Mmel087078.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010000762.1:17937-25853[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.46 54 8.0 3.7 1 23 347 369 347 369 0.98 2 13 0.011 1.2 13.1 2.9 1 23 375 398 375 398 0.98 3 13 0.00035 0.041 17.8 0.6 1 23 404 427 404 427 0.96 4 13 0.0032 0.37 14.8 1.8 1 23 433 456 433 456 0.96 5 13 0.00027 0.031 18.2 0.6 1 23 462 485 462 485 0.96 6 13 0.00034 0.039 17.8 2.3 1 23 491 514 491 514 0.98 7 13 0.36 42 8.3 1.1 1 23 520 543 520 543 0.96 8 13 0.0055 0.64 14.0 3.3 1 23 549 572 549 572 0.96 9 13 0.0094 1.1 13.3 1.0 1 23 578 601 578 601 0.95 10 13 0.00051 0.06 17.3 1.6 1 23 607 630 607 630 0.98 11 13 0.0034 0.4 14.7 0.8 1 23 636 659 636 659 0.96 12 13 0.0006 0.07 17.0 1.7 1 23 665 688 665 688 0.98 13 13 0.021 2.4 12.2 1.8 1 23 694 717 694 717 0.96
Sequence Information
- Coding Sequence
- ATGCCTCCGAATGTAACAGCTCTTATACAGCCCATGGACCAGAATGTCATTAGGTTAACAAAATTGTTTTATAGAAGAAGCCTTTTATCCACAATAGTTGCTTCTGATAACAATGCTATTTCAGCTGTCATTCAAAATTTGAGTCTAAAAGATGCTGTTACACATCTGGCATTAGCATGGATGAATGTGAAAGAAGAAATAATTGCTAAGTGTTGGAAAAATATTTTATCAGATTCTTTCAATAGCGACTCTGATTCAGAAGAAGATGTTCCATTGGCTATTCTACAAGAAAAATACAAGAACAGCGTCGAGGCAGTGACATTTCAAGAAACTGTAGCATTACTACAGAAAGTGAACGGAAACATAACATACAGCTGTAAAGACATAGAAAACTGGAATACGGATATCATAGAAGATCTTGAAGAGGATGTAATTGAAATTGAAAGTGCGGAAGAAACAATGGATGATGAGCCAATGCCAACTACCATCCCCACTCAGGAAGCTTTACAAAGACTTAATATAGTACAAAAAGACGCAGATACGTATTTCACCTTTCTACAGGATCGTCGGTACGCCCCTGCTGGAGAAGAGATACATTCAACCAAACATAACTACCTTGCTATCAACCAGAAATTATTAAGACAGAGCGTGAAAGAATATTCAGCGCTAGACGCAGATACGTATTTCACCTTTCTACAGGATCGTCGGTACGCCCCTGCTGGAGAAGAGATACATTCAACCAAACATAACTACCTTGCTATCAACCAGAAATTATTAAGACAGAGCGTGAAAGAATATTCAGCGCTAGACGCAGATACGTATTTCACCTTTCTACAGGATCGTCGGTACGCCCCTGCTGGAGAAGAGATACATTCAACCAAACATAACTACCTTGTTATCAACCAGAAATTATTAAGACAGAGCGTGAAAGAATATTCAGCGCTATACTCCGTACCTCCTGTACCGAAGGTTTACGAGGCTGAAATAGCAAAGCCTTTATCTCTAAGAAGCAAGGCCGAAATACGGAAGCGTAGAATATACAAATGTACGCAATGCAAATTCAGAACAATGTACAACGCCGACTTCAAGCGCCACACTAACGAGCATTGCCAGGTGAAAAAATACGAATGTGGAATTTGTCACAGGAGATACAAGGCGAAAAGATATGTCAAGGTGCACATGAACACGAAGCATCTTGGAGAAAGAAATTATAAGTGCGTAGGGTGTGAATACAAGACAAAGAGCAATTCAAATTTACAAGCGCATATAAAAGCAAAGCATCTTAAAGCAAATGATTATAAATGCACAGAGTGTAAATATATGACAAACTACAAGTCAAGCTTAGTAACACACATAAAAGCAAAACATCTGGAACAGAATGATTATAAATGCGCAGGGTGTGAATACAAGACAAATAACAAGTCAAATTTACAAGCGCATATAAAAGCAAAGCATCTTGAAGGAAATTATTATAAATGTACAGAGTGTGACTATAAGACAAACTACAGGTCGGGTTTGCAACAACACATAAAAACAAAACATCTCGAAAAAAAAGATTATAAATGCACTGAATGTGTATTCAAGACAAACTACAAGTCAAGTTTACCAGCGCACATGAAAGCAAAGCATCTTAAAGAAAATGATTATAAATGCTCAGAGTGTGAATTCAAGACAAACTCCAAATCGCATTTAAAAGTACACTTACAAGCAAAACATCTTGAAAAAAATGATTATAAATGTGCAGAGTGTGAATTCAAGACAAATTACAAGTCAAATTTACAAGTACACGTGAAAGCAAAACATCTTAAAGGAAAATATTATAAATGCACAGAGTGTGAATACAAGTCAAACTACAAGGCAAATTTACAAGTCCACATAAAAACAAAACATCTTAAAGAAAAATATTATAAATGCACAGAGTGTGAGTACAGGTCAAACTACAAGGTTAATTTACAAGTACACATAAATGCAAAGCATTTTAAAGAACATGATTATAAATGCACAGAATGTGAATACAAGACAAATTACAAGTCAAGTTTACAAGTACACATAAAAGTAAAGCATCTTAAAGAAAATGATTATAAATGCACAGAATGTGAATACAAGACAAATTACAAGTCACGCTTAAGAGAACACATAAATGCAAAACATCTTGAAGGAAATGATTATAAATGCACAAAGTGTGAATTTAAGACAAAATACAAGAAAGATATTGATCTTCTTTCATTGGATAGAGAGTGGCGATTATTGCAAAACAGTGACTTCAATGAGGATGCAGCCGATTATATTTCTTTTTGGAAAAATATCTGTAATCAAATTAGATGTGACAGTACTGCTGTTTATCCAGAACTATCAAAATTTGTCAATTTATTTTTAACATTACCTCACAGTAGTGCTTCGGTAGAAAGAATATTCAGTGCAGTATCTCTCAACAAAAGTAAAATCAGAAATCGGTTATCTGCTACTACCTTAACTGGAATTCTACACTCTAAGAGATTAATAAATAGTGATAATAAATCATCGTTAAAAATGTCTCAAGAAATTGCTAAATTTAATTTGAACAACGGAATATCTTTGGAAAATCCATGTAATATAAAAGAAGAATTCCAGGATGAGTATTATGCAGATGATAAGGAATGCATCTCTGAAACAGCTATCATAGATGCTATTAATATAGGCGGTACTAAAATGAATGATTATATGAGGAAAGGCAAAATAGAAAAATGTGAAATACCTTCTGTAGATCTTATTAAAACAGACTTACCATCAATGGAAGTAAATGATACAGTAAGCCACGATGTCAAAGGAGAAAAAGGAATTTGCACTCCTTATGTAGAGATTAAATTCTCCAATGAACTCCGCTTTTGTAACCATTGCCATGAAGTATATCAGGATTATTGCACCAAATGCAGAGTGCTCGTACATATTTTGAACAGAAAGCACTCTCATACTACATGTAACAGAATAAGAGAATTACCAACATATACACTAGAGGCTAGAAAGTCAATTGGACATTTGGGAATCTTTTCTTTAAAAGTTATACCTGAAGATGTAATATTTGGTCCTTTCACTGGAGTTAATTCCACAGGACTGCCTTTGAGAATAAAAGAAGGAAGGTTTGTGGTTAGCGATGATAAATTGGAACATCTGAATTGGATGCAGTTCATCAACCCTGCTAGAAATATTTCCGAACAAAATTTGTTCCCATTTCAATATGAAGACAAGCTATATTATTGTAGCACTCGTAGAATCCAGGAGGAGGAAGAGTTATTGGTATATTTCGGTGAAGATTATGAAGATAGTCTGTTAAAAAATGTGGAAATGGAATTTGTTTCAATCACAAAAAATTTTATTGGAAATGTATTTGCCTGCATTTTCTGTTGCTTAGGATTTAGTTCAAAGGAGTATCTAGCTGAACATAAAGCTGTGTCTCATAGTGAAAGTTACGAAATGTTTTTGATTGAAGGTAGGATGAATTATTATATAATATTCAAAATTAATAGCTTTTGTATCAAAATGTATGTATAG
- Protein Sequence
- MPPNVTALIQPMDQNVIRLTKLFYRRSLLSTIVASDNNAISAVIQNLSLKDAVTHLALAWMNVKEEIIAKCWKNILSDSFNSDSDSEEDVPLAILQEKYKNSVEAVTFQETVALLQKVNGNITYSCKDIENWNTDIIEDLEEDVIEIESAEETMDDEPMPTTIPTQEALQRLNIVQKDADTYFTFLQDRRYAPAGEEIHSTKHNYLAINQKLLRQSVKEYSALDADTYFTFLQDRRYAPAGEEIHSTKHNYLAINQKLLRQSVKEYSALDADTYFTFLQDRRYAPAGEEIHSTKHNYLVINQKLLRQSVKEYSALYSVPPVPKVYEAEIAKPLSLRSKAEIRKRRIYKCTQCKFRTMYNADFKRHTNEHCQVKKYECGICHRRYKAKRYVKVHMNTKHLGERNYKCVGCEYKTKSNSNLQAHIKAKHLKANDYKCTECKYMTNYKSSLVTHIKAKHLEQNDYKCAGCEYKTNNKSNLQAHIKAKHLEGNYYKCTECDYKTNYRSGLQQHIKTKHLEKKDYKCTECVFKTNYKSSLPAHMKAKHLKENDYKCSECEFKTNSKSHLKVHLQAKHLEKNDYKCAECEFKTNYKSNLQVHVKAKHLKGKYYKCTECEYKSNYKANLQVHIKTKHLKEKYYKCTECEYRSNYKVNLQVHINAKHFKEHDYKCTECEYKTNYKSSLQVHIKVKHLKENDYKCTECEYKTNYKSRLREHINAKHLEGNDYKCTKCEFKTKYKKDIDLLSLDREWRLLQNSDFNEDAADYISFWKNICNQIRCDSTAVYPELSKFVNLFLTLPHSSASVERIFSAVSLNKSKIRNRLSATTLTGILHSKRLINSDNKSSLKMSQEIAKFNLNNGISLENPCNIKEEFQDEYYADDKECISETAIIDAINIGGTKMNDYMRKGKIEKCEIPSVDLIKTDLPSMEVNDTVSHDVKGEKGICTPYVEIKFSNELRFCNHCHEVYQDYCTKCRVLVHILNRKHSHTTCNRIRELPTYTLEARKSIGHLGIFSLKVIPEDVIFGPFTGVNSTGLPLRIKEGRFVVSDDKLEHLNWMQFINPARNISEQNLFPFQYEDKLYYCSTRRIQEEEELLVYFGEDYEDSLLKNVEMEFVSITKNFIGNVFACIFCCLGFSSKEYLAEHKAVSHSESYEMFLIEGRMNYYIIFKINSFCIKMYV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -