Basic Information

Gene Symbol
-
Assembly
GCA_935421255.1
Location
CAKXYX010000542.1:818265-821972[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2.3 2.6e+02 5.8 3.5 1 23 131 153 131 153 0.97
2 16 0.0018 0.21 15.5 1.2 1 23 159 182 159 182 0.96
3 16 0.85 99 7.1 5.0 1 23 249 272 249 272 0.97
4 16 1.4 1.6e+02 6.5 1.1 1 17 278 294 278 295 0.93
5 16 0.0024 0.28 15.1 2.4 1 23 371 394 371 394 0.96
6 16 0.00069 0.081 16.9 1.5 1 23 400 423 400 423 0.97
7 16 0.0055 0.65 14.0 2.9 1 23 429 452 429 453 0.95
8 16 0.048 5.5 11.1 0.2 1 23 458 481 458 481 0.98
9 16 0.04 4.6 11.3 1.3 1 23 487 510 487 510 0.98
10 16 0.099 11 10.1 1.9 1 23 516 539 516 539 0.95
11 16 0.0074 0.86 13.6 1.4 1 23 545 568 545 568 0.95
12 16 0.00024 0.028 18.3 1.8 1 23 574 597 574 597 0.98
13 16 0.0056 0.65 14.0 0.4 1 23 603 626 603 626 0.94
14 16 0.00071 0.082 16.8 0.9 1 23 632 655 632 655 0.98
15 16 0.0025 0.29 15.1 4.0 1 23 661 684 661 684 0.98
16 16 0.022 2.5 12.1 3.1 1 23 690 713 690 713 0.97

Sequence Information

Coding Sequence
ATGGCTAAACGAAAATCGGAAAAAGATGACGCTTTGACTATACTGGAGACAGTTATCGAGTTTTGTGAGGAAGAGAAACGAACAGGCCACTATGCTTTTCCTGTAGAGCAAGTCATTAGAAGAGTAGCTGCAATGACAGGAAAATCAGAAAAAAATACAAAGCGTATCAAAACCAATTTACGCAAGAGTTTGGAGGACCAGTCTTCATCTTCTACTATCCATATACAGCCAAGAAAGGAGAAAAAGTCCAAAATTATATTAGATGATGCGGACAAATCTGTATTGCGGAACAAGATCACATCTATGTACACTGTCACGCAGGTTCACGAGCTAGATACAGAAACGCCTTCATCTTTAAGAAGCAAGCTCAAACGATGGAAGCATGGAATATACAAATGTACGCAGTGCAAGTTCAGGACAATGTACAACGCCGACTTCAGATACCATACTAACGAGCATTATGAAGGGAAAATGTATAAGTGTGAAATTTGTCGCAGAAGATACAAGGCAAGAAAATCTCTTGAGACGCACATGGTAAAAATACATGCTGACAATGCAGGAAGAGACGTCCCAAGTTACTCTACGTGTGACTATATCAAAGATAATGTTAAAAATAAGAAAGAGATATCTACACGCTCACATGCCGATAAAAAACAATGTCCGTGCTCGAAACGCAAATTGCAAATAAGGAAGAAATGTCACTTAAAACCACATATAAAAATAAAACATCCCAGCAGCGGCAAATATAAGTGCGCTCATTGCGAGTTTAAGACATATTACAGCACCTATTTAAAAATGCATGTGAAAATGAAACATCTCATAGAAAGTTATTACAAATGCAAGGACTGTCAATACCAGACGAACTTCAAGTCAAGTTTGGAAGTATACACGAAGGCAAAACATCTGAAACAAAAGGATTATAAATGCGCAGAATGTGAGTATAATACAAACCACCTTCTTTGTTTAGAAAAACAAATTAAAAAATGCGATTATAAATGCGAAGAACATCTTAAACAACACGATTGTAAATGCACAGAGTGTGAATACAAGACAAGTAGGAGTACATGTTCCAAAGCACACATAAAGACGAAACATCTTAAAGTAACTGATTATAAATGCATGGAGTGTGAATTCAAGACAAATCGCAAGTCACACTTAGAAAGGCACGTAAAAGCAATACACCTGAAGCAAAAGGATTATATATGCGCAGAGTGTGAATACAAGACAAGCCAAAAGTCATGTTTAGAAAAACACATACAGACAATACATCTTAAAGTAACTAATTATAAATGCGCAGAGTGTGACTACAAGACAAACTACAAGCCAAATTTAAAAAAACACGTGAAAGCAAAACATCATAAACAATACGATTATAAATGCGCAGAGTGTGAATTCGAGACAGGCAATAAGTTATATTTACAAATACACATAAAAACAATACATCTTAAATTATGGGATTATAAATGCATGGAGTGTGAATACCAGACGAACATCAAGACAAATTTGGAAACGCACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCATGGCGTGTGAATTCAAGACAAATCGCAAGTCACACTTAGAAACACACGTAAAAGCAATACACCTGAAACAAAAGGATTATATATGTGCGGAGTGTGAATACAAGACAAGCCAGAAGTCATGTTTAGAAAAGCACGTAAAGGAAATACATCTTAATGTAACCGATTATGAATGTGCAGAGTGTGAATACAAGACAAACCACAAGGCAAATTTAGAAAGACACATAAAGACAAAACATCTTAAAGTAACCAATTATATATGCGAAGAGTGTGACTACAAGACAAACCTAAAGCAAAATTTAAAAAAACACGTAAATGCAATACATCTTAAACTAAACGATTATAAATGCGCGGAGTGTGAATACAAGACAGGCAATAAGGCACATTTAGAAAATCACATAAAAACGATACATCTTAAAGTATACGATCATAAATGCATGGAGTGTGAATACAAGACAAACTACAAGTCTAGTTTAAGGAAACATATAAAGACGATCCATCTTAAAATAAGCGATCATAAATGTGCAGCATGTGAATACAAGACAAACTACAAATCTAGTTTAGAAAGACACATAAAGACAAAGCATTCTAAAGAAGGCGATTATAAAGGTACCGGTTGCGAATACAAGACGCAAAAATAA
Protein Sequence
MAKRKSEKDDALTILETVIEFCEEEKRTGHYAFPVEQVIRRVAAMTGKSEKNTKRIKTNLRKSLEDQSSSSTIHIQPRKEKKSKIILDDADKSVLRNKITSMYTVTQVHELDTETPSSLRSKLKRWKHGIYKCTQCKFRTMYNADFRYHTNEHYEGKMYKCEICRRRYKARKSLETHMVKIHADNAGRDVPSYSTCDYIKDNVKNKKEISTRSHADKKQCPCSKRKLQIRKKCHLKPHIKIKHPSSGKYKCAHCEFKTYYSTYLKMHVKMKHLIESYYKCKDCQYQTNFKSSLEVYTKAKHLKQKDYKCAECEYNTNHLLCLEKQIKKCDYKCEEHLKQHDCKCTECEYKTSRSTCSKAHIKTKHLKVTDYKCMECEFKTNRKSHLERHVKAIHLKQKDYICAECEYKTSQKSCLEKHIQTIHLKVTNYKCAECDYKTNYKPNLKKHVKAKHHKQYDYKCAECEFETGNKLYLQIHIKTIHLKLWDYKCMECEYQTNIKTNLETHIKSKHLKLHDYKCMACEFKTNRKSHLETHVKAIHLKQKDYICAECEYKTSQKSCLEKHVKEIHLNVTDYECAECEYKTNHKANLERHIKTKHLKVTNYICEECDYKTNLKQNLKKHVNAIHLKLNDYKCAECEYKTGNKAHLENHIKTIHLKVYDHKCMECEYKTNYKSSLRKHIKTIHLKISDHKCAACEYKTNYKSSLERHIKTKHSKEGDYKGTGCEYKTQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-