Mwes001378.1
Basic Information
- Insect
- Merzomyia westermanni
- Gene Symbol
- -
- Assembly
- GCA_949987695.1
- Location
- OX465288.1:39270113-39292978[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.6 1e+02 5.3 0.3 1 23 824 847 824 847 0.93 2 11 7.9 1.3e+03 1.8 2.3 1 23 881 905 881 905 0.76 3 11 0.00017 0.028 16.5 0.9 2 23 912 933 911 933 0.96 4 11 0.0011 0.19 13.9 0.5 1 23 939 962 939 962 0.89 5 11 0.0041 0.69 12.1 2.2 2 23 970 992 969 992 0.95 6 11 3.5e-06 0.00059 21.7 2.2 2 23 1004 1025 1003 1026 0.94 7 11 1.6e-05 0.0027 19.7 2.0 1 23 1050 1072 1050 1072 0.98 8 11 0.11 18 7.7 5.2 1 19 1080 1098 1080 1103 0.93 9 11 3.8e-06 0.00064 21.6 1.2 1 23 1109 1131 1109 1131 0.99 10 11 8.3e-05 0.014 17.4 1.6 1 23 1138 1160 1138 1160 0.98 11 11 0.0033 0.55 12.4 5.8 1 23 1165 1188 1165 1188 0.95
Sequence Information
- Coding Sequence
- ATGGATGGCAGCGTGTACTGTCGCACCTGTGCAGCACCATCACCTGGAGGAGACGACGACGACATCGTCTTAAATACCAAAGGATTGAACGATATTTTCGCAAACgaacaaatcaaaaaacttttaagtacATTGAAGGAATGGCAATTAGATATTATGGAGGACGATGGTTTGCCGCAATGTATTTGCGAGACATGCGAAATGGCGCTTAAACGTATTGATGATTTTAGGATACAAGCATTGAGAGCTAAGGAATATTTACAAATGCGTTTACGTTCAATTGTCAATTGTATAGCGACGACGGAGGGCGTTGTGGTAGaagtaatgaaaattaataacaatGAAAATGACCTTCATGTTGGCGATACAGTAACAAAACCATATTTTAACGGGAGCTCGCCGGAGATATACCATAGGGAAGCCGTATTAAGCCGCAAAAGAGTGACGCCGCCGCCGCTACCAAAAACAACGTATGAGTATGATGATTCAACAAAgcatgtgaataaaaaaattaataataatatggcAAGTGGTGATAACGGGAGTATGGAAAAAGCAGAGCTAAACGATATAGAATTAGTCGCATGTGCAGCCGTCGTTAATGAAGACGGCGATCTAATCGAATCGAGCAGACCACCTGAATTCCAGATAGTACTAATTGAAGAGCACGAAGAGGGCCAATTGCAGTGGATTATCGAAGAGGATGAACATAGTATGGCCGTAGGTGGTGAGAAGAAGGAAGATTCATTACGAAATAATGAATTCGGGCTTACAGCAAGAACAGAATGTTGCATaggcggcaacaacaacaatatcaaaaaGCAGAGAGATGCAGACGAGCACGAGGGCATGCAAAGTAATACGAATAAGAACATTGCTATTAAAAATCAGCATACAAAAGTCAACAAAAACCTAGAAAATAGTTCTAACAAGCAAGCGCAGGAAGAAGTTGATGTCgtaattaaagaaaattcacaatatgAAGCTTGTGTACAAGAAGAGCGTGAGACACAAATTAACACCAAAGCGAAAGCAAATACGGAGCACATTTTACATGGAATTGCACAGCGTAAAAACGGGTTAGGTCATGAGCAGGAAGGTTGTAAAATTAATGACCCAGATTCATATCTAGCAGAGGGCTGTTACGTTGGCAGCAATCTTCAAAACTTTCAGGGACTTATTTTGccattaaaacaacaacacgcACATAATGAAGTTAATGACCACGATACATATCTTGCCACGGACTGTGATGCAGCGCAACGGAAAATGAAGTGCACCGGCAGCGATCATCAAAGCTTTCGTGACGTGAATTTAccattaaaacaacaacaacaccaaagtGAAATTAATTTGAAGACAAATTTTACAATTGATTTACTTCCATCGCTTGACGAAGATCTCAttggaaaacataaaaattataataacaaatcaCCTGGGATGCatacagaaataacaaaaacgacaacAGAAATGTCACTACAACATTTAACAAatccaaatgaaaaattaatacatgaagAACACACACAAATTAAGGAATTTCAAGCATTACTAGCTGCATTGAACGAACAGGTTAGCGCTTTTGAAACAAATTCGAACTATTCATGTGGCGATTTAGACTTAGACTTGCAATCAATATTCATGAATGATTTAACgctacaaatgattaatgcgAATGTAAATATTATAGAAGAAGATTTGCAAATAGATCAACTCGAAACATTGCTTTCATTGCCAGTTGATGATGCAGATGAAGATAAAACTGTGTTAGAACTTTCAGAAGAGAAAACGCGCAATATAATAAATGAGCGAACAGAACATAATTCTGAAGTAAATAATGCAAATATATTTGCAGAGAGTAAAAATGAGTCATGGCAAGCTGAAAGTCAATACCATAATCAACAGGATGTAGAGTACTACGGCTCGAACAAAAGTGCTAATAGATTAAGAGACTTAAAGCAAACCACTACAAATTTAACGACAACGGAAACTGTATCTAAAAATTATGAACATGAACAGCTTGAGGACTTCACACAAtgtcaaataacaacaacaaaacaagagCATTCATCATTAGAAAAATATGTAGACGATGATAGTGGCATGTCACTTGTCTTAGAGGATAAACTGATAAATGAGCCACTTAGTAACTACTTAAGTATAGATAATACAAGCTTTAGTAATAGTTTAAATAGCAACtttacaccaacaacaacaacaataataacacttGTGGACAACCACAATAACAAACTGCATAAACCTACAAATACAGCCACTTGTGCACGAGGTCGTCGTCGTAGTTCAGCAGTTATCCCGccgcataataaaaaaaattccaaaattacaaatattttgcgTTGTCGTTTTTGTGTCTGTAAAATATCCGAACAGCCAATTTTTCCAACAACGCATCTACTCGATCAACATATAGCAACAATACACGATGATAAAGATCGTCCCTATAATTGTCCACAATGTGCAGCACGTTATCGTACACGTAGCGGTTGTGTGGCACATATAAATGCTATACacttgaaaaaattcgaaaattgtaaattatgcAATAAAATTGTTGCAGGCGGTTCAGGTCAAATGCGTATGCATATCGAACGCAATCATACACATGGCAATTACACTTGTGAAATTTGCCAtttagaattgaaaaatgttacACTGTATAACTTTAAATACCATAAAAGATGGCATGATGAGGGTAAATTATGGCGTTGTGAATTATGTGAGAAAGCATTTGTGACACGTACACATTTAATGGCACACAAAGTGACACATACCCGTCAAGGAGAATTTCTATGTACGCGTTGTGGAAAGAGTACACGCAGTAATTGGGAGCTACGTACACATCTCTACGCAATTCACGGCGAGGGCGATGCGCCACTACAGTGTAACTATTGTGACGAAaAATTCACACAACATATTCAAAAACGTGTCCATATTGAGCGTTATCATCCCAATGAGCAGCAGACTAAACGCACCACTGTGCCATGCTCCAAATGTGATAAACAATTCTCCACAGAGATAAACCTTCAGagacatataaaaaaacatcATAATGAAGGTAGTTTCGATATTTTAATGAAGAAAGTCGCAGCAGCTTCATCACCACCACAATATGAAGGTTTCATGTGTGCACATTGCCCGCGTAAATATCGTTCTAAATATGCGCTCATCAAACATTTGCGTGTACATACCAAGATGCCAGATAAACCATATTCGTGTCCAGATTGTTATATGCATTTTAAACATTTCTCCGAATTAGATCGTCATGATTTGCAGCATCATGCCACAGtgcgcccatacaaatgcgatGAATGTGCGAAAAGATTCTCAACAAGAACAGCACTTAAAATTCACAGACGAATTCATGAAGtaAAGGGCAGAAACTTTCGTTGTCCAGAATGCGATCAACGTTTCAAATTTGAGAAATCATTGAACTTACATCGCCTTTCACACAAAACTATGCGACACAGTTGTGATATTTGTAATAAATCGTACATTCGTTTAACGCAGTTGAAAACACACAAACATCGTTATCATCAAATTCAAAGTGATTCGGAGGAAGAGTAA
- Protein Sequence
- MDGSVYCRTCAAPSPGGDDDDIVLNTKGLNDIFANEQIKKLLSTLKEWQLDIMEDDGLPQCICETCEMALKRIDDFRIQALRAKEYLQMRLRSIVNCIATTEGVVVEVMKINNNENDLHVGDTVTKPYFNGSSPEIYHREAVLSRKRVTPPPLPKTTYEYDDSTKHVNKKINNNMASGDNGSMEKAELNDIELVACAAVVNEDGDLIESSRPPEFQIVLIEEHEEGQLQWIIEEDEHSMAVGGEKKEDSLRNNEFGLTARTECCIGGNNNNIKKQRDADEHEGMQSNTNKNIAIKNQHTKVNKNLENSSNKQAQEEVDVVIKENSQYEACVQEERETQINTKAKANTEHILHGIAQRKNGLGHEQEGCKINDPDSYLAEGCYVGSNLQNFQGLILPLKQQHAHNEVNDHDTYLATDCDAAQRKMKCTGSDHQSFRDVNLPLKQQQHQSEINLKTNFTIDLLPSLDEDLIGKHKNYNNKSPGMHTEITKTTTEMSLQHLTNPNEKLIHEEHTQIKEFQALLAALNEQVSAFETNSNYSCGDLDLDLQSIFMNDLTLQMINANVNIIEEDLQIDQLETLLSLPVDDADEDKTVLELSEEKTRNIINERTEHNSEVNNANIFAESKNESWQAESQYHNQQDVEYYGSNKSANRLRDLKQTTTNLTTTETVSKNYEHEQLEDFTQCQITTTKQEHSSLEKYVDDDSGMSLVLEDKLINEPLSNYLSIDNTSFSNSLNSNFTPTTTTIITLVDNHNNKLHKPTNTATCARGRRRSSAVIPPHNKKNSKITNILRCRFCVCKISEQPIFPTTHLLDQHIATIHDDKDRPYNCPQCAARYRTRSGCVAHINAIHLKKFENCKLCNKIVAGGSGQMRMHIERNHTHGNYTCEICHLELKNVTLYNFKYHKRWHDEGKLWRCELCEKAFVTRTHLMAHKVTHTRQGEFLCTRCGKSTRSNWELRTHLYAIHGEGDAPLQCNYCDEKFTQHIQKRVHIERYHPNEQQTKRTTVPCSKCDKQFSTEINLQRHIKKHHNEGSFDILMKKVAAASSPPQYEGFMCAHCPRKYRSKYALIKHLRVHTKMPDKPYSCPDCYMHFKHFSELDRHDLQHHATVRPYKCDECAKRFSTRTALKIHRRIHEVKGRNFRCPECDQRFKFEKSLNLHRLSHKTMRHSCDICNKSYIRLTQLKTHKHRYHQIQSDSEEE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -