Basic Information

Insect: Merodon equestris
Gene Symbol: EGR3
Assembly: GCA_958301585.1
Location: OY284413.1:54041525-54049604[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2.2e-07 4.7e-05 25.1 0.2 1 23 704 728 704 728 0.97

2 3 3.9e-06 0.00084 21.2 4.0 1 23 734 756 734 756 0.99

3 3 1.2e-05 0.0026 19.6 0.6 1 23 762 784 762 784 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2.2e-07	4.7e-05	25.1	0.2	1	23	704	728	704	728	0.97
2	3	3.9e-06	0.00084	21.2	4.0	1	23	734	756	734	756	0.99
3	3	1.2e-05	0.0026	19.6	0.6	1	23	762	784	762	784	0.98

Sequence Information

Coding Sequence: ATGATCATGGAAGGGCTTGAAACCCTTGTGGCGCCATCGCATCACGCATTCCTGCTCACCGAATCCGCAGCGGCAGCTCATTTCAATGTTCTGAGCTTTGATACATGCCTCTTTAAAACCACCGCTCAAACAAGTCCATCAACTGCACCCGTTTCCGTATCATCGGGTGCATCATATCTCTCCAATCCGTCTACCTTCGGCGGTGGCTTGGGTGCACAGACTCTCCTCCACTACAGCTTACAGTCATCATcgtcgcaacaacaacaaaaccaaACCAACACAAGCAGCACCGCCACCCAGCATCATAGCCAACAGcatcagcaacatcatccgcaaacAACTGTTTCCGGCAGCATTTCGATTACCCAAAATAACAATATCAGTCGTAATTCAACGCCATCGGGTGTTGTCAGTACTGGAGCATCAGCACAGACAACAACCACCAGTACATCCAGCACTGGACCGGGTAGTAGCGGTTCCGGTCGAAGTTCAGCCTCTCACTTAAGCCTGCTTAATACTGGTTCGAGTGAAGCCAGTAAACACCCGCATacgcaacaacagcaacagcattcacatcaacatcagcaacaGCACCAGCAACACCATCATCCCGGACAGGATAGTAACGACGCACAAACTGGCGATTTGAATACGCCGGTAACAACATCCAGTGATATACCGTCGTTCTTCGGCCCATCAACTGTTGTTGAACCACCGCCAATTACAGGTTCAATTGAATCTGAGGATCTTTCCCTTGAACCGCAAGCCGTCTCAAGTCCAGTGTTGTGTAGTCCATTGAAAGAGGAACGCAGTACACCGCCCACGCTGATAGTTAAGGAAGAAACAAGTAATAATAGTTGTACAATGTATCCAACACATCTCACAAATagtcaaacaacaacaactacattAGGCAACAATAGCAATACACATAACAATAATAGCAATTCAACAAGTGCCAGTAATAGCAATAACACAAATCACCACCATCCACACTCTCAGCATGGTAACACGTCGCCACACCAACATCATAGTCTACAACAACACAGTCAACATATgacgcaacaacaacagcaacaaaaccAAATACACCACAGTCAATTGCATCAACAACATCTGCAACAACATCATAATCACAATACACAacaccatcaacaacaacaacaacaacaccatcaacaacaacatcaccaacaccaacaccaacaacaacatcactCGCAACACCAcgcccaacaacaacaacagcatcaacatcaaagTAGCGGTAAAATATCATATCGTGGCATTTTCACCACTACAGGTAACCCATCAATGGGCGGTCTTgcaacatcagcagcggcagccgcagcagcagcagcagcttcGGCTTCACAACTCAACTCACCACAGTTGAGCGTGTTGCCAAGTCAAATGTCACCACCGTCAGCCGGTTTAGGCAGCAGCTGGGGTCTACCCAGTCCCGATAAAACACTCTTCCAACCGCCAATGTTCAGTCTCTTGGGTCCCGGACCACAAAATACCGGCGCCCAAGCTCATTACGCACCGCAAAATACGTCCACAAGTAGTCCGTCGCCATCCGCCCATCATATGCATTCCGCATACGGTGACGAACGTAACCCGCAGCACGTCGAACTCCTCGGTCTCAATATGGACTGTTCGAGTATCATTCTTAAACAACCACCGCCCAGCTATGGTAGCGGATGCGTCGGCAGCATGGATCTCCAGCCCGGTCAGTCCAGTCAAGACCTGAATCAGTATGCCCGCCAACAAATGAGTGCATCTAAATACCAATGGCTCGATTCGCCCGCTGAATATGGTAGCCCGCAACAATCGCTAGTCGTGCCCGGTCCATCATCGTCCGCCTCGTCCACGTCGGGACTGATCCCAAAACAAGAAGCTTTCAGCGATCATCATATGCAAACGCCATCAGGTTCACAGTCTGGTTACGCTGGCGTTCAACTTGCCGAATACAGTCCATCCACCAGTAAGGGTCATGAGATCCTATCTCAGGTTTATCAACAAAGCGCCATGCCTCTGAAACTGGTTCCGGTCAAGCCGCGTAAATACCCAAATCGGCCGAGCAAGACACCTGTTCACGAACGACCATACGCCTGCCCCGTGGAGAACTGCGATCGGCGATTCTCCCGGTCCGATGAACTCACCCGCCACATTCGCATCCACACCGGCCAGAAACCGTTCCAGTGCCGTATTTGCATGCGATCCTTCAGCCGCTCCGATCACCTAACAACGCACATTCGAACGCACACGGGCGAGAAGCCCTTCTCCTGCGATATTTGCGGCCGAAAGTTTGCCCGCTCCGACGAGAAGAAACGTCACGCGAAAGTCCATCTCAAACAACGTATCAAGAAGGAGAGCAAACTTagtcagcagcagcaacagcatcaaCAAGCGGCAGCAGCGGCGGCAGCTGCAGCAGCAGCCGTacaacatcatcaccagcaaCAGCATGCGCATCATATGCTGCATTCCGGTGACCTATCGATAGTGACAACAAGCGCCACTAGCTTGTAG
Protein Sequence: MIMEGLETLVAPSHHAFLLTESAAAAHFNVLSFDTCLFKTTAQTSPSTAPVSVSSGASYLSNPSTFGGGLGAQTLLHYSLQSSSSQQQQNQTNTSSTATQHHSQQHQQHHPQTTVSGSISITQNNNISRNSTPSGVVSTGASAQTTTTSTSSTGPGSSGSGRSSASHLSLLNTGSSEASKHPHTQQQQQHSHQHQQQHQQHHHPGQDSNDAQTGDLNTPVTTSSDIPSFFGPSTVVEPPPITGSIESEDLSLEPQAVSSPVLCSPLKEERSTPPTLIVKEETSNNSCTMYPTHLTNSQTTTTTLGNNSNTHNNNSNSTSASNSNNTNHHHPHSQHGNTSPHQHHSLQQHSQHMTQQQQQQNQIHHSQLHQQHLQQHHNHNTQHHQQQQQQHHQQQHHQHQHQQQHHSQHHAQQQQQHQHQSSGKISYRGIFTTTGNPSMGGLATSAAAAAAAAAASASQLNSPQLSVLPSQMSPPSAGLGSSWGLPSPDKTLFQPPMFSLLGPGPQNTGAQAHYAPQNTSTSSPSPSAHHMHSAYGDERNPQHVELLGLNMDCSSIILKQPPPSYGSGCVGSMDLQPGQSSQDLNQYARQQMSASKYQWLDSPAEYGSPQQSLVVPGPSSSASSTSGLIPKQEAFSDHHMQTPSGSQSGYAGVQLAEYSPSTSKGHEILSQVYQQSAMPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKESKLSQQQQQHQQAAAAAAAAAAAVQHHHQQQHAHHMLHSGDLSIVTTSATSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00241169;
90% Identity: iTF_00689037;
80% Identity: -