAATGGCAAAAAAAGACAGCCCACTCGAGCCTGTTGTCAACAAAAGAGATTATATGAAAAACATACGATACGTTTGTTTGAAATGTGGTGTGTCCTTTGGTAAGATGTTTCTTTGTAAAAAGCATATGTTCGGCAAACATGCTATGAACCAACCGCCTGGACTGGAATTTAAAAAAGTCGGAAAACAAGATGCCACGGAAATATACGAATGTACCGTATGTGAAGAGTTCACTTGTGACTTTGATTTGAATACCATGCTTGTACATGCACGTACACATACAatatatgatccttttcaatgTAAACTTTGTCGGATGACATTTGCTTATGATGCAGATATACCTGGACATGCATGTTTAGACGAGGAAAGCGCAAAAGCAATACAAGACACTAAAACACCCAAAGAGAATACTTTAGcgaatatggaaaatttttgtcctAAATGTGGACAAACGTACTCAACCTCTTCAAGTTTAACACGTCATATGTATAAAGCACACGGAATGGATGAGCCCTATGGACTCGGTTTTGAAGTTGTCGGATTGAATGATGGTGATGCAGCCGTATACAGTTGTACTCAATGTGTTGCCTTCACGCTGCCAGATAAGAATTTGAGAGCTATGTTGGAACATGCACGTCAGCATTTACCTTTTAAGAGTTATAGATGTACTTTATGCAATGAACGATTCCAATTTAAAAGAGAAGCGAAACTACATCAATGTGCACATGAACCAATGGCAAATGCACCAACACCAGAAATTGAAGATGTAGTTTATCGTGACAAGAATGCAATTAAAGAGCGTTTAAATAAAATGGGACGTTTTTGTCctaaatgtggtaaaaaatttgtaaaaacatttgtatgtaaAAGGCATATAAGTAAAGTACATGGTTTGGATAAACCTAGTGGACTTGGTTTTGAGAAAATTGACGAATCCAGCACAAGCTATCATTGTATGGCATGTTTAAGTTTTACGTTAGATAAACCAGATGTCAGTTTAATGTTAGAACATGCAAGGGAACATTTGCCATTTGATAGTTTTTGGTGTATGCTGTGCGAAGAACGTTTTCGTTCAAAAGTCGAAGCGAAACAACATCGATGTGctaacaatgcaaatgaaatagatAATTCATCACGTACCATATAcccaaaaacatttgaaaaatgtattcggAAATTTTGTCCCGAATGTAATAATGAAATGCCATCAATAAAAACATGGCGTTGGCATATGGCTAAATATCATGAAATGAACGAATTAGATGGACTACAAATGAAGCAAACAAATGCAAACTTAGTAGAATGTTTAATATGTCAAATGCATATAACAAATAAGAGGCGACAAGAGCATAGATTTATACATTTACCGTACAAACCACTGCAATGTAAATTTTGTGGGgaatattttatggaaattgataaagcaaaaatgcattgcTATGAATGTGAACAAATGCCAGTGGAATTGCCAACAGCTGAAAGCGAAGGTAAAGAAAAAAAGCAATCAAAGGCGGAGGCGCCTAAAAAGAGAAAGCCGTCAGCAGTAATACTTGAACAAAGCAAGGATAGCGACAATGAAGAAATTGAAGAGGGCGCAAATTTAGATCTTAAGCTAGCTTTGAATGCCACTATTAAGGAGACAAGAGAGCAACAACACCAAAAGGAAAAGTTGGAAGAAAACTCAAAAATGCCAATTAAAGGCATACGCGTTGTACTTACCGATGATAATGATTATGCAAAATTTGTGCGCATTAGCTGTCCTCTCTGTCCTGATAcagaatttcaaacaaatatggAACTAACTGGACATTTTCATGAATCACATAATAGTTTCTTAGAGCACTTCACAATACATAATACAAATGCGGCAAACTGTAAATCAtgcaataaatatttcaatacagtttataaaaaaacattagTTCGCCATTATCTAGGTGAAATTAATGCCACGTGCTATTGTTGTCGTCTCTGCGATAAAAACtttctatattttaatacaatGCGCACGCATCTACTCGAAGAACATGAAGCTATAATTGCAGGACAATCAAAAGATAACAGCGCGATTACATCATCAGCAGCACGggcgtcatcatcatcagctgGCAACATGATCGGCGGTTCAGCGTATGGTGCAGATccgttaaaattaacaaacaaagatATATCACAAGTATCACGCACTACAATGGCTATACGTACAAATAAAACTGCTGTTTTTAATGAGTTTAATGCATATATATCATATGCTTGTCCAGAATGTAATGAATTTTTTGACACAGCCGAACAATGGCATTTACATATCAATGGTCAACATGATTTCTTTGatcaacaacaattaaatatcgaagCAACACCAGATGGTTATAAGCGTTGCAAACAATGTAATGTTAATATATGTGGTGGTGTATTGGCAGAACAACGCCACAAGCTAACACATATGAAACATAAATCCTTTATTTGTACGTTATGTTTACATCGTTCAACTACCTTGGGTGTACTAACGCAACATTTTCGTAGACGTCATTTTGCGAAAGGTTCATTTAAATGTATTCTATGCGAAGAGGTTCTAAGCACATCATGCGAACAAATCGAACATATTAAACGTGACCATACTCCAGAAGAATATCCACGTACGTTATGTCGTATTTgctttaataattttagttcCATTAATTCTTTAAACACGCATACGGAATTACATAATCCAAATCGTTTTCTCTAtcaatgtaaatattgtgaacgTACTTATAAGTATAGAAGAGAATTCAGTATACATATACAATCTAAGCATCCAGGGAAAAAAGTACCAAACATTAGTGAAAATGAGTAA
- Protein Sequence
- MADSSMSEEESPYEEDTDIENTKVLKSQAVLIENENYADSNTDSEDGEPLANLKPKITLMENDNNNKSSADSEEDGQRKKSNLNYNAAEVDDDDASNSSTEEDEPMININLKTELMENDNDDVDAKSNTDNDDHYGTDSEHSMSVDYEPEAKRSVLPDLDAKKRAYIKSAQYIYGKFIMRQCPMCEFEFNSAHCWKKHLNFMHHLEKPEHLQFKYNERGAKCKLCDFQTPTPGFNKLLDHEISHMPNSHYLKCKLCDWKTKTHSSMNFHLREQHAETIDVTTKSLELTVCPYCNQEFASQWYLRKHLIQEHEKTIDERTSFLCLECGEEFTTNVSLRLHVFEKFAHYTPQQLGFLEIHPAEGDKDNTTSHLKCTLCSQVFRRVTAKRTKINLAEHYMIHLGEPSGRHAYKCRYCDESFRRYDNMRLHICETLKKVLQNGMANITEGTRLRKRKMAKKDSPLEPVVNKRDYMKNIRYVCLKCGVSFGKMFLCKKHMFGKHAMNQPPGLEFKKVGKQDATEIYECTVCEEFTCDFDLNTMLVHARTHTIYDPFQCKLCRMTFAYDADIPGHACLDEESAKAIQDTKTPKENTLANMENFCPKCGQTYSTSSSLTRHMYKAHGMDEPYGLGFEVVGLNDGDAAVYSCTQCVAFTLPDKNLRAMLEHARQHLPFKSYRCTLCNERFQFKREAKLHQCAHEPMANAPTPEIEDVVYRDKNAIKERLNKMGRFCPKCGKKFVKTFVCKRHISKVHGLDKPSGLGFEKIDESSTSYHCMACLSFTLDKPDVSLMLEHAREHLPFDSFWCMLCEERFRSKVEAKQHRCANNANEIDNSSRTIYPKTFEKCIRKFCPECNNEMPSIKTWRWHMAKYHEMNELDGLQMKQTNANLVECLICQMHITNKRRQEHRFIHLPYKPLQCKFCGEYFMEIDKAKMHCYECEQMPVELPTAESEGKEKKQSKAEAPKKRKPSAVILEQSKDSDNEEIEEGANLDLKLALNATIKETREQQHQKEKLEENSKMPIKGIRVVLTDDNDYAKFVRISCPLCPDTEFQTNMELTGHFHESHNSFLEHFTIHNTNAANCKSCNKYFNTVYKKTLVRHYLGEINATCYCCRLCDKNFLYFNTMRTHLLEEHEAIIAGQSKDNSAITSSAARASSSSAGNMIGGSAYGADPLKLTNKDISQVSRTTMAIRTNKTAVFNEFNAYISYACPECNEFFDTAEQWHLHINGQHDFFDQQQLNIEATPDGYKRCKQCNVNICGGVLAEQRHKLTHMKHKSFICTLCLHRSTTLGVLTQHFRRRHFAKGSFKCILCEEVLSTSCEQIEHIKRDHTPEEYPRTLCRICFNNFSSINSLNTHTELHNPNRFLYQCKYCERTYKYRREFSIHIQSKHPGKKVPNISENE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01358524;
- 90% Identity
- -
- 80% Identity
- -