Mequ027354.1
Basic Information
- Insect
- Merodon equestris
- Gene Symbol
- ZNF438
- Assembly
- GCA_958301585.1
- Location
- OY284415.1:12816745-12819093[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.62 1.3e+02 4.8 5.4 1 23 214 237 214 237 0.94 2 14 0.0087 1.9 10.6 2.5 1 23 246 269 246 269 0.96 3 14 2e-05 0.0044 18.9 1.0 2 23 276 298 275 298 0.95 4 14 0.8 1.7e+02 4.4 0.2 3 11 307 315 306 325 0.91 5 14 0.61 1.3e+02 4.8 2.7 2 23 345 366 344 366 0.97 6 14 0.076 17 7.6 2.1 1 14 372 384 372 395 0.81 7 14 0.00092 0.2 13.7 2.8 2 23 404 425 404 425 0.98 8 14 0.13 29 6.9 1.3 3 21 435 453 433 456 0.87 9 14 0.0032 0.7 12.0 3.2 1 20 463 482 463 486 0.94 10 14 3.4e-07 7.4e-05 24.5 1.6 1 23 492 514 492 514 0.98 11 14 1.4e-07 3.1e-05 25.7 0.3 3 23 521 541 519 541 0.97 12 14 0.0075 1.6 10.8 2.5 1 23 547 569 547 569 0.98 13 14 0.011 2.5 10.2 7.6 1 23 574 596 574 596 0.98 14 14 0.00026 0.056 15.4 0.1 1 23 601 624 601 624 0.97
Sequence Information
- Coding Sequence
- ATGGAATCACCATTGGTGTGTCGTGCGTGTTTAACTACAATTTCCCTAGAGTACATCGATTTGGAAACTCCCATCCAGGATAATATAACCTTCTTAGATTGCTTCAAGTTTTGCACCAAACTTGAAGCGTATTTAGACGATGAATTACCAAATAATATATGCGTGTCTTGTGGCAAATCACTGCAGATAGCTTATGAGTTTATCAAATCGTCTATGGAAGCTGATCGCGCTCTGCGACAGAGTTTGTCATTATTCGGCGATTTATACCATTTGCAAGAGTACAAGTGTAGAACATCCGGTGATAGATTCTTGATAAAGAAGGAAGAAGATAATCATGGTAATTCAGAGCTCGAATTTCATGCAATATGCGAGGAAGACTTTAATTACTTTGAAATTAAGAAGGAAAAAGATAATCAAGAATTTCCCTTGTTCGAAGTGGTCATTTCTAATGAAGACATCGTCGCTGATGGATGCAATGATATGTTAACTGCAGATGACGACGAGAACACATGGACAGAAGCTGGAGTCGAGCATGACATATTAGACGAGGAGACCGATAAAAGTTGTCCTAGTTGCAGTAAGCAAATTCCCAATGACGAATACGACGGGCACATAAACATGCATAAAGGTCAAAAGCCTTACAAGTGTGATGAGTGTGACGAAAAGTTTTTCTGCAAGAAGAAAATGGAAATCCACAAGAAGTCAAAACATAAATACGCCCAGCAGcaaaacaattatgtttgtGGATGGTGTGGCGAAACGTTCGACTGTAGATCGAAATTATGCCAACATCGCTTGATAGATCATCGCGGCAAGGTACCGAAATCTTGTTTAACTTGTGGAGAAAAATTCTCGGATGAGGCCAACTTGCGACGCCACGTTAAGAGGAAACATGGAGCCCCAAAGAAGCCGGTGTTATGCACGTATTGCAACAAGGAATTTAAGGGAATAGCACTTCATATAAAGAGTAACCATCCGGACGTGTTGGGAATCCCCTTGCCTGAGGACGGAAACGCCAAACTATCTCGAAACCAATGTCCGTACTGCTTTCGTTACTGCCAAAGCAGAAATATTCTAAATGACCATCTCAACACGCACACAGGTGAGCGACCGTATTCATGCTCGCTTTGTGGTAAgacatttcataaaaaaaacatttgcgaTAGGCACGTACGTTTAGTGCATCAAGCTAAAGACGCGCCCAGAGAGAAATGCGAATACTGTGACTTCACAACAACCAACATCGCCTCGCTAAAATCGCACATGCATCGTCATCGAAAGCCAGTCGAAAAGAAACACCTGTGTTCCTTTTGCCCTATGAAGTTCATCAATCCGAAGATGCTGTACATGCACGAAGAGTTTAAGCACCGCAACGCGGAGAAGACGTACGAGTGTGATATTTGCCAGAAAAAATTCTCGATCAAACGAAAGTTGAAAGAACACAAGATGTGTGTACACGTTGAGGGAAGACCGTACCAATGTCCAGAGTGTAATAAAACCTTCAAAAACGACTTCCAATTGAAAGCACATCAAAAGCTACACACTGATCGGCAAATCGACTGTCCGCAGTGTGAAAAGAAGTTCGCTCGGCAAGCTGATCTCAAGATTCACATGCGAACGCATACGGGCGAATTGCCCTACGAGTGCCACCTCTGCGAGAAGCGATACGCGATTAAGGTCAGGCTTACCTATCACCTGCAAAAACATATGGGCATCAAGCACAAGTGCCAGCATTGCTCTAGTGAGTTCAATAGTCGATCCAAGCTCAGATTGCACATGTTCAAGCACATCGGTATGCCGTACAGCTGCGACACTTGCAATGTCGGATTTCCCAATCGAGTCGGCTTACGTCGTCACGCGAAAAGTGCACACAAGATTATCCTAACCGTGGACGACCTATTAGAAAATCGCCGCAAAAACGAAAAGTATATGATCAAAGACATAGAAAGTGCTAGTCTTCTACTTCCGCAAAACACTTCCGGCGTCGAGGACGAAATGGAAATTTAA
- Protein Sequence
- MESPLVCRACLTTISLEYIDLETPIQDNITFLDCFKFCTKLEAYLDDELPNNICVSCGKSLQIAYEFIKSSMEADRALRQSLSLFGDLYHLQEYKCRTSGDRFLIKKEEDNHGNSELEFHAICEEDFNYFEIKKEKDNQEFPLFEVVISNEDIVADGCNDMLTADDDENTWTEAGVEHDILDEETDKSCPSCSKQIPNDEYDGHINMHKGQKPYKCDECDEKFFCKKKMEIHKKSKHKYAQQQNNYVCGWCGETFDCRSKLCQHRLIDHRGKVPKSCLTCGEKFSDEANLRRHVKRKHGAPKKPVLCTYCNKEFKGIALHIKSNHPDVLGIPLPEDGNAKLSRNQCPYCFRYCQSRNILNDHLNTHTGERPYSCSLCGKTFHKKNICDRHVRLVHQAKDAPREKCEYCDFTTTNIASLKSHMHRHRKPVEKKHLCSFCPMKFINPKMLYMHEEFKHRNAEKTYECDICQKKFSIKRKLKEHKMCVHVEGRPYQCPECNKTFKNDFQLKAHQKLHTDRQIDCPQCEKKFARQADLKIHMRTHTGELPYECHLCEKRYAIKVRLTYHLQKHMGIKHKCQHCSSEFNSRSKLRLHMFKHIGMPYSCDTCNVGFPNRVGLRRHAKSAHKIILTVDDLLENRRKNEKYMIKDIESASLLLPQNTSGVEDEMEI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -