Basic Information

Insect: Merzomyia westermanni
Gene Symbol: wdn
Assembly: GCA_949987695.1
Location: OX465288.1:160120795-160125095[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 4.5e-06 0.00075 21.4 0.4 1 23 379 401 379 401 0.99

2 7 0.095 16 7.8 1.8 2 23 413 433 412 433 0.93

3 7 4.6e-05 0.0076 18.3 1.0 3 23 441 461 439 461 0.97

4 7 6.5e-06 0.0011 20.9 4.0 1 23 467 489 467 489 0.98

5 7 0.00034 0.056 15.5 3.0 1 23 495 517 495 517 0.97

6 7 8.3e-06 0.0014 20.6 0.8 1 23 523 545 523 545 0.96

7 7 0.00015 0.026 16.6 2.3 1 23 551 574 551 574 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	4.5e-06	0.00075	21.4	0.4	1	23	379	401	379	401	0.99
2	7	0.095	16	7.8	1.8	2	23	413	433	412	433	0.93
3	7	4.6e-05	0.0076	18.3	1.0	3	23	441	461	439	461	0.97
4	7	6.5e-06	0.0011	20.9	4.0	1	23	467	489	467	489	0.98
5	7	0.00034	0.056	15.5	3.0	1	23	495	517	495	517	0.97
6	7	8.3e-06	0.0014	20.6	0.8	1	23	523	545	523	545	0.96
7	7	0.00015	0.026	16.6	2.3	1	23	551	574	551	574	0.98

Sequence Information

Coding Sequence: ATGAAAGAAGAAGCGTCAAGTAGCAAAAAAATGCCGCGAAAAACAAGAGCACCACAATTATCAACAGTAGCGCCAAGCACACCCACAAAATTGGGGACCAACGATGAAATATTAACCTCTCTTTTGCGTCTAAACAACTTCGATTCGAATATCAAGGATGAATCATTGGACATCGATTTGTCCGCTTGTGTTACGATTAGCGGCGATTCAGCAGCCATGTTGGGTCACAATAGCCTCTCTAGCACCGATTTTTGGCGTGTTCTAGATGAAAGTGCTCAGAATTCTCAATTGGAATTAACAAATGCCAGTGAtgatttacaacaacaactaatgaATGCTAGCTGTTTAAATGATGATGGCTTGGATGAAAACTCTATTCTAGATGCCGCGGCAGCATATGAGTtggtcaaaagtaataaaatgatAAGTGGtggtaaaaattatatatcaatTACTGGTCCGAAAGTGGTTGGTGGGGTAGtgataaaagaagaaaaacaagaaCCGAACTTCAGTGGAACATTCCTCAGACCAGAAGCACCACCGCCAACACCATCACCAATTAAACGTCTCATgataaaacaacagcaacatgaaCAACAGCGAAATGCCGAGCAACGCTATTCACCTAAAGCTAAAATAAAGCGTGATTTAAAAGACGATATCAATGCAGTTGGCGCACAATCGACGTATCATTTACTAAGAGCCACACAGCTGGACGATGCAGCtgttaataatatacaaattatCGCTAATAAAGTAATGAAGTATACTCCCACCACAACCACACCCAGCAGCATCAACCAGGTTGTagtcagtaacaacaacaaaacgatCTCATCAACATctagtttcaatatttttacattACCAGAAACCAATGCACCAAGTTgtagtaataataatagtagtaaGAGTAGTGGTAGTAGTAACAATAATCATATAAGTTCTGCAACAAACATACCAGCTAAGATTGGtactagcagcaacaacaacagcaaagagGTTGGTGCATCTCAAGAAGTCGGTACAAGCGTACCCGAACCTTTATTTAAGTGCCTGAACTGTGATGGTCTCATACTGCAGGGACGTGGGGAATATGCTACCCATGAGGCTATTGGTCATCGCATACATTATCGATGCTCAGTGTGTGACCGTGATTTTGAGCAGGAAGCTGGCTTGAAGAAACATATTAAAACGCATCGTTCTACCGATCCGCGTAAAGATGCCTGGAAAAAATGTCCCGACTGCGGCAAATGTCTAAAATTGGGCAGCATGTGGATGCATCGCAAAATTCATAGTGATAACAAGAAATACGGCTGTGATATATGTGGTCAAAAATTTGTACAAAAGATAAACTTGACTCATCACTCACGTATCCACACCGCTGAGAAGCCTTACGAATGTCCGGAATGTCAAAAGAGGTTTCAAGAGCGTTCACATCTTCAACGCCATCAAAAATACCATGCTCAGACACGCTCGTATCGTTGTGAAAAATGTGGCAAAATGTACAAAACTGAACGTTGCCTAAAAGTCCACAATCTGGTGCACCTCGAACAGAGACCATTTGCATGCACAGTCtgcgataagtcatttatcagCAATTCGAAGCTAAAGCAACACTCCAACATTCACACCGGAGAACGACCATTCAAATGTAATTATTGTCCACGCGACTTTACTAACTTTCCCAATTGGTTGAAACATACGCGTCGTCGCCATAAAGTGGATCACAAAACTGGTGAACATTTGGAAAACATTCCATCATATTGCTCCAAGAAGTCCACAAAAACTGCTAAGGCGAAAGCCATCGACGCAGGAAATACAGATACACCGCAGAACCCAATTAACGCAGAGGTGAATAATACCCTACAAAAACAAGATGCCAAAGTCGGTGGTGAAGTTAGTGGGGCAACTAGTGCAACTCCGAAGACTTCATCAGTTACTAAGCGCAAAAAGAAATCTCCACAACCACAACAGAAACCAATGACATACGCTACATTAACACCGCCAACACCACAACCGCCGCCACCACCACCTTTGGTATCACTTAGTAGTGATAATCGTCCATTACCAACTATCACTGTATCGACAATGTCTGGTATTATTAAATCAGAAGTAACCCGCAGTATGAATAACATAATGACAACGATTCCTTTATCAATGACACCACACTTAAAGCCATTAACATCTGGCATTACAACCATTAATAAATTAAGCAAAGTGGTGGAAACATGCAAAACTGCTAAACCTAAGCGTGAGCGTAAGCAACCATCACCGAAGCAAGTCCAAAAAGCTACATTCCCCACCCCGACATTACTATCGTCCATTAAACGTGAAATTACGGAAGCGGATGTTAACAACGCAAAATCGAATGTGAACACAGCTATAATACATGCCGATCCACGTTATGCGATTAGCAATTTTCCGGATTTAAGTATAACATCAGCTGAAGAATTGATTATGGAACAAGCGCTTGAAATGGAAGAGTGTGGATGGAATGTGGGACAGGCGCAACAACCTTCCGTTGCTCTGGAGACTGACAATGCGATTTCATCATCAGAGGCTACAGCAGcgttacattttaaaataaaaagcgaaTTTGATCCTATGGATTTATCAGCGACGACACGCATCAAAGAAGAATACATTACGCTAAAGGACATGAATCAACGTTTGTTATGTTCGTCATTAGAATCGTCCCCCTACTCATCACCAGCATCTGTTGAAATGTCTGCAGCGCCAACAATTATGTCATTGACGGGACAATCAGGCACCGACACAGATAACTTACAATCAACATCTGCACCTTCATCAAATGCTTACAACATTAATCCATATGCTCTAAATACaaagaatcaaaaaattttaacaaacctGGGCAATACATTATCCCATCAAACTGTTGCTGAATTACAGAGTATGTTACCTCAAATTACAACACAACTGGTTTCAACAACACAAAATCAGAATTCAAATGTTCTACCTACCACCACCACACAAGCAATAATCAACCATTTCTATTTGCATCCTATAACTGCAATGAGTATGCCTCTGCTTACGCAAGCATCCTCCGCCAATCAAAAATTGCCTTCTGTGGATACTTTGCTATTTTCTGCTGCTGCTGCCGCCGCCGCTGCTTCTGCGACTACTTCAACGAACACTAGTACCACATCAAGCGCGTCATTAACGCAAAGTAGATTCTTCCATGGTAAAAGTATAGCGTCCAACGCATCAACGCCAACAACGGGCACATCGACACATAGGCAACCCAAACTCACTTGA
Protein Sequence: MKEEASSSKKMPRKTRAPQLSTVAPSTPTKLGTNDEILTSLLRLNNFDSNIKDESLDIDLSACVTISGDSAAMLGHNSLSSTDFWRVLDESAQNSQLELTNASDDLQQQLMNASCLNDDGLDENSILDAAAAYELVKSNKMISGGKNYISITGPKVVGGVVIKEEKQEPNFSGTFLRPEAPPPTPSPIKRLMIKQQQHEQQRNAEQRYSPKAKIKRDLKDDINAVGAQSTYHLLRATQLDDAAVNNIQIIANKVMKYTPTTTTPSSINQVVVSNNNKTISSTSSFNIFTLPETNAPSCSNNNSSKSSGSSNNNHISSATNIPAKIGTSSNNNSKEVGASQEVGTSVPEPLFKCLNCDGLILQGRGEYATHEAIGHRIHYRCSVCDRDFEQEAGLKKHIKTHRSTDPRKDAWKKCPDCGKCLKLGSMWMHRKIHSDNKKYGCDICGQKFVQKINLTHHSRIHTAEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGERPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTKTAKAKAIDAGNTDTPQNPINAEVNNTLQKQDAKVGGEVSGATSATPKTSSVTKRKKKSPQPQQKPMTYATLTPPTPQPPPPPPLVSLSSDNRPLPTITVSTMSGIIKSEVTRSMNNIMTTIPLSMTPHLKPLTSGITTINKLSKVVETCKTAKPKRERKQPSPKQVQKATFPTPTLLSSIKREITEADVNNAKSNVNTAIIHADPRYAISNFPDLSITSAEELIMEQALEMEECGWNVGQAQQPSVALETDNAISSSEATAALHFKIKSEFDPMDLSATTRIKEEYITLKDMNQRLLCSSLESSPYSSPASVEMSAAPTIMSLTGQSGTDTDNLQSTSAPSSNAYNINPYALNTKNQKILTNLGNTLSHQTVAELQSMLPQITTQLVSTTQNQNSNVLPTTTTQAIINHFYLHPITAMSMPLLTQASSANQKLPSVDTLLFSAAAAAAAASATTSTNTSTTSSASLTQSRFFHGKSIASNASTPTTGTSTHRQPKLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01358366;
90% Identity: iTF_01358366;
80% Identity: -