Basic Information

Insect: Merzomyia westermanni
Gene Symbol: ZFX
Assembly: GCA_949987695.1
Location: OX465291.1:148763416-148769371[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2.5e-05 0.0041 19.1 2.6 1 23 233 255 233 255 0.98

2 12 2.7e-06 0.00045 22.1 3.2 1 23 261 283 261 283 0.98

3 12 0.0015 0.25 13.5 3.2 1 23 335 358 335 358 0.96

4 12 0.00086 0.14 14.2 1.2 2 23 598 619 597 619 0.97

5 12 0.011 1.8 10.8 2.4 1 22 624 645 624 648 0.92

6 12 0.027 4.5 9.5 6.5 1 23 731 754 731 754 0.96

7 12 0.0058 0.96 11.6 5.2 1 23 760 782 760 782 0.98

8 12 2.1e-05 0.0035 19.3 3.3 2 23 789 810 788 810 0.98

9 12 1.8e-06 0.0003 22.7 3.4 1 23 816 838 816 838 0.96

10 12 0.0008 0.13 14.3 3.0 1 23 844 866 844 866 0.98

11 12 6.3e-05 0.011 17.8 2.6 1 23 963 985 963 985 0.99

12 12 2.2e-06 0.00036 22.4 0.7 1 23 991 1013 991 1013 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2.5e-05	0.0041	19.1	2.6	1	23	233	255	233	255	0.98
2	12	2.7e-06	0.00045	22.1	3.2	1	23	261	283	261	283	0.98
3	12	0.0015	0.25	13.5	3.2	1	23	335	358	335	358	0.96
4	12	0.00086	0.14	14.2	1.2	2	23	598	619	597	619	0.97
5	12	0.011	1.8	10.8	2.4	1	22	624	645	624	648	0.92
6	12	0.027	4.5	9.5	6.5	1	23	731	754	731	754	0.96
7	12	0.0058	0.96	11.6	5.2	1	23	760	782	760	782	0.98
8	12	2.1e-05	0.0035	19.3	3.3	2	23	789	810	788	810	0.98
9	12	1.8e-06	0.0003	22.7	3.4	1	23	816	838	816	838	0.96
10	12	0.0008	0.13	14.3	3.0	1	23	844	866	844	866	0.98
11	12	6.3e-05	0.011	17.8	2.6	1	23	963	985	963	985	0.99
12	12	2.2e-06	0.00036	22.4	0.7	1	23	991	1013	991	1013	0.97

Sequence Information

Coding Sequence: ATGGTTCCGCTACCATCACACCATCAACaaccaaaaaatgtTTTTTTGAGGAGGGATGTGTCCGAGCATATTGTAATTTCTGAGCATAGGGCAATTTCTGAGTATAAATTTGACGAGGAGCATCTTTGTCGACTTTGTGGAGAACTGCAACAAAATGTTATATCACTTTATGGCGAAGACCGTGAAGATTTTGTTAAACTGGTTACGCTCACGCTTGGATACTTAAATATAGAGTTTACTGATAAAGACGTGTTTCCAAAATGGCTATGCGCTACGTGCCATGTGCATGCTGAATTAACCAACAAATTTTTGCTTATGGTACAGGAAGCGCAAATAAAGTTACGAGAAGTGGTTCAGGCGGAGCGCGAAACGTGTCGGTACTTAATAACTGAACTACAAGAAAACAATCAAGTTATAAAACTTGAAAGCGACTGCCTACAAAGTCCTCAAAATTTAAGGAAACATGAAATCTTCGCAGCTAAAAAGATTGAGGGAGGGAAAGCAGACACACAAACTTCAATGAATGATAGCGATACGGCTTATATTAAAACAGAAGAAGATTTTGCAATTCACTTTTCCACGATGGTCAGGAATAAGTTACAGAAAGGGCCGGATTTAAGTTCACACAATGACTTGCAACACCGCAGCACACCGCAACAACAAGCCCTTTTTGCTTCAAATAATGATACAGATCTATACCAGTGTCATTATTGTGGCGCAACTTACAAGAATGAACATCTTTTAAATGCCCATTTGGCTAAGCATCTGGGTAAACTATACTTTAAATGCAACAAATGTACTAAAAGATTTGCGCATAATGACGAGTTGACTTTGCACATGCGTGCGCATGAAGGGGACCAGTCTTCTGTGAATGAGCACTATCGTGAAACCTCTGCATGCCCTTCGAATTCCAATCAGCTGGCACAAAAGTATGAATTGCAAGCTTCAACGCCAAATGCAACGCCATCAGATTCATCGCTCTCTCGTACAGCCGAAAAGCTCTACAACTGTACAATTTGTCTAAAGAAATATGCTCATGAAGCACATCTTAAAGCACATCAAAACCTAaagcataaaaatatttcatttccaTTCAAGTGTGCGGAGAATGAGATACAAATTTGGGGCGAAAACAGGGACGATTTTGTAACATTGATCAGCTGCACGTTGGGTTACTTAAATATAGAGTTTGTGGATGACGATGTATTGCCTAAATGCATATGTGCTCCCTGCCAATTAGATGCCGAatcaaccaaaaaatttttgcttttggtAGAGGAAGGTCAACGTAAATTACGTAAAATTGTTGAAGAAAGCTATGCAGCTTTGGGAAAACCTAGCAGTTTGCAAGGCAATCGGAACAGCAATCAAGAAGAGAGCATGCCGTATAAAGGAAATTCAGCTGAAAGTTCACttaataataattgtaaaagtCTCATAAAACTCCTCAATACCTCTGATAATAAAAACGTTGAGATCGAGGAATATCCCATTGACATACACACATCTGTGACTGATATATCTACAAGCAAATATCCTAAACGTAAAAGACAACCAACCAAACGTTTTCCATGCGATCCTACGCCTTACGCAGGGGCAGAAGATTATGCATCAGGCGATGATACAGACACGAAATGCGACCAATCAGGAGATATAAGGGCTGGCACACTCATCACTATAAAACCAATAGCCGAACTATGCGCTGCGAACGGAGCTTCTTTAGCAGAAATGATTGCCGTTGATACGGAAGTACCACAGCGCATAACATCCACCGAACCAGAGATTCGATTAGTTTGTGAAtattgtaaagatatttttactaCACAACGTCTATTCTTGAAACATCTGCGCACACACAATGAAACTATATACCAATGCATGGAATGTGAAAATTGTTACGAAACACTAACCgaattaaaaaaacatcaaaaacttGAACAGCATAAAGGAAAAACTATACTggcaaaaagtaaaacaaaaacaagcaacAAGTGGACACCAAAAAAGGATCTAAAAACTAACTCAGAAAATATAGCAATTAGTATAGCCTTAGATGATGATGGATCAATTGATTCTGATGTAAAACCAACGGTCAAAGATGGCGATACAAGGAGTGATCAAGTAGGACCAAATTATCAAACTGAGCaaatagaaataaagaaaaaaggttTGCCTTCAACTAAAACTGCATATAAGTGCTTGAAGTGTAGCAAATCATATAGTTCACATTATTCAGTACTACGCCATCACAAGCAGGTACATGTGGGTGCGCGTGTATTCAAATGCCAACATTGTAGCGCAAGCTTTACGCATGGAAACACTTTAACTTATCATATGGCTAAACATACGGGCATACGTAGCAATAAATGTGACAGATGCCCCAAAGCGTTTGTGCATAGACACGAGTTGATTTTGCACATGCGTACGCATACCGGAGATAAACCTTATTTATGCAAGCATTGCCCTAAAGCCTTTGCACATCGTTCTAATTTGGTCACTCATATGCGTCTGCACTCCGGACAGCTGCCATTTAAGTGTGAAACGTGTGGTGCTTTCTTTAATAGCAGTTCTCATTGGAAACTACACAAAGAAAGACATCTTAAGCATGCGCAAAAGCTTGTCGAATCAAAGTTGaatgaatataaatatgcaaCATTGGTAGGGACTGAAAAAACTCCACGACAATCGTCCAGCACAGTGCCAGATTTTATAACGCCTACATCATCTCTACTGCGTCCGAAAAATACCATTGTAAAATCTGTTAAAATGCTACCACCTATTAATGCGCTCCCGGGACCTAATGCGACTATTAATAGCAGtgagttaaaaaatattatacttAAAAGTATACCCGCAGAAAAAACAAAACCCTCACCTCCACTACGATTTGAATGTACAAAATGTTTGCAACGTTTCAAATTGAGATCTGCATTAACGAAACATCTACGTACACATACAGGAGAAAAGCCCTATCGTTGCCCACTTTGTCCGCGCACATTTGCTGATGCGTCGAATTTTAAACGTCACAAGTCCCTGCATAAAACCGCTACAGAACAGTTACAAAATGTCAGCAAACAATTAAAgacttctaattttttaaatgagcTGCAACGCGGTAAAACAAAACCTATGTCTCTAGCACTTGCTAGTTTATCACCAACTCCTAGCATTGCGTCTGATCCTGATCCTGATGGCTTAGAAGCAATTGCACGTACCAATGCCATTATATCACCTAAAAGTGTTATTAATTTAAGCGATGGTGACGATGCTGATATTATGATGGCTATATTAGATGATGTCGCTGAAGAATCCCTACAACAATTAGCAAGTACAACTAAAATTGCTTTATCTTCCAATACGTCACAACAATTAGTTTGTATATCTTATGCTAATCCGACAAATCCCAGTGATAATAAAACGACATCATTCTATTTGTAA
Protein Sequence: MVPLPSHHQQPKNVFLRRDVSEHIVISEHRAISEYKFDEEHLCRLCGELQQNVISLYGEDREDFVKLVTLTLGYLNIEFTDKDVFPKWLCATCHVHAELTNKFLLMVQEAQIKLREVVQAERETCRYLITELQENNQVIKLESDCLQSPQNLRKHEIFAAKKIEGGKADTQTSMNDSDTAYIKTEEDFAIHFSTMVRNKLQKGPDLSSHNDLQHRSTPQQQALFASNNDTDLYQCHYCGATYKNEHLLNAHLAKHLGKLYFKCNKCTKRFAHNDELTLHMRAHEGDQSSVNEHYRETSACPSNSNQLAQKYELQASTPNATPSDSSLSRTAEKLYNCTICLKKYAHEAHLKAHQNLKHKNISFPFKCAENEIQIWGENRDDFVTLISCTLGYLNIEFVDDDVLPKCICAPCQLDAESTKKFLLLVEEGQRKLRKIVEESYAALGKPSSLQGNRNSNQEESMPYKGNSAESSLNNNCKSLIKLLNTSDNKNVEIEEYPIDIHTSVTDISTSKYPKRKRQPTKRFPCDPTPYAGAEDYASGDDTDTKCDQSGDIRAGTLITIKPIAELCAANGASLAEMIAVDTEVPQRITSTEPEIRLVCEYCKDIFTTQRLFLKHLRTHNETIYQCMECENCYETLTELKKHQKLEQHKGKTILAKSKTKTSNKWTPKKDLKTNSENIAISIALDDDGSIDSDVKPTVKDGDTRSDQVGPNYQTEQIEIKKKGLPSTKTAYKCLKCSKSYSSHYSVLRHHKQVHVGARVFKCQHCSASFTHGNTLTYHMAKHTGIRSNKCDRCPKAFVHRHELILHMRTHTGDKPYLCKHCPKAFAHRSNLVTHMRLHSGQLPFKCETCGAFFNSSSHWKLHKERHLKHAQKLVESKLNEYKYATLVGTEKTPRQSSSTVPDFITPTSSLLRPKNTIVKSVKMLPPINALPGPNATINSSELKNIILKSIPAEKTKPSPPLRFECTKCLQRFKLRSALTKHLRTHTGEKPYRCPLCPRTFADASNFKRHKSLHKTATEQLQNVSKQLKTSNFLNELQRGKTKPMSLALASLSPTPSIASDPDPDGLEAIARTNAIISPKSVINLSDGDDADIMMAILDDVAEESLQQLASTTKIALSSNTSQQLVCISYANPTNPSDNKTTSFYL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -