Basic Information

Insect: Merzomyia westermanni
Gene Symbol: grau
Assembly: GCA_949987695.1
Location: OX465293.1:111156685-111159221[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1.5 2.4e+02 4.1 0.1 2 23 282 304 281 304 0.85

2 10 1.3 2.1e+02 4.3 2.7 6 23 313 330 305 330 0.95

3 10 0.0024 0.4 12.8 3.7 1 23 336 359 336 359 0.95

4 10 4.7e-05 0.0077 18.2 0.9 1 23 367 389 367 389 0.98

5 10 7.4e-06 0.0012 20.7 0.3 1 23 394 417 394 417 0.98

6 10 0.065 11 8.3 0.1 2 23 424 445 423 445 0.95

7 10 6.6 1.1e+03 2.0 6.0 2 23 454 475 453 475 0.90

8 10 0.00012 0.02 16.9 0.1 1 23 482 505 482 505 0.95

9 10 2.2e-05 0.0036 19.3 0.4 1 23 511 533 511 533 0.98

10 10 1.9e-05 0.0032 19.4 4.3 1 23 539 562 539 562 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1.5	2.4e+02	4.1	0.1	2	23	282	304	281	304	0.85
2	10	1.3	2.1e+02	4.3	2.7	6	23	313	330	305	330	0.95
3	10	0.0024	0.4	12.8	3.7	1	23	336	359	336	359	0.95
4	10	4.7e-05	0.0077	18.2	0.9	1	23	367	389	367	389	0.98
5	10	7.4e-06	0.0012	20.7	0.3	1	23	394	417	394	417	0.98
6	10	0.065	11	8.3	0.1	2	23	424	445	423	445	0.95
7	10	6.6	1.1e+03	2.0	6.0	2	23	454	475	453	475	0.90
8	10	0.00012	0.02	16.9	0.1	1	23	482	505	482	505	0.95
9	10	2.2e-05	0.0036	19.3	0.4	1	23	511	533	511	533	0.98
10	10	1.9e-05	0.0032	19.4	4.3	1	23	539	562	539	562	0.97

Sequence Information

Coding Sequence: ATGATATGTCGACTTTGCCTAAAGGATAATATCGATGTTATCCACATATTCGAAGAGGTTGGTACAGAATTAAATGTGGCTGCTGTGCTTAGCAAATACTTCTGGTTCGAGcCCAGGAACGATGATCCAATATCTACTGCAATATGCAAGTCTTGCTGGTCAAGCGTGTccaattttaatgatttttactTGGGCGTTGAAGAAGCGCATAGGCTTTTGACAGAACGATTTTCATTGAAGGCCGAGGACAAAGAGCTAAAATTCCACAAACGACGTCGGTATTCCTCTGTTAGTGATGAAAAGGAAGTTGATGAGTGGTTGTCTACAAGTTTGTCTACCAGCGTTTCCAAAAATGCgaaaactgaaacaaaaactgtcGATGAGGAGGAGGATCGCAAAAATAAGCTGACtgaggaaaaaatttataatgaaACGAAACCGTTGAAACGTGAAGACTCATTTGAGTACgatcagttatcggtaaatagtGAAACATTCATGGAAGAAGTGATGGGGCTGGTAGAAGATAGCGAAGATGCACTTGCTTTACCAACTAAGAAGGAATGCCGTAAAGGTCGTTCTAGTAAAAGGCAAAAtgtaacacaaaacaaaaatggttcgATTATTAAATCGGAAAATGATTGTAGCCCTGACACAAAACCAAAAGCAGATGTAAAAGAAGTGCCCAAGAAACGTCGTGGTCGACcatcaaaaattaaagaagtcTCTTTTGAAAGTCAGAAGCCTAAAAAGGAAACCAAAAAGCGCAGCAATTCAGAGCAAGAAAGTTATGAAGGGCGCATGCGTCAAATCGATGAAAAGATCGCGCAGTGTATACGCTTAACATGTGATGTATGTGCGTTAGAGCAACCGACATTTTCAGCATTGCGTAAACATATGGAACAAGTGCATCAATGTAAAGGATATGCGACttgttgtgaaaaaaaatttcataaaaggtCGTTGCTACTCGGACATATTGAGAAACATATAAATCCGGACTGCTATAAatGTGAATCCTGTGACAAAACATTTGCCGATAGACAATGTATGCGCAATCACTTCTTGATCAAACATCAACCGGAGGACGAAAAACAATATCAATGCGAACATTGTCCAAAGCGATTTGCACGCCCGTATATACTTGAACAACATCGCCTTATACATGAAGAACGTAAATATCAATGCGAGGTCTGCAAAAGGGGTTTTGCTACAGAAACGTTGCTCAACACACATATGAAAATTATGCATTCGAGTTATGGCGCTACCATGTGCGATATATGTGCAAAGGTAATTCGAGGGCGTGCTGCTTTTGAGCGTCATCAATTAGAGCACACCGGCATTGTATTGCCAAAGGTGCAATGTGATAAATGTGGTTCTTGGCACAAGGATAAGTATAGCTTGCAAAAACATAAGCGTCGACATAACGACGATGGTACTGTCCACGTATGCCCCATTTGTGGTAAGGTGGCACCTAATCGTAGTGCATTGCTTGCTCATAACCGTTACGTACATAAATCTGCAAGAGTTTTTGAGTGTGGTGTTTGTAAGAAAGCTTTTAAAAAGGCCATCACTTTAAAGGAACACATGACAATGCATACCGGTGAGGTACTATATAGTTGCCCGCATTGTCCGAAAACGTTCAATTCCAATGCCAATATGCATTCACATCGTAAGAAAGTGCATCCTATAGAGTTTGAAGAAACGCGCAAACAGCGACGTGAAAATTCTGCAAGAACTGATAAACCTACTGAGCAAAAAGACGAGAATGAAGAAACGAGTTTGGAGGAGCAAAGTCAAACAAAAGTAGAAATAGTCAACAGCAGTGATGATGACTCTAAAGAGCAAATTATTGTCATAAAATCGGATGATGGCAACGAGACACACAGCATATTAGTAACCACAGAAGGATTCAGCGACAACGATGATGATGGAGATATGAATGAAAATAGTATAGTTTTCTCTATTAATTAG
Protein Sequence: MICRLCLKDNIDVIHIFEEVGTELNVAAVLSKYFWFEPRNDDPISTAICKSCWSSVSNFNDFYLGVEEAHRLLTERFSLKAEDKELKFHKRRRYSSVSDEKEVDEWLSTSLSTSVSKNAKTETKTVDEEEDRKNKLTEEKIYNETKPLKREDSFEYDQLSVNSETFMEEVMGLVEDSEDALALPTKKECRKGRSSKRQNVTQNKNGSIIKSENDCSPDTKPKADVKEVPKKRRGRPSKIKEVSFESQKPKKETKKRSNSEQESYEGRMRQIDEKIAQCIRLTCDVCALEQPTFSALRKHMEQVHQCKGYATCCEKKFHKRSLLLGHIEKHINPDCYKCESCDKTFADRQCMRNHFLIKHQPEDEKQYQCEHCPKRFARPYILEQHRLIHEERKYQCEVCKRGFATETLLNTHMKIMHSSYGATMCDICAKVIRGRAAFERHQLEHTGIVLPKVQCDKCGSWHKDKYSLQKHKRRHNDDGTVHVCPICGKVAPNRSALLAHNRYVHKSARVFECGVCKKAFKKAITLKEHMTMHTGEVLYSCPHCPKTFNSNANMHSHRKKVHPIEFEETRKQRRENSARTDKPTEQKDENEETSLEEQSQTKVEIVNSSDDDSKEQIIVIKSDDGNETHSILVTTEGFSDNDDDGDMNENSIVFSIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01358387;
90% Identity: iTF_01358387;
80% Identity: -