Mmel068848.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010000567.1:814896-816995[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00089 0.1 16.5 0.5 1 23 19 42 19 42 0.96 2 19 3.9 4.5e+02 5.0 4.1 1 23 107 130 107 130 0.97 3 19 0.016 1.8 12.6 1.5 1 23 136 159 136 159 0.98 4 19 0.097 11 10.1 0.4 1 23 165 188 165 188 0.98 5 19 0.069 8 10.6 3.1 1 23 195 218 195 218 0.98 6 19 0.002 0.24 15.4 2.1 1 23 250 273 250 273 0.98 7 19 0.019 2.3 12.3 5.0 1 23 279 302 279 302 0.98 8 19 0.048 5.6 11.1 1.3 1 23 308 331 308 331 0.96 9 19 0.048 5.5 11.1 1.9 1 23 337 360 337 360 0.98 10 19 0.0065 0.76 13.8 1.9 1 23 366 389 366 389 0.96 11 19 0.004 0.47 14.5 1.5 1 23 423 446 423 446 0.98 12 19 0.11 13 9.9 1.2 1 23 452 475 452 475 0.97 13 19 0.023 2.6 12.1 1.1 1 23 482 505 482 505 0.98 14 19 0.0011 0.13 16.2 0.8 1 23 511 534 511 534 0.98 15 19 0.01 1.2 13.2 3.8 1 23 540 563 540 563 0.98 16 19 3.9 4.5e+02 5.1 2.4 1 23 569 592 569 592 0.97 17 19 0.073 8.5 10.5 0.6 1 23 599 622 599 622 0.98 18 19 5.4 6.3e+02 4.6 2.6 1 23 628 651 628 651 0.97 19 19 3.7 4.3e+02 5.1 0.0 1 21 658 678 658 679 0.95
Sequence Information
- Coding Sequence
- ATGTACAACGCCGACTTCAGGCATCACACTAACGAGCATTGCAGGGTGAAAATGTACAAATGTGGAATTTGTAACAGAAGATATAAGGCGAAGGAATCTCTCAAGGTGCACGTGGAAAAAGTTCATATTGACTGTGAAAGAGGGGATGCCCAAAAATACTCTAGTTGTGACAATTTCAAAGCTAGTATTAAAAATATAAGACAGAGATCTTTACACTCACGTGCTGATGGAGAACAATGTCAGTGTTCAAAATGCAAATTTCAAACGAGGAAAAAATGTTACCGAAAATCAAAAATAAAACACCTGAACAGAGGCAAATATAAATGCACAAATTGCGAGTATAAGATACGTTGTAGGACTTCTTTAGAAAGGCACGTGAAAATAAAACATCTCATGGAAAGTAACTATAAATGCGCAAAGTGTGAATTCGAAACAAAGTACAGGGGAAATTTAGGAAGACACATAAAGAGAAGACATGTTAAAGAAAAAGCTTACAAATGCGTGGAGTGCGAATTCAAGGCAAACATTAAGTCAGATTTAGAAATACACATTAAAAGAAAACATCTGGAACAAAAAAATAATTATAAATGCCTAGAGTGTGAATTCAAGACAAACTTCAAGTCATATTTAAAAATCCACGTAAAACGAAAACATTTGGAACAATATAATTATAAATGTGGAGAGCGTGAATTCAAGATAAACACGAAGTCAGATTCAGAAGGAAAAAATCTGGAACAAAAGAATAATTATAAATGCCTTGAGTGTGAATTCAAAACAAACAACGAGGAAAATCTAAAAAAACACATTAAAAGAAAACATCTCGAACAAAATGATTATAAATGTACGAAGTGTGAATTCAAGACAAACTTCAAGTTTGACTTGCAAAGACACATAAAAAGAAAACATCTGGAACAAACTGATTATAAATGCGCTGAGTGTGAATTCAAGACAAACTTAAAGTTTGAGTTACAAAGACACATAAAAGGAAAACATCTGGAGCAATATGATTATAAATGCGCAGAGTGCGAATTCAAGACAGACTTCAAGTCATACTTACAAATACACGTAAAAAGAAAACATCTGGAACAAAATGATTATAAATGTACAGAGTGTGAATTCAAGACAAACTTAAAGTATGACTTACAAAGACACATAAAAGGAAAACATCTGGAACAAGATTATAAATGTGCGGAGGGTGAATTCGAGGCGAACATCAAACCATATTTAAAAAGCCACATAAAACGAAAACATCTCGAACAAAATGATTATAAATGTGCAGAATGTGAATACAAGACAAACATTAAGTCAAATTTAAAACTACACATAAAACGAAAACATCTCGAACAAAATGATTATAAATGCACAGAGTGTGAATTCAAGACAAACATCAAGATAGACCTAGAAAGACACGCAAAAAGAAAACATCTGGAACACAAAAATAGTTATAAATGCCTGGTGTGTGAGTACAAAACAAGCATCAAGCCAAATTTGAAACTACATATAAAACGAAAACATCTAGAACAAAATGATTATAAATGTGCAGAGTGTGAATTCGTGACAAACATGAAGTCAAATTTAAATGCACACTTAAAGCGAAAACATCTGGAACAAAATGATTATAAATGTACAAACTGTGAATTCAAGACAAACTTCAAGATAGACTTACAAAGACACATGAAAAGAAAACATCTGGAACAGAATGATTACAAATGCGCAGAGTGTGATTTCAAGACGCACCTCAAGTCATACTTACCAATACACATAAAAAGGAAACATCTGGAAGAAAAAAATATTTATGAATGCCTAGAGTGTGAGTTCAAAACAAATATCAAACCAAATTTAAAAGTACATATAAAAAGAAAACATCTGGAACAAAACGATTATAAATGTGTAGAGTGTGATTTCAAGACACACCTCAAGTCATATTTGCCAATACACATAAAAAGAAAACATCTGGAACAAAGAAAGAATTATGAATGCCTGGAGTGTGAGTTCAAAACAAATATCGAGCCAAATTTAAAAGTACATATAAACGAAAGCATCTGGAACAAAATGATTATAAATGCGCAGAGTGTGAATTCAAGACAAACATCCAGATAG
- Protein Sequence
- MYNADFRHHTNEHCRVKMYKCGICNRRYKAKESLKVHVEKVHIDCERGDAQKYSSCDNFKASIKNIRQRSLHSRADGEQCQCSKCKFQTRKKCYRKSKIKHLNRGKYKCTNCEYKIRCRTSLERHVKIKHLMESNYKCAKCEFETKYRGNLGRHIKRRHVKEKAYKCVECEFKANIKSDLEIHIKRKHLEQKNNYKCLECEFKTNFKSYLKIHVKRKHLEQYNYKCGEREFKINTKSDSEGKNLEQKNNYKCLECEFKTNNEENLKKHIKRKHLEQNDYKCTKCEFKTNFKFDLQRHIKRKHLEQTDYKCAECEFKTNLKFELQRHIKGKHLEQYDYKCAECEFKTDFKSYLQIHVKRKHLEQNDYKCTECEFKTNLKYDLQRHIKGKHLEQDYKCAEGEFEANIKPYLKSHIKRKHLEQNDYKCAECEYKTNIKSNLKLHIKRKHLEQNDYKCTECEFKTNIKIDLERHAKRKHLEHKNSYKCLVCEYKTSIKPNLKLHIKRKHLEQNDYKCAECEFVTNMKSNLNAHLKRKHLEQNDYKCTNCEFKTNFKIDLQRHMKRKHLEQNDYKCAECDFKTHLKSYLPIHIKRKHLEEKNIYECLECEFKTNIKPNLKVHIKRKHLEQNDYKCVECDFKTHLKSYLPIHIKRKHLEQRKNYECLECEFKTNIEPNLKVHINESIWNKMIINAQSVNSRQTSR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00990778; iTF_00990727;
- 90% Identity
- iTF_00990778; iTF_00990727;
- 80% Identity
- -