Basic Information

Insect: Merzomyia westermanni
Gene Symbol: Sp4
Assembly: GCA_949987695.1
Location: OX465293.1:60898829-60900933[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00082 0.14 14.3 1.6 1 23 108 132 108 132 0.95

2 5 1.3e-07 2.2e-05 26.3 0.4 1 23 138 162 138 162 0.98

3 5 3.9e-05 0.0066 18.5 3.3 1 23 168 190 168 190 0.95

4 5 4.7e-07 7.8e-05 24.5 1.7 2 23 382 403 381 403 0.97

5 5 6.2e-06 0.001 21.0 2.9 1 23 409 431 409 431 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00082	0.14	14.3	1.6	1	23	108	132	108	132	0.95
2	5	1.3e-07	2.2e-05	26.3	0.4	1	23	138	162	138	162	0.98
3	5	3.9e-05	0.0066	18.5	3.3	1	23	168	190	168	190	0.95
4	5	4.7e-07	7.8e-05	24.5	1.7	2	23	382	403	381	403	0.97
5	5	6.2e-06	0.001	21.0	2.9	1	23	409	431	409	431	0.97

Sequence Information

Coding Sequence: ATGTCGACAGTAGTAAGTGACACGCCCACGCCGCAGGAGATGACGTCAGCTGCAATGGTGGTGTTTCCAATAAATACCTGTGGGAGTGCCGATAATATGTATAATCAAAATCATTCAGAAGATTACAGTTCGGGTACATTCGTATCAAATGTGCAATCAGAGATAAAGATGGAACCACCTGAGGATATAAACGACGTCGGTGATAGCGCCTCAAATTTGTCGGACAAAACTCCCAGTGATAATTCTGATGGTCCTAAAATTCGCTTGACACCTACTATTAAACTAATGCCATTGACAAACCCAGTTGACCCCAAGAGAAGATTTGCTTGTCCTTACGATAATTGCACAAAAAGTTATGGGAAGAGTTCACATTTGCGTTCTCACTTGACTTGGCATACAGGTATTAAACCATTTGTGTGTACAGAATTGAATTGTGGAAAGGGGTTTACCAGATCCGATGAACTTAATCGTCACGTAAGAACACATACGGGAGAGAAGCCCTTCGAATGCATACAGTGCACGAAAAAATTTTCACGCAGTGATCACCTAACAAAACATCTAGCCACTCATGTAAAgcaaatgcaaaataaatcgGACGGTCCTAAAAAGGCACGTAAAGATGGATGCCCGATCAATGCAAgaaaagaatttttgaaaaatgatttatCAATTAGTTTGGAGGACACCAAGTTCCCGAATGATGGATCAAAACAAAGCCAAGAGGATTTTCTACATCAGCAACACGATCTGTTAAAAGTACAACAAGATATGTTACACCAACAACAGCGAAATCTCGAAGATTGCGATTCTAGAAATGGCATGCATTTTATGGCGTCGCTAATTGAAAAGGGTGGTAAGAAAGACACTGTAAAACCAATTGAGCCTCTTCTAGACCATAGGCCTATACCCATAAAGATAAAATTAGAAAGACCGGAAAACAGCAATGAGTATCATGTCGTTCAACCAGATACACCCTTGAAATCAAATTCTTGTGATGCTACGAGCGAACTAGCGATACCAGTCCCTAATATAAAACATGAGGATACCGCGCAAGACTCAAGTACACCTGTCTTACGTGCTAATAGTGCGTACATGGATTGGCCTGACGTTGGACAGCAAGGAGGTGTTTATGACCGTCCTTGGCGATGCAACTCGTGTGCGAAGACATTTAAACGACAAGATGATCTCAATCGCCACCTTCGTACACATACTGGAGAGAAACCATTTGTGTGTGTGGCCTGTAACCGAGGATTTAAGCGcagtgaccatttaaagaaacatCTCAAAACGCATACAAATTTCCGGTAG
Protein Sequence: MSTVVSDTPTPQEMTSAAMVVFPINTCGSADNMYNQNHSEDYSSGTFVSNVQSEIKMEPPEDINDVGDSASNLSDKTPSDNSDGPKIRLTPTIKLMPLTNPVDPKRRFACPYDNCTKSYGKSSHLRSHLTWHTGIKPFVCTELNCGKGFTRSDELNRHVRTHTGEKPFECIQCTKKFSRSDHLTKHLATHVKQMQNKSDGPKKARKDGCPINARKEFLKNDLSISLEDTKFPNDGSKQSQEDFLHQQHDLLKVQQDMLHQQQRNLEDCDSRNGMHFMASLIEKGGKKDTVKPIEPLLDHRPIPIKIKLERPENSNEYHVVQPDTPLKSNSCDATSELAIPVPNIKHEDTAQDSSTPVLRANSAYMDWPDVGQQGGVYDRPWRCNSCAKTFKRQDDLNRHLRTHTGEKPFVCVACNRGFKRSDHLKKHLKTHTNFR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01358353;
90% Identity: -
80% Identity: -